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https://www.readbyqxmd.com/read/28429962/predictors-of-restraint-use-among-child-occupants
#1
Marco Benedetti, Kathleen D Klinich, Miriam A Manary, Carol A Flannagan
OBJECTIVES: Identify factors that predict restraint use and optimal restraint use among children aged 0 to 13 years. METHODS: The dataset is a national sample of police-reported crashes for years 2010-2014 in which type of child restraint is recorded. The dataset was supplemented with demographic census data linked by driver zip code, as well as a score for the state child restraint law during the year of the crash relative to best practice recommendations for protecting child occupants...
April 21, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28427412/lack-of-interleukin-13-receptor-%C3%AE-1-delays-the-loss-of-dopaminergic-neurons-during-chronic-stress
#2
Simone Mori, Shuei Sugama, William Nguyen, Tatiana Michel, M Germana Sanna, Manuel Sanchez-Alavez, Rigo Cintron-Colon, Gianluca Moroncini, Yoshihiko Kakinuma, Pamela Maher, Bruno Conti
BACKGROUND: The majority of Parkinson's disease (PD) cases are sporadic and idiopathic suggesting that this neurodegenerative disorder is the result of both environmental and genetic factors. Stress and neuroinflammation are among the factors being investigated for their possible contributions to PD. Experiments in rodents showed that severe chronic stress can reduce the number of dopaminergic neurons in the substantia nigra pars compacta (SNc); the same cells that are lost in PD. These actions are at least in part mediated by increased oxidative stress...
April 21, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28425631/restraint-stress-increases-prolactin-mediated-phosphorylation-of-signal-transducer-and-activator-of-transcription-5-in-the-hypothalamus-and-adrenal-cortex-in-the-male-mouse
#3
S E Kirk, T Y Xie, F J Steyn, D R Grattan, S J Bunn
Prolactin is a pleiotropic peptide hormone produced by the lactotrophs in the anterior pituitary. Its rate of secretion is primarily regulated by a negative feedback mechanism whereby prolactin stimulates the activity of the tuberoinfundibular dopaminergic (TIDA) neurons, increasing their release of dopamine which accesses the pituitary via the median eminence to suppress further prolactin secretion. In addition to its well established role in lactation, circulating prolactin is secreted in response to stress, although the mechanism by which this is achieved or its cellular targets are unknown...
April 20, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28425395/comparing-phlebotomy-by-tail-tip-amputation-facial-vein-puncture-and-tail-vein-incision-in-c57bl-6-mice-by-using-physiologic-and-behavioral-metrics-of-pain-and-distress
#4
Elizabeth S Moore Thomas A Cleland Wendy O Williams Christine M Peterson Bhupinder Singh Teresa L Southard Bret Pasch Rachael N Labitt And Erin K Daugherity
Tail tip amputation with minimal restraint is not widely used for mouse phlebotomy. In part, this infrequency may reflectpolicies influenced by tail tip amputation procedures for genotyping, which involve greater handling and tissue removal. Toassess tail tip amputation with minimal restraint as a phlebotomy technique, we compared it with 2 more common methods:scruffing with facial vein puncture and lateral tail vein incision with minimal restraint. Blood glucose levels, audible and ultrasonic vocalizations, postphlebotomy activity and grooming behavior, open field and elevated plus maze behaviors,nest-building scores, and histologic changes at the phlebotomy site were evaluated...
April 19, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28423901/estimation-of-nanodiamond-surface-charge-density-from-zeta-potential-and-molecular-dynamics-simulations
#5
Zhenpeng Ge, Yi Wang
Molecular dynamics simulations of nanoparticles (NPs) are increasingly used to study their interactions with various biological macromolecules. Such simulations generally require detailed knowledge of the surface composition of the NP under investigation. Even for some well-characterized nanoparticles, however, this knowledge is not always available. An example is nanodiamond, a nanoscale diamond particle with surface dominated by oxygen-containing functional groups. In this work, we explore using the harmonic restraint method developed by Venable et al...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28420918/the-role-of-psychological-eating-styles-in-obesity-among-turkish-adolescents-a-cross-sectional-study
#6
Nalan Hakime Nogay
OBJECTIVE: To determine the relationship between eating behaviours and adiposity indicators including body mass index, waist-hip ratio and waist-height ratio in adolescents. METHODS: This descriptive, cross-sectional study was conducted at Kirklareli University Health College, Kirklareli, Turkey, from April to June 2014, and comprised students of the 2013-14 academic year. Height and weight were measured and students' body mass indexes were calculated. Waist and hip circumferences were measured...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28417851/nuclear-medicine-techniques-in-pediatric-bone-imaging
#7
REVIEW
Laura A Drubach
An important mandate when imaging pediatric patients is the reduction of radiation exposure to the lowest possible level consistent with good quality diagnostic imaging, so individual selection of radiopharmaceutical dosage and imaging technique is essential. Although the logistics of image acquisition and the approach to interpretation mirror the more common use in adults, the challenges of imaging young children typically require greater attention to patient preparation, positioning, and supervision during imaging, with the use of parental or family engagement in the procedure, gentle restraint, and occasionally the need for sedation...
