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https://www.readbyqxmd.com/read/28230791/the-temporal-pattern-flux-and-function-of-autophagy-in-spinal-cord-injury
#1
REVIEW
Kailiang Zhou, Charles A Sansur, Huazi Xu, Xiaofeng Jia
Previous studies have indicated that autophagy plays a critical role in spinal cord injury (SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord injury (IRSCI). However, while the understanding of mechanisms underlying autophagy in SCI has progressed, there remain several controversial points: (1) temporal pattern results of autophagic activation after SCI are not consistent across studies; (2) effect of accumulation of autophagosomes due to the blockade or enhancement of autophagic flux is uncertain; (3) overall effect of enhanced autophagy remains undefined, with both beneficial and detrimental outcomes reported in SCI literature...
February 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28226532/sampling-and-recovery-of-mri-data-using-low-rank-tensor-models
#2
Daniel Banco, Shuchin Aeron, W Scott Hoge, Daniel Banco, Shuchin Aeron, W Scott Hoge, Shuchin Aeron, Daniel Banco, W Scott Hoge
In this paper we investigate the utility of several low-rank models for recovery of Magnetic Resonance Imaging (MRI) data from limited sampling in the k - t space for dynamic imaging. In particular, for 3D temporal (2D space + time) MRI data we employ several tensor factorization techniques and assess the degree of dimensionality reduction, or compressibility, that can be obtained. This algebraic approach is more data adaptive, in contrast to existing compressed sensing (CS) based methods that exploit sparsity in a transform domain, such as wavelets or total variation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225364/preoperative-risk-factors-of-c5-nerve-root-palsy-after-laminectomy-and-fusion-in-patients-with-cervical-myelopathy-analysis-of-70-consecutive-patients
#3
Kyung-Soo Suk, Kyung-Chung Kang, Hak-Sun Kim, Seong-Hwan Moon, Hwan-Mo Lee, Jung-Ho Seo, Sung-Min Kim, Sung-Yub Jin, Pierre Mella
STUDY DESIGN: A retrospective study. OBJECTIVE: To identify preoperative risk factors causing cervical fifth nerve root palsy (C5 palsy) after laminectomy and fusion (LF). SUMMARY OF BACKGROUND DATA: It is well known that postoperative C5 palsy is not rare after cervical surgery. Although there remains controversy, C5 palsy is considered to be more common in patients who had LF than in those who had laminoplasty. However, the reason for the higher incidence of C5 palsy in patients with LF has been poorly understood...
February 20, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28216760/vanishing-bone-disease-of-chest-wall-and-spine-with-kyphoscoliosis-and-neurological-deficit-a-case-report-and-review-of-literature
#4
Sudhir Kumar Srivastava, Rishi Anil Aggarwal, Pradip Sharad Nemade, Sunil Krishna Bhoale
Vanishing bone disease is an extremely rare disorder of unknown etiology characterized by idiopathic osteolysis of bone. We describe a case of vanishing bone disease of chest wall and spine with kyphoscoliosis and neurological deficit. A 17-year-old male presented with gradually progressive deformity of back and dorsal compressive myelopathy with nonambulatory power in lower limbs. Radiographs revealed absent 4(th)-7(th) ribs on the right side with dorsal kyphoscoliosis and severe canal narrowing at the apex...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28214787/sparse-and-dense-hybrid-representation-via-subspace-modeling-for-dynamic-mri
#5
Qiegen Liu, Shanshan Wang, Dong Liang
Recent theoretical results on compressed sensing and low-rank matrix recovery have inspired significant interest in joint sparse and low rank modeling of dynamic magnetic resonance imaging (dMRI). Existing approaches usually describe these two respective prior information with different formulations. In this paper, we present a novel sparse and dense hybrid representation (SDR) model which describes the sparse plus low rank properties by a unified way. More specifically, under the learned dictionary consisting of temporal basis functions, SDR models the spatial coefficients in two subspaces with Laplacian and Gaussian prior distributions, respectively...
