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https://www.readbyqxmd.com/read/29332228/comparative-evaluation-of-the-aqueous-humor-proteome-of-primary-angle-closure-and-primary-open-angle-glaucomas-and-age-related-cataract-eyes
#1
Inderjeet Kaur, Jasbir Kaur, K Sooraj, Sandeep Goswami, Rohit Saxena, Virander Singh Chauhan, Ramanjit Sihota
PURPOSE: To analyze and compare the total proteome of aqueous humor (AH) from patients having primary angle closure glaucoma (PACG), primary open angle glaucoma (POAG) and age-related cataract. MATERIALS AND METHODOLOGY: Aqueous humor was collected from age-matched PACG, POAG and cataract patients who underwent surgery, and it was immediately stored at - 80 °C until analysis. From each sample, 25 µg of total protein was subjected to trypsin digestion and subsequently LC-MS/MS analysis was performed for the deep proteome analysis...
January 13, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29331455/femtosecond-laser-cataract-surgery-in-pediatric-patients
#2
Claudia Corredor-Ortega, Roberto Gonzalez-Salinas, María José Montero, Rocío González-Flores, Allan Collura-Merlier, Guadalupe Cervantes-Coste, Erick Mendoza-Schuster, Cecilio Velasco-Barona
No abstract text is available yet for this article.
January 10, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29331293/toric-lens-implantation-in-cataract-surgery-automated-versus-manual-horizontal-axis-marking-analysis-of-50%C3%A2-cases
#3
M Raucau, H El Chehab, E Agard, C Lagenaite, C Dot
SUBJECT: The main objective of our study was to evaluate the contribution of automated conjunctival registration in the alignment of toric intraocular lenses by comparing automated registration optimized with Callisto® to manual marking of the horizontal axis. MATERIALS AND METHODS: We performed a prospective, descriptive, monocentric study on patients undergoing cataract surgery with a toric intraocular lens (Asphina 709 Zeiss), performed by a surgeon with good experience in toric implants, between September 2016 and March 2017...
January 10, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29329947/-pseudoexfoliation-syndrome-and-pseudoexfoliation-glaucoma
#4
REVIEW
C Schweitzer
Pseudoexfoliation syndrome is an age-related systemic disease that mainly affects the anterior structures of the eye. Despite a worldwide distribution, reported incidence and prevalence of this syndrome vary widely between ethnicities and geographical areas. The exfoliative material is composed mainly of abnormal cross-linked fibrils that accumulate progressively in some organs such as the heart, blood vessels, lungs or meninges, and particularly in the anterior structures of the eye. The exact pathophysiological process still remains unclear but the association of genetic and environmental factors are thought to play a role in the development and progressive extracellular accumulation of exfoliative material...
January 9, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29326317/comparative-analysis-of-the-safety-and-efficacy-of-intracameral-cefuroxime-moxifloxacin-and-vancomycin-at-the-end-of-cataract-surgery-a-meta-analysis
#5
Randy C Bowen, Andrew Xingyu Zhou, Sailaja Bondalapati, Thomas W Lawyer, Karisa B Snow, Patrick R Evans, Tyler Bardsley, Mary McFarland, Matthew Kliethermes, Dallas Shi, Christina A Mamalis, Tom Greene, Christopher J Rudnisky, Balamurali Krishna Ambati
BACKGROUND: Current practice methods are unclear as to the most safe and effective prophylactic pharmacotherapy and method of delivery to reduce postoperative endophthalmitis occurrence. METHODS: A systematic review and meta-analysis using Meta-analysis of Observational Studies in Epidemiology guidelines was performed to compare the efficacy of intracameral cefuroxime, moxifloxacin and vancomycin in preventing postphacoemulsification cataract surgery endophthalmitis...
January 11, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29325387/-clinical-effects-of-pediatric-penetrating-keratoplasty-for-congenital-corneal-opacity
#6
S W Li, C Liu, T H Chen, J H Ning, T Zhang, F J Lyu, M Xu
Objective: To report the clinical results of pediatric penetrating keratoplasty (PKP) in patients under 3 years old with congenital corneal opacity. Methods: Retrospective study. Sixteen eyes of 12 patients who were treated with PKP in Aier Eye Hospital Group from June 2009 to December 2016 were enrolled in this study. All the patients were diagnosed as congenital corneal opacities: 8 cases (11 eyes) with Peter's anomaly I, 2 cases (3 eyes) with sclerocornea, and 2 cases (2 eyes) with corneal dermoid tumor combined with iris synechia...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29323612/pharmacokinetic-analysis-of-intraocular-penetration-of-latanoprost-solutions-with-different-preservatives-in-human-eyes
#7
Yuko Sekine, Marie Shimada, Shoko Satake, Masato Okubo, Akihiro Hisaka, Tadashi Hara, Megumi Honjo, Makoto Aihara
OBJECTIVES: To investigate the effect of excipients on latanoprost penetration into the aqueous humor with clinically available 6 products with different solutions mainly in the types and concentrations of preservatives. METHODS: In 363 patients with cataracts, we instilled 1 latanoprost drop in 1 eye before surgery. The drop was randomly selected by brand name product (A) and 5 generic products (B-F) composed with different excipients. B contains similar excipients to A...
