Carmen G Hernandez-Valencia, Griselda Rodriguez-Martinez, Andres M Carriles-Perez, Daniel Gonzalez-Perez, Carmina Ortega-Sanchez, Marco A Andonegui-Elguera, Yessica Zamudio-Cuevas, Javier Fernandez-Torres, Miguel A Hernandez-Valdepena, Miquel Gimeno, Roberto Sanchez-Sanchez
BACKGROUND/AIM: Enzyme-mediated grafting of poly (gallic acid) (PGAL) and L-arginine and a-L-lysine onto PGAL produces reactive oxygen species (ROS)-suppressor multiradical molecules with low cytotoxicity, high thermostability and water solubility with cancer treatment potential. This study examined the anticancer effects of these molecules in hepatic (HepG2, ATCC HB-8065), breast (MCF7, ATCC HTB-22), and prostate (PC-3, ATCC CRL-1435 and DU 145, ATCC HTB-81) cancer cell lines, as well as in fibroblasts from healthy human skin as control cells...
March 2024: Anticancer Research