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Philippine Fassier, Laurent Zelek, Valentin Partula, Bernard Srour, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Mehdi Menai, Jean-Michel Oppert, Serge Hercberg, Mélanie Deschasaux, Mathilde Touvier
Physical activity (PA) but also reduced sedentary behavior may be associated with better prognosis and lower risk of recurrence in cancer patients. Our aim was to quantify the variations in PA and time spent sedentary between before and after diagnosis, relying on prospective data in French adults. We also investigated sociodemographic and lifestyle factors associated with these variations.Subjects (n = 942) were incident cancer cases diagnosed in the NutriNet-Santé cohort between 2009 and 2015. PA and sedentary behavior were prospectively collected with the 7-day short version of the IPAQ questionnaire every year since subjects' inclusion (i...
October 2016: Medicine (Baltimore)
Abou Diallo, Mélanie Deschasaux, Valentin Partula, Paule Latino-Martel, Bernard Srour, Serge Hercberg, Pilar Galan, Philippine Fassier, Françoise Guéraud, Fabrice H Pierre, Mathilde Touvier
Experimental results suggested that iron-induced lipid peroxidation may explain the direct associations observed between red/processed meat intakes and colorectal and breast cancer risk. However, epidemiological evidence is lacking. Thus, we investigated the association between dietary iron intake and breast cancer risk, and its potential modulation by an antioxidant supplementation and lipid intake. This prospective study included 4646 women from the SU.VI.MAX trial (daily low-dose antioxidants vs. placebo)...
October 12, 2016: Oncotarget
Kerstin Ekberg, Glenn S Pransky, Elyssa Besen, Jean-Baptise Fassier, Michael Feuerstein, Fehmidah Munir, Peter Blanck
Purpose Flexible work arrangements are growing in order to develop resource-efficient production and because of advanced technologies, new societal values, changing demographics, and globalization. The article aims to illustrate the emerging challenges and opportunities for work disability prevention efforts among workers in alternate work arrangements. Methods The authors participated in a year-long collaboration that ultimately led to an invited 3-day conference, "Improving Research of Employer Practices to Prevent Disability," held October 14-16, 2015, in Hopkinton, Massachusetts, USA...
October 4, 2016: Journal of Occupational Rehabilitation
Glenn S Pransky, Jean-Baptise Fassier, Elyssa Besen, Peter Blanck, Kerstin Ekberg, Michael Feuerstein, Fehmidah Munir
Introduction Many disability prevention strategies are focused on acute injuries and brief illness episodes, but there will be growing challenges for employers to manage circumstances of recurrent, chronic, or fluctuating symptoms in an aging workforce. The goal of this article is to summarize existing peer-review research in this area, compare this with employer discourse in the grey literature, and recommend future research priorities. Methods The authors participated in a year-long sponsored collaboration that ultimately led to an invited 3-day conference, "Improving Research of Employer Practices to Prevent Disability", held October 14-16, 2015, in Hopkinton, Massachusetts, USA...
October 4, 2016: Journal of Occupational Rehabilitation
Leonid S Grossman, Amber L Price, Eric T Rush, Jennifer L Goodwin, Maegen J Wallace, Paul W Esposito
BACKGROUND: To report a single-center surgical experience treating humeral deformity and fractures in children with osteogenesis imperfecta (OI) using the Fassier-Duval (FD) intramedullary elongating rods. METHODS: A retrospective review was conducted between December 2005 and July 2013 of all OI patients who underwent FD rodding with a minimum of 1-year follow-up. All patients were also being concurrently treated with bisphosphonates. RESULTS: Eighteen patients underwent internal fixation on a total of 35 humeri: 7 males and 11 females with an average age of 49 months...
September 22, 2016: Journal of Pediatric Orthopedics
Marc Corbière, Alessia Negrini, Marie-José Durand, Louise St-Arnaud, Catherine Briand, Jean-Baptiste Fassier, Patrick Loisel, Jean-Philippe Lachance
Introduction Common mental disorders (CMDs) and musculoskeletal disorders (MSDs) lead the list of causes for work absence in several countries. Current research is starting to look at workers on sick leave as a single population, regardless of the nature of the disease or accident. The purpose of this study is to report the validation of the Return to Work Obstacles and Self-Efficacy Scale (ROSES) for people with MSDs and CMDs, based on the disability paradigm. Methods From a prospective design, the ROSES' reliability and validity were investigated in a Canadian sample of workers on sick leave due to MSDs (n = 206) and CMDs (n = 157)...
