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https://www.readbyqxmd.com/read/27916594/application-of-abbreviated-protocol-of-magnetic-resonance-imaging-for-breast-cancer-screening-in-dense-breast-tissue
#1
Shuang-Qing Chen, Min Huang, Yu-Ying Shen, Chen-Lu Liu, Chuan-Xiao Xu
RATIONALE AND OBJECTIVES: The study aimed to evaluate the usefulness of an abbreviated protocol (AP) of magnetic resonance imaging (MRI) in comparison to a full diagnostic protocol (FDP) of MRI in the breast cancer screening with dense breast tissue. MATERIALS AND METHODS: There are 478 female participants with dense breast tissue and negative mammography results, who were imaged with MRI using AP and FDP. The AP and FDP images were analyzed separately, and the sensitivity and specificity of breast cancer detection were calculated...
December 1, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27916104/-preparation-and-application-of-monoclonal-antibodies-against-dr-region-of-na-k-atpase-%C3%AE-1-subunit
#2
Xiaofei Yan, Litao Wu, Xiaojuan DU, Jing Li, Fujun Zhang, Yan Han, Shemin Lyu, Dongmin Li
Objective To prepare monoclonal antibodies against DR region (897DVEDSYGQQWTYEQR911) of Na(+)-K(+)-ATPase α1 subunit and identify their properties. Methods BALB/c mice were immunized with DR-keyholelimpet hemocyanin (KLH). Splenocytes from the immunized mice were collected and subsequently fused with SP2/0 mouse myeloma cells. Positive hybridoma clones were obtained after cell fusion and selection. ELISA was used to detect DR antibody titer in the cell supernatants. DR region-specific monoclonal antibodies were analyzed by dot blotting, Western blotting and immunofluorescence assay...
December 2016: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/27880023/effect-of-cyclic-fatigue-tests-on-aging-and-their-translational-implications-for-survival-of-all-ceramic-tooth-borne-single-crowns-and-fixed-dental-prostheses
#3
REVIEW
Mutlu Özcan, Moritz Jonasch
PURPOSE: The objective of this systematic review was to elaborate the aging effect of cyclic fatigue tests on mechanical durability of all-ceramic single crowns and fixed dental prostheses (FDP). MATERIALS AND METHODS: Original scientific papers published in the MEDLINE (PubMed) database in English between 01/01/1950 and 12/31/2013 on cyclic loading on all-ceramics were included in this systematic review. The following MeSH terms, search terms, and their combinations were used: "in vitro," "stress mechanical," "crowns," "denture, partial, fixed," "dentistry," "fatigue," "all-ceramic," "zirconia," "fixed dental prosthesis," "FDP," "bridges," and "cyclic loading...
November 23, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27869629/coagulation-profile-of-patients-with-adolescent-idiopathic-scoliosis-undergoing-posterior-spinal-fusion
#4
Patrick Bosch, Tanya S Kenkre, Joanne A Londino, Antonio Cassara, Charles Yang, Jonathan H Waters
BACKGROUND: Blood loss and transfusion requirements during posterior spinal fusion for adolescent idiopathic scoliosis remain a concern. The mechanism of bleeding in these patients is poorly characterized. Thromboelastography is a comprehensive test of a patient's coagulation system commonly used in cardiac surgical procedures. It has not been well studied for use in patients with adolescent idiopathic scoliosis. METHODS: A prospective, observational study of the coagulation profile of patients with adolescent idiopathic scoliosis undergoing posterior spinal fusion is presented...
October 19, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27859471/volumetric-changes-at-pontic-sites-with-or-without-soft-tissue-grafting-a-controlled-clinical-study-with-a-10-year-follow-up
#5
Stefan P Bienz, Irena Sailer, Ignacio Sanz-Martin, Ronald E Jung, Christoph H F Hämmerle, Daniel S Thoma
OBJECTIVE: to evaluate volumetric changes of soft tissues at pontic sites in patients treated with or without soft tissue grafting over an observation period of 10 years. MATERIALS AND METHODS: A total of 17 patients receiving a tooth-borne fixed dental prosthesis (FDP) were enrolled in this study. Nine patients received a subepithelial connective tissue graft at the pontic site (test). Eight patients continued without soft tissue grafting (control). Baseline impressions were taken after delivery of the final FDP and at 10 years...
