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https://www.readbyqxmd.com/read/29343699/collagen-binding-hepatocyte-growth-factor-hgf-alone-or-with-a-gelatin-furfurylamine-hydrogel-enhances-functional-recovery-in-mice-after-spinal-cord-injury
#1
Kentaro Yamane, Tetsuro Mazaki, Yasuyuki Shiozaki, Aki Yoshida, Kensuke Shinohara, Mariko Nakamura, Yasuhiro Yoshida, Di Zhou, Takashi Kitajima, Masato Tanaka, Yoshihiro Ito, Toshifumi Ozaki, Akihiro Matsukawa
The treatment of spinal cord injury (SCI) is currently a significant challenge. Hepatocyte growth factor (HGF) is a multipotent neurotrophic and neuroregenerative factor that can be beneficial for the treatment of SCI. However, immobilized HGF targeted to extracellular matrix may be more effective than diffusible, unmodified HGF. In this study, we evaluated the neurorestorative effects of an engineered HGF with a collagen biding domain (CBD-HGF). CBD-HGF remained in the spinal cord for 7 days after a single administration, while unmodified HGF was barely seen at 1 day...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29332032/value-of-conventional-mri-and-diffusion-tensor-imaging-parameters-in-predicting-surgical-outcome-in-patients-with-degenerative-cervical-myelopathy
#2
Canghai Shen, Haiwei Xu, Baoshan Xu, Xiaoguang Zhang, Xiaofeng Li, Qiang Yang, Xinlong Ma
BACKGROUND: In addition to conventional magnetic resonance imaging (cMRI), diffusion tensor imaging (DTI) has been investigated as a potential diagnostic and prognostic tool for patients with degenerative cervical myelopathy (DCM). OBJECTIVE: To assess the efficacy of cMRI and DTI parameters in prediction of surgical outcome in DCM patients. METHODS: One hundred and forty-two patients with DCM who underwent presurgical cMRI and DTI of the cervical spine were included...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29328307/channel-estimation-for-wideband-underwater-visible-light-communication-a-compressive-sensing-perspective
#3
Xu Ma, Fang Yang, Sicong Liu, Jian Song
With the rapid development of light emitting diode (LED), visible light communication (VLC) becomes an important technique for information transmission including underwater applications. However, accurate channel estimation for underwater VLC is still challenging due to the complex environment of the underwater VLC channel. In this paper, by utilizing a proper approximation, where the channel attenuation is linear with the frequency, a new compressive sensing (CS) based channel estimation approach is proposed...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29306802/smoothing-inertial-projection-neural-network-for-minimization-lp-q-in-sparse-signal-reconstruction
#4
You Zhao, Xing He, Tingwen Huang, Junjian Huang
In this paper, we investigate a more general sparse signal recovery minimization model and a smoothing neural network optimal method for compress sensing problem, where the objective function is a Lp-q minimization model which includes nonsmooth, nonconvex, and non-Lipschitz quasi-norm Lp norms 1≥p>0 and nonsmooth Lq norms 2≥p>1, and its feasible set is a closed convex subset of Rn. Firstly, under the restricted isometry property (RIP) condition, the uniqueness of solution for the minimization model with a given sparsity s is obtained through the theoretical analysis...
December 20, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29304485/four-dimensional-data-coupled-to-alternating-weighted-residue-constraint-quadrilinear-decomposition-model-applied-to-environmental-analysis-determination-of-polycyclic-aromatic-hydrocarbons
#5
Tingting Liu, Ling Zhang, Shutao Wang, Yaoyao Cui, Yutian Wang, Lingfei Liu, Zhe Yang
Qualitative and quantitative analysis of polycyclic aromatic hydrocarbons (PAHs) was carried out by three-dimensional fluorescence spectroscopy combining with Alternating Weighted Residue Constraint Quadrilinear Decomposition (AWRCQLD). The experimental subjects were acenaphthene (ANA) and naphthalene (NAP). Firstly, in order to solve the redundant information of the three-dimensional fluorescence spectral data, the wavelet transform was used to compress data in preprocessing. Then, the four-dimensional data was constructed by using the excitation-emission fluorescence spectra of different concentration PAHs...
