keyword
MENU ▼
Read by QxMD icon Read
search

Oesophageal cancer

keyword
https://www.readbyqxmd.com/read/28524708/significance-of-baseline-fdg-pet-ct-scan-as-a-method-of-staging-regional-lymph-nodes-in-patients-with-operable-distal-oesophageal-or-gastroesophageal-junction-adenocarcinoma
#1
George Papaxoinis, Jamie M J Weaver, Leila Khoja, Ana Patrao, Sofia Stamatopoulou, Alia Alchawaf, Vikki Owen-Holt, Theodora Germetaki, Zoe Kordatou, Wasat Mansoor
BACKGROUND: The new American Joint Committee on Cancer eighth edition (AJCC8) staging is the first to describe separate clinical and pathology staging systems, but still has low performance to predict prognosis in patients with oesophageal/gastroesophageal junction (O/GOJ) adenocarcinoma, who are candidates for surgery. Recent studies have demonstrated that O/GOJ cancer patients with 18F-fluorodeoxyglucose (FDG) avid regional lymph nodes (RLNs) may have poor prognosis. The aim of our study was to examine whether the baseline assessment of the FDG uptake of RLN improves the prognostic accuracy of the new AJCC8 staging...
May 19, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28518409/metabolic-nodal-response-as-a-prognostic-marker-after-neoadjuvant-therapy-for-oesophageal-cancer
#2
J M Findlay, K M Bradley, L M Wang, J M Franklin, E J Teoh, F V Gleeson, N D Maynard, R S Gillies, M R Middleton
No abstract text is available yet for this article.
June 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28506698/antiproliferative-and-cytotoxic-effects-of-green-coffee-and-yerba-mate-extracts-their-main-hydroxycinnamic-acids-methylxanthine-and-metabolites-in-different-human-cell-lines
#3
M Amigo-Benavent, S Wang, R Mateos, B Sarriá, L Bravo
This work aimed at studying the effects of green coffee bean (GCBE) and yerba mate (YME) extracts, their main phenolic components (5-caffeoylquinic acid, 5-CQA; 3,5-dicaffeoylquinic acid, 3,5-DCQA) and metabolites (ferulic acid, FA; caffeic acid, CA; dihydrocaffeic acid, DHCA; and dihydroferulic acid, DHFA) along with caffeine (CAF) on the viability and proliferation of different human cell lines. Extracts (10-1000 μg/mL) and standards (10-1000 μM) were assayed in colon (Caco-2), lung (A549), oesophageal (OE-33), urinary bladder (T24) human carcinoma cells, and a non-cancer cell line (CCD-18Co)...
May 12, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28499713/long-term-outcomes-of-oesophageal-atresia-without-or-with-proximal-tracheooesophageal-fistula-gross-types-a-and-b
#4
A I Koivusalo, S J Sistonen, H G Lindahl, R J Rintala, M P Pakarinen
PURPOSE: Because of an extended gap between esophageal pouches a variety of methods are employed to treat oesophageal atresia (OA) without (type A) or with (type B) proximal tracheooesophageal fistula. This retrospective observational study describes their single centre long-term outcomes from 1947 to 2014. METHODS: Of 693 patients treated for OA 68 (9.7%) had type A (n=58, 8.3%) or B (n=10, 1.4%). Hospital records were reviewed. Main outcome measures were survival and oral intake...
May 1, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28499662/-acute-toxicity-of-breast-cancer-irradiation-with-modulated-intensity-by-tomotherapy-%C3%A2
#5
N Aoulad, C Massabeau, B de Lafontan, L Vieillevigne, G Hangard, C Ciprian, L Chaltiel, É Moyal, F Izar
PURPOSE: Helical radiation intensity modulated by tomotherapy improves dose distribution to complex and large volumes. The aim of the study was to assess acute toxicity of this technique during breast cancer irradiation after conserving surgery or mastectomy. PATIENTS AND METHODS: Cutaneous toxicities, lung and oesophageal side effects, and breast lymphedema were retrospectively collected according to the Common Terminology Criteria for Adverse Events Version 4...
May 9, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28499658/-radiotherapy-volume-delineation-based-on-18-f-fluorodeoxyglucose-positron-emission-tomography-for-locally-advanced-or-inoperable-oesophageal-cancer
#6
J Encaoua, R Abgral, C Leleu, O El Kabbaj, P Caradec, D Bourhis, O Pradier, U Schick
PURPOSE: To study the impact on radiotherapy planning of an automatically segmented target volume delineation based on ((18)F)-fluorodeoxy-D-glucose (FDG)-hybrid positron emission tomography-computed tomography (PET-CT) compared to a manually delineation based on computed tomography (CT) in oesophageal carcinoma patients. METHODS AND MATERIALS: Fifty-eight patients diagnosed with oesophageal cancer between September 2009 and November 2014 were included. The majority had squamous cell carcinoma (84...
