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https://www.readbyqxmd.com/read/28914249/visual-pedagogy-and-probiotics-for-hearing-impaired-children-a-pilot-study
#1
Amrita Sujlana, Ruchika Goyal, Parampreet Pannu, Shireen Opal, Palki Bansal
CONTEXT: Oral health care for children with special needs remains largely unmet. It is important that we should focus on preventive strategies for special children to help curtail and prevent oral diseases. AIM: This study aimed to assess the effect of visual pedagogy and probiotic mouth rinse on the periodontal health of hearing impaired children. MATERIALS AND METHODOLOGY: The study cohort consisted of twenty children with hearing impairment (HI) and 20 age-matched healthy children...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28911642/lactobacillus-pentosus-gmnl-77-inhibits-skin-lesions-in%C3%A2-imiquimod-induced-psoriasis-like-mice
#2
Yi-Hsing Chen, Chieh-Shan Wu, Ya-Husan Chao, Chi-Chen Lin, Hui-Yun Tsai, Yi-Rong Li, Yi-Zhen Chen, Wan-Hua Tsai, Yu-Kuo Chen
Psoriasis, which is regarded as a T-cell-mediated chronic inflammatory skin disease, is characterized by hyperproliferation and poor differentiation of epidermal keratinocytes. In this study, we aimed to determine the in vivo effect of a potentially probiotic strain, Lactobacillus pentosus GMNL-77, in imiquimod-induced epidermal hyperplasia and psoriasis-like skin inflammation in BALB/c mice. Oral administration of L. pentosus GMNL-77 significantly decreased erythematous scaling lesions. Real-time polymerase chain reaction showed that treatment with L...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28911536/biopharmaceutical-potentials-of-prosopis-spp-mimosaceae-leguminosa
#3
REVIEW
Santhaseelan Henciya, Prabha Seturaman, Arthur Rathinam James, Yi-Hong Tsai, Rahul Nikam, Yang-Chang Wu, Hans-Uwe Dahms, Fang Rong Chang
Prosopis is a commercially important plant genus, which has been used since ancient times, particularly for medicinal purposes. Traditionally, Paste, gum, and smoke from leaves and pods are applied for anticancer, antidiabetic, anti-inflammatory, and antimicrobial purposes. Components of Prosopis such as flavonoids, tannins, alkaloids, quinones, or phenolic compounds demonstrate potentials in various biofunctions, such as analgesic, anthelmintic, antibiotic, antiemetic, microbial antioxidant, antimalarial, antiprotozoal, antipustule, and antiulcer activities; enhancement of H(+), K(+), ATPases; oral disinfection; and probiotic and nutritional effects; as well as in other biopharmaceutical applications, such as binding abilities for tablet production...
January 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28901254/therapeutics-and-immunoprophylaxis-against-noroviruses-and-rotaviruses
#4
Souvik Ghosh, Yashpal Singh Malik, Nobumichi Kobayashi
Noroviruses and rotaviruses are important viral etiologies of severe gastroenteritis. Noroviruses are the primary cause of non-bacterial diarrheal outbreaks in humans, whilst rotaviruses are a major cause of childhood diarrhea. Although both enteric pathogens substantially impact human health and economies, there are no approved drugs against noroviruses and rotaviruses, so far. On the other hand, whilst the currently licensed rotavirus vaccines have been successfully implemented in over 100 countries, the most advanced norovirus vaccine has recently completed phase-I and II trials...
September 12, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28891576/in-vitro-assessment-of-the-ability-of-probiotics-blueberry-and-food-carbohydrates-to-prevent-s-pyogenes-adhesion-on-pharyngeal-epithelium-and-modulate-immune-responses
#5
Valentina Taverniti, Alessandro Dalla Via, Mario Minuzzo, Cristian Del Bo', Patrizia Riso, Hanne Frøkiær, Simone Guglielmetti
Group A streptococci (GAS) cause 20-30% of pediatric pharyngitis episodes, which are a major cause of ambulatory care visits. Therefore, a strategy to prevent GAS dissemination in children could significantly benefit public healthcare. Contextually, we assessed the possibility of employing alternative food-grade strategies to be used with the oral probiotic L. helveticus MIMLh5 for the prevention of pharyngeal infections. First, we demonstrated through an antagonism-by-exclusion assay that guaran may potentially prevent S...