December 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29303466/delayed-neurological-deterioration-following-atlantoaxial-facet-joint-distraction-and-fixation-in-a-patient-with-chiari-malformation-type-i
#6
Tatsushi Inoue, Natsuki Hattori, Tsukasa Ganaha, Tadashi Kumai, Shinichiro Tateyama, Yuichi Hirose
Chiari malformation type I (CM-I) is typically treated with foramen magnum decompression. However, a recent study proposed a new technique for patients with CM-I, wherein only short atlantoaxial joint fusion and distraction is applied. Posterior fusion with or without atlantoaxial distraction is a potential option for patients with CM-I associated with basilar invagination or complex anomalous bony craniovertebral junction pathology, since this procedure allows clinicians to avoid using the technically demanding transoral approach in which some or all of the odontoid tip is invisible...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29303386/visual-prognosis-in-compressive-optic-neuropathy-secondary-to-sphenoid-sinus-mucocele-a-systematic-review
#7
Emily Li, Martha A Howard, Eugenia M Vining, Richard D Becker, Jonathan Silbert, Robert L Lesser
Sphenoid sinus mucoceles (SSMs) are rare, benign lesions that can expand, often presenting with ocular symptoms-decreased vision, diplopia, visual field defects, proptosis, and external ophthalmoplegia. Reported cases are few, visual compromise varies, and factors affecting visual prognosis are poorly characterized. We investigate whether prompt surgical intervention (within 2 weeks of visual symptom onset) affects best-corrected visual acuity (BCVA) regained in patients with vision loss secondary to compressive SSM...
January 5, 2018: Orbit
https://www.readbyqxmd.com/read/29301602/progress-in-intraoperative-neurophysiological-monitoring-for-the-surgical-treatment-of-thoracic-spinal-stenosis
#8
Yong-Sheng Liu, Yu Zhao
Thoracic spinal stenosis (TSS) is a group of clinical syndromes caused by thoracic spinal cord compression, which always results in severe clinical complications. The incidence of TSS is relatively low compared with lumbar spinal stenosis, while the incidence of spinal cord injury during thoracic decompression is relatively high. The reported incidence of neurological deficits after thoracic decompression reached 13.9%. Intraoperative neurophysiological monitoring (IONM) can timely provide information regarding the function status of the spinal cord, and help surgeons with appropriate performance during operation...
December 30, 2017: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/29291538/tension-pneumoperitoneum-after-bystander-cardiopulmonary-resuscitation-a-case-report
#9
Sherry Johnson, Jessica McCracken, Fadi Baidoun
INTRODUCTION: Abdominal visceral injuries after cardiopulmonary resuscitation (CPR) are infrequent though can be significant complications of CPR requiring invasive interventions. We present a case of a gastric perforation as a result of bystander CPR. This resulted in tension pneumoperitoneum necessitating abdominal decompression prior to laparotomy and repair. PRESENTATION OF CASE: 37-year-old female complained of abdominal pain and distension after return of spontaneous circulation from successful CPR following a drug overdose and cardiopulmonary arrest...
December 12, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29284846/comparison-of-the-intravenous-and-epidural-administration-of-tumor-necrosis-factor-alpha-antagonists-in-an-experimental-rat-pain-model
#10
Serbülent Gökhan Beyaz, Mustafa Erkan İnanmaz, Tolga Ergönenç, Onur Palabıyık, Yakup Tomak, Ayça Taş Tuna
Introduction: Inflammatory cytokines secreted from the nucleus pulposus are thought to lead to lumbar nerve root compression-like symptoms. Tumor necrosis factor-alpha (TNF-α), an inflammatory cytokine, likely plays an important role in lumbar disc hernia-related leg pain. In this experimental study, we compared the effectiveness of TNF-α antagonists administered through the intravenous or epidural route in lumbar spine pathologies. Materials and Methods: After ethics committee approval had been obtained, 24 Sprague Dawley male rats aged 70-90 days and weighing 250-300 g each were allocated to four groups...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29279755/delayed-neurological-deficits-after-osteoporotic-vertebral-fractures-clinical-outcomes-after-surgery
#11
Yip-Kan Yeung, Sheung-Tung Ho
Study Design: Retrospective cohort. Purpose: To review the clinical presentation of operated patients with delayed neurological deficits after osteoporotic vertebral fractures (OVFs). Overview of Literature: Delayed neurological deficits can occur from 1 week to 5.7 months after OVFs. Baba has reported 78% good-to-excellent improvement (i.e., ≥50%) after 20 posterior (Cotrel-Dubousset) and 7 anterior (Kaneda in 4, Zielke ventral derotational spondylodesis in 2, and un-instrumented anterior fusion in 1) fusions...