November 17, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27853760/enzymatic-synthesis-of-natural-aristolochene-from-a-non-natural-substrate
#6
Juan A Faraldos, Daniel J Grundy, Oscar Cascon, Stefano Leoni, Marc W van der Kamp, Rudolf K Allemann
The sesquiterpene cyclase aristolochene synthase from Penicillium roquefortii (PR-AS) has evolved to catalyse with high specificity (92%) the conversion of farnesyl diphosphate (FDP) to the bicyclic hydrocarbon (+)-aristolochene, the natural precursor of several fungal toxins. Here we report that PR-AS converts the unnatural FDP isomer 7-methylene farnesyl diphosphate to (+)-aristolochene via the intermediate 7-methylene germacrene A. Within the confined space of the enzyme's active site, PR-AS stabilises the reactive conformers of germacrene A and 7-methylene germacrene A, respectively, which are protonated by the same active site acid (most likely HOPPi) to yield the shared natural bicyclic intermediate eudesmane cation, from which (+)-aristolochene is then generated...
November 17, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27849977/337-fdp-level-at-hospital-admission-predicts-neurologic-outcomes-in-out-of-hospital-cardiac-arrest
#7
Yu-Ichi Ono, Tomonao Yoshida, Mineji Hayakawa, Kunihiko Maekawa, Hiromoto Murakami, Kenichi Katabami, Atsushi Sawamura, Satoshi Gando
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27830875/oblique-cord-chorda-obliqua-of-the-forearm-and-muscle-associated-fibrous-tissues-at-and-around-the-elbow-joint-a-study-of-human-fetal-specimens
#8
Zhe Wu Jin, Yu Jin, Masahito Yamamoto, Hiroshi Abe, Gen Murakami, Ting Feng Yan
In adults, the oblique cord or chorda obliqua separates the origins of the flexor pollicis longus (FPL) and flexor digitorum profundus (FDP) muscles from the supinator muscle and elbow joint. This study examined the topographic anatomy of the oblique cord and related muscles in fetuses. Semiserial sections of five mid-term fetuses of gestational age (GA) 14-16 weeks and 12 late-stage fetuses of GA 28-30 weeks were histologically examined and three forearms at GA 30 weeks were macroscopically evaluated. Late-stage fetuses showed a fascial structure between the supinator and FDP muscles...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27816011/sleep-alertness-and-alertness-management-among-commercial-airline-pilots-on-short-haul-and-long-haul-flights
#9
Mikael Sallinen, Maria Sihvola, Sampsa Puttonen, Kimmo Ketola, Antti Tuori, Mikko Härmä, Göran Kecklund, Torbjörn Åkerstedt
Airline pilots' sleep and on-duty alertness are important focus areas in commercial aviation. Until now, studies pertaining to this topic have mainly focused on specific characteristics of flights and thus a comprehensive picture of the matter is not well established. In addition, research knowledge of what airline pilots actually do to maintain their alertness while being on duty is scarce. To address these gaps in research knowledge, we conducted a field study on a representative sample of the airline pilots of a medium-sized airline...
November 2, 2016: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27795525/how-to-choose-and-understand-clinical-laboratory-tests-in-daily-clinical-management-of-hematologic-diseases
#10
Yoshinobu Seki
General statements have been published regarding the clinical laboratory tests for thrombosis and hemostasis to be used by hematologists who do not specialize in this field. Screening tests for bleeding are bleeding time, capillary fragility test, platelet count, prothrombin time, activated partial thromboplastin time (APTT), fibrinogen, fibrin/fibrinogen degradation products (FDP), and the cross mixing test conducted by measuring APTT. Screening tests for thrombosis and related factors include measurements of FDP, D-dimer, and thrombin-antithrombin complex...
