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https://www.readbyqxmd.com/read/29322299/serum-parathyroid-hormone-and-25-hydroxyvitamin-d-concentrations-before-and-after-biliopancreatic-diversion
#1
Vanessa Tardio, Jean-Philippe Blais, Anne-Sophie Julien, Pierre Douville, Stefane Lebel, Laurent Biertho, Simon Marceau, Frédéric-Simon Hould, Claudia Gagnon
BACKGROUND: Biliopancreatic diversion with duodenal switch (BPD-DS) decreases vitamin D and calcium absorption, which may result in secondary hyperparathyroidism. This study aimed at evaluating the prevalence of vitamin D deficiency and secondary hyperparathyroidism before and after BPD-DS. METHODS: A retrospective analysis of patients who had undergone BPD-DS at a tertiary bariatric center between 2003 and 2010 and for whom simultaneous measurements of serum 25-hydroxyvitamin D and parathyroid hormone were available within 5 years post-op was performed...
January 10, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29322026/the-pgris-and-parathyroid-splinting-concepts-for-the-analysis-and-prognosis-of-protracted-hypoparathyroidism
#2
Antonio Sitges-Serra
Most patients with hypocalcemia after total thyroidectomy will recover the parathyroid function in a few weeks, but some 20-30% of them will still be in the need for replacement therapy one month after surgery and about 5-10% of those will develop permanent hypoparathyroidism. Although postoperative hypocalcemia has been related to several demographic and metabolic causes, parathyroid hormone (PTH) decline, resulting from autotransplantation, inadvertent excision or devascularization of the parathyroid glands, is the common final pathway...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29322021/the-role-and-timing-of-parathyroid-hormone-determination-after-total-thyroidectomy
#3
REVIEW
Ioanna G Mazotas, Tracy S Wang
Postoperative hypocalcemia is a common complication of total thyroidectomy resulting from manipulation, resection, or devascularization of the parathyroid glands. Parathyroid hormone (PTH) levels assessed in the perioperative period have been used to predict development of hypocalcemia. Articles examining the role of PTH measurement in the perioperative period following total or completion thyroidectomy are reviewed. Focus is placed on the timing of PTH measurement and the ability to predict which patients will develop hypocalcemia requiring supplementation...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29322018/a-nomogram-to-predict-the-likelihood-of-permanent-hypoparathyroidism-after-total-thyroidectomy-based-on-delayed-serum-calcium-and-ipth-measurements
#4
Antonio Sitges-Serra, Joaquín Gómez, Marcin Barczynski, Leyre Lorente-Poch, Maurizio Iacobone, Juan Sancho
Background: Retrospective studies have shown that delayed high-normal serum calcium and detectable iPTH are independent variables positively influencing outcome of prolonged parathyroid failure after total thyroidectomy (TT). The aim of the present study was to examine prospectively the ability of these two variables to predict permanent hypoparathyroidism in patients under replacement therapy for postoperative hypocalcemia. Methods: Prospective observational multicenter study of patients undergoing TT followed by postoperative parathyroid failure (serum calcium <8 mg/dL within 24 h and PTH <15 pg/mL 4 h after surgery)...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29310404/extracorporeal-membrane-oxygenation-combined-with-continuous-renal-replacement-therapy-in-cutaneous-burn-and-inhalation-injury-caused-by-hydrofluoric-acid-and-nitric-acid
#5
Qinhua Pu, Jinxian Qian, Weiyi Tao, Aixiang Yang, Jian Wu, Yaodong Wang
RATIONALE: Hydrofluoric acid (HF) is a highly corrosive agent and can cause corrosive burns. HF can penetrate deeply into tissues through intact skin and the lipid barrier, leading to painful liquefactive necrosis, and inducing hypocalcemia and hypomagnesemia. In this study, we hypothesize that continuous renal replacement therapy (CRRT) may be beneficial in addressing hemodynamic instability in cases of HF poisoning. PATIENT CONCERNS: A 25-year-old man fell into an electroplating pool containing 10% HF and 50% nitric acid...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29302725/does-surgery-without-lugol-s-solution-pretreatment-for-graves-disease-increase-surgical-morbidity
#6
Frederic Mercier, Mathieu Bonnal, Florian Fanget, Laure Maillard, Nathalie Laplace, Jean-Louis Peix, Jean-Christophe Lifante
BACKGROUND: Total thyroidectomy can be performed for Graves' disease after a euthyroid state is achieved using inhibitors of thyroid hormone synthesis (thioamides). However, hypervascularization of the thyroid gland is associated with increased hemorrhage risk, in addition to complicating identification of the recurrent laryngeal nerve and parathyroid gland. Saturated iodine solution (Lugol's solution) has been recommended to reduce thyroid gland hypervascularization and intraoperative blood loss, although this approach is not used at our center based on our experience that it induces thyroid firmness and potentially hypoparathyroidism...
