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chromium diabetes

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https://www.readbyqxmd.com/read/28733937/sequential-extraction-as-novel-approach-to-compare-12-medicinal-plants-from-kenya-regarding-their-potential-to-release-chromium-manganese-copper-and-zinc
#1
R Mogwasi, S Zor, D K Kariuki, M Z Getenga, V Nischwitz
This study is focusing on a novel approach to screen a large number of medicinal plants from Kenya regarding their contents and availability of selected metals potentially relevant for treatment of diabetes patients. For this purpose, total levels of zinc, chromium, manganese, and copper were determined by flame atomic absorption spectrometry and inductively coupled plasma mass spectrometry as well as BCR sequential extraction to fractionate the elemental species in anti-diabetic medicinal plants collected from five natural locations in two sub counties in Nyamira County, Kenya...
July 21, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28677892/chromium-supplementation-for-adjuvant-treatment-of-type-2-diabetes-mellitus-results-from-a-pooled-analysis
#2
Haohai Huang, Guangzhao Chen, Yong Dong, Yongkun Zhu, Honglang Chen
SCOPE: We conducted a pooled analysis of randomized controlled trials to evaluate the effects of chromium supplementation on clinically relevant metabolic biomarkers in type 2 diabetes mellitus (T2DM) patients. METHODS AND RESULTS: Electronic searches were conducted and the bibliographies of located articles were searched, and 28 studies were suitable for statistical pooling. Endpoints were calculated as weighted mean differences (WMDs) with 95% confidence intervals (CIs) by using fixed-effects or random-effects models...
July 5, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28643849/prevalence-of-exposure-of-heavy-metals-and-their-impact-on-health-consequences
#3
Kanwal Rehman, Fiza Fatima, Iqra Waheed, Muhammad Sajid Hamid Akash
Even in the current era of growing technology, the concentration of heavy metals present in drinking water is still not within the recommended limits as set by the regulatory authorities in different countries of the world. Drinking water contaminated with heavy metals namely; arsenic, cadmium, nickel, chromium, mercury, chromium, zinc and lead is becoming a major health concern for public and health care professionals. Occupational exposure to heavy metals is known to occur by the utilization of these metals in various industrial processes and/or contents including color pigments and alloys...
June 23, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28640307/healthy-properties-of-green-and-white-teas-an-update
#4
REVIEW
S Pastoriza, M Mesías, C Cabrera, J A Rufián-Henares
Green tea has been consumed for centuries in Japan, China and Morocco. White tea, which is considered a variety of green tea, is mostly consumed in China and is very appreciated for its flavor. Currently the consumption of both types of tea has been extended to the western countries even as a functional ingredient. A group of polyphenols called catechins stands out among their bioactive components, the most abundant being the (-) epigallocatechin gallate, with high antioxidant power. Teas also contain other phenolic compounds such as gallic, caffeic, chlorogenic or cinnamic acids, quercetin and proanthocyanidols, caffeine, theophylline, l-theanine and minerals such as fluorine, manganese or chromium...
June 22, 2017: Food & Function
https://www.readbyqxmd.com/read/28632927/prospective-associations-between-environmental-heavy-metal-exposure-and-renal-outcomes-in-adults-with-chronic-kidney-disease
#5
Chun-Chieh Tsai, Chia-Lin Wu, Chew-Teng Kor, Ie-Bin Lian, Chin-Hua Chang, Teng-Hsiang Chang, Chia-Chu Chang, Ping-Fang Chiu
BACKGROUND: In Taiwan, Changhua County residents were exposed to high heavy metal pollution and exhibited high heavy metal levels in blood and urine. We examined associations between heavy metals in residential soil and renal outcomes of residents with chronic kidney disease (CKD). METHOD: From January 01, 2003 to June 30, 2015, we retrospectively identified CKD patients with an estimated glomerular filtration rate of <60 mL/min/1.73 m(2) at one tertiary care center...
