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https://www.readbyqxmd.com/read/28926882/-diagnostic-criteria-of-demodex-blepharitis
#1
L Y Liang, J Li, Y Liu
Demodex infestation is a common cause of blepharitis and now is drawing more and more attention from clinicians. Demodex mite is the most common age-related ectoparasite of human being and may be detected from asymptomatic normal population. Furthermore, the pathogenesis of demodicosis remains unclear. Therefore, the commonly accepted diagnostic criteria of demodex infestation related blepharitis have not been established. Herein, we summarize the related studies about ocular demodicosis and comment the debates about the diagnosis of the disease...
September 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28922088/semifluorinated-alkane-eye-drops-for-treatment-of-dry-eye-disease-due-to-meibomian-gland-disease
#2
Philipp Steven, Albert J Augustin, Gerd Geerling, Thomas Kaercher, Florian Kretz, Kathleen Kunert, Johannes Menzel-Severing, Norbert Schrage, Wolfgang Schrems, Sonja Krösser, Michael Beckert, Elisabeth M Messmer
PURPOSE: Meibomian gland disease is generally accepted as the leading cause for evaporative dry eye disease (DED). In a previous study, perfluorohexyloctane, a semifluorinated alkane, has been demonstrated to significantly increase tear film breakup time and to reduce corneal fluorescein staining in patients with evaporative DED, thereby vastly reducing dry eye-related symptoms. This study was set up to evaluate perfluorohexyloctane in a larger population of patients with Meibomian gland dysfunction...
September 18, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28922018/tacrolimus-ointment-for-refractory-posterior-blepharitis
#3
Fernando Eiji Sakassegawa-Naves, Helena Maria Moraes Ricci, Bernardo Kaplan Moscovici, Daniela Akemi Miyamoto, Brenda Biagio Chiacchio, Ricardo Holzchuh, Ruth Muyuki Santo, Richard Yudi Hida
PURPOSE: This prospective, randomized, double-blind interventional case series was designed to evaluate the short-term efficacy of 0.03% tacrolimus ointment as a new therapeutic approach for refractory cases of posterior blepharitis. METHODS: Forty eyes (20 patients) with posterior blepharitis refractory to previous treatment were randomized. Eighteen eyes (9 patients) were treated with 0.03% tacrolimus ointment and 20 eyes (10 patients) with placebo ointment twice daily...
September 18, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28920471/unilateral-blepharitis-with-fine-follicular-scaling
#4
Alin Laurentiu Tatu, Violeta Corina Cristea
No abstract text is available yet for this article.
September 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28919243/drugs-do-we-need-them-applications-of-non-pharmaceutical-therapy-in-anterior-eye-disease-a-review
#5
REVIEW
Priyanka Mandal, Mohammad A Khan, Sunil Shah
Natural products have been in use long before the introduction of modern drug therapies and are still used in various communities worldwide for the treatment of anterior eye disease. The aim of this review is to look at the current non-pharmaceutical modalities that have been tried and assess the body of existing evidence behind them. This includes alternative medicine, existing non-pharmaceutical therapy and more recent low and high tech solutions. A detailed search of all available databases including MEDLINE, Pubmed and Google was made to look for English-language studies for complementary and alternative treatment modalities (CAM), natural therapies and new modalities for anterior eye disease such as blepharitis, dry eye and microbial keratitis...
September 14, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28902017/ocular-demodicosis-as-a-potential-cause-of-ocular-surface-inflammation
#6
Xiaohui Luo, Jing Li, Chuan Chen, Scheffer Tseng, Lingyi Liang
Among different species of mites, Demodex folliculorum and Demodex brevis are the only 2 that affect the human eye. Because demodicosis is highly age-dependent and can be found in asymptomatic adults, the pathogenicity of these mites has long been debated. In this study, we summarize our research experience including our most recent study regarding Demodex infestation as a potential cause of ocular inflammatory diseases. Specifically, we describe the pathogenesis of demodicosis and then discuss the results of work investigating the associations and relationships between ocular demodicosis and blepharitis, meibomian gland diseases, and keratitis, in turn...
September 7, 2017: Cornea
https://www.readbyqxmd.com/read/28880989/blepharitis-with-facial-numbness-and-ocular-pain
#7
Jennifer C Fan Gaskin, Caroline O L Wong, Brent J Gaskin
No abstract text is available yet for this article.
September 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28860908/meibography-for-eyes-with-posterior-blepharitis
#8
Abdulrahman AlDarrab, Mohammed Alrajeh, Adel H Alsuhaibani
PURPOSE: To study the effect of posterior blepharitis on meibomian glands using infrared meibography and to correlate the results with tear film parameters. METHODS: This is a prospective cohort study. The study included eyes from two groups: 86 eyes of healthy volunteers' eyes and 72 eyes with posterior blepharitis. Participants were examined, and diagnosis of posterior blepharitis was achieved clinically based on signs of posterior blepharitis. Clinical assessment of dryness was performed including slit lamp examination looking for signs of posterior blepharitis, tear breakup time (TBUT), superficial punctate keratopathy (SPK), Schirmer II test (with anesthesia) and meibum score...