February 5, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28213166/influence-of-clamping-stress-and-duration-on-the-trauma-of-liver-tissue-during-surgery-operation
#6
Jin Wang, Qing-Yuan Yu, Wei Li, Bing-Rui Wang, Zhong-Rong Zhou
BACKGROUND: Tissue grasping damage often occurs in minimally invasive surgery, which would increase the postoperative recovery time and the risk of surgical complications. The purpose of this study was to evaluate the relationship between liver tissue trauma and compression stress magnitude and duration during tissue clamping operation. METHODS: The clamping experiments of liver tissues in vivo were conducted by using a universal soft tissue mechanical testing machine under different clamping stress magnitudes and durations...
February 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28203505/bilateral-sciatic-neuropathy-after-an-autologous-breast-reconstruction-in-a-massive-weight-loss-patient
#7
Ramy Abdel-Naby, Michael Ablavsky, Aleksandr Shteynberg
Perioperative compression neuropathy is a known potential complication of prolonged surgical procedures. Sciatic postoperative neuropathy has rarely been reported. We present a 34-year-old woman who underwent right breast reconstruction with supercharged (venous anastomosis) transverse rectus abdominis flap and developed bilateral sciatic compression neuropathy. Her history was remarkable for sleeve gastrectomy 2 years earlier resulting in 105 pound weight loss 1 year before breast reconstruction. During the procedure, the patient was in the supine position for 8 hours and in the semirecumbent position for an additional 2 hours with the torso flexed at 30 degrees and knees flexed at approximately 45 degrees in addition to standard padding...
January 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28197789/surgical-outcome-for-severe-cubital-tunnel-syndrome-in-patients-aged-70%C3%A2-years-a-mean-follow-up-of-4-5%C3%A2-years
#8
Jinsong Tong, Bin Xu, Zhen Dong, Chenggang Zhang, Yudong Gu
BACKGROUND: Surgical outcomes for cubital tunnel syndrome have been reported to be satisfactory, but could be compromised by advanced age and severe nerve compression. We aim to evaluate the prognosis of severe cubital tunnel syndrome in patients aged >70 years. METHODS: This retrospective study included 25 patients (26 extremities, all McGowan grade III, age >70 years); 21 underwent subcutaneous transposition and 5 in situ decompression. Postoperative follow-up lasted >2 years...
February 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28196300/omnidirectional-shape-memory-effect-via-lyophilization-of-peg-hydrogels
#9
Di Chen, Xuhui Xia, Tuck W Wong, Hao Bai, Marc Behl, Qian Zhao, Andreas Lendlein, Tao Xie
Device applications of shape memory polymers demand diverse shape changing geometries, which are currently limited to non-omnidirectional movement. This restriction originates from traditional thermomechanical programming methods such as uniaxial, biaxial stretching, bending, or compression. A solvent-modulated programming method is reported to achieve an omnidirectional shape memory behavior. The method utilizes freeze drying of hydrogels of polyethylene glycol networks with a melting transition temperature around 50 °C in their dry state...
February 14, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28195832/four-dimensional-printing-hierarchy-scaffolds-with-highly-biocompatible-smart-polymers-for-tissue-engineering-applications
#10
Shida Miao, Wei Zhu, Nathan J Castro, Jinsong Leng, Lijie Grace Zhang
The objective of this study was to four-dimensional (4D) print novel biomimetic gradient tissue scaffolds with highly biocompatible naturally derived smart polymers. The term "4D printing" refers to the inherent smart shape transformation of fabricated constructs when implanted minimally invasively for seamless and dynamic integration. For this purpose, a series of novel shape memory polymers with excellent biocompatibility and tunable shape changing effects were synthesized and cured in the presence of three-dimensional printed sacrificial molds, which were subsequently dissolved to create controllable and graded porosity within the scaffold...