January 4, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29302480/comparison-of-indocyanine-green-fluorescence-and-parathyroid-autofluorescence-imaging-in-the-identification-of-parathyroid-glands-during-thyroidectomy
#7
Bora Kahramangil, Eren Berber
Background: Indocyanine green fluorescence (ICGF) and parathyroid autofluorescence (AF) are two new techniques that aid in the identification of parathyroid glands (PG) intraoperatively during thyroidectomy. There is no study comparing the efficacy of these techniques. Methods: This was an IRB-approved clinical study comparing the utility of ICGF and AF for identification of PGs during thyroidectomy. Data were collected prospectively. Both techniques were compared to naked eye (NE) for PG detection...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29290070/one-hour-postoperative-parathyroid-hormone-levels-do-not-reliably-predict-hypocalcemia-after-thyroidectomy
#8
Zeyad Sahli, Alireza Najafian, Stacie Kahan, Eric B Schneider, Martha A Zeiger, Aarti Mathur
INTRODUCTION: Hypocalcemia is a well-known complication after total thyroidectomy. Studies have indicated that the presence of low postoperative parathyroid hormone (PTH) levels can predict hypocalcemia. However, definitive study designs are lacking. The aim of this study was to determine whether postoperative PTH alone can accurately predict postoperative biochemical hypocalcemia. METHODS: Under IRB approval, a prospective study of 218 consecutive patients who underwent total or completion thyroidectomy by two surgeons between June 2014 and June 2016 was performed...
December 31, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29285391/f18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-bone-hemangiopericytoma
#9
Yiyan Liu
Bone hemangiopericytoma (HPC) is extremely rare, and its clinical manifestations and radiographic features are nonspecific. There are few case reports about application of F18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in HPC. A total of four subjects with pathologically diagnosed bone HPC had FDG PET/CT for staging and/or restaging bone HPC. Medical records were retrospectively reviewed for radiological, pathological and follow-up information. All primary bone and metastatic lesions demonstrated high FDG avidity on PET/CT, which also revealed the adjacent soft tissue involvement and synchronous lesion...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29280194/effect-of-prophylactic-calcitriol-administration-on-serum-ionized-calcium-concentrations-after-parathyroidectomy-78-cases-2005-2015
#10
A J Armstrong, J G Hauptman, B J Stanley, E Klocke, M Burneko, D E Holt, J J Runge, J A Rubin
BACKGROUND: Prophylactic administration of calcitriol has been suggested to mitigate the risk of hypocalcemia after parathyroidectomy. The effect of calcitriol on postoperative serum ionized calcium concentrations has not been evaluated in dogs after parathyroidectomy. HYPOTHESIS/OBJECTIVES: To determine the effect of prophylactic calcitriol administration on postoperative serum ionized calcium (iCa) concentrations in dogs with primary hyperthyroidism (PHPTH) treated by parathyroidectomy...
