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https://www.readbyqxmd.com/read/29752709/association-between-a-pro-plant-based-dietary-score-and-cancer-risk-in-the-prospective-nutrinet-sant%C3%A3-cohort
#1
Abou Kane-Diallo, Bernard Srour, Laury Sellem, Mélanie Deschasaux, Paule Latino-Martel, Serge Hercberg, Pilar Galan, Philippine Fassier, Françoise Guéraud, Fabrice H Pierre, Emmanuelle Kesse-Guyot, Benjamin Allès, Mathilde Touvier
Diverse plant products (e.g. fruits, vegetables, legumes) are associated with decreased cancer risk at several locations while red and processed meat were found to increase cancer risk. A pro plant-based dietary score reflecting the relative contribution of consumed plant vs animal products was developed, and was associated with lower overall mortality, type 2 diabetes and cardiovascular disease risk, among omnivorous adults. For the first time, we investigated the prospective associations between this pro plant-based dietary score and cancer risk...
May 11, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29744870/circadian-nutritional-behaviours-and-cancer-risk-new-insights-from-the-nutrinet-sant%C3%A3-prospective-cohort-study
#2
Bernard Srour, Sabine Plancoulaine, Valentina A Andreeva, Philippine Fassier, Chantal Julia, Pilar Galan, Serge Hercberg, Mélanie Deschasaux, Paule Latino-Martel, Mathilde Touvier
Circadian disruption has been classified as probably carcinogenic to humans by the World Health Organization's International Agency for Research on Cancer. The circadian clock is subject to environmental factors, particularly light exposure and food intake rhythms. However, the association between nutritional circadian behaviours and cancer is not well understood. We investigated the longitudinal associations between number of eating episodes, night-time fasting duration, time of first and last eating episodes, as well as nutritional quality of last eating episode, respectively, with breast and prostate cancer risks, the two main cancer locations in women and men respectively...
May 9, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29616321/saturated-mono-and-polyunsaturated-fatty-acid-intake-and-cancer-risk-results-from-the-french-prospective-cohort-nutrinet-sant%C3%A3
#3
Laury Sellem, Bernard Srour, Françoise Guéraud, Fabrice Pierre, Emmanuelle Kesse-Guyot, Thibault Fiolet, Céline Lavalette, Manon Egnell, Paule Latino-Martel, Philippine Fassier, Serge Hercberg, Pilar Galan, Mélanie Deschasaux, Mathilde Touvier
PURPOSE: Lipid intakes such as saturated (SFA), monounsaturated (MUFA) and polyunsaturated (PUFA) fatty acids have been widely studied regarding cardiovascular health, but their relevance to cancer is unclear. Inconsistent epidemiological results may be explained by varied mechanisms involving PUFAs and redox balance, inflammatory status and cell signalling, along with interactions with other dietary components such as antioxidants, dietary fibre and more generally fruits and vegetable intakes...
April 3, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29535193/motor-axon-navigation-relies-on-fidgetin-like-1-driven-microtubule-plus-end-dynamics
#4
Coralie Fassier, Amélie Fréal, Laïla Gasmi, Christian Delphin, Daniel Ten Martin, Stéphanie De Gois, Monica Tambalo, Christophe Bosc, Philippe Mailly, Céline Revenu, Leticia Peris, Susanne Bolte, Sylvie Schneider-Maunoury, Corinne Houart, Fatiha Nothias, Jean-Christophe Larcher, Annie Andrieux, Jamilé Hazan
During neural circuit assembly, extrinsic signals are integrated into changes in growth cone (GC) cytoskeleton underlying axon guidance decisions. Microtubules (MTs) were shown to play an instructive role in GC steering. However, the numerous actors required for MT remodeling during axon navigation and their precise mode of action are far from being deciphered. Using loss- and gain-of-function analyses during zebrafish development, we identify in this study the meiotic clade adenosine triphosphatase Fidgetin-like 1 (Fignl1) as a key GC-enriched MT-interacting protein in motor circuit wiring and larval locomotion...
