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https://www.readbyqxmd.com/read/29909602/traumatic-stress-among-school-aged-pediatric-surgery-patients-and-their-parents
#1
Amichai Ben Ari, Daniella Margalit, Raphael Udassin, Fortu Benarroch
INTRODUCTION:  Since hospitalization can be a traumatic event for children, many of them may suffer from a cluster of chronic psychological and emotional difficulties called Pediatric Medical Traumatic Stress (PMTS). Although PMTS causes considerable functional impairment and psychological distress and may decrease the children's compliance with post-surgical care, awareness of this condition is low and thus not enough effort is made to prevent it. The objective of this study is to assess prospectively the prevalence and characteristics of PMTS in school-age children following hospitalization in a general pediatric surgery ward and in their parents, which has not been documented before...
June 17, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29909577/population-pharmacokinetic-model-for-tumescent-lidocaine-in-women-undergoing-breast-cancer-surgery
#2
Camille Riff, Aurélie Bourgoin, Amelie Marsot, Laurent Allanioux, Marc Leone, Olivier Blin, Romain Guilhaumou
PURPOSE: Tumescent lidocaine anesthesia (TLA) is an opportunity to perform mastectomy for breast cancer without general anesthesia in elderly women. Few reports are available on the pharmacokinetics of lidocaine in a context of TLA during a unilateral mastectomy. The aim of this study was to describe lidocaine pharmacokinetics in elderly women undergoing breast cancer surgery after TLA and to explore the risk of the toxicity of this technique. METHODS: A prospective study was conducted to examine the pharmacokinetics of lidocaine in women undergoing TLA...
June 16, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29909471/pet-ct-and-prediction-of-thyroid-cancer-in-patients-with-follicular-neoplasm-or-atypia
#3
Thao T Nguyen, Natascha G E Lange, Anne L Nielsen, Anders Thomassen, Helle Døssing, Christian Godballe, Max Rohde
PURPOSE: To examine whether addition of 18 F-fluoro-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) to fine needle aspiration biopsy (FNAB) would improve prediction of thyroid cancer in patients with FNAB-derived follicular neoplasm or atypia, classified according to focal, multifocal, diffuse, or no FDG uptake. MATERIALS AND METHODS: Consecutive patients with FNAB-derived follicular neoplasm or atypia planned for surgery from September 2013 to March 2016 were prospectively included and considered for analysis...
June 16, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29909466/successful-non-operative-management-of-haemodynamically-unstable-traumatic-splenic-injuries-4-year-case-series-in-a-uk-major-trauma-centre
#4
Richard A Armstrong, Andrew Macallister, Benjamin Walton, Julian Thompson
PURPOSE: Management of traumatic splenic injury may be operative or non-operative (including embolization and conservative management). Traditionally, haemodynamic instability has been an indication for operative intervention. We aimed to report our experience of managing traumatic splenic injury at a regional major trauma centre in the UK over a 4-year period, with a particular focus on the non-operative management (NOM) of haemodynamically unstable patients. METHODS: All patients with splenic injuries admitted to North Bristol NHS Trust from April 2012 to March 2016 were included...
June 16, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29909420/neopterin-as-a-biomarker-in-patients-with-pulmonary-arterial-hypertension-and-chronic-thromboembolic-pulmonary-hypertension
#5
Anna Smukowska-Gorynia, Justyna Marcinkowska, Ewa Chmara, Katarzyna Malaczynska-Rajpold, Sylwia Slawek-Szmyt, Artur Cieslewicz, Magdalena Janus, Aleksander Araszkiewicz, Stanislaw Jankiewicz, Anna Komosa, Anna Olasinska-Wisniewska, Iga Tomaszewska, Tatiana Mularek-Kubzdela
BACKGROUND: Upregulation of the immune system is regarded to play an important role in the etiopathobiology of pulmonary arterial hypertension (PAH) and inoperable chronic thromboembolic pulmonary hypertension (CTEPH). To the best of our knowledge, neopterin (NP) has never been investigated in patients with PAH and CTEPH. OBJECTIVES: The aim of the study was to evaluate the concentration of NP in blood in order to examine its impact on outcome and relationship with disease severity in that population...