August 25, 2016: Journal of Occupational Rehabilitation
Pauline Ducrot, Philippine Fassier, Caroline Méjean, Benjamin Allès, Serge Hercberg, Sandrine Péneau
Although home cooking has been associated with a lower body mass index in a few studies, no data exists on the motives behind food dish choices during home meal preparation and on their association with overweight. This study aimed to evaluate this association in 50,003 participants from the NutriNet-Santé cohort. Dimensions underlying the importance of 27 criteria possibly influencing dish choices were determined using an exploratory factor analysis. The association between dish choice motives and overweight (including obesity) was estimated using logistic regression models adjusted for sociodemographic and lifestyle characteristics...
2016: Nutrients
Khalid A Azzam, Eric T Rush, Bridget R Burke, Aleisha M Nabower, Paul W Esposito
BACKGROUND: Patients with osteogenesis imperfecta (OI) have significant burden of both fractures and bony deformities. The present approach to care in this disorder is a combination of surgical care with intramedullary rod fixation, cyclic bisphosphonate therapy, and rehabilitation with goal of maximizing patient function and quality of life. METHODS: Retrospective chart review identified 58 children with OI who had realignment osteotomies with Fassier-Duval (FD) intramedullary nailing of the lower extremity by a single surgeon...
July 2, 2016: Journal of Pediatric Orthopedics
D Hazard, J Bouix, M Chassier, E Delval, D Foulquié, T Fassier, Y Bourdillon, D François, A Boissy
In sheep, social reactivity and reactivity to humans are relevant behavioral responses that are used to investigate the behavioral adaptation of farm animals to various rearing conditions. Such traits were previously reported as heritable and associated with several QTLs. However, few behavior-related genotype by environment (G × E) interactions have been reported to date. The experiment was performed on 2,989 male and female lambs issued from 30 sires. Every sire had progeny reared under both intensive and extensive conditions...
April 2016: Journal of Animal Science
Amélie Fréal, Coralie Fassier, Barbara Le Bras, Erika Bullier, Stéphanie De Gois, Jamilé Hazan, Casper C Hoogenraad, François Couraud
UNLABELLED: The axon initial segment (AIS) is required for generating action potentials and maintaining neuronal polarity. Significant progress has been made in deciphering the basic building blocks composing the AIS, but the underlying mechanisms required for AIS formation remains unclear. The scaffolding protein ankyrin-G is the master-organizer of the AIS. Microtubules and their interactors, particularly end-binding proteins (EBs), have emerged as potential key players in AIS formation...
April 20, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Philippine Fassier, Anne-Sophie Chhim, Valentina A Andreeva, Serge Hercberg, Paule Latino-Martel, Camille Pouchieu, Mathilde Touvier
The Internet has become a major source of health and nutrition information. Little is known about the type of consulted websites (institutional v. non-institutional) and the tendency to discuss with a healthcare professional (HCP) the information found on the Internet. The aim of this cross-sectional study was to investigate health- and nutrition-related Internet use in a large French population-based study. Data were collected in 2013 using self-administered, web-based questionnaires from 42 113 participants of the NutriNet-Santé study (mean age=51·2 years, 76 % women)...
June 2016: British Journal of Nutrition
Sophie Fantoni-Quinton, Anne-Sophie Tellart, Evodie Cambier-Langrand, Jean Baptiste Fassier, Claire Mounier-Vehier
Since it allows a better quality of life, return to work must be considered ever since the early stages of the health care pathway following a cardiovascular disease. Seeing the occupational physician beforehand, so as to anticipate the return to work, is crucial. Dialogue between cardiologists, general practitioners and occupational physician, still observing medical confidentiality, must allow a better quality of return to work. Being recognized as a handicapped worker is a key element in the prevention of socio-professional exclusion...
May 2016: La Presse Médicale
Alfred Mansour, James Barsi, Todd Baldini, Gaia Georgopoulos
Antegrade telescoping rods have been introduced for use in pediatric patients with osteogenesis imperfecta (OI) to decrease the incidence of long-bone fractures and to correct and prevent deformities. Recent studies have documented failures of telescoping intramedullary rods due to inadequate distal fixation. The purpose of this study was to evaluate the pullout strength of distal fixation of the telescoping rod with and without synthetic calcium phosphate or polymethylmethacrylate (PMMA) augmentation. Four sets of 6 telescoping distal fixation rods were fixed according to standard insertion technique into an open-cell rigid-foam synthetic bone block simulating OI bone...
