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https://www.readbyqxmd.com/read/29780020/a-rare-case-of-blebharitis-phthiriasis-palpebrarum
#1
Fatma Altınsoy, Oktay Alver, Selim Doğanay
A six-year-old male patient was admitted to our hospital due to itching and scalding crusts that persisted 10-15 days in both eyes. Upon biomicroscopic examination, 5-6 semi-translucent, yellowish brown living lice attached to the upper eyelashes and a large number of eggs were observed. Following application of pilocarpine hydrochloride (Pilomann 2%, Bausch-Lomb) and topical proparacaine hydrochloride (Alcaine 0.5%, Alcon), the paralyzed parasites and eggs were manually removed by pulling with forceps. The lice were identified as adult forms of pubic louse, Pthirus pubis, and its eggs...
March 2018: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29773434/tinea-blepharo-ciliaris-in-a-13-year-old-girl-caused-by-trichophyton-benhamiae
#2
Fang-Ying Wang, Pei-Lun Sun
Tinea blepharo-ciliaris is a rare form of dermatophyte infection which involves eyelids and associated eyelashes. We report a 13-year-old girl with type I diabetes mellitus who had right eyelid swelling and eyelash loss for two weeks. The lesions were presented as erythematous patches with scales and tiny pustules on the right upper and lower eyelids with broken eyelashes. Two additional annular erythematous patches with scaly active borders were found on her right forearm and right thigh. Microscopic examination of broken eyelashes demonstrated many chains of arthroconidia and hyaline hyphae in an endothrix invasion pattern...
May 14, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29764576/-nipbl-gene-mutations-in-two-children-with-cornelia-de-lange-syndrome
#3
Yun-Jing Zhao, Hong-Wei Ma
Both children (one boy and one girl) experienced disease onset in infancy and visited the hospital due to growth retardation. They had unusual facies including thick hair, arched and confluent eyebrows, long and curly eyelashes, short nose, and micrognathia. Patient 1 had congenital heart disease (atrial septal defect and pulmonary stenosis) and special dermatoglyph (a single palmar crease). Patient 2 had cleft palate and moderate-to-severe deafness. Clinical features suggested Cornelia de Lange syndrome in both children...
May 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29757849/ocular-surface-findings-in-patients-with-lichen-planopilaris
#4
Mehdi Gheisari, Sahar Dadkhahfar, Kaveh Fadakar, Reza Mahmoud Robati, Hamideh Moravvej, Mohammad Soleimani, Reza Mirshahi
PURPOSE: Lichen planopilaris (LPP) is a chronic lymphocytic- mediated disorder that selectively involves hair follicles, leading to cicatricial alopecia. The eyelash follicle and meibomian gland (MG) might also be involved in the disease process leading to ocular surface problems. METHODS: In this Cross-sectional case -control study, twenty-three patients with histologically confirmed LPP and 23 healthy controls were recruited in this controlled study. To quantify the signs and symptoms of LPP, we used the Lichen Planopilaris Activity Index...
May 10, 2018: Cornea
https://www.readbyqxmd.com/read/29713140/better-detection-of-demodex-mites-by-l%C3%A3-ffler-s-alkaline-methylene-blue-staining-in-patients-with-blepharitis
#5
Katsuji Kiuchi
Purpose: To determine whether the Löffler's alkaline methylene blue staining method is better than no staining in detecting Demodex mites in the eyelashes of patients with blepharitis. Materials and methods: Eyelashes were collected from 22 patients with blepharitis. The mean age of the patients was 82.5±6.2 years (± SD) with a range from 71 to 93 years. Eyelashes were epilated by forceps and placed individually on microscope slides. The number of Demodex mites was determined by conventional optical microscopy before and immediately after the addition of the methylene blue staining solution...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29707390/comparison-of-efficacy-and-ocular-surface-disease-index-score-between-bimatoprost-latanoprost-travoprost-and-tafluprost-in-glaucoma-patients
#6
Wissam Georges El Hajj Moussa, Rebecca Georges Farhat, Joseph Claud Nehme, Marwan Antoun Sahyoun, Alexandre Raymond Schakal, Alexandre Edmond Jalkh, Mariana Pierre Abi Karam, Georges Georges Azar
Aim: The purpose of this study is to evaluate and compare the efficacy of 4 prostaglandin analogues (PGAs) and to determine the incidence of ocular surface disease in newly diagnosed, primary open-angle glaucoma (POAG) patients started on one of those 4 PGAs: bimatoprost (benzalkonium chloride, BAK, 0.3 mg/mL), latanoprost (BAK 0.2 mg/mL), travoprost (polyquad), and tafluprost (BAK-free). Patients and Methods: In this single-center, open-label trial, 32 patients newly diagnosed with POAG were randomly started on one of the four PGAs...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29688838/intense-pulsed-light-applied-directly-on-eyelids-combined-with-meibomian-gland-expression-to-treat-meibomian-gland-dysfunction
#7
Bei Rong, Yun Tang, Ping Tu, Ruixing Liu, Jing Qiao, Wenjing Song, Rolando Toyos, Xiaoming Yan
OBJECTIVE: To determine the efficacy and safety of intense pulsed light (IPL) applied directly on the eyelids and meibomian gland expression (MGX) in treating meibomian gland dysfunction (MGD). BACKGROUND: IPL application on the periocular skin effectively improves meibomian gland secretion and tear film break-up time (TBUT) in patients with MGD/dry eye. METHODS: This prospective, randomized, double-masked, controlled study involved 44 patients...