June 20, 2017: Nephrology
https://www.readbyqxmd.com/read/28531788/association-of-dietary-factors-with-severity-of-coronary-artery-disease
#6
Namita Mahalle, M K Garg, S S Naik, M V Kulkarni
BACKGROUND: Cardiovascular disease has taken epidemic proportions during past decades. Cardiovascular risk factors contribute to progression of coronary lesions, worsening the patient's prognosis. This study was planned to analyze the association of dietary factors with severity of coronary artery disease (CAD) in Indian patients. METHODS: Three hundred patients with known coronary disease above the age of 25 years were included in this study. Blood samples were collected for biochemical markers...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28516390/the-identity-of-chromium-malate
#7
Megan Smart, Silas Brown, Haley Tannehill, Molly Lockart, Michael K Bowman, John B Vincent
Recently, several studies on the effects of a compound named "chromium malate," with the proposed formula "Cr2malate3·xH2O" where x = 3.5 or 5, on the health of healthy and diabetic rats have appeared. However, the compound is poorly characterized, and knowing the identity of this material could be important in the interpretation of the previous and of future studies on the effects of this compound in animals. Consequently, the synthesis, characterization, and identity of this material were explored. A combination of spectroscopic, magnetic, and elemental analyses and mass spectral studies reveal that the compound is probably a polymer, not a discrete molecule, and does not have the composition previously reported...
May 18, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28506761/the-decline-in-kidney-function-with-chromium-exposure-is-exacerbated-with-co-exposure-to-lead-and-cadmium
#8
Tsung-Lin Tsai, Chin-Chi Kuo, Wen-Harn Pan, Yu-Teh Chung, Chiu-Ying Chen, Trong-Neng Wu, Shu-Li Wang
Environmental factors contribute significantly to the pathogenesis of chronic kidney disease. However, these factors, and particularly the toxic effects of heavy metals, have not been completely evaluated. Chromium is a widespread industrial contaminant that has been linked to nephrotoxicity in animal and occupational population studies. Nevertheless, its role in population renal health and its potential interactions with other nephrotoxic metals, such as lead and cadmium, remain unknown. We assessed the association between exposure to chromium, lead, and cadmium with renal function using estimated glomerular filtration rate (eGFR) in an analysis of 360 Taiwanese adults aged 19-84 years from the National Nutrition and Health Survey in Taiwan (2005-2008)...
May 12, 2017: Kidney International
https://www.readbyqxmd.com/read/28416368/nutritional-management-in-women-with-polycystic-ovary-syndrome-a-review-study
#9
REVIEW
Zeinab Faghfoori, Siavash Fazelian, Mahdi Shadnoush, Reza Goodarzi
Polycystic ovary syndrome (PCOS) is endocrine disorder in women of reproductive age, which leads to reproductive, hormonal and metabolic abnormalities. Due to the presence of insulin resistance, PCOS increases the risk of chronic diseases like type 2 diabetes, hypertension, lipid disorders, cardiovascular diseases and malignancies such as breast and endometrial cancer. The actual cause of this syndrome is unknown but environmental factors such as dietary habits play an important role in prevention and treatment and lifestyle modifications are the most important therapeutic strategies in these patients...
April 5, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28409409/hypoglycemic-and-hypolipidemic-effects-of-leucine-zinc-and-chromium-alone-and-in-combination-in-rats-with-type-2-diabetes
#10
Hassan Sadri, Negar Nowroozi Larki, Saeed Kolahian
For the increasing development of diabetes, dietary habits and using appropriate supplements can play important roles in the treatment or reduction of risk for this disease. The objective of this study was to investigate the effects of leucine (Leu), zinc (Zn), and chromium (Cr) supplementation, alone or in combination, in rats with type 2 diabetes (T2D). Seventy-seven adult male Wistar rats were randomly assigned in 11 groups, using nutritional supplements and insulin (INS) or glibenclamide (GLC). Supplementing Leu significantly reduced blood glucose, triglycerides (TG), nonesterified fatty acids (NEFA), low-density lipoprotein (LDL), and increased high-density lipoprotein (HDL) concentrations compared to vehicle-treated T2D animals, and those improvements were associated with reduced area under the 2-h blood glucose response curve (AUC)...