March 2016: Orthopedics
Norashikin Mahmud, Frederieke G Schaafsma, Jean-Baptiste Fassier, Jos H Verbeek, Michiel F Reneman
No abstract text is available yet for this article.
2016: Cochrane Database of Systematic Reviews
Elizabeth Ashby, Kathleen Montpetit, Reggie C Hamdy, Francois Fassier
BACKGROUND: The impact of humeral rodding on functional ability in children with osteogenesis imperfecta (OI) has not previously been reported. This article investigates this issue. METHODS: A retrospective chart review was conducted on 35 children with OI who underwent humeral rodding at our institution between 1995 and 2013. Fassier-Duval rods were inserted in 19 cases, K-wires in 13 cases, and Rush rods in 3 cases. Functional ability was assessed preoperatively and every year postoperatively using the self-care and mobility domains of the Pediatric Evaluation of Disability Inventory (PEDI)...
February 10, 2016: Journal of Pediatric Orthopedics
Elizabeth Ashby, Kathleen Montpetit, Reggie C Hamdy, François Fassier
BACKGROUND: The impact of corrective forearm surgery on functional ability in children with osteogenesis imperfecta (OI) has not previously been reported. This study addresses this issue. METHODS: A retrospective chart review was conducted on 19 children with OI who underwent 22 corrective forearm procedures between 1996 and 2013. Functional ability was assessed preoperatively and every year postoperatively using the Pediatric Evaluation of Disability Inventory (PEDI)...
February 2, 2016: Journal of Pediatric Orthopedics
Monia Barnat, Marie-Noelle Benassy, Laetitia Vincensini, Sylvia Soares, Coralie Fassier, Friedrich Propst, Annie Andrieux, Ysander von Boxberg, Fatiha Nothias
The microtubule-associated protein MAP1B plays a key role in axon regeneration. We investigated the role of GSK3-mediated MAP1B phosphorylation in local fine-tuning of neurite branching and the underlying microtubule (MT) dynamics. In wildtype adult dorsal root ganglia (DRG) neurons, MAP1B phosphorylation is locally reduced at branching points, and branching dynamics from growth cones and distal neurite shafts is increased upon GSK3 inhibition. While map1b-/- neurites, that display increased branching, are not affected by GSK3 inhibition, transfection of map1b-/- neurons with full-length map1b-cDNA restores the wildtype branching phenotype, demonstrating that MAP1B is a key effector downstream of GSK3...
April 2016: Molecular and Cellular Neurosciences
J-B Fassier, M Lamort-Bouché, P Sarnin, C Durif-Bruckert, J Péron, L Letrilliart, M-J Durand
BACKGROUND: Health promotion programs are expected to improve population health and reduce social inequalities in health. However, their theoretical foundations are frequently ill-defined, and their implementation faces many obstacles. The aim of this article is to describe the intervention mapping protocol in health promotion programs planning, used recently in several countries. METHODS: The challenges of planning health promotion programs are presented, and the six steps of the intervention mapping protocol are described with an example...
February 2016: Revue D'épidémiologie et de Santé Publique
Thomas Fassier, Antoine Duclos, Fatima Abbas-Chorfa, Sandrine Couray-Targe, T Eoin West, Laurent Argaud, Cyrille Colin
RATIONALE, AIMS AND OBJECTIVES: In the global context of population ageing, understanding and monitoring intensive care use by the elderly is a strategic issue. National-level data are needed to overcome sampling biases that often limit epidemiologic studies of the critically ill elderly. The objective of this study was to describe intensive care use for hospitalized elderly patients using secondary data from the French national hospital discharge database. METHOD: Structured assessment of the national database coverage and accuracy; cross-sectional analysis of hospitalizations including at least one admission in an intensive care unit (ICU) for patients aged ≥ 80 years from 1 January to 31 December 2009...
June 2016: Journal of Evaluation in Clinical Practice
Jean-Baptiste Fassier
No abstract text is available yet for this article.
January 2016: Scandinavian Journal of Work, Environment & Health
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