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https://www.readbyqxmd.com/read/29775814/composite-self-expanding-bioresorbable-prototype-stents-with-reinforced-compression-performance-for-congenital-heart-disease-application-computational-and-experimental-investigation
#1
Fan Zhao, Wen Xue, Fujun Wang, Laijun Liu, Haoqin Shi, Lu Wang
Stents are vital devices to treat vascular stenosis in pediatric patients with congenital heart disease. Bioresorbable stents (BRSs) have been applied to reduce challenging complications caused by permanent metal stents. However, it remains almost a total lack of BRSs with satisfactory compression performance specifically for children with congenital heart disease, leading to importantly suboptimal effects. In this work, composite bioresorbable prototype stents with superior compression resistance were designed by braiding and annealing technology, incorporating poly (p-dioxanone) (PPDO) monofilaments and polycaprolactone (PCL) multifilament...
May 8, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29775143/testing-the-effectiveness-and-the-contribution-of-experimental-supercharge-reversed-end-to-side-nerve-transfer
#2
Mustafa Nadi, Sudheesh Ramachandran, Abir Islam, Joanne Forden, Gui Fang Guo, Rajiv Midha
OBJECTIVE Supercharge end-to-side (SETS) transfer, also referred to as reverse end-to-side transfer, distal to severe nerve compression neuropathy or in-continuity nerve injury is gaining clinical popularity despite questions about its effectiveness. Here, the authors examined SETS distal to experimental neuroma in-continuity (NIC) injuries for efficacy in enhancing neuronal regeneration and functional outcome, and, for the first time, they definitively evaluated the degree of contribution of the native and donor motor neuron pools...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29773399/dual-physically-crosslinked-healable-polyacrylamide-cellulose-nanofibers-nanocomposite-hydrogels-with-excellent-mechanical-properties
#3
Jiabao Niu, Jianquan Wang, Xiaofu Dai, Ziqiang Shao, Xiaonan Huang
To develop healable hydrogels with excellent mechanical properties is still a challenge topic. In this study, a novel class of physically crosslinked polyacrylamide based nanocomposite hydrogels reinforced with cellulose nanofibers (CNF) were fabricated using radical polymerization, followed by further strengthening through ferric ions via strong ionic coordination interactions between Fe3+ and carboxyls on CNF surfaces. Then the obtained gels were characterized by FTIR, tensile and compressive measurements as well as healing experiments...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29773377/mechanically-viscoelastic-nanoreinforced-hybrid-hydrogels-composed-of-polyacrylamide-sodium-carboxymethylcellulose-graphene-oxide-and-cellulose-nanocrystals
#4
Anuj Kumar, Kummara Madhusudana Rao, Sung Soo Han
Polyacrylamide-sodium carboxymethylcellulose (PMC) hybrid hydrogels reinforced with graphene oxide (GO) and/or cellulose nanocrystals (CNCs) were prepared via in situ free-radical polymerization. In this work, GO nanosheets were freshly synthesized by modified Hummer's method alongwith the aqueous suspension of CNCs by acid-hydrolysis. In addition, the effect of GO content (1.5 wt%) and CNCs (from 2.5 wt% to 10.0 wt%) was investigated in these quaternary hydrogels. The results showed good pseudo-plastic behavior, self-healing ability, mechanical performance, and shape-recovery behavior of the hybrid hydrogels reinforced with GO and CNCs content...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29772841/the-effect-of-human-mesenchymal-stem-cells-derived-from-wharton-s-jelly-in-spinal-cord-injury-treatment-is-dose-dependent-and-can-be-facilitated-by-repeated-application
#5
Petr Krupa, Irena Vackova, Jiri Ruzicka, Kristyna Zaviskova, Jana Dubisova, Zuzana Koci, Karolina Turnovcova, Lucia Machova Urdzikova, Sarka Kubinova, Svatopluk Rehak, Pavla Jendelova
Human mesenchymal stem cells derived from Wharton's jelly (WJ-MSCs) were used for the treatment of the ischemic-compression model of spinal cord injury in rats. To assess the effectivity of the treatment, different dosages (0.5 or 1.5 million cells) and repeated applications were compared. Cells or saline were applied intrathecally by lumbar puncture for one week only, or in three consecutive weeks after injury. Rats were assessed for locomotor skills (BBB, rotarod, flat beam) for 9 weeks. Spinal cord tissue was morphometrically analyzed for axonal sprouting, sparing of gray and white matter and astrogliosis...