January 11, 2018: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29322749/time-reversed-ultrasonically-encoded-optical-focusing-through-highly-scattering-ex-vivo-human-cataractous-lenses
#8
Yan Liu, Yuecheng Shen, Haowen Ruan, Frank L Brodie, Terence T W Wong, Changhuei Yang, Lihong V Wang
Normal development of the visual system in infants relies on clear images being projected onto the retina, which can be disrupted by lens opacity caused by congenital cataract. This disruption, if uncorrected in early life, results in amblyopia (permanently decreased vision even after removal of the cataract). Doctors are able to prevent amblyopia by removing the cataract during the first several weeks of life, but this surgery risks a host of complications, which can be equally visually disabling. Here, we investigated the feasibility of focusing light noninvasively through highly scattering cataractous lenses to stimulate the retina, thereby preventing amblyopia...
January 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29320451/the-pathogenesis-of-staphylococcus-aureus-eye-infections
#9
REVIEW
Richard J O'Callaghan
Staphylococcus aureus is a major pathogen of the eye able to infect the tear duct, eyelid, conjunctiva, cornea, anterior and posterior chambers, and the vitreous chamber. Of these infections, those involving the cornea (keratitis) or the inner chambers of the eye (endophthalmitis) are the most threatening because of their potential to cause a loss in visual acuity or even blindness. Each of these ocular sites is protected by the constitutive expression of a variety of antimicrobial factors and these defenses are augmented by a protective host response to the organism...
January 10, 2018: Pathogens
https://www.readbyqxmd.com/read/29317798/visual-outcomes-efficacy-and-surgical-complications-associated-with-intracameral-phenylephrine-1-0-ketorolac-0-3-administered-during-cataract-surgery
#10
Eric D Rosenberg, Alanna S Nattis, David Alevi, Rachel L Chu, Joseph Bacotti, Ronald J LoPinto, Gerald D'Aversa, Eric D Donnenfeld
Aim: The purpose of this study was to compare visual outcomes, surgical time, and perioperative surgical complications after intracameral use of either phenylephrine/ketorolac (P/K) or epinephrine (Epi) during cataract surgery. Methods: This was a single-center, retrospective case review of patients undergoing cataract surgery from August to November 2015. Of the 641 eyes of 389 patients who underwent cataract surgery, 260 eyes were administered phenylephrine 1...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29317238/gender-differences-in-mrna-expression-of-aquaporin-8-and-glutathione-peroxidase-in-cataractous-lens-following-intake-of-an-antioxidant-supplement
#11
Rijo Hayashi, Shimmin Hayashi, Miki Sakai, Kiyomi Arai, Makoto Chikuda, Shigeki Machida
Antioxidants can decrease oxidative damage and prevent age-related ocular disease. Our previous investigation on human aqueous humor following intake of a lutein-containing antioxidant supplement reported an increase in the scavenging activity of superoxide in both genders and an increase in the amount of hydrogen peroxide (H2O2) in females. Aquaporin 8 (AQP8) is a diffusion facilitator of H2O2 and glutathione peroxidase (Gpx) is a H2O2 scavenging enzyme. The correlation between AQP8 and Gpx may be the key to determining how oxidative stress in the aqueous humor affects the lens after intake of antioxidant supplements...
January 6, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29316890/risk-factors-of-postoperative-pulmonary-complications-in-patients-with-asthma-and-copd
#12
Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Yumi Kaneko, Kazuyoshi Kuwano
BACKGROUND: Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to evaluate perioperative management using new inhalant drugs in patients with obstructive pulmonary diseases. METHODS: April 2014 through March 2015, 346 adult patients with pulmonary diseases (257 asthma, 89 chronic obstructive pulmonary disease (COPD)) underwent non-pulmonary surgery except cataract surgery in our university hospital...
January 9, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29315441/ray-tracing-analysis-of-the-corneal-power-from-scheimpflug-data
#13
Thomas Olsen, Peter Jeppesen
PURPOSE: To describe a method by which mapped corneal elevation data can be used for ray-tracing analysis of the effective corneal power. METHODS: Mapped elevation data of the front and back surface of the cornea exported by a clinical Scheimpflug camera was triangulated into a polygonal format and imported into a commercial optical engineering software. The focal length of the cornea was determined by exact ray tracing analysis of the distance giving the sharpest point spread function (PSF) at the selected image plane...
