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https://www.readbyqxmd.com/read/28531205/cost-analysis-of-human-papillomavirus-related-cervical-diseases-and-genital-warts-in-swaziland
#1
Themba G Ginindza, Benn Sartorius, Xolisile Dlamini, Ellinor Östensson
BACKGROUND: Human papillomavirus (HPV) has proven to be the cause of several severe clinical conditions on the cervix, vulva, vagina, anus, oropharynx and penis. Several studies have assessed the costs of cervical lesions, cervical cancer (CC), and genital warts. However, few have been done in Africa and none in Swaziland. Cost analysis is critical in providing useful information for economic evaluations to guide policymakers concerned with the allocation of resources in order to reduce the disease burden...
2017: PloS One
https://www.readbyqxmd.com/read/28528906/warts-signaling-controls-organ-and-body-growth-through-regulation-of-ecdysone
#2
Morten E Moeller, Stanislav Nagy, Stephan U Gerlach, Karen C Soegaard, E Thomas Danielsen, Michael J Texada, Kim F Rewitz
Coordination of growth between individual organs and the whole body is essential during development to produce adults with appropriate size and proportions [1, 2]. How local organ-intrinsic signals and nutrient-dependent systemic factors are integrated to generate correctly proportioned organisms under different environmental conditions is poorly understood. In Drosophila, Hippo/Warts signaling functions intrinsically to regulate tissue growth and organ size [3, 4], whereas systemic growth is controlled via antagonistic interactions of the steroid hormone ecdysone and nutrient-dependent insulin/insulin-like growth factor (IGF) (insulin) signaling [2, 5]...
May 17, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28528686/hpv-entry-into-cells
#3
REVIEW
Pinar Aksoy, Elinor Y Gottschalk, Patricio I Meneses
Human papillomavirus (HPV) is a sexually transmitted virus responsible for the development of cervical cancer, anal cancer, head and throat cancers, as well as genital area warts. A major focus of current HPV research is on preventing the virus from entering a cell and transferring its genetic material to the nucleus, thus potentially preventing the development of cancer. Although the available HPV vaccines are extremely successful, approximately 15 additional cancer-causing HPVs have been identified that the vaccines do not protect against...
April 2017: Mutation Research
https://www.readbyqxmd.com/read/28528617/grotesque-face-secondary-to-immunotherapy-cure-circumvallating-to-curse
#4
Keshavamurthy Vinay, Tarun Narang, Sunil Dogra, Uma N Saikia
A 45-year-old woman presented with multiple, slightly painful, reddish, nodular facial lesions that had developed at the site of Mycobacterium w vaccine injections given for her facial warts 4 weeks prior. She had not received a sensitization dose of Mycobacterium w vaccine, and all of the inflamed lesions were injected at the same time. On examination, approximately 20 erythematous, succulent nodules of variable size were noted over the cheeks and forehead (Figure 1). Some of these lesions had purulent discharge due to secondary infection...
2017: Skinmed
https://www.readbyqxmd.com/read/28523836/a-case-series-of-verrucae-vulgares-mimicking-hyperkeratosis-in-individuals-with-diabetic-foot-ulcers
#5
D R Quast, M A Nauck, F G Bechara, J J Meier
BACKGROUND: Diabetic foot ulcers are a common complication in the advanced stages of diabetes mellitus. Certain lesions may be refractory to usual treatments with prolonged healing. In these cases, differential diagnoses to classical ulcers should be considered. Although plantar warts are a common and easy-to-diagnose finding in the general population, diagnosis can be challenging in people with diabetic foot ulcers, as they mimic hyperkeratosis in these people. CASE REPORT: We report seven cases of people with diabetic foot ulcers and verrucae vulgares mimicking treatment-refractory hyperkeratosis, presenting to our centre between 2014 and 2016...
May 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28515303/spontaneous-and-vaccine-induced-clearance-of-mus-musculus-papillomavirus-type-1-mmupv1-muspv1-infection
#6
Rosie T Jiang, Joshua W Wang, Shiwen Peng, Tsui-Chin Huang, Chenguang Wang, Fabiana Cannella, Yung-Nien Chang, Raphael P Viscidi, Simon R A Best, Chien-Fu Hung, Richard B S Roden
Mus musculus Papillomavirus1 (MmuPV1/MusPV1) induces persistent papillomas in immunodeficient mice but not common laboratory strains. To facilitate study of immune control, we sought an outbred and immune competent laboratory mouse strain in which persistent papillomas could be established. We found that challenge of SKH1 mice (Crl:SKH1-Hrhr) by scarification on their tail with MmuPV1 resulted in three clinical outcomes: 1) persistent (>2 months) papillomas (∼20%), 2) transient papillomas that spontaneously regress typically within 2 months (∼15%), 3) no visible papillomas and viral clearance (∼65%)...