May 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29771751/utility-of-optical-coherence-tomography-in-the-evaluation-of-sellar-and-parasellar-mass-lesions
#6
Omar Al-Louzi, Sashank Prasad, Robert M Mallery
PURPOSE OF REVIEW: Anterior visual pathway compression is a common feature of sellar region masses. We review the visual pathway neuroanatomy pertaining to sellar and parasellar lesions and describe recent advances in optical coherence tomography (OCT) imaging that have provided a novel quantitative perspective in the evaluation and management of such patients. RECENT FINDINGS: Ultrastructural measurements of optic nerve integrity using OCT, namely peripapillary retinal nerve fiber layer (pRNFL) and the ganglion cell and inner plexiform layer (GCIPL) thicknesses, have been shown to correlate with visual acuity and visual field deficits on perimetry in patients with compressive sellar region masses...
May 15, 2018: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/29764556/-extra-longtime-continuous-chest-compression-to-rescue-cardiopulmonary-arrest-a-case-report-and-the-literature-review
#7
Yan Zhang, Tianxue Yue, Kexin Sun, Jiang Wang, Ruiwu Zhu
The new cardiopulmonary resuscitation (CPR) guideline emphasize the importance of chest compression, which was considered as the first step to CPR. The duration for CPR is usually limited to 30 minutes. With the development of new technology and evidence-based medicine, the success of extra longtime CPR has become possible, which is of great significance to some patients with cardiac arrest (CA), but the time limit has not been determined. On February 23rd in 2016, a 76-year-old female patient with respiratory and cardiac arrest who was on the third day after transurethral resection of bladder tumor (TUR-BT) was admitted to the intensive care unit of the General Hospital of Fushun Mining Bureau...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29764528/symptomatic-myocardial-bridging-a-frequently-occurring-coronary-variation-can-cause-severe-myocardial-ischaemia-in-affected-children-with-underlying-cardiac-conditions
#8
Alexandra Kiess, Marcel Vollroth, Farhad Bakhtiary, Hiroshi Seki, Martin Kostelka, Milan Djukic, Ingo Daehnert, Robert Wagner
Myocardial bridging is a congenital coronary artery anomaly in which the coronary artery has a partly "tunnelled" intramyocardial course. This tunnelling leads to compression of the affected vessel segment during ventricular systole. It is considered to be a benign variation of the norm in about 25% of the population caused by an aberrancy of embryologic coronary development. The bridging is also thought to cause severe cardiac conditions in a few of those affected. The series of six young patients presented here is the largest series so far to report on symptomatic myocardial bridging in children with different underlying heart diseases...
May 16, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29761414/spatially-resolved-kinetics-of-skeletal-muscle-exercise-response-and-recovery-with-multiple-echo-diffusion-tensor-imaging-mediti-a-feasibility-study
#9
E E Sigmund, S H Baete, K Patel, D Wang, D Stoffel, R Otazo, P Parasoglou, J Bencardino
OBJECTIVES: We describe measurement of skeletal muscle kinetics with multiple echo diffusion tensor imaging (MEDITI). This approach allows characterization of the microstructural dynamics in healthy and pathologic muscle. MATERIALS AND METHODS: In a Siemens 3-T Skyra scanner, MEDITI was used to collect dynamic DTI with a combination of rapid diffusion encoding, radial imaging, and compressed sensing reconstruction in a multi-compartment agarose gel rotation phantom and within in vivo calf muscle...
