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https://www.readbyqxmd.com/read/29457946/the-provision-of-ambulatory-systemic-anti-cancer-therapy
#1
Susan Cooper, Kate de Lord
This article reflects on the changing nature of the provision of care and delivery of ambulatory systemic anti-cancer therapy (SACT) services. It reviews the national guidance and looks at ambulatory SACT in terms of patients being treated closer to home, i.e. ambulatory care in its truest sense. It considers the impact on quality of life for patients receiving treatments at a place of their choice. It explores the role of the nurse as an advanced practitioner while also examining the safety and delivery of complex regimens ensuring robust pathways are in place to deliver care in a safe and standardised way...
February 22, 2018: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29457919/enterobacteriaceae-antibiotic-resistance-in-ready-to-eat-foods-collected-from-hospital-and-community-canteens-analysis-of-prevalence
#2
Sara Vincenti, Matteo Raponi, Romina Sezzatini, Gabriele Giubbini, Patrizia Laurenti
Foodborne diseases and antibiotic resistance are serious widespread health problems in the contemporary world. In this study, we compared the microbiological quality of ready-to-eat (RTE) foods found in community canteens versus hospital canteens in Rome, Italy, focusing on detection and quantification of Enterobacteriaceae and the antibiotic resistance of these bacteria. Our findings show a remarkable difference in Enterobacteriaceae contamination between RTE foods distributed in community canteens (33.5% of samples) and those distributed in hospital canteens (5...
February 19, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29457627/combination-pharmacotherapy-for-the-treatment-of-fibromyalgia-in-adults
#3
REVIEW
Joelle Thorpe, Bonnie Shum, R Andrew Moore, Philip J Wiffen, Ian Gilron
BACKGROUND: Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide. Current pharmacotherapies are often ineffective and poorly tolerated. Combining different agents could provide superior pain relief and possibly also fewer side effects. OBJECTIVES: To assess the efficacy, safety, and tolerability of combination pharmacotherapy compared to monotherapy or placebo, or both, for the treatment of fibromyalgia pain in adults. SEARCH METHODS: We searched CENTRAL, MEDLINE, and Embase to September 2017...
February 19, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29457467/civil-forensic-psychiatry-part-3-practical-aspects-of-managing-a-medico-legal-practice
#4
Anthony H Samuels
OBJECTIVES: This is the third in a series of papers on Civil Forensic Psychiatry and provides practical advice for forensic psychiatrists, general psychiatrists and trainees who are expanding or contemplating a medico-legal aspect to their practice. CONCLUSIONS: Attention to the practice setting, office layout, recording of information, management of documentation, screening of briefs and proper timetabling can improve safety, quality, reliability and workload manageability...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29457434/-minimally-invasive-sinus-tarsal-approach-versus-conventional-l-shaped-lateral-approach-in-treating-calcaneal-fractures-a-meta-analysis
#5
Min-Hao Wu, Wen-Chao Sun, Fei-Fei Yan, Zhi-Qiang Hou, Fan Feng, Lin Cai
OBJECTIVE: To compare efficacy and safety of minimally invasive sinus tarsal approach versus conventional L-shaped lateral approach in treating calcaneal fractures. METHODS: The studies concerning about randomized controlled trial and non-randomized controlled trial of minimally invasive sinus tarsal approach versus conventional L-shaped lateral approach in treating calcaneal fractures from the time of creating database to March, 2017 were searched from PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), EMbase, ISI Web of Knowledge databases, VIP, CNKI, CBM and Wan Fang...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457416/-meta-analysis-of-the-efficacy-and-safety-of-pfna-and-intertan-for-the-treatment-of-intertrochanteric-fractures
#6
Jun-Jun Shi, Yu-Ze Wang, Yuan Li, Yuan-Peng Gao, Dong Wang, Zhi-Yong Wang, Zhi-Qiang Zhang
OBJECTIVE: To system evaluate the clinical effect and safety of PFNA and InterTAN internal fixation methods for femoral intertrochanteric fracture. METHODS: According to the Cochrane systemic analysis method, randomized controlled trials and quasi-randomized controlled trials which were about the comparison of PFNA and InterTAN for intertrochanteric fracture were collected from Cochrane Library(2017, issue 4), PubMed (January, 2003-May, 2017), Wanfang Med Online (January, 2003-May, 2017) and China Academic Journals Full-text Database(January, 2003-May, 2017) by computer searching...