September 11, 2017: Food & Function
https://www.readbyqxmd.com/read/28890155/antibiotic-induced-microbiota-perturbation-causes-gut-endocannabinoidome-changes-hippocampal-neuroglial-reorganization-and-depression-in-mice
#6
F Guida, F Turco, M Iannotta, D De Gregorio, I Palumbo, G Sarnelli, A Furiano, F Napolitano, S Boccella, L Luongo, M Mazzitelli, A Usiello, F De Filippis, F A Iannotti, F Piscitelli, D Ercolini, V de Novellis, V Di Marzo, R Cuomo, S Maione
The microbiota-gut-brain axis (MGBA) regulates the reciprocal interaction between chronic inflammatory bowel and psychiatric disorders. This interaction involves multiple pathways that are highly debated. We examined the behavioural, biochemical and electrophysiological alterations, as well as gut microbiota composition in a model of antibiotic-induced experimental dysbiosis. Inflammation of the small intestine was also assessed. Mice were exposed to a mixture of antimicrobials for 2weeks. Afterwards, they received Lactobacillus casei DG (LCDG) or a vehicle for up to 7days via oral gavage...
September 7, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28884476/probiotics-for-preventing-urinary-tract-infection-in-people-with-neuropathic-bladder
#7
REVIEW
Swee-Ling Toh, Claire L Boswell-Ruys, Bon San B Lee, Judy M Simpson, Kate R Clezy
BACKGROUND: Neuropathic or neurogenic bladder describes a process of dysfunctional voiding as the result of injury in the brain, spinal cord or nerves innervating the bladder. People with neuropathic bladder, such as from spinal cord injury (SCI), are at significant risk of morbidity from urinary tract infections (UTI). Effective methods to prevent UTI in people with SCI have been sought for many years. Probiotics (micro-organisms that exert beneficial health effects in the host) have been recommended for bacterial interference of the urological tract to reduce colonisation by uropathogen and to manage the dual problems of infection and antibiotic resistance...
September 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28874323/the-effect-of-probiotics-and-zinc-supplementation-on-the-immune-response-to-oral-rotavirus-vaccine-a-randomized-factorial-design-placebo-controlled-study-among-indian-infants
#8
Robin P Lazarus, Jacob John, E Shanmugasundaram, Anand K Rajan, S Thiagarajan, Sidhartha Giri, Sudhir Babji, Rajiv Sarkar, P Saravankumar Kaliappan, Srinivasan Venugopal, Ira Praharaj, Uma Raman, Meghana Paranjpe, Nicholas C Grassly, Edward P K Parker, Umesh D Parashar, Jacqueline E Tate, Jessica A Fleming, A Duncan Steele, Jayaprakash Muliyil, Asha M Abraham, Gagandeep Kang
BACKGROUND: Strategies are needed to improve oral rotavirus vaccine (RV), which provides suboptimal protection in developing countries. Probiotics and zinc supplementation could improve RV immunogenicity by altering the intestinal microbiota and immune function. METHODS: Infants 5weeks old living in urban Vellore, India were enrolled in a randomized, double-blind, placebo-controlled trial with a 4-arm factorial design to assess the effects of daily zinc (5mg), probiotic (10(10)Lactobacillus rhamnosus GG) or placebo on the immunogenicity of two doses of RV (Rotarix®, GlaxoSmithKline Biologicals) given at 6 and 10weeks of age...
