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https://www.readbyqxmd.com/read/29236379/alcohol-consumption-and-low-risk-drinking-guidelines-among-adults-a-cross-sectional-analysis-from-alberta-s-tomorrow-project
#1
Darren R Brenner, Tiffany R Haig, Abbey E Poirier, Alianu Akawung, Christine M Friedenreich, Paula J Robson
INTRODUCTION: Moderate to heavy alcohol consumption is a risk factor for all-cause mortality and cancer incidence. Although cross-sectional data are available through national surveys, data on alcohol consumption in Alberta from a large prospective cohort were not previously available. The goal of these analyses was to characterize the levels of alcohol consumption among adults from the Alberta's Tomorrow Project in the context of cancer prevention guidelines. Furthermore, we conducted analyses to examine the relationships between alcohol consumption and other high-risk or risk-related behaviours...
December 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29236378/urinary-bisphenol-a-and-obesity-in-adults-results-from-the-canadian-health-measures-survey
#2
Minh T Do, Vicky C Chang, Michelle A Mendez, Margaret de Groh
INTRODUCTION: Exposure to bisphenol A (BPA) has been shown to affect lipid metabolism and promote weight gain in animal studies. Recent epidemiological studies also support a link between BPA and obesity in human populations, although many were limited to a single adiposity measure or have not considered potential confounding by dietary factors. The purpose of this study is to examine associations between urinary BPA and adiposity measures in a nationally representative sample of Canadian adults...
December 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29236344/association-between-urologic-malignancies-and-end-stage-renal-disease-a-meta-analysis
#3
Panagiotis Kompotiatis, Charat Thongprayoon, Sandhya Manohar, Wisit Cheungpasitporn, Maria L Gonzalez Suarez, Iasmina M Craici, Michael A Mao, Sandra M Herrmann
OBJECTIVE: Previous studies have suggested a higher incidence of urologic malignancies in end-stage renal disease (ESRD) patients. However, incidence trends of urologic malignancies in ESRD patients remain unclear. The study's aims were 1) to investigate the pooled incidence/incidence trends and 2) to assess the risk of urologic malignancies in ESRD patients. METHODS: A literature search was conducted using MEDLINE, EMBASE and Cochrane Database from inception through April 2017...
December 13, 2017: Nephrology
https://www.readbyqxmd.com/read/29236339/physical-activity-level-among-children-recovering-from-severe-acute-malnutrition
#4
Esther Babirekere-Iriso, Maren Johanne Heilskov Rytter, Hanifa Namusoke, Ezekiel Mupere, Kim F Michaelsen, Søren Brage, Ken D Stark, Lotte Lauritzen, André Briend, Henrik Friis, Daniel Faurholt-Jepsen
OBJECTIVE: To assess the level and predictors of physical activity at discharge among children recovering from severe acute malnutrition (SAM). METHODS: We conducted a prospective study among 69 children 6 - 59 months of age admitted with SAM for nutritional rehabilitation at Mulago National Referral Hospital, Uganda. Using hip-mounted tri-axial accelerometers, we measured physical activity expressed as counts per minute (cpm) during the last three days of hospital treatment...
December 13, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29236338/inflammatory-cytokine-and-c-reactive-protein-concentrations-in-dogs-with-systemic-inflammatory-response-syndrome
#5
Kris Gommeren, Isabelle Desmas, Alexandra Garcia, Natalie Bauer, Andreas Moritz, Joachim Roth, Dominique Peeters
OBJECTIVE: To evaluate C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α) kinetics in dogs with a systemic inflammatory response syndrome (SIRS) presented to an emergency service. We hypothesized serum CRP concentrations would increase and vary during hospitalization, and would correlate with plasma IL-6 and TNF-α concentrations, vary in magnitude according to the underlying disease, and predict survival. DESIGN: Prospective, observational, clinical study...