May 9, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28498967/surgical-resection-after-neoadjuvant-chemoradiation-for-oesophageal-adenocarcinoma-what-is-the-optimal-timing
#7
David N Ranney, Michael S Mulvihill, Babatunde A Yerokun, Zachary Fitch, Zhifei Sun, Chi-Fu Yang, Thomas A D'Amico, Matthew G Hartwig
OBJECTIVES: The purpose of this study was to determine the optimal timing of surgical resection of oesophageal adenocarcinoma following neoadjuvant chemoradiotherapy (nCRT). METHODS: nCRT before resection of oesophageal adenocarcinoma yields improved overall and progression-free survival. Despite the wide acceptance of tri-modal therapy, the optimal timing of surgical resection after nCRT is not well defined and existing studies are limited. Adults with Stage II/III oesophageal adenocarcinoma undergoing nCRT before surgery were identified from the National Cancer Database...
May 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28493483/preoperative-imaging-and-prediction-of-oesophageal-conduit-necrosis-after-oesophagectomy-for-cancer
#8
P Lainas, D Fuks, S Gaujoux, Z Machroub, A Fregeville, T Perniceni, F Mal, B Dousset, B Gayet
BACKGROUND: Oesophageal conduit necrosis following oesophagectomy is a rare but life-threatening complication. The present study aimed to assess the impact of coeliac axis stenosis on outcomes after oesophagectomy for cancer. METHODS: The study included consecutive patients who had an Ivor Lewis procedure with curative intent for middle- and lower-third oesophageal cancer at two tertiary referral centres. All patients underwent preoperative multidetector CT with arterial phase to detect coeliac axis stenosis...
May 11, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28493326/hyperglycaemia-and-aberrated-insulin-signalling-stimulate-tumour-progression-via-induction-of-the-extracellular-matrix-component-hyaluronan
#9
Sören Twarock, Christina Reichert, Ulrike Peters, Daniel J Gorski, Katharina Röck, Jens W Fischer
Epidemiological studies have detected a higher incidence of various tumour entities in diabetic patients. However, the underlying mechanisms remain insufficiently understood. Glucose-derived pericellular and extracellular hyaluronan (HA) promotes tumour progression and development. In this study, we tested the hypothesis that a diabetic metabolic state, characterised by hyperglycaemia and concomitant aberrant insulin signalling, stimulates tumour progression via the induction of HA synthesis. In a streptozotocin-induced diabetic nude mouse tumour xenograft model, hyperglycaemia and lack of insulin caused an increased formation of tumour-associated HA-matrix, which in turn accelerated tumour progression and neoangiogenesis...
May 10, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28493322/three-year-cancer-incidence-in-blantyre-malawi-2008-2010
#10
Steady J D Chasimpha, D Maxwell Parkin, Leo Masamba, Charles P Dzamalala
In this paper we present incidence rates of different cancers calculated for the population of Blantyre, Malawi for the period 2008-2010, using data from the Malawi Cancer Registry. Active methods were used for case finding, with standard checks for accuracy and validity performed in CanReg 4. During this three year period, a total of 3,711 cases were registered comprising 1,643 men (an estimated age-standardized incidence rate (ASR) of 169.8 per 100,000) and 2,068 women (ASR 238.7 per 10(5) ). Kaposi sarcoma (KS) was the most common cancer in men (40...
May 10, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28485362/cancer-statistics-in-kamrup-urban-district-incidence-and-mortality-in-2007-2011
#11
Jagannath Dev Sharma, Amal Chandra Kataki, Debanjana Barman, Arpita Sharma, Manoj Kalita
PURPOSE: The aim of this study was to report cancer statistics in Kamrup Urban District, including incidence and, mortality. INTRODUCTION: In the last five year PBCR-Guwahati witnessed a remarkable growth in cancer incidence cases. The number of new cases of all cancer was increased from 155.3 to 188.5 and 102.7 to 165.3 per 100,000 men and women respectively from the year 2007 to 2011 in KUD. The data from KUD also have shown that for some of the specific types of cancer are highest or some of the highest incidence in rates in the world; particularly cancers of upper aero-digestive tract consist of anatomical sites such as oral cavity, hypopharynx, larynx gallbladder, stomach, lung, prostate and oesophageal cancer...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485167/expression-and-clinicopathological-significance-of-mel-18-and-bmi-1-in-oesophageal-squamous-cell-carcinoma
#12
H J Ji, M Cao, K L Ren, N B Sun, B Xu, X T Chang, W Wang, Q Zang, Z M Jiang
The Polycomb group (PcG) genes are a general class of regulators that are responsible for maintaining homeotic gene expression throughout cell division. PcG expression plays an important role in oncogenesis of several types of human cancer. Mel-18 and Bmi-1 are key PcG proteins. Studies have shown that Mel-18 is a potential tumour suppression and Bmi-1 is overexpressed in several human malignancies. However, the roles of Mel-18 and Bmi-1 in oesophageal squamous cell carcinoma (ESCC) are still unclear. In this study, we analysed the expression levels of Mel-18 and Bmi-1 in 89 oesophageal cancer tissues and paired normal mucosal tissues using immunohistochemistry, Western blotting and quantitative real-time PCR (QRT-PCR) analyses...