June 15, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29909410/what-is-the-role-of-soluble-urokinase-type-plasminogen-activator-in-renal-disease
#6
Moin A Saleem
Soluble urokinase-type plasminogen activator -(suPAR) is an inflammatory signal with pleiotropic biological effects depending on context and post-translational modifications. Recently, [Hayek, et al: Nat Med 2017; 23: 945-953] it has been found that there is a link between suPAR and renal disease in several guises, and a key question is whether it is a driver or a marker of renal disease, and if so of which types of kidney damage. Subject of Review: Circulating suPAR has been postulated to cause acute proteinuric kidney disease, specifically focal segmental glomerulosclerosis (FSGS), though both the animal models and clinical data in the original reports have been challenged...
June 15, 2018: Nephron
https://www.readbyqxmd.com/read/29909400/effects-of-electroacupuncture-on-bladder-and-bowel-function-in-patients-with-transverse-myelitis-a-prospective-observational-study
#7
Jiani Wu, Yanjun Cheng, Zongshi Qin, Xiaoxu Liu, Zhishun Liu
OBJECTIVE: To preliminarily explore the effect of electroacupuncture (EA) on bladder and bowel dysfunction in patients with transverse myelitis. METHODS: Sixteen participants were treated with EA at bilateral BL32, BL33, and BL35 once a day, five times a week for the first 4 weeks, and once every other day, three times a week for the following 4 weeks. Patients were then followed up for 6 months. Bladder and bowel function, and the safety of EA, were assessed...
June 16, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/29909318/metabolome-based-classification-of-artichoke-leaf-a-prospect-for-phyto-equivalency-of-its-different-leaf-origins-and-commercial-preparations
#8
Mohamed A Farag, Mahmoud F Elsebai, Amira R Khattab
The growing interest in assuring phytomedicines efficacy and moreover the increase in requirements for its safety drive the development of analytical methods for its quality control assurance. Herein, we present a nuclear magnetic resonance (NMR) fingerprinting approach of artichoke leaf material from different origins and in its commercial preparations. Under optimized conditions, we were able to simultaneously identify 23 metabolites including sugars, amino and organic acids, sesquiterpene lactones, flavones, cinnamates, inulin, fatty acids and nitrogenous bases...
May 30, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29909296/anterior-cruciate-ligament-reconstruction-with-the-tape-locking-screw-tls-and-a-short-hamstring-graft-clinical-evaluation-of-61-cases-with-a-minimum-12-months-follow-up
#9
Benoît Orfeuvre, Régis Pailhé, Loïc Sigwalt, Brice Rubens Duval, Gabriel Lateur, Stéphane Plaweski, Dominique Saragaglia
INTRODUCTION: The TLS® technique for anterior cruciate ligament (ACL) reconstruction has the advantages of using only one hamstring tendon (semitendinosus) by preparing a short graft secured with screws and braided strips. The theoretical pitfall of this technique is that the graft length is determined arbitrarily. Thus, if the blind tunnels are not long enough, it will be impossible to tension the graft properly upon fixation. The primary objective of this study was to determine the postoperative side-to-side difference in knee laxity...
June 14, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29909268/the-relationship-between-intrapartum-cerebroplacental-ratio-and-adverse-perinatal-outcomes-in-term-fetuses
#10
Natthicha Chainarong, Chusana Petpichetchian
OBJECTIVES: The cerebroplacental ratio (CPR) Doppler has been proposed as an instrument for predicting adverse perinatal outcomes particularly during antepartum period. Abnormal CPR is associated with non-reassuring fetal status requiring operative delivery, low Apgar score and neonatal complications. The aim of this study was to assess the role of CPR Doppler in the labor triage suite, so as to identify fetuses at risk for non-reassuring status as well as other adverse perinatal outcomes...