December 13, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29236303/impact-of-antimicrobial-stewardship-program-on-hospitalized-patients-at-the-intensive-care-unit-a-prospective-audit-and-feedback-study
#6
Maher R Khdour, Hussein O Hallak, Mamoon Al-Deyab, Mowafq A Nasif, Aliaa M Khalili, Ahamad A Dallashi, Mohammad B Khofash, Michael G Scott
AIMS: Inappropriate use of antibiotics is one of the most important factors contributing to the emergence of drug resistant pathogens. The purpose of this study was to measure the clinical impact of Antimicrobial Stewardship Program (ASP) interventions on hospitalized patients at the Intensive care unit at Palestinian Medical Complex. METHODS: A prospective audit with intervention and feedback by ASP team within 48-72h of antibiotic administration began in Sep, 2015...
December 13, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29236281/preoperative-evaluation-and-intraoperative-protection-of-the-facial-nerve-in-congenital-aural-atresia
#7
Jie Li, Shouqin Zhao, Lin Yang, Yi Li, Xiaobo Ma, Danni Wang, Ran Ren, Ying Li
We conducted a prospective study to assess the value of high-resolution computed tomography (HRCT) in identifying facial nerve variations in patients with congenital aural atresia and to determine how they affect otologic reconstruction surgery. Our study population was made up of 65 patients (69 ears) aged 6 to 22 years (mean: 13.7) without regard to sex. They were classified into three groups according to their scores on the Jahrsdoerfer grading scale: 46 ears scored 8 or more, 18 had a score of 6 or 7, and 5 scored 5 or less...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29236277/clouds-of-different-colors-a-prospective-look-at-head-and-neck-surgical-resident-call-experience
#8
Jonathan Melzer
Graduate medical education programs typically set up call under the assumption that residents will have similar experiences. The terms black cloud and white cloud have frequently been used to describe residents with more difficult (black) or less difficult (white) call experiences. This study followed residents in the department of head and neck surgery during call to determine whether certain residents have a significantly different call experience than the norm. It is a prospective observational study conducted over 16 months in a tertiary care center with a resident training program in otolaryngology...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29236239/abdominal-aorta-and-pelvic-artery-calcifications-on-plain-radiographs-may-predict-mortality-in-chronic-kidney-disease-hemodialysis-and-renal-transplantation
#9
Sinee Disthabanchong, Kotcharat Vipattawat, Bunyong Phakdeekitcharoen, Chagriya Kitiyakara, Vasant Sumethkul
PURPOSE: Vascular calcification is common in chronic kidney disease (CKD) and predicts poor patient outcomes. While computed tomography is the gold standard for evaluation of vascular calcification, plain radiograph offers a simpler and less costly alternative. The calcification of abdominal aorta, iliac and femoral arteries has been evaluated by plain radiograph, but the data on their outcome predictabilities are still limited. The present study investigated the role of abdominal aortic calcification (AAC) and pelvic arterial calcification (PAC) in predicting overall morality in non-dialysis CKD stages 2-5 (CKD 2-5), maintenance hemodialysis (HD) and long-term kidney transplant (KT) patients...
December 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29236228/population-pharmacokinetic-pharmacodynamic-modeling-of-ropivacaine-in-spinal-anesthesia
#10
Zoubir Djerada, Catherine Feliu, Yoann Cazaubon, Faouzi Smati, Philippe Gomis, Dominique Guerrot, Beny Charbit, Olivier Fernandes, Jean-Marc Malinovsky
BACKGROUND: Ropivacaine is frequently used in spinal anesthesia but the relationship between plasma concentrations and sensory block level remains unknown. OBJECTIVE: The aim of this study was to assess the relationship between plasma ropivacaine concentrations and effects during spinal anesthesia. METHODS: Sixty patients aged between 18 and 82 years were included in this study after providing written informed consent. Patients were randomly assigned to receive intrathecal administration of ropivacaine 15, 20 or 25 mg...