April 24, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29686106/embryonic-regeneration-by-relocalization-of-the-spemann-organizer-during-twinning-in-xenopus
#8
Yuki Moriyama, Edward M De Robertis
The formation of identical twins from a single egg has fascinated developmental biologists for a very long time. Previous work had shown that Xenopus blastulae bisected along the dorsal-ventral (D-V) midline (i.e., the sagittal plane) could generate twins but at very low frequencies. Here, we have improved this method by using an eyelash knife and changing saline solutions, reaching frequencies of twinning of 50% or more. This allowed mechanistic analysis of the twinning process. We unexpectedly observed that the epidermis of the resulting twins was asymmetrically pigmented at the tailbud stage of regenerating tadpoles...
April 23, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29675643/eyelash-length-for-the-diagnosis-of-atopic-dermatitis-and-ichthyosis-vulgaris-in-children-a-case-control-study
#9
Mehak Singh, Manoj Pawar
Eyelash trichomegaly (ET) is increased length (≥ 12 mm), curling, pigmentation, or thickness of eyelashes. Among acquired causes, allergic diseases and atopic dermatitis (AD) have been found to be associated with eyelash trichomegaly especially in children; however, to date, this claim has not been studied in detail. To compare the eyelash lengths of AD and ichthyosis vulgaris (IV) patients with those of age- and sex-matched patients with unrelated skin disorders, we measured (with a digital Vernier caliper) and compared the eyelash lengths of AD (n = 58) and IV (n = 31) patients to those of age- and sex-matched patients with unrelated skin disorders (n = 178)...
April 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29659435/frontalis-muscle-flap-versus-maximal-anterior-levator-resection-as-first-option-for-patients-with-severe-congenital-ptosis
#10
Ramón Medel, Salvador Molina, Luz Maria Vasquez, Josep Visa, Ana Wert, Charlotte Wolley-Dod
PURPOSE: To compare 2 surgical techniques (frontalis flap versus maximal anterior levator resection) as first surgical options for the treatment of congenital ptosis with poor levator function in patients younger than 2 years of age with a follow up of 10 years. METHODS: A retrospective study of 58 patients (71 eyelids) with severe ptosis and poor levator function who underwent frontalis muscle flap (FMF = 47) or maximal anterior levator resection (ALR = 24) for correction of their ptosis...
April 12, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29643778/-phthirus-pubis-infestation-of-the-eyelids-presenting-as-chronic-blepharoconjunctivitis-in-a-6-year-old-girl-a-case-report
#11
Viola Andin Dohvoma, Steve Robert Ebana Mvogo, Paul Jean Adrien Atangana, Pamela Nyasse, Emilienne Epee, Côme Ebana Mvogo
Purpose: To report the case of Phthirus pubis infestation of the eyelashes presenting as chronic blepharoconjunctivitis. Case Report: A 6-year-old girl presented with a 2-month history of blepharoconjunctivitis unresponsive to topical antibiotics in the left eye. Slit-lamp examination revealed the presence of nits and adult parasites on the eyelashes. Parasitological examination confirmed adult forms and nits of Phthirus pubis . There was no evidence of infestation elsewhere...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29593809/the-impact-of-age-sex-blepharitis-rosacea-and-rheumatoid-arthritis-on-demodex-mite-infection
#12
Aleksandra Sędzikowska, Maciej Osęka, Piotr Skopiński
Introduction: Two human-specific Demodex species have been described: Demodex folliculorum and Demodex brevis . A medical condition caused by the presence of Demodex is called demodicosis. Material and methods: The study material comprised eyelashes collected from 1499 patients. Results: Demodex sp. infection was revealed in 47% of patients (487 women and 216 men). We determined the following rates of infection by age groups: 1-25 (8% of infected subjects), 26-40 (36%), 41-55 (50%), 56-70 (67%), over 70 (77%)...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29546862/clinical-characteristics-and-comorbidity-of-pediatric-trichotillomania-the-study-of-38-cases-in-croatia
#13
Aleksandra Klobučar, Vera Folnegović-Šmalc, Dubravka Kocijan-Hercigonja, Slavica Sović, Ljiljana Gulić
BACKGROUND: The main goal of this study was to analyse and show clinical characteristics and psychiatric comorbidity in 38 participants aged between 10 and 17 with DSM-IV diagnoses of Trichotillomania (TTM) that we were treating at Children's Hospital Zagreb from 2008 to 2017. SUBJECTS AND METHODS: We analyzed the data obtained from semi-structured interviews by the criteria of DSM-IV, Youth Self Report (YSR) (Achenbach & Rescorla 2001) and survey that we created...