May 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28417435/lachnospiraceae-shift-in-the-microbial-community-of-mice-faecal-sample-effects-on-water-immersion-restraint-stress
#8
Shiyin Li, Zelin Wang, Yun Yang, Sha Yang, Chenchen Yao, Kaiyun Liu, Sixin Cui, Quanming Zou, Hongwu Sun, Gang Guo
Stress, including both psychological and physical stimulation, can cause changes in the microbiota and mucosal function of the gastrointestinal system. There are few research studies available about the faecal microbiota changes after stress, such as water immersion restraint stress (WIRS). Therefore, in this study, we focused on analysing the composition changes of faecal microbiota in WIRS mice. The WIRS model, in which Blab/c mice were immersed in 21 ± 2 °C water for 4 h each day for 14 days, was established...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28416210/development-of-a-continuous-motorcycle-protection-barrier-system-using-computer-simulation-and-full-scale-crash-testing
#9
Ali O Atahan, J Marten Hiekmann, Jeffrey Himpe, Joseph Marra
Road restraint systems are designed to minimize the undesirable effects of roadside accidents and improve safety of road users. These systems are utilized at either side or median section of roads to contain and redirect errant vehicles. Although restraint systems are mainly designed against car, truck and bus impacts there is an increasing pressure by the motorcycle industry to incorporate motorcycle protection systems into these systems. In this paper development details of a new and versatile motorcycle barrier, CMPS, coupled with an existing vehicle barrier is presented...
April 15, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28415149/integrating-teamstepps-%C3%A2-into-ambulatory-reproductive-health-care-early-successes-and-lessons-learned
#10
Maureen E Paul, Laura E Dodge, Evelyn Intondi, Guzey Ozcelik, Ken Plitt, Michele R Hacker
BACKGROUND: Most medical teamwork improvement interventions have occurred in hospitals, and more efforts are needed to integrate them into ambulatory care settings. In 2014, Affiliates Risk Management Services, Inc. (ARMS), the risk management services organization for a large network of reproductive health care organizations in the United States, launched a voluntary 5-year initiative to implement a medical teamwork system in this network using the TeamSTEPPS model. This article describes the ARMS initiative and progress made during the first 2 years, including lessons learned...
April 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28414545/modular-use-of-human-body-models-of-varying-levels-of-complexity-validation-of-head-kinematics
#11
William Decker, Bharath Koya, Matthew L Davis, F Scott Gayzik
Objective The significant computational resources required to execute detailed human body finite element models has motivated the development of faster running simplified models (e.g. GHBMC M50-OS). Previous studies have demonstrated the ability to modularly incorporate the validated GHBMC M50-O brain model into the simplified model (GHBMC M50-OS+B), which allows for localized analysis of the brain in a fraction of the computation time required for the detailed model. The objective of this study is to validate the head and neck kinematics of the GHBMC M50-O and M50-OS (detailed and simplified versions of the same model) against human volunteer test data in frontal and lateral loading...
April 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28412887/preventing-and-de-escalating-aggressive-behavior-among-adult-psychiatric-patients-a-systematic-review-of-the-evidence
#12
Bradley N Gaynes, Carrie L Brown, Linda J Lux, Kimberly A Brownley, Richard A Van Dorn, Mark J Edlund, Emmanuel Coker-Schwimmer, Rachel Palmieri Weber, Brian Sheitman, Theodore Zarzar, Meera Viswanathan, Kathleen N Lohr
OBJECTIVE: The project goal was to compare the effectiveness of strategies to prevent and de-escalate aggressive behaviors among psychiatric patients in acute care settings, including interventions for reducing use of seclusion and restraint. METHODS: Relevant databases were systematically reviewed for comparative studies of violence prevention and de-escalation strategies involving adult psychiatric patients in acute care settings. Studies (trials and cohort studies) were required to report on aggression or seclusion or restraint outcomes...