October 2016: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28193282/preoperative-embolization-in-patients-with-metastatic-spinal-cord-compression-mandatory-or-optional
#11
Chul Gie Hong, Jae Hwan Cho, Dae Chul Suh, Chang Ju Hwang, Dong-Ho Lee, Choon Sung Lee
BACKGROUND: The contribution of preoperative embolization in reducing intraoperative blood loss and its clinical importance are unclear. So, we aimed to compare the perioperative clinical outcomes based on whether preoperative embolization was performed and assess the role and safety of preoperative embolization in metastatic spinal cord compression (MSCC) patients. METHODS: We enrolled 52 patients (men, 37; women, 15) who underwent palliative decompression for MSCC...
February 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28192386/spectrum-of-magnetic-resonance-imaging-features-in-unilateral-optic-tract-dysfunction
#12
Kristopher M Kowal, Francisco F Rivas Rodriguez, Ashok Srinivasan, Jonathan D Trobe
BACKGROUND: Optic tract dysfunction may be the predominant or only clinical manifestation of an intracranial disorder including mass legion, ischemic infarct, inflammatory disease, and trauma. Documentation of the neuroimaging features of these lesions is limited to reports mostly published before the availability of MRI. This study was undertaken to document the spectrum of MRI features in patients presenting with optic tract dysfunction. METHODS: A retrospective study from 2004 to 2015 at a single tertiary care neuro-ophthalmology service of 24 patients who had unilateral optic tract dysfunction defined by a homonymous hemianopia and a relative afferent pupil defect that could not be attributed to optic neuropathy or retinopathy...
March 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28192348/concentration-driven-models-revisited-towards-a-unified-framework-to-model-settling-tanks-in-water-resource-recovery-facilities
#13
Elena Torfs, M Carmen Martí, Florent Locatelli, Sophie Balemans, Raimund Bürger, Stefan Diehl, Julien Laurent, Peter A Vanrolleghem, Pierre François, Ingmar Nopens
A new perspective on the modelling of settling behaviour in water resource recovery facilities is introduced. The ultimate goal is to describe in a unified way the processes taking place both in primary settling tanks (PSTs) and secondary settling tanks (SSTs) for a more detailed operation and control. First, experimental evidence is provided, pointing out distributed particle properties (such as size, shape, density, porosity, and flocculation state) as an important common source of distributed settling behaviour in different settling unit processes and throughout different settling regimes (discrete, hindered and compression settling)...
February 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28187894/improving-recovery-of-ecg-signal-with-deterministic-guarantees-using-split-signal-for-multiple-supports-of-matching-pursuit-ss-msmp-algorithm
#14
Israa Shaker Tawfic, Sema Koc Kayhan
Compressed sensing (CS) is a new field used for signal acquisition and design of sensor that made a large drooping in the cost of acquiring sparse signals. In this paper, new algorithms are developed to improve the performance of the greedy algorithms. In this paper, a new greedy pursuit algorithm, SS-MSMP (Split Signal for Multiple Support of Matching Pursuit), is introduced and theoretical analyses are given. The SS-MSMP is suggested for sparse data acquisition, in order to reconstruct analog and efficient signals via a small set of general measurements...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28184401/biodegradable-vascular-stents-with-high-tensile-and-compressive-strength-a-novel-strategy-for-applying-monofilaments-via-solid-state-drawing-and-shaped-annealing-processes
#15
Seung Hyuk Im, Chang Yong Kim, Youngmee Jung, Yangsoo Jang, Soo Hyun Kim
Monofilaments such as those consisting of polyamide (PA), polydioxanone (PDS), and poly(vinylidene fluoride) (PVDF), have been commonly used in various industries. However, most are non-biodegradable, which is unfavorable for many biomedical applications. Although biodegradable polymers offer significant benefits, they are still limited by their weak mechanical properties, which is an obstacle for use as a biomaterial that requires high strength. To overcome the current limitations of biodegradable monofilaments, a novel solid-state drawing (SSD) process was designed to significantly improve the mechanical properties of both PA and poly(l-lactic acid) (PLLA) monofilaments in this study...