September 2, 2017: Vaccine
https://www.readbyqxmd.com/read/28873648/soybean-protein-based-microparticles-for-oral-delivery-of-probiotics-with-improved-stability-during-storage-and-gut-resistance
#9
C González-Ferrero, J M Irache, C J González-Navarro
The present work describes the encapsulation of probiotics using a by-product as wall material and a process feasible to be scaled-up: coacervation of soybean protein concentrate (SPC) by using calcium salts and spray-drying. SPC was extracted from soybean flour, produced during the processing of soybean milk, by alkaline extraction following isoelectric precipitation. Two probiotic strains were selected for encapsulation (Lactobacillus plantarum CECT 220 and Lactobacillus casei CECT 475) in order to evaluate the ability of SPC to encapsulate and protect bacteria from stress conditions...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28873571/production-of-rs4-from-rice-starch-and-its-utilization-as-an-encapsulating-agent-for-targeted-delivery-of-probiotics
#10
Bilal Ahmad Ashwar, Asir Gani, Adil Gani, Asima Shah, Farooq Ahmad Masoodi
The research reported in this article is based on the hypothesis that crosslinking of starch can make it a potential wall material for targeted delivery of probiotics by altering its digestion. Three probiotic strains namely Lactobacillus casei, Lactobacillus brevis and Lactobacillus plantarum were microencapsulated with resistant starch. Encapsulation yield (%) of resistant starch microspheres was in the range of 43.01-48.46. The average diameter of resistant starch microparticles was in the range of 45.53-49...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28872975/characterization-of-inflammasome-components-in-pig-intestine-and-analysis-of-the-influence-of-probiotic-enterococcus-faecium-during-an-escherichia-coli-challenge
#11
Martina Kern, Jörg R Aschenbach, Karsten Tedin, Robert Pieper, Henriette Loss, Ulrike Lodemann
The aim of the present study was to investigate systematically the expression of inflammasome components in pig intestine and to analyze the influence of age and long-term supplementation with the probiotic Enterococcus faecium NCIMB 10415 (E. faecium). In order to examine probiotic effects on the inflammasomes during a challenge with pathogens, enterotoxigenic Escherichia coli (ETEC) and E. faecium were directly added to pig jejunum in Ussing chambers. The mRNA expression of inflammasome components generally decreased in an oral-aboral direction in intestinal tissues...
October 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28868181/oral-spore-based-probiotic-supplementation-was-associated-with-reduced-incidence-of-post-prandial-dietary-endotoxin-triglycerides-and-disease-risk-biomarkers
#12
Brian K McFarlin, Andrea L Henning, Erin M Bowman, Melody A Gary, Kimberly M Carbajal
AIM: To determine if 30-d of oral spore-based probiotic supplementation could reduce dietary endotoxemia. METHODS: Apparently healthy men and women (n = 75) were screened for post-prandial dietary endotoxemia. Subjects whose serum endotoxin concentration increased by at least 5-fold from pre-meal levels at 5-h post-prandial were considered "responders" and were randomized to receive either placebo (rice flour) or a commercial spore-based probiotic supplement [Bacillus indicus (HU36), Bacillus subtilis (HU58), Bacillus coagulans, and Bacillus licheniformis, and Bacillus clausii] for 30-d...
August 15, 2017: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/28861074/the-probiotic-combination-of-bifidobacterium-longum-subsp-infantis-cect-7210-and-bifidobacterium-animalis-subsp-lactis-bpl6-reduces-pathogen-loads-and-improves-gut-health-of-weaned-piglets-orally-challenged-with-salmonella-typhimurium
#13
Emili Barba-Vidal, Lorena Castillejos, Victor F B Roll, Gloria Cifuentes-Orjuela, José A Moreno Muñoz, Susana M Martín-Orúe
Probiotics have been demonstrated to be useful to enhance gut health and prevent gastrointestinal infections in humans. Additionally, some multi-strain probiotic combinations have been suggested to have greater efficacy than single strains. The objective of this study is to demonstrate the potential of a combination of the probiotic strains: Bifidobacterium longum subsp. infantis CECT 7210 (brand name B. infantis IM1(®)) and B. animalis subsp. lactis BPL6 to enhance gut health and to ameliorate the outcome of a Salmonella challenge using a weaning piglet model...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28852985/comparison-of-acyclovir-and-multistrain-lactobacillus-brevis-in-women-with-recurrent-genital-herpes-infections-a-double-blind-randomized-controlled-study
#14
Amir Hossein Mohseni, Sedigheh Taghinezhad-S, Hossein Keyvani, Narges Ghobadi
We performed a randomized double-blind controlled trial to compare the efficacy and safety of multistrain probiotic and acyclovir in women patients with recurrent genital herpes simplex virus type 2 (HSV-2) infections. Eighty-one patients enrolled in the study were being treated with multistrain Lactobacillus brevis one vaginal capsule every 12 h and oral acyclovir 400 mg twice daily for 6 months. Of 53 patients who completed both treatment courses, no important differences were identified between acyclovir and probiotic for the primary and secondary efficacy endpoint, resolution of episode (hazard ratio, 0...