May 9, 2017: Neoplasma
https://www.readbyqxmd.com/read/28475724/neoadjuvant-chemoradiotherapy-with-concurrent-cisplatin-5-fluorouracil-is-associated-with-increased-pathologic-complete-response-and-improved-survival-compared-to-carboplatin-paclitaxel-in-patients-with-locally-advanced-esophageal-cancer
#13
K R Haisley, K D Hart, N Nabavizadeh, K G Bensch, G M Vaccaro, C R Thomas, P H Schipper, J G Hunter, J P Dolan
Trimodal therapy consisting of neoadjuvant chemoradiation followed by esophagectomy has become the standard of care in North America for locally advanced esophageal cancer. While cisplatin/5-fluorouracil has been a common concurrent chemotherapy regimen since the 1980s, its utilization has declined in recent years as the Chemoradiotherapy for Oesophageal Cancer Followed by Surgery Study (CROSS) trial regimen of carboplatin/paclitaxel has become widely adopted. The efficacy of the CROSS regimen compared to alternate chemotherapy choices, however, has rarely been evaluated when each is used as a component of a trimodal treatment approach...
July 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28465312/a-comparative-analysis-of-whole-genome-sequencing-of-oesophageal-adenocarcinoma-pre-and-post-chemotherapy
#14
Ayesha Noorani, Jan Bornschein, Andy G Lynch, Maria Secrier, Achilleas Achilleos, Matthew Eldridge, Lawrence Bower, Jamie M J Weaver, Jason Crawte, Chin-Ann Ong, Nicholas Shannon, Shona MacRae, Nicola Grehan, Barbara Nutzinger, Maria O'Donovan, Richard Hardwick, Simon Tavaré, Rebecca C Fitzgerald, Rachael Fels Elliott, Paul A W Edwards, Xiaodun Li, Hamza Chettouh, Gianmarco Contini, Eleanor Gregson, Sebastian Zeki, Laura Smith, Zarah Abdullahi, Rachel de la Rue, Ahmad Miremadi, Shalini Malhotra, Mike L Smith, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Richard Turkington, Stephen J Hayes, Yeng Ang, Shaun R Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J E Skipworth, Ted R Hupp, J Robert O'Neill, Olga Tucker, Andrew Beggs, Philippe Taniere, Timothy J Underwood, Fergus Noble, Jack Owsley, Hugh Barr, Neil Shepherd, Oliver Old, Jesper Lagergren, James Gossage, Andrew Davies, Fuju Chang, Janine Zylstra, Grant Sanders, Richard Berrisford, Catherine Harden, David Bunting, Mike Lewis, Ed Cheong, Bhaskar Kumar, Simon L Parsons, Irshad Soomro, Philip Kaye, Laurence Lovat, Rehan Haidry, Victor Eneh, Laszlo Igali, Michael Scott, Shamila Sothi, Sari Suortamo, Suzy Lishman
The scientific community has avoided using tissue samples from patients that have been exposed to systemic chemotherapy to infer the genomic landscape of a given cancer. Esophageal adenocarcinoma is a heterogeneous, chemoresistant tumor for which the availability and size of pretreatment endoscopic samples are limiting. This study compares whole-genome sequencing data obtained from chemo-naive and chemo-treated samples. The quality of whole-genomic sequencing data is comparable across all samples regardless of chemotherapy status...
May 2, 2017: Genome Research
https://www.readbyqxmd.com/read/28463961/herpes-zoster-risk-after-21-specific-cancers-population-based-case-control-study
#15
Erik Hansson, Harriet J Forbes, Sinéad M Langan, Liam Smeeth, Krishnan Bhaskaran
BACKGROUND: Some malignancies are known to be associated with increased risk of herpes zoster, but little is known about how associations between cancer and subsequent zoster risk vary by cancer site, by time since cancer diagnosis, and by age. METHODS: An age-, sex-, calendar time-, and practice-matched case-control study, nested in the broadly UK representative Clinical Practice Research Datalink (CPRD) primary care database, was analysed using conditional logistic regression to estimate the association between 21 of the most common specific malignancies and subsequent zoster risk...