June 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29909263/patient-reported-pelvic-floor-symptoms-5-years-after-hysterectomy-with-or-without-prolapse-surgery
#11
Pauliina Aukee, Niina Humalajärvi, Matti V Kairaluoma, Antti Valpas, Beata Stach-Lempinen
OBJECTIVE: The aim of this study was to evaluate the effect of hysterectomy with or without concomitant prolapse surgery on subject-reported pelvic floor disorders (PFD) with a 5-year follow-up. STUDY DESIGN: This prospective longitudinal study was carried out in two Finnish central hospitals among 286 women who had undergone hysterectomy for benign reasons. The presence of urinary incontinence, urinary frequency, feeling of vaginal bulging, constipation and anal incontinence was evaluated at baseline, 1 and 5 years postoperatively...
June 8, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29909249/processed-red-meat-intake-and-risk-of-copd-a-systematic-review-and-dose-response-meta-analysis-of-prospective-cohort-studies
#12
Asma Salari-Moghaddam, Alireza Milajerdi, Bagher Larijani, Ahmad Esmaillzadeh
BACKGROUND & AIMS: No earlier study has summarized findings from previous publications on processed red meat intake and risk of Chronic Obstructive Pulmonary Disease (COPD). This systematic review and meta-analysis was conducted to examine the association between processed red meat intake and COPD risk. METHODS: We searched in PubMed/Medline, ISI Web of Knowledge, Scopus, EMBASE and Google Scholar up to April 2018 to identify relevant studies. Prospective cohort studies that considered processed red meat as the exposure variable and COPD as the main outcome variable or as one of the outcomes were included in the systematic review...
June 1, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29909244/change-in-viral-bronchiolitis-management-in-hospitals-in-the-uk-after-the-publication-of-nice-guideline
#13
Rachael Barr, Elliott J Carande, Andrew J Pollard, Simon B Drysdale
BACKGROUND: Viral bronchiolitis is one of the most common causes of hospitalisation in young infants. It has previously been shown that many United Kingdom (UK) hospital Trusts were not compliant with many aspects of the National Institute for Health and Care Excellence (NICE) bronchiolitis guideline prior to its publication. OBJECTIVES: This study aimed to investigate changes in the management of bronchiolitis by hospital Trusts between 2015 (before NICE guideline publication) and 2017, after publication...
June 12, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29909229/functional-evaluation-of-bilateral-subtalar-arthroereisis-for-the-correction-of-flexible-flatfoot-in-children-1-year-follow-up
#14
Paolo Caravaggi, Giada Lullini, Lisa Berti, Sandro Giannini, Alberto Leardini
BACKGROUND: Flexible flatfoot (FFF) is a common alteration of the foot diagnosed in the pediatric population causing pain and decreased quality of life. Surgical treatment via arthroereisis of the subtalar joint can be recommended when non-invasive options do not result in sufficient pain relief. While clinical outcome of subtalar joint arthroereisis is generally positive, no functional evaluation has thus far been reported following surgery. RESEARCH QUESTION: The aim of this study was to assess the effects of two arthroereisis implants for the correction of bilateral FFF on foot and lower limb biomechanics during gait...
June 11, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29909221/identification-of-microplastics-using-raman-spectroscopy-latest-developments-and-future-prospects
#15
REVIEW
Catarina F Araujo, Mariela M Nolasco, Antonio M P Ribeiro, Paulo J A Ribeiro-Claro
Widespread microplastic pollution is raising growing concerns as to its detrimental effects upon living organisms. A realistic risk assessment must stand on representative data on the abundance, size distribution and chemical composition of microplastics. Raman microscopy is an indispensable tool for the analysis of very small microplastics (<20 μm). Still, its use is far from widespread, in part due to drawbacks such as long measurement time and proneness to spectral distortion induced by fluorescence...
