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Jerker Rönnberg, Thomas Lunner, Elaine Hoi Ning Ng, Björn Lidestam, Adriana Agatha Zekveld, Patrik Sörqvist, Björn Lyxell, Ulf Träff, Wycliffe Yumba, Elisabet Classon, Mathias Hällgren, Birgitta Larsby, Carine Signoret, M Kathleen Pichora-Fuller, Mary Rudner, Henrik Danielsson, Stefan Stenfelt
OBJECTIVE: The aims of the current n200 study were to assess the structural relations between three classes of test variables (i.e. HEARING, COGNITION and aided speech-in-noise OUTCOMES) and to describe the theoretical implications of these relations for the Ease of Language Understanding (ELU) model. STUDY SAMPLE: Participants were 200 hard-of-hearing hearing-aid users, with a mean age of 60.8 years. Forty-three percent were females and the mean hearing threshold in the better ear was 37...
November 2016: International Journal of Audiology
Beatriz Caicedo, Dedsy Berbesi Fernández
OBJECTIVE: To evaluate the influence of income inequality and poverty in the towns of Bogotá, Colombia, on poor self-rated health among their residents. METHODS: The study was based on a multipurpose survey applied in Bogotá-Colombia. A hierarchical data structure (individuals=level1, locations=level 2) was used to define a logit-type multilevel logistic model. The dependent variable was self-perceived poor health, and local variables were income inequality and poverty...
March 2015: Gaceta Sanitaria
Seyfi Emir, Selim Sözen, Ilhan Bali, Sibel Özkan Gürdal, Bünyamin Cüneyt Turan, Oguzhan Yıldırım, Tarkan Yetişyiğit
OBJECTIVE: Gastric cancer is a worldwide aggressive tumor with a bad prognosis. The purpose of this study was to retrospectively investigate operative findings of 53 patients aged over 70 with gastric cancer who underwent laporoscopic operations in our clinic. MATERIAL AND METHODS: A retrospective review of all patients who underwent laporoscopic surgery for pathologically confirmed gastric cancer at our clinic between March 2008 and October 2010 was conducted. D1 resection (Level1 lymphadenectomy) was compared with D2 resection (Levels 1 and 2 lymphadenectomy)...
2014: International Journal of Clinical and Experimental Medicine
Jung-Min Lee, John L Hays, Christina M Annunziata, Anne M Noonan, Lori Minasian, Jo Anne Zujewski, Minshu Yu, Nicolas Gordon, Jiuping Ji, Tristan M Sissung, William D Figg, Nilofer Azad, Bradford J Wood, James Doroshow, Elise C Kohn
BACKGROUND: Olaparib has single-agent activity against breast/ovarian cancer (BrCa/OvCa) in germline BRCA1 or BRCA2 mutation carriers (gBRCAm). We hypothesized addition of olaparib to carboplatin can be administered safely and yield preliminary clinical activity. METHODS: Eligible patients had measurable or evaluable disease, gBRCAm, and good end-organ function. A 3 + 3 dose escalation tested daily oral capsule olaparib (100 or 200mg every 12 hours; dose level1 or 2) with carboplatin area under the curve (AUC) on day 8 (AUC3 day 8), then every 21 days...
June 2014: Journal of the National Cancer Institute
Edward K Rodriguez, Christina Boulton, Michael J Weaver, Lindsay M Herder, Jordan H Morgan, Aron T Chacko, Paul T Appleton, David Zurakowski, Mark S Vrahas
INTRODUCTION: Reported initial success rates after lateral locked plating (LLP) of distal femur fractures have led to more concerning outcomes with reported nonunion rates now ranging from 0 to 21%. Reported factors associated with nonunion include comorbidities such as obesity, age and diabetes. In this study, our goal was to identify patient comorbidities, injury and construct characteristics that are independent predictors of nonunion risk in LLP of distal femur fractures; and to develop a predictive algorithm of nonunion risk, irrespective of institutional criteria for clinical intervention variability...
March 2014: Injury
M Berraho, C Nejjari, K El Rhazi, J F Tessier, J F Dartigues, P Barberger-Gateau, C Raherison
OBJECTIVE: To determine the association between dyspnea at entry into the PAQUID cohort and 13-year mortality, taking into consideration BMI and other mortality-related factors. METHODS: HASH(0x3b97a20) DESIGN: Longitudinal study. SETTING: In Dordogne and Gironde, South Western France. SUBJECTS: A total of 3646 French community dwellers aged 65 years old and over from the PAQUID study were included...
2013: Journal of Nutrition, Health & Aging
Fabio R Serpiello, Michael J McKenna, Nigel K Stepto, David J Bishop, Robert J Aughey
We investigated the acute and chronic responses to multiple sets of repeated-sprint exercise (RSE), focusing on changes in acceleration, intermittent running capacity and physiological responses. Ten healthy young adults (7 males, 3 females) performed an incremental test, a Yo-Yo intermittent recovery test level1 (Yo-Yo IR1), and one session of RSE. RSE comprised three sets of 5 × 4-s maximal sprints on a non-motorised treadmill, with 20 s of passive recovery between repetitions and 4.5 min of passive recovery between sets...
April 2011: European Journal of Applied Physiology
Yoshihisa Morita, Ju Mizuno, Shinji Takada, Seki Yunokawa, Shigeho Morita
A 33-year-old pregnant woman, who had undergone three previous cesarean sections and suspected of having placenta accrete, was scheduled for artificial abortion and abdominal total hysterectomy at 15 weeks gestation because of a probable high mortality rate. The general anesthesia was induced using fentanyl, propofol, and vecuronium and maintained with sevoflurane, fentanyl, and vecuronium, in combination with epidural anesthesia using ropivacaine. During the operation, we found that the placenta had penetrated into the posterior abdominal peritoneum and bladder wall...
August 2009: Masui. the Japanese Journal of Anesthesiology
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