May 2, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28462649/postoperative-survival-following-perioperative-magic-versus-neoadjuvant-oe02-type-chemotherapy-in-oesophageal-adenocarcinoma
#16
A M Reece-Smith, J H Saunders, I N Soomro, C R Bowman, J P Duffy, P V Kaye, N T Welch, S Madhusudan, S L Parsons
The optimal management of resectable oesophageal adenocarcinoma is controversial, with many centres using neoadjuvant chemotherapy following the Medical Research Council (MRC) oesophageal working group (OE02) trial and the MRC Adjuvant Gastric Infusional Chemotherapy (MAGIC) trial. The more intensive MAGIC regimen is used primarily in gastric cancer but some also use it for oesophageal cancer. A database of cancer resections (2001-2013) provided information on survival of patients following either OE02 or MAGIC-type treatment...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28458120/discrepancies-in-the-use-of-chemotherapy-and-artificial-nutrition-near-the-end-of-life-for-hospitalised-patients-with-metastatic-gastric-or-oesophageal-cancer-a-countrywide-register-based-study
#17
Emmanuelle Kempf, Christophe Tournigand, Philippe Rochigneux, Régis Aubry, Lucas Morin
AIM: To evaluate the frequency and the factors associated with the use of chemotherapy and artificial nutrition near the end of life in hospitalised patients with metastatic oesophageal or gastric cancer. METHODS: Nationwide, register-based study, including all hospitalised adults (≥20 years) who died with metastatic oesophageal or gastric cancer between 2010 and 2013, in France. Chemotherapy and artificial nutrition during the final weeks of life were considered as primary outcomes...
April 26, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28451002/-costal-metastasis-revealing-esophageal-squamous-cell-carcinoma
#18
Mamadou Ngoné Gueye, Gnagna Diouf, Daouda Dia, Awa Boye, Thierno Fall, Jean Louis Diémé, Oumar Ba, Mouhamadou Mbengue
Esophageal cancer is associated with poor prognosis. Its severity is linked to delayed diagnosis which is most often made once a cancer has metastasized, in Africa. Costal metastases are rare. We report a case of a 38-year old Senegalese patient with squamous cell carcinoma of the lower esophagus with lytic metastases to the ribs. Mrs. TD, aged 38, was admitted with painful swelling in right hemithorax associated with weight loss. The patient also reported mechanical dysphagia evolving during 4 months which had not motivated consultation...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28449053/fresh-fruit-consumption-and-all-cause-and-cause-specific-mortality-findings-from-the-china-kadoorie-biobank
#19
Huaidong Du, Liming Li, Derrick Bennett, Ling Yang, Yu Guo, Timothy J Key, Zheng Bian, Yiping Chen, Robin G Walters, Iona Y Millwood, Junshi Chen, Junzheng Wang, Xue Zhou, Le Fang, Yijun Li, Xianzhi Li, Rory Collins, Richard Peto, Zhengming Chen
Background: Higher fruit consumption is associated with lower risk of cardiovascular disease (CVD). Substantial uncertainties remain, however, about the associations of fruit consumption with all-cause mortality and mortality from subtypes of CVD and major non-vascular diseases, especially in China. Methods: In 2004-08, the nationwide China Kadoorie Biobank Study recruited > 0.5 million adults aged 30-79 years from 10 diverse localities in China. Fresh fruit consumption was estimated using an interviewer-administered electronic questionnaire, and mortality data were collected from death registries...
April 24, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28447567/a-longitudinal-assessment-of-psychological-distress-after-oesophageal-cancer-surgery
#20
Ylva Hellstadius, Jesper Lagergren, Janine Zylstra, James Gossage, Andrew Davies, Christina M Hultman, Pernilla Lagergren, Anna Wikman
BACKGROUND: Psychological distress is common among patients with oesophageal cancer. However, little is known about the course and predictors of psychological distress among patients treated with curative intent. Therefore, the aim of this study was to explore the prevalence, course and predictors of anxiety and depression in patients operated for oesophageal cancer, from prior to surgery to 12 months post-operatively. METHODS: A prospective cohort of patients with oesophageal cancer (n = 218) were recruited from one high-volume specialist oesophago-gastric treatment centre (St Thomas' Hospital, London, UK)...
May 2017: Acta Oncologica
keyword
keyword
40066
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"