April 13, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28392547/chromium-exposure-and-risk-of-cardiovascular-disease-in-high-cardiovascular-risk-subjects%C3%A3-nested-case-control-study-in-the-prevention-with-mediterranean-diet-predimed-study
#11
Mario Gutiérrez-Bedmar, Miguel Ángel Martínez-González, Carlos Muñoz-Bravo, Miguel Ruiz-Canela, Alberto Mariscal, Jordi Salas-Salvadó, Ramón Estruch, Dolores Corella, Fernando Arós, Monserrat Fito, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Ángel Alonso-Gómez, Olga Portoles, Miquel Fiol, Mónica Bulló, Olga Castañer, Emilio Ros, Enrique Gómez-Gracia
BACKGROUND: Epidemiological data on chromium (Cr) exposure and the risk of cardiovascular disease (CVD) are still limited. Toenail Cr level (TCL) provides a time-integrated measure reflecting long-term Cr exposure. We measured TCL to assess the hypothesis that long-term Cr exposure was inversely associated with incident CVD in a population at high risk for CVD.Methods and Results:The associations between TCL and CVD were evaluated in a case-control study nested within the "PREvención con DIeta MEDiterránea" (PREDIMED) trial...
April 8, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28385356/the-promus-premier-everolimus-eluting-platinum-chromium-stent-with-durable-polymer-evaluated-in-a-real-world-all-comer-population-in-rotterdam-cardiology-hospital-the-p-search-registry
#12
Miguel E Lemmert, Nicolas M van Mieghem, Robert-Jan van Geuns, Roberto Diletti, Rutger J van Bommel, Ron T van Domburg, Peter P de Jaegere, Evelyn Regar, Felix Zijlstra, Eric Boersma, Joost Daemen
BACKGROUND: A new-generation everolimus eluting platinum-chromium stent (EePCS), offering improved radial strength, radiopacity and conformability compared to everolimus-eluting cobalt-chromium stents (EeCCS), was evaluated with regard to safety and efficacy in an all-comer cohort. METHODS: A total of 1000 consecutive all-comer patients (including acute coronary syndrome, multivessel disease, calcified lesions) treated with an EePCS (Promus Premier™, Boston Scientific, Natick, Massachusetts) from May 2013 to October 2014 were compared to 1000 consecutive patients treated with an EeCCS (Xience Prime™, Abbott Vascular, Santa Clara, California) from April 2012 to May 2013...
March 20, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28347468/trace-element-status-in-patients-with-type-2-diabetes-in-norway-the-hunt3-survey
#13
Anica Simić, Ailin Falkmo Hansen, Bjørn Olav Åsvold, Pål Richard Romundstad, Kristian Midthjell, Tore Syversen, Trond Peder Flaten
Several epidemiological studies have indicated that a number of trace elements may play a role in type 2 diabetes (T2D). We investigated the association between prevalent T2D and the concentrations of 25 trace elements in whole blood, and the relationships between T2D duration and blood levels of the trace elements that we found to be related to T2D prevalence. In this population based case-control study, 267 patients with self-reported T2D and 609 controls (frequency matched), were selected from the third Nord-Trøndelag Health Survey...
May 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28345659/oral-chromium-picolinate-impedes-hyperglycemia-induced-atherosclerosis-and-inhibits-proatherogenic-protein-tsp-1-expression-in-stz-induced-type-1-diabetic-apoe-mice
#14
Rituparna Ganguly, Soumyadip Sahu, Vahagn Ohanyan, Rebecca Haney, Ronaldo J Chavez, Shivani Shah, Siri Yalamanchili, Priya Raman
Increasing evidence suggests thrombospondin-1 (TSP-1), a potent proatherogenic matricellular protein, as a putative link between hyperglycemia and atherosclerotic complications in diabetes. We previously reported that the micronutrient chromium picolinate (CrP), with long-standing cardiovascular benefits, inhibits TSP-1 expression in glucose-stimulated human aortic smooth muscle cells in vitro. Here, we investigated the atheroprotective action of orally administered CrP in type 1 diabetic apolipoprotein E-deficient (ApoE(-/-)) mice and elucidated the role of TSP-1 in this process...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28304331/inverse-association-of-plasma-chromium-levels-with-newly-diagnosed-type-2-diabetes-a-case-control-study
#15
Sijing Chen, Xiaoling Jin, Zhilei Shan, Shuzhen Li, Jiawei Yin, Taoping Sun, Cheng Luo, Wei Yang, Ping Yao, Kaifeng Yu, Yan Zhang, Qian Cheng, Jinquan Cheng, Wei Bao, Liegang Liu
Chromium has long been known as an enhancer of insulin action. However, the role of chromium in the development of type 2 diabetes mellitus (T2DM) in humans remains controversial. The current study aimed to examine the associations of plasma chromium levels with T2DM and pre-diabetes mellitus (pre-DM). We conducted a case-control study involving 1471 patients with newly diagnosed T2DM, 682 individuals with newly diagnosed pre-DM, and 2290 individuals with normal glucose tolerance in a Chinese population from 2009 to 2014...