May 7, 2018: Journal of Cell Biology
https://www.readbyqxmd.com/read/29527521/developing-a-return-to-work-intervention-for-breast-cancer-survivors-with-the-intervention-mapping-protocol-challenges-and-opportunities-of-the-needs-assessment
#5
Jean-Baptiste Fassier, Marion Lamort-Bouché, Guillaume Broc, Laure Guittard, Julien Péron, Sabrina Rouat, Julien Carretier, Béatrice Fervers, Laurent Letrilliart, Philippe Sarnin
Return to work (RTW) is an important step for breast cancer survivors (BCSs). However, they face many barriers that affect particularly women with low socioeconomic status (SES). Health care, workplace, and insurance actors lack knowledge and collaborate poorly. No intervention to date has proven effective to reduce social disparities in employment after breast cancer. The intervention mapping (IM) protocol is being used in France to develop, implement, and evaluate an intervention to facilitate and sustain RTW after breast cancer [ FAciliter et Soutenir le retour au TRAvail après un Cancer du Sein (FASTRACS) project]...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29456761/effects-of-a-telescopic-intramedullary-rod-for-treating-patients-with-osteogenesis-imperfecta-of-the-femur
#6
D L Rosemberg, E O Goiano, M Akkari, C Santili
Purpose: To introduce a new model of telescopic intramedullary rod (TIR), evaluate its effects on treating patients presenting with moderate and severe osteogenesis imperfecta (OI) and to compare the findings with those of other telescopic rods. Methods: A total of 21 patients (nine girls and 12 boys; mean age at first operation, 6.6 years, 1.52 to 13.18) who underwent 52 femoral operations were monitored during a mean of 9.96 years (3.39 to 14.54). Patient characteristics, telescoping rod capability and its complications were examined...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29444771/consumption-of-ultra-processed-foods-and-cancer-risk-results-from-nutrinet-sant%C3%A3-prospective-cohort
#7
RANDOMIZED CONTROLLED TRIAL
Thibault Fiolet, Bernard Srour, Laury Sellem, Emmanuelle Kesse-Guyot, Benjamin Allès, Caroline Méjean, Mélanie Deschasaux, Philippine Fassier, Paule Latino-Martel, Marie Beslay, Serge Hercberg, Céline Lavalette, Carlos A Monteiro, Chantal Julia, Mathilde Touvier
OBJECTIVE: To assess the prospective associations between consumption of ultra-processed food and risk of cancer. DESIGN: Population based cohort study. SETTING AND PARTICIPANTS: 104 980 participants aged at least 18 years (median age 42.8 years) from the French NutriNet-Santé cohort (2009-17). Dietary intakes were collected using repeated 24 hour dietary records, designed to register participants' usual consumption for 3300 different food items...
February 14, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29381920/corrective-osteotomy-with-retrograde-fassier-duval-nail-in-an-osteogenesis-imperfecta-patient-with-bilateral-genu-valgum-a-case-report
#8
Tsung-Yu Lin, Chen-Yu Yang, Shih-Chia Liu
RATIONALE: The treatment of osteogenesis imperfecta (OI) requires a multidisciplinary approach to maximize function and reduce fracture incidence. The aim of this case report was to discuss an alternative surgical approach to stabilize a corrective osteotomy using the Fassier Duval (FD) system in an OI patient. PATIENT CONCERNS: A 20-year-old OI woman presented with left thigh pain, gait disturbance, and bilateral genu valgus deformities. DIAGNOSES: Physical examination and standing radiographs revealed bilateral genu valgum with previous fixation implants in the femoral and the left tibia...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29247578/interventions-developed-with-the-intervention-mapping-protocol-in-the-field-of-cancer-a-systematic-review
#9
REVIEW
Marion Lamort-Bouché, Philippe Sarnin, Gerjo Kok, Sabrina Rouat, Julien Péron, Laurent Letrilliart, Jean-Baptiste Fassier
OBJECTIVES: The Intervention Mapping (IM) protocol provides a structured framework to develop, implement, and evaluate complex interventions. The main objective of this review was to identify and describe the content of the interventions developed in the field of cancer with the IM protocol. Secondary objectives were to assess their fidelity to the IM protocol and to review their theoretical frameworks. METHODS: Medline, Web of Science, PsycINFO, PASCAL, FRANCIS, and BDSP databases were searched...