June 6, 2018: Water Research
https://www.readbyqxmd.com/read/29909215/modeling-neurodegeneration-in-patients-with-visual-pathway-tumors-by-retinal-optical-coherence-tomography
#16
Ana Banc, Cristina Stan, Alexandra-Stefania Berghe, Tudor Catalin Drugan, Ioan-Stefan Florian
OBJECTIVE: Optical coherence tomography (OCT) is a non-invasive high-resolution imaging technique which was suggested to be a powerful biomarker of neurodegeneration. The objective of our study is to assess the pattern of retinal OCT changes in patients with visual pathway tumors. METHODS: A prospective clinical study was conducted and patients with single cerebral tumors with potential of compression on the visual pathway were included. Patients with multiple and/or metastatic tumors were excluded...
June 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29909193/the-inadequate-bladder-template-its-effect-on-outcomes-in-classic-bladder-exstrophy
#17
Heather N Di Carlo, Mahir Maruf, John Jayman, Karl Benz, Mathew Kasprenski, John P Gearhart
INTRODUCTION: Newborns with classic bladder exstrophy (CBE) may present with a bladder template that is inadequate for closure in the neonatal period (figure). In these cases, a delayed primary closure (DPC) is conducted to permit growth of the bladder template. This study reports the surgical and long-term urinary continence outcomes of poor template CBE patients undergoing DPC and compares them to patients who underwent DPC for reasons unrelated to bladder quality (i.e., prematurity, comorbidities, or a late referral)...
May 10, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29909187/epilepsia-partialis-continua-correlation-of-semiology-outcome-and-electrophysiologic-features
#18
Murat Mert Atmaca, Nerses Bebek, Elif Kocasoy-Orhan, Candan Gürses
OBJECTIVE: Epilepsia partialis continua (EPC) is a special form of cortical epilepsy. Several studies have described the ictal and interictal electroencephalography (EEG) findings in patients with EPC; however, lateralizing and localizing values of these findings have been evaluated rarely. This study investigated the correlation of semiologic and EEG findings, and outcomes in patients with EPC. PATIENTS AND METHODS: Clinical and EEG findings and outcomes, and their correlations were studied prospectively in 15 patients who were diagnosed as having EPC upon presentation to Istanbul Medical Faculty Hospital between January 2010 and April 2014, and retrospectively in 5 previously evaluated patients...
June 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29909166/nanoparticle-plant-interaction-implications-in-energy-environment-and-agriculture
#19
REVIEW
Prabhat Kumar Rai, Vanish Kumar, SangSoo Lee, Nadeem Raza, Ki-Hyun Kim, Yong Sik Ok, Daniel C W Tsang
In the recent techno-scientific revolution, nanotechnology has gained popularity at a rapid pace in different sectors and disciplines, specifically environmental, sensing, bioenergy, and agricultural systems. Controlled, easy, economical, and safe synthesis of nanomaterials is desired for the development of new-age nanotechnology. In general, nanomaterial synthesis techniques, such as chemical synthesis, are not completely safe or environmentally friendly due to harmful chemicals used or to toxic by-products produced...
June 14, 2018: Environment International
https://www.readbyqxmd.com/read/29909120/integrated-in-silico-in-vitro-strategy-for-screening-of-some-traditional-egyptian-plants-for-human-aromatase-inhibitors
#20
Hend M Dawood, Reham S Ibrahim, Eman Shawky, Hala M A Hammoda, Aly M Metwally
ETHNOPHARMACOLOGICAL RELEVANCE: Aromatase enzyme (CYP19) is widely known as a critical target protein for treating hormone-dependent breast cancer. Natural products from traditional medicinal plants continue to be an active source of aromatase inhibitors. Meanwhile, high cost of experimental work and low hit rate associated with HTS have stimulated the implementation of in-silico virtual screening to resolve these pitfalls, where coupling of both classical wet lab procedure and VS may offer a more deepened access to bioactive compounds with less work and time waste...
June 14, 2018: Journal of Ethnopharmacology
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