May 14, 2018: Magma
https://www.readbyqxmd.com/read/29758507/recovery-practices-in-division-1-collegiate-athletes-in-north-america
#10
Andrew Murray, Hugh Fullagar, Anthony P Turner, John Sproule
OBJECTIVES: Establish current practice and attitudes towards recovery in a group of Division-1 Collegiate athletes from North America. DESIGN: A 16-item questionnaire was administered via custom software in an electronic format. PARTICIPANTS: 152 student athletes from a Division-1 Collegiate school across 3 sports (Basketball, American Football, Soccer). MAIN OUTCOME MEASURES: The approaches and attitudes to recovery in both training and competition...
May 8, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29757278/a-microbiomechanical-system-for-studying-varicosity-formation-and-recovery-in-central-neuron-axons
#11
Dustin Servello, Yuanzheng Gu, Chen Gu
Axonal varicosities are enlarged structures along the shafts of axons with a high degree of heterogeneity. They are present not only in brains with neurodegenerative diseases or injuries, but also in the normal brain. Here, we describe a newly-established micromechanical system to rapidly, reliably, and reversibly induce axonal varicosities, allowing us to understand the mechanisms governing varicosity formation and heterogeneous protein composition. This system represents a novel means to evaluate the effects of compression and shear stress on different subcellular compartments of neurons, different from other in vitro systems that mainly focus on the effect of stretching...
April 30, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29755607/risk-factors-for-the-development-of-nerve-palsy-following-primary-total-hip-arthroplasty
#12
Shunsuke Kawano, Motoki Sonohata, Masaru Kitajima, Masaaki Mawatari
Background: Nerve palsy following total hip arthroplasty (THA) is a complication that worsens the functional prognosis. The present study analyzed the risk factors of nerve palsy following THA. Methods: The subjects of this study included 6,123 cases in which primary THA was performed under spinal anesthesia with cementless implants used in the posterolateral approach. Results: Fourteen cases (0.22%) developed nerve palsy following THA, all of which involved palsy of the entire peroneal nerve region...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29755363/an-evidence-based-approach-for-choosing-post-exercise-recovery-techniques-to-reduce-markers-of-muscle-damage-soreness-fatigue-and-inflammation-a-systematic-review-with-meta-analysis
#13
Olivier Dupuy, Wafa Douzi, Dimitri Theurot, Laurent Bosquet, Benoit Dugué
Introduction: The aim of the present work was to perform a meta-analysis evaluating the impact of recovery techniques on delayed onset muscle soreness (DOMS), perceived fatigue, muscle damage, and inflammatory markers after physical exercise. Method: Three databases including PubMed, Embase , and Web-of-Science were searched using the following terms: ("recovery" or "active recovery" or "cooling" or "massage" or "compression garment" or "electrostimulation" or "stretching" or "immersion" or "cryotherapy") and ("DOMS" or "perceived fatigue" or "CK" or "CRP" or "IL-6") and ("after exercise" or "post-exercise") for randomized controlled trials, crossover trials, and repeated-measure studies...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29752219/immediate-weightbearing-after-first-metatarsophalangeal-joint-arthrodesis-with-screw-and-locking-plate-fixation-a-short-term-review
#14
Kyle W Abben, Matthew D Sorensen, Brett J Waverly
Historically, the postoperative protocol for patients undergoing first metatarsophalangeal joint arthrodesis has included 6 weeks of non-weightbearing, followed by protected weightbearing in a below-the-knee cast boot or postoperative shoe. This prolonged period of non-weightbearing predisposes the patient to disuse atrophy, osteopenia, deep vein thrombosis risk, and, overall, a prolonged time to recovery. The present study reports a retrospective review of a patient cohort that underwent first metatarsophalangeal joint fusion with immediate full weightbearing postoperatively...
May 8, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29751769/repeated-injections-of-human-umbilical-cord-blood-derived-mesenchymal-stem-cells-significantly-promotes-functional-recovery-in-rabbits-with-spinal-cord-injury-of-two-noncontinuous-segments
#15
Chaohua Yang, Gaoju Wang, Fenfen Ma, Baoqing Yu, Fancheng Chen, Jin Yang, Jianjun Feng, Qing Wang
BACKGROUND: Spinal cord injuries (SCIs) are sustained by an increasing number of patients each year worldwide. The treatment of SCIs has long been a hard nut to crack for doctors around the world. Mesenchymal stem cells (MSCs) have shown benefits for the repair of SCI and recovery of function. Our present study aims to investigate the effects of intravenously infused human umbilical cord blood-derived MSCs (hUCB-MSCs) on functional recovery after subacute spinal cord compression injury of two noncontinuous segments...