December 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29276541/fully-recoverable-rigid-shape-memory-foam-based-on-copper-catalyzed-azide-alkyne-cycloaddition-cuaac-using-a-salt-leaching-technique
#12
Abeer A Alzahrani, Mohand Saed, Christopher M Yakacki, Han Byul Song, Nancy Sowan, Joshua J Walston, Parag K Shah, Matthew K McBride, Jeffrey W Stansbury, Christopher N Bowman
This study is the first to employ the use of the copper-catalyzed azide-alkyne cycloaddition (CuAAC) polymerization to form a tough and stiff, porous material from a well-defined network possessing a high glass transition temperature. The effect of the network linkages formed as a product of the CuAAC reaction, i.e., the triazoles, on the mechanical behavior at high strain was evaluated by comparing the CuAAC foam to an epoxy-amine-based foam, which consisted of monomers with similar backbone structures and mechanical properties (i...
January 7, 2018: Polymer Chemistry
https://www.readbyqxmd.com/read/29275109/superelastic-and-superhydrophobic-bacterial-cellulose-silica-aerogels-with-hierarchical-cellular-structure-for-oil-absorption-and-recovery
#13
Jian He, Hangyuan Zhao, Xiaolei Li, Dong Su, Fengrui Zhang, Huiming Ji, Rui Liu
Bacterial cellulose aerogels/silica aerogels (BCAs/SAs) are prepared using three-dimensional self-assembled BC skeleton as reinforcement and methyltriethoxysilane derived silica aerogels as filler through vacuum infiltration and freeze drying. The BCAs/SAs possess a hierarchical cellular structure giving them superelasticity and recyclable compressibility. The BCAs/SAs can bear a compressive strain up to 80% and recover their original shapes after the release of the stress. The BCAs/SAs exhibit super-hydrophobicity with a contact angle of 152° and super-oleophilicity resulting from the methyl groups on the surface of silica aerogel filler...
December 18, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29274478/a-compound-scaffold-with-uniform-longitudinally-oriented-guidance-cues-and-a-porous-sheath-promotes-peripheral-nerve-regeneration-in-vivo
#14
Liangliang Huang, Lei Zhu, Xiaowei Shi, Bing Xia, Zhongyang Liu, Shu Zhu, Yafeng Yang, Teng Ma, Pengzhen Cheng, Kai Luo, Jinghui Huang, Zhuojing Luo
Scaffolds with inner fillers that convey directional guidance cues represent promising candidates for nerve repair. However, incorrect positioning or non-uniform distribution of intraluminal fillers might result in regeneration failure. In addition, proper porosity (to enhance nutrient and oxygen exchange but prevent fibroblast infiltration) and mechanical properties (to ensure fixation and to protect regenerating axons from compression) of the outer sheath are also highly important for constructing advanced nerve scaffolds...