April 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28408300/%C3%AE-9-nachr-knockout-mice-exhibit-dysregulation-of-stress-responses-affect-and-reward-related-behaviour
#13
Sarasa A Mohammadi, Thomas J Burton, MacDonald J Christie
The α9α10-subtype of nicotinic acetylcholine receptor (nAChR) has recently garnered interest in biomedicine and is being pursued as an analgesic target. However, the receptor exhibits diverse tissue distribution, the function of which is known to varying degrees, and targeting this receptor for clinical treatments without a broad understanding of its function may have adverse consequences. The α9α10-nAChR is expressed in the adrenal and pituitary glands, suggesting a potential role in the stress response, but little is known about its function in this tissue...
April 10, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28403166/functional-decay-in-tree-community-within-tropical-fragmented-landscapes-effects-of-landscape-scale-forest-cover
#14
Larissa Rocha-Santos, Maíra Benchimol, Margaret M Mayfield, Deborah Faria, Michaele S Pessoa, Daniela C Talora, Eduardo Mariano-Neto, Eliana Cazetta
As tropical rainforests are cleared, forest remnants are increasingly isolated within agricultural landscapes. Understanding how forest loss impacts on species diversity can, therefore, contribute to identifying the minimum amount of habitat required for biodiversity maintenance in human-modified landscapes. Here, we evaluate how the amount of forest cover, at the landscape scale, affects patterns of species richness, abundance, key functional traits and common taxonomic families of adult trees in twenty Brazilian Atlantic rainforest landscapes...
2017: PloS One
https://www.readbyqxmd.com/read/28402533/caregiver-perspectives-about-using-antipsychotics-and-other-medications-for-symptoms-of-dementia
#15
John William Kerns, Jonathan D Winter, Katherine M Winter, Christine C Kerns, Rebecca S Etz
Background and Objectives: To avoid "chemical restraints," policies and guidelines have been implemented to curb the use of medications for behavioral and psychological symptoms of dementia (BPSD). Antipsychotics have been particularly targeted because of their rare severe side effects. Consequently, caregiver directed non-pharmacologic therapies have increased while medication use for BPSD has diminished. Despite such initiatives, however, antipsychotics continue to be prescribed "off-label" for roughly 20% of nursing home patients...
April 11, 2017: Gerontologist
https://www.readbyqxmd.com/read/28401069/a-novel-restraint-device-for-injection-of-galleria-mellonella-larvae-that-minimizes-the-risk-of-accidental-operator-needle-stick-injury
#16
James P Dalton, Benedict Uy, Simon Swift, Siouxsie Wiles
Larvae of the insect Galleria mellonella are increasingly being used for studying pathogenic microbes and their virulence mechanisms, and as a rapid model for screening novel antimicrobial agents. The larvae (waxworms) are most frequently infected by injection of pathogenic organisms into the haemocoel through the insect's prolegs. The mostly widely used method for restraining the waxworms for injection is by grasping them between the operator's fingers, which puts the operator at risk of needle stick injury, an important consideration when working with highly pathogenic and/or drug-resistant microorganisms...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28399786/non-constrained-implant-arthroplasty-for-the-distal-radioulnar-joint
#17
B D Adams, J L Gaffey
A variety of surgical techniques are used to treat the arthritic distal radioulnar joint, which is influenced by aetiology and previous procedures. Four types of ulnar head arthroplasty exist: total ulnar head, partial ulnar head, unlinked total distal radioulnar joint, and linked distal radioulnar joint. Although long-term outcome studies are sparse, short-term clinical and biomechanical studies have shown encouraging results, leading to expanded indications. Based on our experience and a literature review, patients are advised that pain is improved but minor pain is common after strenuous activity...
May 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28399762/rcn-consultation-will-reveal-nurses-appetite-for-action
#18
Matthew Mckew
The RCN is to consult nurses on how it should respond to continuing pay restraint - including whether members should consider taking industrial action.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28399731/finally-getting-serious
#19
Clare Fear
Hurrah to the RCN for its decision to consult its members about how to respond to ongoing pay restraint. Finally we are getting somewhere. I was seriously considering switching to Unison. The RCN has some great resources, but never seemed militant enough.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28399153/disinhibition-of-negative-true-self-for-identity-reconstructions-in-cyberspace-advancing-self-discrepancy-theory-for-virtual-setting
#20
Chuan Hu, Sameer Kumar, Jiao Huang, Kurunathan Ratnavelu
In face-to-face communications, to avoid sanctions and disapproval from others, people are more likely to hide negative aspects of their true self (such as socially undesirable personalities, minds, beliefs and consciousness) to avoid conflict with social norms and laws. The anonymity of cyberspace provides people a unique environment to behave more freely and openly with less restraint from the real word. Existing research related to online true self expression has mainly explored true self as an independent aspect of self...
2017: PloS One
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