December 13, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29236216/long-term-outcomes-of-a%C3%A2-caucasian-cohort-presenting-with-acute-coronary-syndrome-and-or-out-of-hospital-cardiac-arrest-caused-by-coronary-spasm
#11
W Vlastra, M Piek, M A van Lavieren, M E J C Hassell, B E Claessen, G W Wijntjens, T P van de Hoef, K D Sjauw, M A Beijk, R Delewi, J J Piek
BACKGROUND: Coronary artery spasm may be the underlying mechanism in up to 10% of cases of acute coronary syndrome (ACS) and sudden cardiac death. Asian individuals exhibit a 3-times greater incidence of spasm than Caucasians; this is likely due to different types of mechanisms. Consequently, solid data is limited about the long-term prognosis in Caucasian patients presenting with ACS and/or out-of-hospital cardiac arrest (OHCA) caused by coronary spasm. METHODS: Between 2002 and 2015, thirty Caucasian patients with coronary artery spasm presenting with ACS (N = 29) and/or OHCA (N = 11) were enrolled in this prospective registry...
December 13, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29236206/management-of-slipped-gastric-bands-via-creation-of-a-de-novo-tunnel-and-band-replacement-a-single-centre-experience
#12
Roshani Vijaykumar Patel, Patrick Woodburn, James R A Skipworth, William James Buchanan Smellie
BACKGROUND: A lack of clarity remains over the optimal strategy for the management of laparoscopic adjustable gastric band (LAGB) slippage, which, although rare (around 3% in our experience), can when acute result in obstruction, gastric erosion or ischaemia. Typically, slipped bands are removed acutely. The aim of this study was to explore outcomes following immediate or delayed resiting of slipped LAGBs in a single centre, comparing simple repositioning with retunnelling and replacement...
December 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29236181/ultrasound-based-logistic-regression-model-lr2-versus-magnetic-resonance-imaging-for-discriminating-between-benign-and-malignant-adnexal-masses-a-prospective-study
#13
Kanane Shimada, Koji Matsumoto, Takashi Mimura, Tetsuya Ishikawa, Jiro Munechika, Yoshimitsu Ohgiya, Miki Kushima, Yusuke Hirose, Yuka Asami, Chiaki Iitsuka, Shingo Miyamoto, Mamiko Onuki, Hajime Tsunoda, Ryu Matsuoka, Kiyotake Ichizuka, Akihiko Sekizawa
BACKGROUND: The diagnostic performances of the International Ovarian Tumor Analysis (IOTA) ultrasound-based logistic regression model (LR2) and magnetic resonance imaging (MRI) in discriminating between benign and malignant adnexal masses have not been directly compared in a single study. METHODS: Using the IOTA LR2 model and subjective interpretation of MRI findings by experienced radiologists, 265 consecutive patients with adnexal masses were preoperatively evaluated in two hospitals between February 2014 and December 2015...
December 13, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29236174/oncotype-dx%C3%A2-in-breast-cancer-patients-clinical-experience-outcome-and-follow-up-a-case-control-study
#14
Michelle G Rath, Lorenz Uhlmann, Marita Fiedler, Joerg Heil, Michael Golatta, Christine Dinkic, Andre Hennigs, Sarah Schott, Veronika Ernst, Thorsten Koch, Christof Sohn, Cosima Brucker, Joachim Rom
PURPOSE: Breast cancer is the leading cause of death from cancer in women and the most common cancer in the world [1]. To date, many patients with estrogen-receptor-positive (ER+) breast cancer are overtreated with chemotherapy when the rationale for adjuvant chemotherapy is based on clinicopathologic parameters. Different studies were able to demonstrate that a 21-gene expression assay (Oncotype DX® Genomic Health, Redwood City, CA) can predict the benefit from adjuvant chemotherapy in ER+ breast cancers [2, 3] and provide additional prognostic information independent of clinicopathological features [4]...
December 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29236173/is-surgical-plume-developing-during-routine-leeps-contaminated-with-high-risk-hpv-a-pilot-series-of-experiments
#15
Kay Neumann, Markus Cavalar, Achim Rody, Luisa Friemert, Daniel A Beyer
INTRODUCTION: Growing evidence shows a causal role of high-risk humane papillomavirus (HPV) infections in the development of head and neck cancer. A recent case report shows two patients suffering from tonsillar cancer without any risk factors apart from their work as gynecologists doing laser ablations and loop electrosurgical excision procedures (LEEP). The aim of the present investigation is to evaluate whether surgical plume resulting from routine LEEPs of HSIL of the cervix uteri might be contaminated with the DNA of high-risk HPV...