March 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28281224/the-effects-of-supplementary-cr3-chromium-iii-propionate-complex-on-the-mineral-status-in-healthy-female-rats
#16
Halina Staniek, Zbigniew Krejpcio
More and more people use food supplements for various reasons, e.g. to prevent mineral deficiency and diseases (e.g. osteoporosis, diabetes, anaemia). Supplements containing Cr(III) are purchased primarily for weight loss and antidiabetic effects. The aim of this study was to evaluate the effects of supplementary Cr3 {chromium(III) propionate complex, [Cr3O(O2CCH2CH3)6(H2O)3]NO3)} on the mineral status in female Wistar rats. The study was carried out on 30 female Wistar rats, divided into five groups (six animals in each): a control group and test groups fed Cr3 supplemented diets with 100, 200, 500 and 1000 mg Cr · kg(-1) diet (equivalent to 10, 20, 50 and 100 mg Cr ·kg(-1) body mass (b...
March 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28197835/selenium-vanadium-and-chromium-as-micronutrients-to-improve-metabolic-syndrome
#17
REVIEW
Sunil K Panchal, Stephen Wanyonyi, Lindsay Brown
Trace metals play an important role in the proper functioning of carbohydrate and lipid metabolism. Some of the trace metals are thus essential for maintaining homeostasis, while deficiency of these trace metals can cause disorders with metabolic and physiological imbalances. This article concentrates on three trace metals (selenium, vanadium, and chromium) that may play crucial roles in controlling blood glucose concentrations possibly through their insulin-mimetic effects. For these trace metals, the level of evidence available for their health effects as supplements is weak...
March 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28159221/trace-elements-in-early-phase-type-2-diabetes-mellitus-a-population-based-study-the-hunt-study-in-norway
#18
Ailin Falkmo Hansen, Anica Simić, Bjørn Olav Åsvold, Pål Richard Romundstad, Kristian Midthjell, Tore Syversen, Trond Peder Flaten
Differences in trace elements levels between individuals with type 2 diabetes and controls have been reported in several studies in various body fluids and tissues, but results have been inconsistent. In order to examine trace element levels in the early phase of type 2 diabetes, we investigated the association between whole blood levels of 26 trace elements and the prevalence of previously undiagnosed, screening-detected type 2 diabetes. The study was conducted as a case-control study nested within the third survey of the population-based Nord-Trøndelag Health Study (HUNT3 Survey)...
March 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28087233/anti-diabetic-effects-of-inonotus-obliquus-polysaccharides-chromium-iii-complex-in-type-2-diabetic-mice-and-its-sub-acute-toxicity-evaluation-in-normal-mice
#19
Cong Wang, Zhongqin Chen, Yuxiang Pan, Xudong Gao, Haixia Chen
Polysaccharides are important bioactive ingredients from Inonotus obliquus. This study aimed to synthesize and characterize a novel I. obliquus polysaccharides-chromium (III) complex (UIOPC) and investigate the anti-diabetic effects in streptozotocin (STZ) induced type 2 diabetes mellitus (T2DM) mice and sub-acute toxicity in normal mice. The molecular weight of UIOPC was about 11.5 × 10 (4) Da with the chromium content was 13.01% and the chromium was linked with polysaccharides through coordination bond...
January 11, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28072825/dietary-chromium-restriction-of-pregnant-mice-changes-the-methylation-status-of-hepatic-genes-involved-with-insulin-signaling-in-adult-male-offspring
#20
Qian Zhang, Xiaofang Sun, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Zhixin Wang, Cuijuan Qi, Tong Wang, Xiaojing Wang
Maternal undernutrition is linked with an elevated risk of diabetes mellitus in offspring regardless of the postnatal dietary status. This is also found in maternal micro-nutrition deficiency, especial chromium which is a key glucose regulator. We investigated whether maternal chromium restriction contributes to the development of diabetes in offspring by affecting DNA methylation status in liver tissue. After being mated with control males, female weanling 8-week-old C57BL mice were fed a control diet (CON, 1...
2017: PloS One
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