August 30, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28846472/the-current-state-of-food-allergy-therapeutics
#15
Meng Chen, Michael Land
The prevalence of IgE mediated food allergy is an increasing public health concern. The current standard of treatment is strict avoidance of the offending food(s). There are no FDA approved treatments for food allergy. This review will provide an overview of strategies currently under investigation for the treatment of food allergy. The main focus of research has been directed at various forms of immunotherapy, including oral, sublingual and epicutaneous delivery routes. While oral immunotherapy (OIT) has shown the greatest promise for efficacy in terms of amount of protein that can be ingested, it has also demonstrated less tolerability and a less favorable safety profile as compared to sublingual immunotherapy (SLIT) and epicutaneous immunotherapy (EPIT), which offers the least protection but has the best safety and tolerability profile...
August 28, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28841659/pre-treatment-with-lactobacillus-plantarum-prevents-severe-pathogenesis-in-mice-infected-with-leptospira-interrogans-and-may-be-associated-with-recruitment-of-myeloid-cells
#16
Hari-Hara Potula, Luciana Richer, Catherine Werts, Maria Gomes-Solecki
Recent estimates on global morbidity and mortality caused by Leptospirosis point to one million cases and almost 60,000 deaths a year worldwide, especially in resource poor countries. We analyzed how a commensal probiotic immunomodulator, Lactobacillus plantarum, affects Leptospira interrogans pathogenesis in a murine model of sub-lethal leptospirosis. We found that repeated oral pre-treatment of mice with live L. plantarum restored body weight to normal levels in mice infected with L. interrogans. Pre-treatment did not prevent L...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28840820/ecological-therapeutic-opportunities-for-oral-diseases
#17
Anilei Hoare, Philip D Marsh, Patricia I Diaz
The three main oral diseases of humans, that is, caries, periodontal diseases, and oral candidiasis, are associated with microbiome shifts initiated by changes in the oral environment and/or decreased effectiveness of mucosal immune surveillance. In this review, we discuss the role that microbial-based therapies may have in the control of these conditions. Most investigations on the use of microorganisms for management of oral disease have been conducted with probiotic strains with some positive but very discrete clinical outcomes...
August 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28840678/-pathomechanism-and-treatment-of-gut-microbiota-dysbiosis-in-chronic-kidney-disease-and-interventional-effects-of-chinese-herbal-medicine
#18
REVIEW
Wen-Bei Han, Ying-Lu Liu, Yi-Gang Wan, Wei Sun, Yue Tu, Jing-Jing Yang, Wei Wu, Wei-Ming He, Jian Yao
The gut microbiota dysbiosis is one of the risk factors in the progression from the advanced chronic kidney disease(CKD)to uremia, characterized by the reduction of probiotics and the increase of opportunistic pathogens including urease-related microbes, endotoxin-related microbes and toxin-related microbes, which can produce uremic toxins. According to the core point of "the gut-kidney axis" theory and "the chronic kidney disease-colonic axis" concept, the gut microbiota dysbiosis aggravates renal damage by accumulating uremic toxins and inducing the systemic micro-inflammation...
July 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28837512/the-management-of-acute-pancreatitis-in-the-pediatric-population-a-clinical-report-from-the-naspghan-pancreas-committee
#19
Maisam Abu-El-Haija, Soma Kumar, J Antonio Quiros, Keshawadhana Balakrishnan, Bradley Barth, Samuel Bitton, John F Eisses, Elsie Jazmin Foglio, Victor Fox, Denease Francis, A Jay Freeman, Tanja Gonska, Amit S Grover, Sohail Z Husain, Rakesh Kumar, Sameer Lapsia, Tom Lin, Quin Y Liu, Asim Maqbool, Zachary M Sellers, Flora Szabo, Aliye Uc, Steven L Werlin, Veronique D Morinville
BACKGROUND: While the incidence of acute pancreatitis (AP) in children is increasing, management recommendations rely on adult published guidelines. Pediatric-specific recommendations are needed. METHODS: The NASPGHAN Pancreas committee performed a MEDLINE review using several pre-selected key terms relating to management considerations in adult and pediatric AP. The literature was summarized, quality of evidence reviewed, and statements of recommendations developed...
August 23, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28837361/role-of-honey-in-topical-and-systemic-bacterial-infections
#20
Muhammad Barkaat Hussain
BACKGROUND: The development of bacterial resistance to antibiotics has made it more difficult and expensive to treat infections. Honey is getting worldwide attention as a topical therapeutic agent for wound infections and potential future candidate for systemic infections. OBJECTIVES: The purpose of this review was to summarise different antibacterial bio-active compounds in honey, their synergistic interaction and their clinical implications in topical and systemic infections...
August 24, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
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