December 27, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29279189/hypoparathyroidism-what-is-the-best-calcium-carbonate-supplementation-intake-form
#11
Loraine Gollino, Maria Fernanda Giovanetti Biagioni, Nathalia Regina Sabatini, José Vicente Tagliarini, José Eduardo Corrente, Sérgio Alberto Rupp de Paiva, Gláucia Maria Ferreira da Silva Mazeto
INTRODUCTION: In hypoparathyroidism, calcium supplementation using calcium carbonate is necessary for the hypocalcemia control. The best calcium carbonate intake form is unknown, be it associated with feeding, juice or in fasting. OBJECTIVE: The objective was to evaluate the calcium, phosphorus and Calcium×Phosphorus product serum levels of hypoparathyroidism women after total thyroidectomy, following calcium carbonate intake in three different forms. METHODS: A crossover study was carried out with patients presenting definitive hypoparathyroidism, assessed in different situations (fasting, with water, orange juice, breakfast with a one-week washout)...
November 15, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29274983/effects-of-prepartum-dietary-cation-anion-difference-and-source-of-vitamin-d-in-dairy-cows-health-and-reproductive-responses
#12
N Martinez, R M Rodney, E Block, L L Hernandez, C D Nelson, I J Lean, J E P Santos
The objectives of the experiment were to evaluate the effects of feeding diets with distinct dietary cation-anion difference (DCAD) levels and supplemented with 2 sources of vitamin D during the prepartum transition period on postpartum health and reproduction in dairy cows. The hypotheses were that feeding acidogenic diets prepartum would reduce the risk of hypocalcemia and other diseases, and the benefits of a negative DCAD treatment on health would be potentiated by supplementing calcidiol compared with cholecalciferol...
December 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29248221/method-comparison-and-validation-of-a-prototype-device-for-measurement-of-ionized-calcium-concentrations-cow-side-against-a-point-of-care-instrument-and-a-benchtop-blood-gas-analyzer-reference-method
#13
R C Neves, T Stokol, K D Bach, J A A McArt
The objective of this study was to assess an optimized ion-selective electrode Ca-module prototype as a potential cow-side device for ionized Ca (iCa) measurements in bovine blood. A linearity experiment showed no deviation from linearity over a range of iCa concentrations compared with a commercial point-of-care (POC) device commonly used in the field (POCVS; VetScan i-STAT, Abaxis North America, Union City, CA) and a laboratory gold standard benchtop blood-gas analyzer [reference analyzer (RA); ABL-800 FLEX, Radiometer Medical, Copenhagen, Denmark]...
December 13, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29247429/prevalence-of-hypocalcemia-in-seizures-in-infancy
#14
Mahesh Kamate, Kanika Sharma, Vishwanath Patil
A one-year prospective study on developmentally normal children between 1-mo to 2-y with seizures was done to study the prevalence of hypocalcemia. The contribution of hypovitaminosis-D to hypocalcemia was also studied. Of 78 infants (51 boys) enrolled, 18 (23.1%) had hypocalcemia. Fifteen (19.2%) had hypocalcemia secondary to hypovitaminosis-D and 3 (3.8%) had hypomagnesemia. In infants aged less than 6 mo who were exclusively breastfed, 15 (41.67%) had hypocalcemia in comparison to other two age groups [2 (10...
December 16, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29238849/video-assisted-thyroidectomy-for-papillary-thyroid-carcinoma-oncologic-outcome-in-patients-with-follow-up%C3%A2-%C3%A2-%C3%A2-10-years
#15
Rocco Bellantone, Marco Raffaelli, Carmela De Crea, Luca Sessa, Emanuela Traini, Pietro Princi, Celestino Pio Lombardi
BACKGROUND: Video-assisted thyroidectomy (VAT) arisen as a valid treatment for selected patients with papillary thyroid carcinoma (PTC), but no data concerning long-term oncologic outcome are available. The primary aim of the study was to evaluate the oncologic outcome of patients who underwent VAT for PTC with a follow-up ≥ 10 years. METHODS: The medical charts of all the patients who successfully underwent VAT for PTC were reviewed. The patients with a minimum follow-up period of 120-months were included...