May 17, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28512628/dysplasia-of-granulocytes-in-a-patient-with-hpv-disease-recurrent-infections-and-b-lymphopenia-a-novel-variant-of-whim-syndrome
#7
Giusella M F Moscato, Erica Giacobbi, Lucia Anemona, Silvia Di Cesare, Gigliola Di Matteo, Massimo Andreoni, Alessandro Mauriello, Viviana Moschese
WHIM syndrome is a condition in which affected persons have chronic peripheral neutropenia, lymphopenia, abnormal susceptibility to human papilloma virus infection, and myelokathexis. Myelokathexis refers to the retention of mature neutrophils in the bone marrow (BM), which accounts for degenerative changes and hypersegmentation. Most patients present heterozygous autosomal dominant mutations of the gene encoding CXCR4. Consequently, aberrant CXCL12/CXCR4 signaling impairs the receptor downregulation causing hyperactivation (gain-of-function) that affects BM homing for myelopoiesis and lymphopoiesis and the release of neutrophils in the bloodstream...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28499554/effectiveness-of-hpv-vaccines-against-genital-warts-in-women-from-valencia-spain
#8
Esther Navarro-Illana, Mónica López-Lacort, Pedro Navarro-Illana, Juan José Vilata, Javier Diez-Domingo
OBJECTIVES: To assess the effectiveness of the HPV vaccines in preventing genital warts in young women. DESIGN: Population-based study using health databases. SETTING: Valencian Community (Spain). PARTICIPANTS: All girls and women aged 14-19years who were registered in the Valencian Community between January 2009 and December 2014 (n=279,787). MAIN OUTCOME MEASURES: Incident cases of genital warts were defined as the first activation of diagnosis code ICD-9-CM 078...
June 5, 2017: Vaccine
https://www.readbyqxmd.com/read/28499288/impact-of-number-of-human-papillomavirus-vaccine-doses-on-genital-warts-diagnoses-among-a-national-cohort-of-u-s-adolescents
#9
Rebecca B Perkins, Mengyun Lin, Sherrie F Wallington, Amresh Hanchate
BACKGROUND: The impact of fewer than 3 doses of human papillomavirus (HPV) vaccine on genital warts is uncertain. METHODS: Using the Truven Health Analytics Marketscan administrative database, we compared rates of genital warts among women receiving 0, 1, 2, or 3 doses of HPV vaccine. Females aged 9 to 18 years on January 1, 2007, who were continuously enrolled in the database through December 31, 2013, were included. Patients were assigned an HPV dose state (0, 1, 2, or 3) based on the last recorded dose...
June 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28496303/development-of-a-potent-invigorator-of-immune-responses-endowed-with-both-preventive-and-therapeutic-properties
#10
REVIEW
Gursaran P Talwar, Jagdish C Gupta, Abu S Mustafa, Hemanta K Kar, Kiran Katoch, Shreemanta K Parida, Prabhakara P Reddi, Niyaz Ahmed, Vikram Saini, Somesh Gupta
This article reviews briefly the making of an immunoprophylactic-cum-immunotherapeutic vaccine against leprosy. The vaccine is based on cultivable, heat-killed atypical mycobacteria, whose gene sequence is now known. It has been named Mycobacterium indicus pranii. It has received the approval of the Drug Controller General of India and the US Food and Drug Administration. Besides leprosy, M. indicus pranii has found utility in the treatment of category II ("difficult to treat") tuberculosis. It also heals ugly anogenital warts...
2017: Biologics: Targets & Therapy
https://www.readbyqxmd.com/read/28495003/viral-warts-human-papilloma-virus-as-a-potential-risk-for-breast-cancer-among-younger-females
#11
Suleman Atique, Chung-Ho Hsieh, Ruei-Ting Hsiao, Usman Iqbal, Phung Anh Alex Nguyen, Md Mohaimenul Islam, Yu-Chuan Jack Li, Chien-Yeh Hsu, Ting-Wu Chuang, Shabbir Syed-Abdul
INTRODUCTION: There have been several reports on the role of human papillomavirus (HPV) in the etiology of breast cancer. To our knowledge, this is first study to use disease-disease association data-mining approach to analyzing viral warts and breast cancer to be conducted in Taiwanese population. MATERIALS AND METHODS: We analyzed the Taiwan's National Health Insurance database (NHIDM data comprising of 23 million patient data) to examine the association between viral warts and female breast carcinoma...
June 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28489473/treatment-of-recalcitrant-plantar-warts-with-long-pulsed-nd-yag-laser-versus-cantharidin-podophylline-resin-salicylic-acid
#12
Soheir Ghonemy
BACKGROUND: Treatment for recalcitrant plantar warts remains a continuing challenge as the options for treatment have differing levels of success. Long-Pulsed Nd: YAG Laser is considered a good treatment modality in resistant plantar warts. On the other hand high, cure rates have been reported with a topical proprietary formulation consisting of 1% cantharidin, 5% podophyllotoxin, 30% salicylic acid. AIM: To compare the efficacy of 1% cantharidin, 20% podophylline resin, 30% salicylic acid (CPS) versus Long-Pulsed Nd:YAG Laser in the treatment of recalcitrant plantar warts...