2016: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/27784429/-clinical-features-of-liver-cirrhosis-complicated-by-portal-vein-thrombosis-and-related-risk-factors
#11
G S Lin, Q Xu, S Y Zhao, Y X Zhang
Objective: To investigate the clinical features of patients with liver cirrhosis complicated by portal vein thrombosis (PVT) and related risk factors. Methods: A total of 65 patients with liver cirrhosis complicated by PVT who were diagnosed and treated from June 2013 to June 2015 were enrolled as PVT group, and 70 cirrhotic patients without PVT were enrolled as controls (non-PVT group). The data collected included general information, results of laboratory examination, imaging findings, clinical manifestations, and complications...
July 20, 2016: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/27782170/a-reduction-based-sensor-for-acrolein-conjugates-with-the-inexpensive-nitrobenzene-as-an-alternative-to-monoclonal-antibody
#12
Masayuki Takamatsu, Koichi Fukase, Ritsuko Oka, Shinobu Kitazume, Naoyuki Taniguchi, Katsunori Tanaka
Acrolein, a highly toxic α, β-unsaturated aldehyde, has been a longstanding key biomarker associated with a range of disorders related to oxidative stresses. One of the most promising methods for detecting acrolein involves the use of antibodies that can recognize the acrolein-lysine conjugate, 3-formyl-3, 4-dehydropiperidines (FDP), within oxidatively stressed cells and tissues from various disease states. We have uncovered here that FDP could reduce nitroarenes in high yields at 100 °C in the presence of excess CaCl2 as a Lewis acid promoter...
October 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27751691/histopathology-of-brown-bullhead-ameiurus-nebulosus-smallmouth-bass-micropterus-dolomieu-and-yellow-perch-perca-flavescens-in-relation-to-polychlorinated-biphenyl-pcb-contamination-in-the-hudson-river
#13
Alfred E Pinkney, Mark S Myers, Michael A Rutter
From the 1940s through 1977, at least 590,000kg of polychlorinated biphenyls (PCBs) were released into the Hudson River from General Electric manufacturing plants located in Hudson Falls and Fort Edward, New York. In 1984, the U.S. Environmental Protection Agency designated a nearly 322km reach as the Hudson River PCBs Superfund Site. Here we describe a Fish Health Assessment study, part of a Natural Resource Damage Assessment, that evaluated the prevalence of toxicopathic lesions in adult brown bullhead (Ameiurus nebulosus), smallmouth bass (Micropterus dolomieu), and yellow perch (Perca flavescens)...
October 14, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27743213/four-years-survival-and-marginal-bone-loss-of-implants-in-patients-with-down-syndrome-and-cerebral-palsy
#14
José Ramón Corcuera-Flores, Julián López-Giménez, Julián López-Jiménez, Ana López-Giménez, Javier Silvestre-Rangil, Guillermo Machuca-Portillo
OBJECTIVES: To evaluate implant survival rate and marginal bone loss (MBL) after 4 years in patients with Down syndrome and cerebral palsy, compared with a healthy control group. MATERIAL AND METHODS: The case group comprises 102 implants in 19 patients (71 cerebral palsy, 21 Down syndrome), and the control group comprises 70 implants in 22 healthy patients. One implant per patient was selected (n = 41 implants) to take clustering effects into account. MBL was measured using two panoramic radiographs (after surgery and 4 years later)...
October 14, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27725182/structure-of-escherichia-coli-flavodiiron-nitric-oxide-reductase
#15
Célia V Romão, João B Vicente, Patrícia T Borges, Bruno L Victor, Pedro Lamosa, Elísio Silva, Luís Pereira, Tiago M Bandeiras, Cláudio M Soares, Maria A Carrondo, David Turner, Miguel Teixeira, Carlos Frazão
Flavodiiron proteins (FDPs) are present in organisms from all domains of life and have been described so far to be involved in the detoxification of oxygen or nitric oxide (NO), acting as O2 and/or NO reductases. The Escherichia coli FDP, named flavorubredoxin (FlRd), is the most extensively studied FDP. Biochemical and in vivo studies revealed that FlRd is involved in NO detoxification as part of the bacterial defense mechanisms against reactive nitrogen species. E. coli FlRd has a clear preference for NO as a substrate in vitro, exhibiting a very low reactivity toward O2...