January 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29315437/evaluation-of-femtosecond-laser-versus-manual-clear-corneal-incisions-in-cataract-surgery-using-spectral-domain-optical-coherence-tomography
#14
Xiaogang Wang, Zhe Zhang, Xiaoyan Li, Lisha Xie, Haining Zhang, Douglas D Koch, Li Wang, Suhua Zhang
PURPOSE: To investigate the wound healing changes of clear corneal incisions performed with a femtosecond laser or a steel bevel knife in cataract surgery using spectral-domain optical coherence tomography. METHODS: Prospectively, consecutive patients undergoing either femtosecond laser-assisted cataract surgery (femtosecond laser group) using the LenSx laser (Alcon Laboratories, Inc., Fort Worth, TX) or traditional cataract surgery using steel blades (control group) were enrolled...
January 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29310952/-corneal-perforation-following-cataract-surgery-with-anterior-chamber-intraocular-lens-due-to-adherent-leukoma
#15
M Khmamouche, R Zerrouk, Y Abaloune, A El Khoyaali, F El Asri, K Reda, O Abdelbare
No abstract text is available yet for this article.
January 5, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29305324/real-world-outcomes-in-patients-with-neovascular-age-related-macular-degeneration-treated-with-intravitreal-vascular-endothelial-growth-factor-inhibitors
#16
REVIEW
Hemal Mehta, Adnan Tufail, Vincent Daien, Aaron Lee, Vuong Nguyen, Mehmet Ozturk, Daniel Barthelmes, Mark C Gillies
Clinical trials identified intravitreal vascular endothelial growth factor inhibitors (anti-VEGF agents) have the potential to stabilise or even improve visual acuity outcomes in neovascular age-related macular degeneration (AMD), a sight-threatening disease. Real-world evidence allows us to assess whether results from randomised controlled trials can be applied to the general population. We describe the development of global registries, in particular the Fight Retinal Blindness! registry that originated in Australia, the United Kingdom AMD Electronic Medical Records User Group and the IRIS registry in the USA...
January 2, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29305312/population-based-incidence-of-intraocular-lens-exchange-in-olmsted-county-minnesota
#17
Erick D Bothun, Lilian C B Cavalcante, David O Hodge, Sanjay V Patel
PURPOSE: To determine the population-based incidence of pseudophakic intraocular lens exchange in Olmsted County, Minnesota. DESIGN: Retrospective review of a population-based cohort. METHODS: Patients undergoing pseudophakic intraocular lens exchange in Olmsted County, MN between January 1, 1986 and December 31, 2016, were identified from the Rochester Epidemiology Project medical record linkage system. Indications and outcomes were determined, and the incidence rate was calculated as cases per 1,000,000 person-years...
January 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29304817/catquest-9sf-questionnaire-validation-of-malay-and-chinese-language-versions-using-rasch-analysis
#18
Tassha Hilda Adnan, Mokhlisoh Mohamed Apandi, Haireen Kamaruddin, Mohamad Aziz Salowi, Kian Boon Law, Jamaiyah Haniff, Pik Pin Goh
BACKGROUND: Catquest questionnaire was originally developed in Swedish to measure patients' self-assessed visual function to evaluate the benefit of cataract surgery. The result of the Rasch analysis leading to the creation of the nine-item short form of Catquest, (Catquest-9SF), and it had been translated and validated in English. The aim is therefore to evaluate the translated Catquest-9SF questionnaire in Malay and Chinese (Mandarin) language version for measuring patient-reported visual function among cataract population in Malaysia...
January 5, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29304077/ideal-parameters-for-femto-second-laser-assisted-anterior-capsulotomy-animal-studies
#19
Min-Ji Kang, Yong-Eun Lee, Jun-Sub Choi, Choun-Ki Joo
In femtosecond laser-assisted cataract surgery, the parameter such as horizontal spot spacing and energy level can be adjusted. Although there have been several studies reported on various laser systems, showing the effects of varying energy levels and horizontal spot spacing on lens capsulotomy cut edges, none have been reported on the Catalys laser system (Abbott Medical Optics, Inc., Santa Ana, CA). The aim of this study is to evaluate, using scanning electron microscopy (SEM), the quality of the cut edges of the laser lens capsulotomy obtained using the Catalys Laser System, using different horizontal spot spacing and energy levels, and to determine the ideal parameters based on SEM results...
2018: PloS One
https://www.readbyqxmd.com/read/29303887/correlation-between-postoperative-central-corneal-thickness-and-endothelial-damage-after-cataract-surgery-by-phacoemulsification
#20
Jean Marc Perone, Mathilde Boiche, Louis Lhuillier, Francis Ameloot, Shamour Premy, Anne-Laure Jeancolas, Christophe Goetz, Estelle Neiter
PURPOSE: To study the correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification. METHODS: Eighty-five eyes of 85 consecutive patients with mild cataract (up to C5, N4, and P5: per LOCS III classification) were included in a prospective study from September 2014 to November 2014. Eighty-five eyes were necessary to obtain a precision of 0.15 for computation of the Pearson correlation coefficient...
January 4, 2018: Cornea
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