May 10, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28488451/giant-warts-of-the-hand-treated-surgically
#13
J Chateau, M Guillot, A Mojallal
No abstract text is available yet for this article.
March 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28485812/epidemiology-of-human-papillomavirus-on-anogenital-warts-in-portugal-the-hercoles-study
#14
J Azevedo, A Pista, C Lisboa, I Santo, L Azevedo, M J Cunhax
BACKGROUND: Anogenital warts (AGW) are one of the most prevalent sexually transmitted disease worldwide. Approximately 90% of AGWs are related to infection by HPV 6 and 11. However, AGW have been associated with infection by multiple genotypes, including HR-HPV, which may be associated with a long-term increased risk of anogenital cancer. OBJECTIVE: This observational prospective epidemiological study aims to estimate the type-specific HPV distribution on incident AGWs in both genders, and additionally to assess the frequency of anal and oral HPV infection in patients with AGWs...
May 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28484898/virus-induced-cancers-of-the-skin-and-mucosa-are-we-dealing-with-smoking-guns-or-smoke-and-mirrors-in-the-operating-theatre
#15
Peter K C Goon, Patrick K Y Goon, Eunice K H Tan, Robin A F Crawford, Nick J Levell, Holger Sudhoff
INTRODUCTION: Human papillomavirus (HPV) alone is thought to cause ~610,000 cases of cancer per year, and is the dominant aetiological agent for ano-genital (esp. cervical) and head and neck cancers (esp. oropharyngeal). Merkel cell polyomavirus (MCV) is a more recently discovered virus which causes Merkel cell carcinoma, a rare but highly aggressive skin malignancy. METHODS: We explored the available published evidence to see if transmission of live HPV or MCV virus in smoke generated by laser or diathermy was feasible, and would pose an infection risk...
May 8, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28484110/traditional-chinese-medicine-for-human-papillomavirus-hpv-infections-a-systematic-review
#16
Jing Lin, Lanting Chen, Xuemin Qiu, Na Zhang, Qiting Guo, Yan Wang, Mingyan Wang, Hans-Jürgen Gober, Dajin Li, Ling Wang
Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been a handful of treatments for HPV-associated benign or malignant diseases, traditional Chinese medicine being one of them. This systematic review focuses on the application of traditional Chinese medicine in HPV infection and related diseases on the basis of clinical findings...
May 6, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/28475390/small-cryotherapy-devices-for-the-treatment-of-skin-warts
#17
Viktor A Zouboulis, Christos C Zouboulis
STUDY PURPOSE: Effectiveness of cryotherapy on skin wart models. MATERIALS/METHODS: Two small cryotherapy devices, Wartner and Wortie, were administered for 10"-60" on tomatoes and potatoes used as skin wart models. Frozen surface and depth were evaluated by standardized photography and computer analysis. Tissue temperature at depths of 0.1-10 mm was assessed during treatment by an electronic thermometer. RESULTS: Cryotherapy induced a transient freezing of the tomato surface...
May 5, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28472571/optimising-cryosurgery-technique
#18
William C Cranwell, Rodney Sinclair
BACKGROUND: Cryosurgery is an effective, simple and inexpensive treatment used extensively in general practice and dermatology. It is used most commonly for actinic keratoses and warts; however, a large number of benign, premalignant and malignant skin diseases can also be treated. OBJECTIVE: The objective of this article is to help readers improve their cryosurgery technique. DISCUSSION: Application of the cryogenic agent (most commonly liquid nitrogen) to the skin induces rapid freezing followed by slow thawing...
2017: Australian Family Physician
https://www.readbyqxmd.com/read/28468737/tattoo-and-warts-efficacy-of-topical-immunotherapy
#19
Luca Fania, Donatella Sordi, Gianluca Pagnanelli, Andrea CavanI, Cinzia Mazzanti
No abstract text is available yet for this article.
May 3, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28466193/efficacy-of-nd-yag-laser-therapy-for-the-treatment-of-verrucae-a-literature-review
#20
Vincent M Hsu, Adam S Aldahan, John P Tsatalis, Marina Perper, Keyvan Nouri
Verrucae are benign epithelial proliferations, characteristically 1-20 mm in diameter, caused by human papilloma virus (HPV) infection occurring on the skin and mucosa (Photomed Laser Surg 33(6):338-42, 2015; Lasers Med Sci 29(3):1111-6, 2014). Prevalence of verrucae is 5-20% in children and young adults with peak incidence reported during teenage years (Lasers Med Sci 29(3):1111-6, 2014; J Am Acad Dermatol 22(4):547-66, 1990; J Korean Med Sci 24(5):889-93, 2009). Patients often express significant displeasure with quality of life due to this cosmetic insecurity, as well as functional problems and physical discomfort when they occur on palms of hands and soles of feet...
May 2, 2017: Lasers in Medical Science
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