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Kajsa Fritzell, Li-Di Xu, Jens Lagergren, Marie Öhman
Cancer arises when pathways that control cell functions such as proliferation and migration are dysregulated to such an extent that cells start to divide uncontrollably and eventually spread throughout the body, ultimately endangering the survival of an affected individual. It is well established that somatic mutations are important in cancer initiation and progression as well as in creation of tumor diversity. Now also modifications of the transcriptome are emerging as a significant force during the transition from normal cell to malignant tumor...
November 16, 2017: Seminars in Cell & Developmental Biology
Shuanghu Tiger Yuan, Richard K J Brown, Lujun Zhao, Randall K ten Haken, Milton Gross, Kemp B Cease, Matt Schipper, Paul Stanton, Jinming Yu, Feng-Ming Spring Kong
PURPOSE: To study whether esophageal FDG activity changes by time of mid-course of fractionated radiotherapy (RT), and whether these changes are associated with radiation esophagitis in patients with non-small cell lung cancer (NSCLC). METHODS: Fifty patients with stage I-III NSCLC were enrolled prospectively and, all received ≥60 Gy RT. FDG-PET/CT scans were acquired prior to, and during-RT after delivery of 45 Gy. Normalized standardized uptake values (NSUV), defined by the esophageal maximum SUV relative to intravascular background level in the aortic arch, were sampled in the esophagus at the level of the primary tumor, sternal notch, aortic arch, carina, and gastro-esophageal junction...
January 27, 2014: Radiation Oncology
Simon J Davies, Simran Minhas, R Jonathan T Wilson, David Yates, Simon J Howell
STUDY OBJECTIVE: To compare stroke volume (SV) and preload responsiveness measurements from different technologies with the esophageal Doppler monitor (EDM). DESIGN: Prospective measurement study. SETTING: Operating room. PATIENTS: 20 ASA physical status 3 patients undergoing vascular, major urological, and bariatric surgery. INTERVENTIONS: Subjects received fluids using a standard Doppler protocol of 250 mL of colloid administered until SV no longer increased by >10%, and again when the measured SV decreased by 10%...
September 2013: Journal of Clinical Anesthesia
No abstract text is available yet for this article.
June 1955: A.M.A. Archives of Otolaryngology
M Tagle Arróspide, M Aguinaga Meza, G Vásquez Rubio
AIM: To describe the endoscopic findings in adult patients subjected to esophagogastroduodenoscopy (EGD) for the evaluation of heartburn, and establish a relationship between the presence of a hiatal hernia and erosive esophagitis. PATIENTS AND METHODS: We reviewed the endoscopic reports of all the patients older than 16 years old who were evaluated for heartburn in our institution, between December 1998 and December 2001. The statistical analysis to establish the relationship between Hiatal Hernia (HH) and Erosive Esophagitis (EE) was performed calculating the Odds Ratio (OR)...
January 2003: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
W Shen, Y Sun
OBJECTIVE: To investigate the relation between Deficiency Syndrome (DS) of TCM and the invading depth, lymphnode metastasis, TNM stage and prognosis prediction of esophageal carcinoma. METHODS: According to Syndrome Differentiation of TCM, 101 patients of esophageal carcinoma were evaluated before operation and divided into two groups, the DS group and the non-DS group. RESULTS: Thirty-eight cases in the 101 patients were DS, among them, 14 were Qi-Deficiency, 10 Yin-Deficiency, 10 Qi-Yin Deficiency, 2 Qi- and blood Deficiency, 1 Yang-Deficiency and 1 Yin-Yang Deficiency...
February 1999: Chinese Journal of Integrated Traditional and Western Medicine
J Galizzi-Filho, M de O Andrade, M de M Cota, F J Penna, P P Figueiredo-Filho, C A Valadares, R Machado-Silva, J Barquete, J P de Oliveira, J A de Almeida
Brazil has a young population and areas of endemic mansoni schistosomiasis where Wilson's disease might be easily misdiagnosed in patients erroneously classified as having either the hepatosplenic or the hepatointestinal form of the helminthiasis. Twenty five patients with the "hepatic form" of Wilson's disease (14 males and 11 females) were investigated in Belo Horizonte, MG; the mean age was 13.7 years (3 to 22). Nineteen had hepatomegaly (76%) and nine splenomegaly (36%). Twenty two (88%) had cirrhosis. The Kaiser-Fleisher ring was detected in fifteen (60%)...
January 1998: Arquivos de Gastroenterologia
J H Hegarty, L Halvorsen, B P Hazenberg, A Nowak, C L Smith, A B Thomson, G Vantrappen, C J McKenna, J G Mills
OBJECTIVE: To compare the efficacy and safety of long term use of ranitidine 150 mg bid, 300 mg bid and placebo in prevention of endoscopic and symptomatic relapse of reflux esophagitis in an international, double-blind, placebo controlled, parallel group study. PATIENTS AND METHODS: A total of 279 patients at least 18 years old from hospital out-patient departments with healed esophagitis (grade 0) with no or mild symptoms entered the study. Patients were randomly allocated to receive ranitidine 150 mg, 300 mg placebo twice daily for 48 weeks...
January 1997: Canadian Journal of Gastroenterology, Journal Canadien de Gastroenterologie
A Ruiz de León, M C Sevilla-Mantilla, J Pérez de la Serna, C Taxonera, J García-Cabezas, M Díaz-Rubio
Two-level pH monitoring was performed for 24 hours in 20 healthy subjects to document the presence of reflux episodes and to obtain reference values for reflux studies. The pH probes were placed 5 and 20 centimetres above the LES by means of a manometric technique. Significant differences were found at these two levels. At the proximal esophageal level 18 of the 20 subjects had reflux episodes. Five centrimetres above the lower esphageal sphincter the total reflux time was 1.35%, 2.05% in the upright and 0...
December 1994: Revista Española de Enfermedades Digestivas
G Salis, F Lazaroni, J C Chiocca, P A Mazure, A Sferco
In the present study 39 patients with benign esphageal stenosis were studied (average age 59,9 years). The most common etiology was refux esofagitis, and the most common associated pathology was esophageal hiatus hernia. Thirty one patients received medical treatment (diet. antireflux drugs and dilatations.) Twenty four were dilated with the slow continuous method, six with metalic bougies. One patient was not dilated. Seven patients were not treated since the stenosis was due to extrinsec compression. One patient was surgically treated from the onset...
September 1978: Acta Gastroenterologica Latinoamericana
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