July 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28859743/demodicosis-treatment-with-systemic-ivermectin
#9
Manuel Coelho da Rocha, Ana Rita Travassos, Luís Uva, Hortênsia Sequeira, Paulo Filipe
A 23-year-old white man presented to our dermatology department complaining of pruriginous and erythematous papulopustules on the right cheek that had developed 6 months previously. He had a history of chronic blepharitis, complicated by a recurrent hordeolum that had been treated with warm compresses and topical antibiotic ointment (chloramphenicol) for approximately 2 years. The patient had oily skin and atopy (allergic rhinitis) and did not experience photosensitivity or flushing or have previous exposure to immunosuppressants or topical/systemic corticosteroids...
2017: Skinmed
https://www.readbyqxmd.com/read/28858192/bleb-related-endophthalmitis-after-use-of-the-invitria-injection-guide
#10
Alex J Baneke, Georgios Vakros, Vik Sharma, Sui Chien Wong
PURPOSE: To present the case of a patient who developed bleb-related endophthalmitis after an intravitreal injection using the InVitria injection guide, alongside a review of the literature on bleb-related endophthalmitis. METHODS: Our case is presented in context of the current literature on bleb-related endophthalmitis. RESULTS: Bleb-related endophthalmitis occurs in up to 2% of eyes within 5 years of filtering glaucoma surgery. Risk factors include bleb leakage, use of anti-fibrinolytic agents, blepharitis, hypotony, and nasolacrimal duct obstruction...
August 28, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28855579/expression-of-il-33-in-ocular-surface-epithelium-induces-atopic-keratoconjunctivitis-with-activation-of-group-2-innate-lymphoid-cells-in-mice
#11
Yasutomo Imai, Yuka Hosotani, Hiroto Ishikawa, Koubun Yasuda, Makoto Nagai, Orie Jitsukawa, Fumi Gomi, Kenji Nakanishi, Tomohiro Yoshimoto, Takahiro Nakamura, Kiyofumi Yamanishi
In a transgenic mouse line hK14mIL33tg, with the expression of interleukin-33 (IL-33) driven by a keratin 14 promoter, keratoconjunctivitis developed spontaneously between 18 and 22 weeks of age under specific-pathogen-free conditions. These mice showed blepharitis and corneal impairments, and the histology revealed epithelial thickening in the conjunctiva and the cornea with infiltration of eosinophils, mast cells and basophils. IL-5, IL-13 and CCL11 were abundant in lacrimal fluid in the mice, and the gene expressions of IL-4, IL-5, IL-13, IL-33, Prg2 and Mmcp8 were significantly increased in the cornea...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28853982/outcomes-of-two-surgical-techniques-for-major-trichiasis-treatment
#12
Lucieni Cb Ferraz, Roberta Lrs Meneghim, Alicia Galindo-Ferreiro, Ana Cv Wanzeler, Michelli M Saruwatari, Larissa H Satto, Carlos R Padovani, Silvana A Schellini
The purpose of this article is to analyze the outcomes of two surgical techniques to treat major trichiasis. A retrospective chart review of 67 patients (89 eyelids) with major trichiasis was performed who underwent surgical treatment using one of two techniques: intermarginal split lamella with graft (ISLG group) or lid lamella resection (LLR group). There were 30 lids in the ISLG group with mean patient age of 71.8 years and 63.3% were females. There were 59 lids in the LLR group with mean patient age of 72...
August 30, 2017: Orbit
https://www.readbyqxmd.com/read/28830451/bacterial-pathogens-associated-with-external-ocular-infections-alongside-eminent-proportion-of-multidrug-resistant-isolates-at-the-university-of-gondar-hospital-northwest-ethiopia
#13
Ergibnesh Getahun, Baye Gelaw, Abate Assefa, Yared Assefa, Anteneh Amsalu
BACKGROUND: External ocular infection is a public health problem in Ethiopia. The aim of this study was to determine the prevalence and antimicrobial susceptibility pattern of external ocular bacterial infections. METHODS: A cross sectional study was conducted at the University of Gondar Hospital among patients seeking health services at the Department of Ophthalmology from January to April, 2016. All patients with suspected external ocular infections were examined under slit lamp microscope...