October 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29457248/duty-hours-restriction-for-our-surgical-trainees-an-ethical-obligation-or-a-bad-idea
#7
REVIEW
Christopher A Adin, Callie A Fogle, Steven L Marks
To ensure patient safety and protect the well-being of interns and residents, the Accreditation Council for Graduate Medical Education (ACGME) issued guidelines in 2003 limiting the working hours of physician trainees. Although many supported the goals of the ACGME, institutions struggled to restructure their programs and hire staff required by this unfunded mandate. Numerous studies have analyzed the effects of duty hours restrictions on patient outcomes and physician training over the past 15 years. Most agree that duty hours restrictions improved well-being of house officers, but these improvements came at the expense of continuity, and patient hand-offs led to medical errors...
February 19, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29457216/n-acetylcysteine-for-major-mental-disorders-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#8
W Zheng, Q-E Zhang, D-B Cai, X-H Yang, Y Qiu, G S Ungvari, C H Ng, M Berk, Y-P Ning, Y-T Xiang
OBJECTIVE: This systematic review and meta-analysis of randomized controlled trials (RCTs) examined the efficacy and safety of adjunctive N-acetylcysteine (NAC), an antioxidant drug, in treating major depressive disorder (MDD), bipolar disorder, and schizophrenia. METHODS: The PubMed, Cochrane Library, PsycINFO, CNKI, CBM, and WanFang databases were independently searched and screened by two researchers. Standardized mean differences (SMDs), risk ratios, and their 95% confidence intervals (CIs) were computed...
February 18, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29456918/cervical-disc-arthroplasty-a-comprehensive-review-of-single-level-multilevel-and-hybrid-procedures
#9
REVIEW
Joseph L Laratta, Jamal N Shillingford, Comron Saifi, K Daniel Riew
Study Design: Systematic review. Objectives: Degenerative disc disease and spondylosis resulting in radiculopathy and retrodiscal myelopathy are among the most frequently encountered cervical spinal disorders. Traditionally, anterior cervical discectomy and fusion (ACDF) has successfully achieved neural decompression and restored intradiscal height in these conditions. Unfortunately, nonunion and iatrogenic adjacent segment pathology associated with fusion procedures in the cervical spine has led to an interest in motion-preserving procedures...
February 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29456840/mixed-methods-evaluation-of-the-impact-of-a-short-term-training-program-on-sterile-processing-knowledge-practice-and-attitude-in-three-hospitals-in-benin
#10
Olive Fast, Christina Fast, Dan Fast, Suzanne Veltjens, Zouliha Salami, Michelle White
Background: Proper sterile processing is fundamental to safe surgical practice and optimal patient outcomes. Sterile processing practices in low and middle-income countries often fall short of recommended standards. The impact of education and training on sterile processing practices in low and middle-income countries is unknown. We designed a sterile processing education course, including mentoring, and aimed to evaluate the impact on participants' personal knowledge, skills, and practices...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29456506/therapeutic-effects-of-a-traditional-chinese-medicine-formula-plus-tamoxifen-vs-tamoxifen-for-the-treatment-of-mammary-gland-hyperplasia-a-meta-analysis-of-randomized-trials
#11
REVIEW
Hao-Tian Li, Hong-Hong Liu, Yu-Xue Yang, Tao Wang, Xue-Lin Zhou, Yang Yu, Su-Na Li, Yi Zheng, Ping Zhang, Rui-Lin Wang, Jian-Yu Li, Shi-Zhang Wei, Kun Li, Peng-Yan Li, Li-Qi Qian
As a common disorder that accounts for over 70% of all breast disease cases, mammary gland hyperplasia (MGH) causes a severe problem for the quality of patients' life, and confers an increased risk of breast carcinoma. However, the etiology and pathogenesis of MGH remain unclear, and the safety and efficacy of current western drug therapy for MGH still need to be improved. Therefore, a meta-analysis was conducted by our team to determine whether a TCM formula named Ru-Pi-Xiao in combination with tamoxifen or Ru-Pi-Xiao treated alone can show more prominent therapeutic effects against MGH with fewer adverse reactions than that of tamoxifen...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29456468/psychosocial-aspects-of-immediate-versus-delayed-breast-reconstruction
#12
REVIEW
Anne-Sophie Heimes, Kathrin Stewen, Annette Hasenburg
Background: Only little is known about the psychosocial aspects of breast cancer patients after mastectomy with immediate versus delayed breast reconstruction. Methods: We systematically screened PubMed using the following key words: mastectomy, immediate vs. delayed reconstruction, psychosocial aspects and quality of life. To highlight different psychological outcomes, studies were categorized into those describing: anxiety, depression, body image and satisfaction with the surgical outcome...
