Yichi Xu, Haoye Meng, Heyong Yin, Zhen Sun, Jiang Peng, Xiaolong Xu, Quanyi Guo, Wenjing Xu, Xiaoming Yu, Zhiguo Yuan, Bo Xiao, Cheng Wang, Yu Wang, Shuyun Liu, Shibi Lu, Zhaoxu Wang, Aiyuan Wang
Degradation limits the application of magnesium alloys, and evaluation methods for non-traumatic in vivo quantification of implant degradation and bone formation are imperfect. In the present study, a micro-arc-oxidized AZ31 magnesium alloy was used to evaluate the degradation of implants and new bone formation in 60 male New Zealand white rabbits. Degradation was monitored by weighing the implants prior to and following implantation, and by performing micro-computed tomography (CT) scans and histological analysis after 1, 4, 12, 24, 36, and 48 weeks of implantation...
January 2018: Experimental and Therapeutic Medicine