August 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28791059/risk-factors-for-pterygium-in-ilam-province-iran
#14
Parviz Malekifar, Hamed Esfandiari, Nazanin Behnaz, Fatemeh Javadi, Sima Azish, Mohammad Ali Javadi, Masumeh Kalantarion
PURPOSE: To evaluate the risk factors for pterygium in the dry, high altitude province of Ilam, Iran. METHODS: The study included patients who presented to ophthalmology clinic. The patients were divided into two groups: 210 diagnosed with pterygium or pinguecula (unilateral or bilateral), and 210 healthy controls. Demographic variables, living environment, disease type, disease laterality, family history of pterygium as well as history of smoking, working outdoors, baking, welding, ocular conditions (trachoma keratopathy, glaucoma, refractive error, and dry eye), use of glasses, ultraviolet light exposure, and systemic conditions were collected from both groups and compared for risk assessment...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28747952/human-permanent-ectoparasites-recent-advances-on-biology-and-clinical-significance-of-demodex-mites-narrative-review-article
#15
REVIEW
Dorota Litwin, WenChieh Chen, Ewa Dzika, Joanna Korycińska
BACKGROUND: Demodex is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation between Demodex mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Clinical observations indicate a primary form of human Demodex infection. The aim of this review was to highlight the biological aspects of Demodex infestation and point out directions for the future research...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28741159/sebaceous-gland-carcinoma-of-the-ocular-adnexa-variability-in-clinical-and-histological-appearance-with-analysis-of-immunohistochemical-staining-patterns
#16
Eva Janine Schmitz, Martina C Herwig-Carl, Frank G Holz, Karin U Loeffler
PURPOSE: The purpose of the study was to evaluate the characteristics of sebaceous gland carcinoma (SGC) of the ocular adnexae, which is due to a high variability in clinical, histological and immunohistochemical characteristics often challenging to diagnose. METHODS: Records of six patients with SGC were reviewed, who underwent surgical excision and who were histologically diagnosed with SGC. For comparison, there were specimens from four patients with basal cell carcinoma (BCC) and four patients with squamous cell carcinoma (SCC)...
July 24, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28711991/one-year-efficacy-of-adjunctive-use-of-ripasudil-a-rho-kinase-inhibitor-in-patients-with-glaucoma-inadequately-controlled-with-maximum-medical-therapy
#17
Hiroshi Inazaki, Satoshi Kobayashi, Yoko Anzai, Hisayoshi Satoh, Shimpei Sato, Maiko Inoue, Shin Yamane, Kazuaki Kadonosono
PURPOSE: The aim of this study was to evaluate the one-year efficacy, ability to lower intraocular pressure, and tolerability of ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy. METHODS: This prospective, non-comparative, interventional case-series study included 39 patients with primary open-angle glaucoma inadequately controlled with maximum medical therapy before treatment with ripasudil. Ripasudil was administered twice per day as adjunctive therapy to ongoing glaucoma treatment...
July 15, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28648963/the-association-between-diabetes-level-of-glycaemic-control-and-eye-infection-cohort-database-study
#18
Abdus Samad Ansari, Simon de Lusignan, William Hinton, Neil Munro, Andrew McGovern
AIM: To examine whether diabetes and the degree of glycaemic control is associated with an increased risk of acute eye infection, and prescribing of ocular antimicrobial agents. DESIGN AND SETTING: A retrospective cohort study was carried out using the Royal College of General Practitioners Research and Surveillance Centre database (RCGP RSC), a large primary care database in the United Kingdom. We compared ocular infection rates in people aged ≥15 years without diabetes to those with diabetes, both type 1 and type 2...
June 22, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28643716/prevalence-of-ocular-morbidity-in-school-going-children-in-west-uttar-pradesh
#19
Veer Singh, K P S Malik, V K Malik, Kirti Jain
AIM OF THE STUDY: This study aims to evaluate the prevalence and to make a comparison between the ocular morbidity pattern in school going children of urban and rural areas of West Uttar Pradesh. MATERIALS AND METHODS: A school-based cross-sectional study design was adopted to examine children aged 5-15 years in randomly selected urban and rural schools of West Uttar Pradesh from June 2012 to August 2014. An optometrist did the vision and refraction, and a detailed ophthalmic examination was done by an ophthalmologist...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28643231/demodex-blepharitis-treated-with-a-novel-dilute-povidone-iodine-and-dmso-system-a-case-report
#20
Jesse S Pelletier, Kara Capriotti, Kevin S Stewart, Joseph A Capriotti
INTRODUCTION: Povidone-iodine aqueous solution is an antiseptic commonly used in ophthalmology for treatment of the ocular surface. Dimethylsulfoxide (DMSO) is a well-known skin penetration enhancer that is scarcely utilized in ophthalmic drug formulations. We describe here a low-dose formulation of 0.25% PVP-I in a gel containing DMSO for the treatment of Demodex blepharitis. CASE REPORT: A 95-year-old female presented with chronic blepharitis involving both the anterior and posterior eyelid margins...
June 22, 2017: Ophthalmology and Therapy
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