April 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29126385/dilemma-between-health-and-environmental-motives-when-purchasing-animal-food-products-sociodemographic-and-nutritional-characteristics-of-consumers
#10
Sandrine Péneau, Philippine Fassier, Benjamin Allès, Emmanuelle Kesse-Guyot, Serge Hercberg, Caroline Méjean
BACKGROUND: Dietary guidelines in France give quantitative recommendations for intake of meat, fish and dairy products whereas consumers are increasingly concerned by the environmental impacts associated with the production of these foods. This potentially leads to consumer dilemmas when purchasing food products. The present study aimed at investigating the sociodemographic profiles of individuals reporting health and environmental dilemmas when purchasing meat, fish and dairy products, and comparing diet quality of individuals with and without dilemma...
November 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29051055/skeletal-impairment-in-pierson-syndrome-is-there-a-role-for-laminin%C3%AE-2-in-bone-physiology
#11
Camille Beaufils, Delphine Farlay, Irma Machuca-Gayet, Alice Fassier, Martin Zenker, Caroline Freychet, Edith Bonnelye, Aurélia Bertholet-Thomas, Bruno Ranchin, Justine Bacchetta
INTRODUCTION: Pierson syndrome is caused by a mutation of LAMB2, encoding for laminin β2. Clinical phenotype is variable but usually associates congenital nephrotic syndrome (CNS) and ocular abnormalities. Neuromuscular impairment has also been described. METHODS: We report on a 15-year old girl, suffering from Pierson Syndrome, who developed severe bone deformations during puberty. This patient initially displayed CNS and microcoria, leading to the clinical diagnosis of Pierson syndrome...
October 16, 2017: Bone
https://www.readbyqxmd.com/read/28927476/antioxidant-intake-from-diet-and-supplements-and-risk-of-digestive-cancers-in-middle-aged-adults-results-from-the-prospective-nutrinet-sant%C3%A3-cohort
#12
Manon Egnell, Philippine Fassier, Lucie Lécuyer, Rebeca Gonzalez, Laurent Zelek, Marie-Paule Vasson, Serge Hercberg, Paule Latino-Martel, Pilar Galan, Nathalie Druesne-Pecollo, Mélanie Deschasaux, Mathilde Touvier
Experimental studies suggest beneficial effects of antioxidants in digestive cancer prevention. However, epidemiological results are contrasting and few studies quantitatively assessed supplemental intake. This study aimed at investigating the associations between antioxidant intakes (dietary, supplemental and total) and digestive cancer risk. This prospective study included 38 812 middle-aged subjects (≥45 years) from the NutriNet-Santé cohort (2009-2016). Dietary data were collected using repeated 24 h records...
October 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28913916/red-and-processed-meat-intake-and-cancer-risk-results-from-the-prospective-nutrinet-sant%C3%A3-cohort-study
#13
RANDOMIZED CONTROLLED TRIAL
Abou Diallo, Mélanie Deschasaux, Paule Latino-Martel, Serge Hercberg, Pilar Galan, Philippine Fassier, Benjamin Allès, Françoise Guéraud, Fabrice H Pierre, Mathilde Touvier
The International Agency for Research on Cancer (WHO-IARC) classified red meat and processed meat as probably carcinogenic and carcinogenic for humans, respectively. These conclusions were mainly based on studies concerning colorectal cancer, but scientific evidence is still limited for other cancer locations. In this study, we investigated the prospective associations between red and processed meat intakes and overall, breast, and prostate cancer risk. This prospective study included 61,476 men and women of the French NutriNet-Santé cohort (2009-2015) aged ≥35 y and who completed at least three 24 hrs dietary records during the first year of follow-up...
January 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28903371/sociodemographic-and-economic-factors-are-associated-with-weight-gain-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#14
Philippine Fassier, Laurent Zelek, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Valentin Partula, Serge Hercberg, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Bernard Srour, Rebeca Gonzalez, Mélanie Deschasaux, Mathilde Touvier
PURPOSE: While many cancer patients are affected by weight loss, others tend to gain weight, which may impact prognosis and risk of recurrence and of second cancer. The aim of this prospective study was to investigate weight variation between before and after cancer diagnosis and socio-demographic, economic, lifestyle and clinical factors associated with moderate-to-severe weight gain. METHODS: 1051 incident cases of first primary cancer were diagnosed in the NutriNet-Santé cohort between 2009 and 2015...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28863872/decision-making-in-fecal-occult-blood-test-compliance-a-quali-quantitative-study-investigating-motivational-processes
#15
G Broc, B Denis, J-B Fassier, I Gendre, P Perrin, B Quintard
The qualitative-quantitative study investigates the co-existence of barriers and levers to FOBT screening in 5894 individuals reluctant to be screened, identifying operational motivational patterns that may increase screening compliance. Co-occurrence analysis was performed according to three motivational conditions (barriers, levers, or both).Cluster analysis then identified motivational predictors of effective screening. One quarter of the individuals who had refused screening nevertheless expressed at least one motivation towards FOBT...