December 13, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29238762/etelcalcetide-injectable-calcimimetic-for-the-treatment-of-secondary-hyperparathyroidism-in-hemodialysis-dependent-patients
#16
P A Ureña Torres, J Bover, M Cohen-Solal
Chronic kidney disease is associated with mineral and bone disorders that are now considered as a syndrome. One of the major complications of this syndrome is secondary hyperparathyroidism (SHPT). SHPT increases bone turnover and the risk of fracture. SHPT is also associated with cardiovascular calcification and high mortality risk. The classical medical therapies of SHPT lack long-term efficacy and have undesirable effects on serum calcium and phosphate levels. Surgical parathyroidectomy is a radical therapeutic solution potentially exposing patients to a permanent state of hypoparathyroidism among other complications...
September 2017: Drugs of Today
https://www.readbyqxmd.com/read/29238129/persistent-hypocalcemia-and-hungry-bone-syndrome-after-parathyroidectomy-and-renal-transplantation-in-a-patient-with-end-stage-renal-disease
#17
Hamid Tayyebi-Khosroshahi, Farahnoush Farnood, Maryam Ghorbanian, Farid Karkon-Shayan, Mohammad Naghavi-Behzad
Hungry bone syndrome (HBS) defines as persistent and severe hypocalcemia after parathyroidectomy surgery. It is treated by oral or venous discrimination of calcium carbonate. The present treatment is mostly effective. Hereby, we describe a 60-year-old man who had developed hyperparathyroidism secondary to end-stage renal disease and then parathyroidectomy was performed for him twice before renal transplantation. Up to 500 vials of calcium gluconate (100 mg/ml calcium gluconate 10%) were administered for him to control serum calcium level after parathyroidectomy and renal transplantation...
January 2017: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/29230244/tumor-lysis-syndrome-in-patients-with-hematological-malignancies
#18
REVIEW
Yohannes Belay, Ketsela Yirdaw, Bamlaku Enawgaw
Tumor lysis syndrome is a metabolic complication that may follow the initiation of cancer therapy. It commonly occurs in hematological malignant patients particularly non-Hodgkin's lymphoma and acute leukemia due to chemotherapy or spontaneously. It is characterized by a biochemical abnormality such as hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia and its clinical outcome is directly related to these biochemical abnormalities. Prevention and treatment of tumor lysis syndrome depend on immediate recognition of patients at risk...
2017: Journal of Oncology
https://www.readbyqxmd.com/read/29227270/-clinical-characteristics-of-congenital-heart-diseases-associated-with-connective-tissue-displasia-at-children-living-in-east-region-of-kazakhstan
#19
M Madiyeva, T Rymbayeva
The frequency of the combination of congenital heart defects (CHD) and connective tissue dysplasia remains poorly understood. And connective tissue dysplasia enhance severity the clinical of CHD. The aim of the study was to conduct a clinical and laboratory analysis of combinations of congenital heart defects and connective tissue dysplasia in children of Semey and to determine the risk for the development of these pathologies. The object of the study is the children of Semey (East Kazakhstan) aged 1-14 with congenital heart defects (CHD), with connective tissue dysplasia, healthy children and their mothers...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29225880/tumor-lysis-syndrome-with-massive-hyperphosphatemia-and-hyperuricemia
#20
Abhilash Koratala
Tumor lysis syndrome (TLS) occurs when tumor cells release their contents into the bloodstream, typically in response to chemotherapy, leading to the characteristic findings of hyperuricemia, hyperkalemia, hyperphosphatemia, hypocalcemia, and acute kidney injury. Twinkle artifacts on renal ultrasound may indicate calcium phosphate deposits in such patients.
December 2017: Clinical Case Reports
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