December 2017: Breast Care
https://www.readbyqxmd.com/read/29456450/survey-on-patient-safety-culture-in-the-republic-of-moldova-a-baseline-study-in-three-healthcare-settings
#13
Carmen Tereanu, Giuseppe Sampietro, Francesco Sarnataro, Dumitru Siscanu, Rodica Palaria, Victor Savin, Tatiana Cliscovscaia, Valentina Pislaru, Valeriu Oglinda, Larisa Capmare, Mugurel Stefan Ghelase, Tamara Turcanu
Background and aims: The Republic of Moldova is a small ex-soviet country in the Central Eastern European group of states, whose official language is Romanian. In countries with limited resources, quality improvement in healthcare and patient safety are very challenging. This study aims to identify which areas of the patient safety culture (PSC) need prompt intervention. Methods: A cross-sectional study was conducted in three Moldovan healthcare settings, using the Romanian translation of the US Hospital Survey on Patient Safety Culture HSOPSC...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29456386/perception-of-patient-safety-culture-among-health-care-providers-in-a-tertiary-care-hospital-south-india
#14
Adhisakthi Rajalatchumi, Thanjavur S Ravikumar, Kaliaperumal Muruganandham, Mahalakshmy Thulasingam, Kalaiselvi Selvaraj, Mahendra M Reddy, Balachander Jayaraman
Introduction: Patient safety is a global concern and is the most important domains of health-care quality. Medical error is a major patient safety concern, causing increase in health-care cost due to mortality, morbidity, or prolonged hospital stay. Aim: The aim of the study was to assess the perceptions on patient safety culture among health-care providers (HCPs) at a public sector tertiary care hospital in South India. Settings and Design: A hospital-based cross-sectional study was conducted 1 year after patient safety initiatives were implemented...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29456375/assessment-of-queries-received-by-the-drug-information-center-at-king-saud-medical-city
#15
Dlal Abdulrahman Almazrou, Sheraz Ali, Jasser Ali Alzhrani
Background: The complexity of drug therapies has increased the need to evaluate the drug information scientifically. In this regard, the aim of drug information centers (DICs) is to promote rational use of drugs in a health-care setting. DI pharmacists play a vital role in providing the necessary and reliable information on drugs to promote the concept of rational drug use, eventually leading to a better patient outcome. The objective of the present study was to assess the drug-related queries received by the DIC at the King Saud Medical City (KSMC) from health-care professionals working in a large tertiary care setting...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29456276/effects-of-natural-antimicrobials-with-modified-atmosphere-packaging-on-the-growth-kinetics-of-listeria-monocytogenes-in-ravioli-at-various-temperatures
#16
Eun Young Ro, Geun Su Kim, Do Young Kwon, Young Min Park, Sang Woo Cho, Sang Yun Lee, Ik Hyun Yeo, Ki Sun Yoon
The objective of this study was to investigate the antimicrobial effects of cultured sugar/vinegar (CSV) blend and nisin to control the risk of Listeria monocytogenes in ready to cook (RTC) ravioli. Ravioli dough was prepared with 0.1, 0.3, 0.5, 1% CSV blend and 0.1, 0.2, and 0.3% nisin. Inoculated spinach or artichoke raviolis with 2.0 ± 0.5 log cfu/g of L. monocytogenes were packed aerobically or using modified atmosphere packaging (MAP), and then stored at 4, 10, 17, and 24 °C for 60 days. Growth kinetic parameters of the observed data fit well to the Baranyi equation...