May 11, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29749919/results-of-reoperation-for-failed-ulnar-nerve-surgery-at-the-elbow-a-systematic-review-and-meta-analysis
#16
Tinatin Natroshvili, Erik T Walbeehm, Nens van Alfen, Ronald H M A Bartels
OBJECTIVE The clinical results of reoperation for recurrent or persistent ulnar nerve compression at the elbow have not been clearly determined. The aim of this review was to determine overall improvement, residual pain, and sensory and motor deficits following reoperation regardless of the type of primary surgery performed for this condition. METHODS In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, a systematic review and meta-analysis of studies was performed...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29749479/effect-of-combined-chondroitinase-abc-and-hyperbaric-oxygen-therapy-in-a-rat-model-of-spinal-cord-injury
#17
Xiaoyang Liu, Jiefeng Wang, Guangkuo Li, Honglin Lv
The present study aimed to investigate the effect of combined hyperbaric oxygen (HBO) and chondroitinase ABC (ChABC) enzyme therapy in a rat model of spinal cord injury (SCI) and to explore the underlying mechanisms. A total of 48 healthy male Wistar rats were randomly divided into six groups: Sham, SCI, vehicle, HBO, ChABC enzyme and HBO + ChABC. Excluding the sham group, SCI was established in rats by a clip compression injury and rats subsequently received HBO treatment for 2 weeks with or without an intraspinal injection of 0...
April 26, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29747025/facile-recycling-of-escherichia-coli-and-saccharomyces-cerevisiae-cells-from-suspensions-using-magnetic-modification-method-and-mechanism-analysis
#18
Jun Zhao, Meng Lin, Guo Chen
Cell recycling for catalysis using whole cell significantly reduced the cost of the catalyst, therefore a simple and rapid method for cell recovery from the reaction system was very important. A facile method for cell modification and recycling was developed by simply mixing the carboxyl-functionalized Fe3 O4 magnetic nanoparticles (MNPs) and cell suspension. The mode microbes Escherichia coli and Saccharomyces cerevisiae were easily modified by directly adsorbing MNPs on their surface, which facilitated rapid separation and recycling of cells from suspensions with the aid of magnetic field...
May 3, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29746986/efficacy-and-safety-of-mechanical-versus-manual-compression-in-cardiac-arrest-a-bayesian-network-meta-analysis
#19
REVIEW
Safi U Khan, Ahmad N Lone, Swapna Talluri, Muhammad Z Khan, Muhammad U Khan, Edo Kaluski
AIM: To compare relative efficacy and safety of mechanical compression devices (AutoPulse and LUCAS) with manual compression in patients with cardiac arrest undergoing cardiopulmonary resuscitation (CPR). METHODS: For this Bayesian network meta-analysis, seven randomized controlled trials (RCTs) were selected using PubMed/Medline, EMBASE, and CENTRAL (Inception- 31 October 2017). For all the outcomes, median estimate of odds ratio (OR) from the posterior distribution with corresponding 95% credible interval (Cr I) was calculated...
May 7, 2018: Resuscitation
https://www.readbyqxmd.com/read/29745256/salvage-of-cervical-motor-radiculopathy-using-peripheral-nerve-transfer-reconstruction
#20
Fardad T Afshari, Taushaba Hossain, Caroline Miller, Dominic M Power
PURPOSE: Motor nerve transfer surgery involves re-innervation of important distal muscles using either an expendable motor branch or a fascicle from an adjacent functioning nerve. This technique is established as part of the reconstructive algorithm for traumatic brachial plexus injuries. The reproducible outcomes of motor nerve transfer surgery have resulted in exploration of the application of this technique to other paralysing conditions. The objective of this study is to report feasibility and increase awareness about nerve transfer as a method of improving upper limb function in patients with cervical motor radiculopathy of different aetiology...
May 10, 2018: British Journal of Neurosurgery
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