December 20, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29273659/pted-study-design-of-a-non-inferiority-randomised-controlled-trial-to-compare-the-effectiveness-and-cost-effectiveness-of-percutaneous-transforaminal-endoscopic-discectomy-pted-versus-open-microdiscectomy-for-patients-with-a-symptomatic-lumbar-disc-herniation
#15
Ankie Seiger, Pravesh S Gadjradj, Biswadjiet S Harhangi, Job Lc van Susante, Wilco C Peul, Maurits W van Tulder, Michiel R de Boer, Sidney M Rubinstein
INTRODUCTION: Lumbosacral radicular syndrome is often caused by a disc herniation. The standard surgical technique to remove a disc herniation is open microdiscectomy. An alternative technique is percutaneous transforaminal endoscopic discectomy (PTED), which is less invasive. In the Netherlands, PTED is not currently considered as standard care, and therefore not reimbursed within public health insurance. A pragmatic, multicentre, non-inferiority, randomised controlled trial has been designed to determine the effectiveness and cost-effectiveness of PTED versus open microdiscectomy for the treatment of lumbar disc herniation...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29273609/bone-marrow-edema-associated-with-everolimus
#16
Rachel Lebovic McDevitt, Chelsey Quinlan, Katie Hersberger, Vaibhav Sahai
PURPOSE: The case of a patient who experienced bone marrow edema and pain in both feet and a compression fracture of one heel bone after several months of everolimus use is reported. SUMMARY: A 62-year-old woman with a grade 1 metastatic pancreatic neuroendocrine tumor (pNET) developed bilateral lower extremity edema and pain approximately 4 months after initiation of treatment with everolimus, an inhibitor of mammalian (or mechanistic) target of rapamycin (mTOR)...
January 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29259148/successful-recovery-from-spontaneous-spinal-epidural-hematoma-in-a-patient-undergoing-hemodialysis
#17
Arata Hibi, Takahisa Kasugai, Keisuke Kamiya, Keisuke Kamiya, Satoru Kominato, Chiharu Ito, Toshiyuki Miura, Katsushi Koyama
BACKGROUND Spontaneous spinal epidural hematoma (SSEH) occurs in the spinal epidural space in the absence of traumatic or iatrogenic causes, and is considered to be a neurological emergency, as spinal cord compression may lead to neurological deficit. Prompt diagnosis of SSEH can be difficult due to the variety of presenting symptoms, which may resemble those of stroke. Patients who undergo hemodialysis (HD) are at risk of bleeding due to anticoagulation during dialysis and uremia. However, SSEH in HD patients undergoing HD has rarely been reported...
December 20, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29250478/an-unusual-complication-of-congenital-diaphragmatic-hernia
#18
E Tian Tan, Keren Sloan, Kokila Lakhoo
A term newborn was referred to our unit with a postnatal diagnosis of a right-sided congenital diaphragmatic hernia (CDH). She was managed with high-frequency oscillatory ventilation, inotropic support, and nitric oxide, with planned surgical repair when she was medically optimized. On day 6 of life, there was an acute deterioration causing difficulty maintaining adequate ventilation and the infant requiring increasing analgesia and paralysis, especially during abdominal examination. A repeat X-ray showed distended bowel loops in the right hemithorax when compared with previous films raising suspicion of bowel obstruction...
January 2017: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/29234284/the-efficacy-of-wrestling-style-compression-suits-to-improve-maximum-isometric-force-and-movement-velocity-in-well-trained-male-rugby-athletes
#19
Daniel T McMaster, Christopher M Beaven, Brad Mayo, Nicholas Gill, Kim Hébert-Losier
Purpose: The prevalence of compression garment (CG) use is increasing with athletes striving to take advantage of the purported benefits to recovery and performance. Here, we investigated the effect of CG on muscle force and movement velocity performance in athletes. Methods: Ten well-trained male rugby athletes wore a wrestling-style CG suit applying 13-31 mmHg of compressive pressure during a training circuit in a repeated-measures crossover design. Force and velocity data were collected during a 5-s isometric mid-thigh pull (IMTP) and repeated countermovement jump (CMJ), respectively; and time to complete a 5-m horizontal loaded sled push was also measured...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29225395/review-water-recovery-from-brines-and-salt-saturated-solutions-operability-and-thermodynamic-efficiency-considerations-for-desalination-technologies
#20
Leland M Vane
BACKGROUND: When water is recovered from a saline source, a brine concentrate stream is produced. Management of the brine stream can be problematic, particularly in inland regions. An alternative to brine disposal is recovery of water and possibly salts from the concentrate. RESULTS: This review provides an overview of desalination technologies and discusses the thermodynamic efficiencies and operational issues associated with the various technologies particularly with regard to high salinity streams...
March 8, 2017: Journal of Chemical Technology and Biotechnology
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