February 2018: Journal of Food Safety
https://www.readbyqxmd.com/read/29456173/-failure-mode-and-effects-analysis-to-improve-quality-in-clinical-trials
#17
M Mañes-Sevilla, M B Marzal-Alfaro, R Romero Jiménez, A Herranz-Alonso, M N Sanchez Fresneda, J Benedi Gonzalez, M Sanjurjo-Sáez
INTRODUCTION: The failure mode and effects analysis (FMEA) has been used as a tool in risk management and quality improvement. The objective of this study is to identify the weaknesses in processes in the clinical trials area, of a Pharmacy Department (PD) with great research activity, in order to improve the safety of the usual procedures. METHODS: A multidisciplinary team was created to analyse each of the critical points, identified as possible failure modes, in the development of clinical trial in the PD...
February 15, 2018: Revista de Calidad Asistencial: Organo de la Sociedad Española de Calidad Asistencial
https://www.readbyqxmd.com/read/29455902/online-social-network-response-to-studies-on-antidepressant-use-in-pregnancy
#18
Simone N Vigod, Ebrahim Bagheri, Fattane Zarrinkalam, Hilary K Brown, Muhammad Mamdani, Joel G Ray
BACKGROUND: About 8% of U.S women are prescribed antidepressant medications around the time of pregnancy. Decisions about medication use in pregnancy can be swayed by the opinion of family, friends and online media, sometimes beyond the advice offered by healthcare providers. Exploration of the online social network response to research on antidepressant use in pregnancy could provide insight about how to optimize decision-making in this complex area. METHODS: For all 17 research articles published on the safety of antidepressant use in pregnancy in 2012, we sought to explore online social network activity regarding antidepressant use in pregnancy, via Twitter, in the 48h after a study was published, compared to the social network activity in the same period 1week prior to each article's publication...
March 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29455045/impact-of-transvaginal-modified-sacrospinous-ligament-fixation-with-mesh-for-the-treatment-of-pelvic-organ-prolapse-before-and-after-studies
#19
Qinyi Zhu, Huimin Shu, Guiqiang Du, Zhiyuan Dai
BACKGROUND: Pelvic organ prolapse (POP) is a common disease in women. The aim of this research was to evaluate the safety, efficacy and complication of transvaginal modified sacrospinous ligament fixation with mesh using for the treatment of vaginal vault prolapse. MATERIALS AND METHODS: This was a prospective study including information from 60 symptomatic women with anterior-apical pelvic floor prolapse. The patients underwent transvaginal modified sacrospinous ligament fixation combined with anterior vaginal wall mesh between May 2014 and Sep 2015...
February 15, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29454795/advances-in-crc-prevention-screening-and-surveillance
#20
Evelien Dekker, Douglas K Rex
Colorectal cancer (CRC) is amongst the most commonly diagnosed cancers and causes of death from cancer across the world. CRC can, however, be detected in asymptomatic patients at a curable stage, and several studies have shown lower mortality among patients who undergo screening compared to those who do not. Using colonoscopy in CRC screening also results in the detection of precancerous polyps that can be directly removed during the procedure, thereby reducing the incidence of cancer. In the past decade, convincing evidence has appeared that the effectiveness of colonoscopy as CRC prevention tool is associated with the quality of the procedure...
February 15, 2018: Gastroenterology
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