October 7, 2016: Journal of Molecular Biology
https://www.readbyqxmd.com/read/27679870/assessment-of-forearm-muscle-spasticity-with-sonoelastography-in-patients-with-stroke
#16
Evren Yaşar, Emre Adigüzel, Serdar Kesikburun, Itır Yenihayat, Bilge Yılmaz, Rıdvan Alaca, Arif Kenan Tan
OBJECTIVES: Here we aimed to investigate the feasibility of sonoelastography to show muscle stiffness in post-stroke spasticity, and the relationship between sonoelastography findings and clinical spasticity scores in the spastic forearm muscles. METHODS: This study was carried out in a university rehabilitation center. 26 stroke patients with forearm muscle spasticity (≥ 1+ using the Modified Ashworth Scale score and ≥1 using the Tardieu scale) were included...
September 28, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27666497/marginal-fit-and-photoelastic-stress-analysis-of-cad-cam-and-overcast-3-unit-implant-supported-frameworks
#17
Anna Gabriella Camacho Presotto, Cláudia Lopes Brilhante Bhering, Marcelo Ferraz Mesquita, Valentim Adelino Ricardo Barão
STATEMENT OF PROBLEM: Several studies have shown the superiority of computer-assisted design and computer-assisted manufacturing (CAD-CAM) technology compared with conventional casting. However, an advanced technology exists for casting procedures (the overcasting technique), which may serve as an acceptable and affordable alternative to CAD-CAM technology for fabricating 3-unit implant-supported fixed dental prostheses (FDPs). PURPOSE: The purpose of this in vitro study was to evaluate, using quantitative photoelastic analysis, the effect of the prosthetic framework fabrication method (CAD-CAM and overcasting) on the marginal fit and stress transmitted to implants...
September 22, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27649162/acquisition-of-flavescence-dor%C3%A3-e-phytoplasma-by-scaphoideus-titanus-ball-from-different-grapevine-varieties
#18
Luciana Galetto, Dimitrios E Miliordos, Mattia Pegoraro, Dario Sacco, Flavio Veratti, Cristina Marzachì, Domenico Bosco
Flavescence dorée (FD) is a threat for wine production in the vineyard landscape of Piemonte, Langhe-Roero and Monferrato, Italy. Spread of the disease is dependent on complex interactions between insect, plant and phytoplasma. In the Piemonte region, wine production is based on local cultivars. The role of six local grapevine varieties as a source of inoculum for the vector Scaphoideus titanus was investigated. FD phytoplasma (FDP) load was compared among red and white varieties with different susceptibility to FD...
2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27648338/skeletal-muscle-metastases-to-the-flexor-digitorum-superficialis-and-profundus-from-urothelial-cell-carcinoma-and-review-of-the-literature
#19
Marco Guidi, Cesare Fusetti, Stefano Lucchina
Urothelial cell carcinoma (UCC) metastases to skeletal muscle are extremely rare and usually found in patients with advanced stage cancer. The most common sites of bladder cancer metastases are lymph nodes, lung, liver, and bones. Muscle is an unusual site of metastases from a distant primary cancer, due to several protective factors. We present a rare case of 76-year-old patient with metastases in the flexor digitorum superficialis (FDS) and flexor digitorum profundus (FDP) muscles, 2 years after a radical cystectomy for invasive UCC of the bladder...
2016: Case Reports in Urology
https://www.readbyqxmd.com/read/27639008/diagnostic-biomarkers-in-venous-thromboembolic-disease
#20
REVIEW
Benjamin Jacobs, Andrea Obi, Thomas Wakefield
OBJECTIVE: Venous thromboembolism (VTE) is a common disease with serious, often fatal sequelae. The optimal strategy for diagnosis of VTE remains unclear, although considerable progress has been made in this area. Several new biomarkers have showed promise for diagnosis of VTE, and more are under active investigation. We reviewed the literature for studies evaluating these diagnostic biomarkers. METHODS: We reviewed the English literature between 1990 and 2015, searching for papers evaluating diagnostic performance of biomarkers in VTE...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
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