December 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29236163/evaluation-of-pain-perception-associated-with-use-of-the-magnetic-end-ureteric-double-j-stent-for-short-term-ureteric-stenting
#16
S Sevcenco, K Eredics, L Lusuardi, Hans Christoph Klingler
PURPOSE: To investigate the morbidity, complication rate, and pain perception during removal of a novel ureteric stent with a magnetic end using a-traumatic retrieval catheter. METHODS: Between November 2013 and July 2015, 151 consecutive patients who underwent semirigid ureterorenoscopy (URS) for stone removal were prospectively enrolled. Stent removal was performed under local anesthesia using a special magnetic-end stent remover 1 week following URS. At follow-up, we obtained patients' medical history, urine culture result, renal ultrasonogram, and visual analog scale (VAS) score regarding stent irritation (VAS 1) and pain during removal (VAS 2)...
December 13, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29235940/slc9b1-methylation-predicts-fetal-intolerance-of-labor
#17
Anna K Knight, Karen N Conneely, Varun Kilaru, Dawayland Cobb, Jennifer L Payne, Samantha Meilman, Elizabeth J Corwin, Zachary A Kaminsky, Anne L Dunlop, Alicia K Smith
Fetal intolerance of labor is a common indication for delivery by Caesarean section. Diagnosis is based on the presence of category III fetal heart rate tracing, which is an abnormal heart tracing associated with increased likelihood of fetal hypoxia and metabolic acidemia. This study analyzed data from 177 unique women who, during their prenatal visits (7-15 weeks and/or 24-32 weeks) to Atlanta area prenatal care clinics, consented to provide blood samples for DNA methylation (HumanMethylation450 BeadChip) and gene expression (Human HT-12 v4 Expression BeadChip) analyses...
December 13, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/29235733/intraoperative-parathyroid-aspiration-and-parathyroid-hormone-assay-during-parathyroidectomy-for-primary-hyperparathyroidism
#18
Miki Paker, Shani Fisher, Salim Mazzawi, Raul Kolodner, Dror Ashkenazi
BACKGROUND: Direct aspiration from suspected pathological tissue and rapid parathyroid hormone analysis may offer a reliable, cost effective alternative to currently used "gold standard" tests. OBJECTIVES: To validate the accuracy of intraoperative measurements of parathyroid hormone levels in parathyroid adenomas. METHODS: A prospective study included 22 patients diagnosed with primary hyperparathyroidism who underwent parathyroidectomy due to an adenoma or hyperplasia...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29235565/anthropometric-measurements-and-survival-after-a-prostate-cancer-diagnosis
#19
Megan S Farris, Kerry S Courneya, Karen A Kopciuk, S Elizabeth McGregor, Christine M Friedenreich
BACKGROUND: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. METHODS: Men diagnosed with prostate cancer (n=987) were recruited into a population-based case-control study between 1997 and 2000 then a prospective cohort study between 2000 and 2002 where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes...
December 12, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/29235564/influence-of-induction-chemotherapy-in-trimodality-therapy-eligible-oesophageal-cancer-patients-secondary-analysis-of-a-randomised-trial
#20
Yusuke Shimodaira, Rebecca S Slack, Kazuto Harada, Hsiang-Chun Chen, Tara Sagebiel, Manoop S Bhutani, Jeffrey H Lee, Brian Weston, Elena Elimova, Quan Lin, Fatemeh G Amlashi, Dilsa Mizrak Kaya, Mariela A Blum, Jack A Roth, Stephen G Swisher, Heath D Skinner, Wayne L Hofstetter, Jane E Rogers, Jaennette Mares, Irene Thomas, Dipen M Maru, Ritsuko Komaki, Garrett Walsh, Jaffer A Ajani
BACKGROUND: A randomised phase 2 trial of trimodality with or without induction chemotherapy (IC) in oesophageal cancer (EC) patients showed no advantage in overall survival (OS) or pathologic complete response rate. To identify subsets that might benefit from IC, a secondary analysis was done. METHODS: The trial had accrued 126 patients (NCT 00525915). Recursive partitioning and proportional hazards regression with interactions were performed. RESULTS: The median follow-up of surviving patients was 6...
December 12, 2017: British Journal of Cancer
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