December 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28820180/osteogenesis-imperfecta
#16
REVIEW
Joan C Marini, Antonella Forlino, Hans Peter Bächinger, Nick J Bishop, Peter H Byers, Anne De Paepe, Francois Fassier, Nadja Fratzl-Zelman, Kenneth M Kozloff, Deborah Krakow, Kathleen Montpetit, Oliver Semler
Skeletal deformity and bone fragility are the hallmarks of the brittle bone dysplasia osteogenesis imperfecta. The diagnosis of osteogenesis imperfecta usually depends on family history and clinical presentation characterized by a fracture (or fractures) during the prenatal period, at birth or in early childhood; genetic tests can confirm diagnosis. Osteogenesis imperfecta is caused by dominant autosomal mutations in the type I collagen coding genes (COL1A1 and COL1A2) in about 85% of individuals, affecting collagen quantity or structure...
August 18, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28799995/fassier-duval-telescopic-system-how-i-do-it
#17
Francois Fassier
The author describes step-by-step the technique for Fassier-Duval rodding of both femurs and tibiae in osteogenesis imperfecta. Preoperative evaluations and planning, postoperative care and place of bisphosphonates as explained. Emphasis is given on the different tricks to avoid intraoperative problems.
September 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28723699/intraoperative-bleeding-in-patients-with-osteogenesis-imperfecta-type-iii-treated-by-fassier-duval-femoral-rodding-analysis-of-risk-factors
#18
Pietro Persiani, Maria V Pesce, Lorena Martini, Filippo M Ranaldi, Patrizia D'Eufemia, Anna Zambrano, Mauro Celli, Ciro Villani
The surgical treatment of osteogenesis imperfecta (OI) is negatively influenced by clinical features such as osteoporosis, limb deformities and bone changes caused by bisphosphonate therapy. Blood loss during femoral nailing surgeries in patients with OI is a serious problem. Platelet anomalies have been associated with an elevation of the serum pyrophosphate originating from the platelets during clotting, even if the causality with the platelet dysfunction has not yet been established. To identify predictive risk factors regarding intraoperative bleeding, a retrospective analysis was conducted on 23 patients aged between 6 and 13 years, affected by OI type III, who were treated to correct femoral deformities or to perform an osteosynthesis for femoral shaft fractures, using the Fassier-Duval telescopic nail...
July 18, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28702767/erratum-to-development-of-the-return-to-work-obstacles-and-self-efficacy-scale-roses-and-validation-with-workers-suffering-from-a-common-mental-disorder-or-musculoskeletal-disorder
#19
Marc Corbière, Alessia Negrini, Marie-José Durand, Louise St-Arnaud, Catherine Briand, Jean-Baptiste Fassier, Patrick Loisel, Jean-Philippe Lachance
No abstract text is available yet for this article.
September 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28689307/long-term-follow-up-in-osteogenesis-imperfecta-type-vi
#20
P Trejo, T Palomo, K Montpetit, F Fassier, A Sato, F H Glorieux, F Rauch
This retrospective study on long-term outcomes in osteogenesis imperfecta type VI found that patients who received intravenous bisphosphonate treatment had an increase in lumbar spine areal bone mineral density, a higher final height z-score, and some reshaping of vertebral bodies. INTRODUCTION: Osteogenesis imperfecta (OI) type VI is an ultra-rare bone fragility disorder caused by recessive mutations in SERPINF1. Here, we describe long-term outcomes in OI type VI and compare the clinical phenotypes caused by different types of SERPINF1 mutations...
October 2017: Osteoporosis International
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