February 10, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28179894/vestibulo-ocular-reflex-stabilization-after-vestibular-schwannoma-surgery-a-story-told-by-saccades
#16
Angel Batuecas-Caletrio, Jorge Rey-Martinez, Gabriel Trinidad-Ruiz, Eusebi Matiño-Soler, Santiago Santa Cruz-Ruiz, Angel Muñoz-Herrera, Nicolas Perez-Fernandez
OBJECTIVE: To evaluate vestibular compensation via measurement of the vestibulo-ocular reflex (VOR) following vestibular schwannoma surgery and its relationship with changes in saccades strategy after surgery. PATIENTS: Thirty-six consecutive patients with vestibular schwannomas, without brainstem compression, underwent surgical resection. Patients were recruited from University Hospital of Salamanca, Spain. METHODS: We assessed the age, sex, tumor size, degree of canalicular weakness, and preoperative video head impulse test (gain and saccade organization measured with PR score)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28179160/tubular-collagen-scaffolds-with-radial-elasticity-for-hollow-organ-regeneration
#17
Luuk R Versteegden, Kenny A van Kampen, Heinz P Janke, Dorien M Tiemessen, Theo G Hafmans, Edwin A Roozen, Roger M Lomme, Harry van Goor, Egbert Oosterwijk, Wout F Feitz, Toin H van Kuppevelt, Willeke F Daamen
: Tubular collagen scaffolds have been used for the repair of damaged hollow organs in regenerative medicine, but they generally lack the ability to reversibly expand in radial direction, a physiological characteristic seen in many native tubular organs. In this study, tubular collagen scaffolds were prepared that display a shape recovery effect and therefore exhibit radial elasticity. Scaffolds were constructed by compression of fibrillar collagen around a star-shaped mandrel, mimicking folds in a lumen, a typical characteristic of empty tubular hollow organs, such as ureter or urethra...
February 5, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28176970/percutaneous-vertebroplasty-and-interventional-tumor-removal-for-malignant-vertebral-compression-fractures-and-or-spinal-metastatic-tumor-with-epidural-involvement-a-prospective-pilot-study
#18
Yi-Feng Gu, Qing-Hua Tian, Yong-Dong Li, Chun-Gen Wu, Yan Su, Hong-Mei Song, Cheng-Jian He, Dong Chen
OBJECTIVE: The aim of this study was to compare the efficacy of percutaneous vertebroplasty (PVP) and interventional tumor removal (ITR), with PVP alone for malignant vertebral compression fractures and/or spinal metastatic tumor with epidural involvement. PATIENTS AND METHODS: A total of 124 patients were selected for PVP and ITR (n = 71, group A) and PVP alone (n = 53, group B). A 14 G needle and guide wire were inserted into the vertebral body, followed by sequential dilatation of the tract until the last cannula reached the anterior portion of the pedicle...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28168185/optimal-chest-compression-rate-and-compression-to-ventilation-ratio-in-delivery-room-resuscitation-evidence-from-newborn-piglets-and-neonatal-manikins
#19
REVIEW
Anne Lee Solevåg, Georg M Schmölzer
Cardiopulmonary resuscitation (CPR) duration until return of spontaneous circulation (ROSC) influences survival and neurologic outcomes after delivery room (DR) CPR. High quality chest compressions (CC) improve cerebral and myocardial perfusion. Improved myocardial perfusion increases the likelihood of a faster ROSC. Thus, optimizing CC quality may improve outcomes both by preserving cerebral blood flow during CPR and by reducing the recovery time. CC quality is determined by rate, CC to ventilation (C:V) ratio, and applied force, which are influenced by the CC provider...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28165433/multichannel-and-wide-angle-sar-imaging-based-on-compressed-sensing
#20
Chao Sun, Baoping Wang, Yang Fang, Zuxun Song, Shuzhen Wang
The multichannel or wide-angle imaging performance of synthetic aperture radar (SAR) can be improved by applying the compressed sensing (CS) theory to each channel or sub-aperture image formation independently. However, this not only neglects the complementary information between signals of each channel or sub-aperture, but also may lead to failure in guaranteeing the consistency of the position of a scatterer in different channel or sub-aperture images which will make the extraction of some scattering information become difficult...
February 5, 2017: Sensors
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