March 2018: Psychiatria Danubina
https://www.readbyqxmd.com/read/29503529/therapeutic-potential-of-bimatoprost-for-the-treatment-of-eyebrow-hypotrichosis
#14
REVIEW
Nongsak Chanasumon, Tueboon Sriphojanart, Poonkiat Suchonwanit
Eyebrows serve as a key feature of the face and have many roles, including cosmetic appearance and social communication. Eyebrow hypotrichosis, which refers to reduction or absence of the eyebrow hair, could be a major problem that leads to negative functional, psychological, and social consequences. Bimatoprost is an ophthalmic prostamide analog that is approved by the United States Food and Drug Administration for the treatment of eyelash hypotrichosis. Its proposed mechanism is stimulation of the prostaglandin receptor in dermal papilla and melanocyte, thus leading to a prolonged anagen phase and increased melanogenesis...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29489680/miller-fisher-syndrome-complicated-by-bickerstaff-brainstem-encephalitis-a-case-report
#15
Chaoyang Jing, Zhuo Wang, Chaojia Chu, Ming Dong, Weihong Lin
RATIONALE: Bickerstaff brainstem encephalitis (BBE) and Miller-Fisher syndrome (MFS) might be a pedigree disease. Herein, we report a rare case that fits the diagnoses of both MFS and BBE. PATIENT CONCERNS: A 48-year-old woman was hospitalized due to blurred vision and unsteady gait lasting for 9 days, and numbness of the limbs lasting for 6 days. Physical examination showed restricted eye movement without nystagmus, bilateral flattening of forehead and nasolabial folds, and positive eyelash sign...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29481350/surgeon-personal-protection-an-underappreciated-benefit-of-positive-pressure-exhaust-suits
#16
Justin L Makovicka, Joshua S Bingham, Karan A Patel, Simon W Young, Christopher P Beauchamp, Mark J Spangehl
BACKGROUND: Positive-pressure exhaust suits cost more than standard surgical gowns, and recent evidence suggests that they do not decrease infection risk. As a result, some hospitals and surgeons have abandoned positive-pressure exhaust suits in favor of less expensive alternatives. We propose that in addition to their original purpose of decreasing infection rates, positive-pressure exhaust suits may also improve personal protection for the surgeon and assistants, perhaps justifying their added costs...
February 23, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29475902/-in-vivo-analysis-of-prostaglandins-induced-ocular-surface-and-periocular-adnexa-modifications-in-patients-with-glaucoma
#17
REVIEW
Silvio DI Staso, Luca Agnifili, Sara Cecannecchia, Angela DI Gregorio, Marco Ciancaglini
BACKGROUND/AIM: Prostaglandin analogues (PGAs) are a first-line medical treatment for glaucoma because of their powerful intraocular pressure (IOP) lowering effect, few systemic side-effects (SEs), and the once daily administration. Despite the high systemic safety profile, the chronic use of PGAs may induce periocular and ocular surface (OS)-related side effects, which affect a significant proportion of glaucomatous patients. In this review, we summarize the current knowledge about SEs of PGAs on periocular structures and OS, and their implications in clinical practice...
March 2018: In Vivo
https://www.readbyqxmd.com/read/29462647/novel-pathogenic-recql4-variants-in-chinese-patients-with-rothmund-thomson-syndrome
#18
Baoheng Gui, Yanning Song, Xuyun Hu, Hongdou Li, Zailong Qin, Jiasun Su, Chuan Li, Xin Fan, Mengting Li, Jingsi Luo, Ying Feng, Liping Song, Shaoke Chen, Chunxiu Gong, Yiping Shen
BACKGROUND: Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder mainly characterized by cutaneous poikiloderma, sparse hair, short stature and skeletal defects. Deleterious mutations in the RecQ-like DNA helicase type 4 (RECQL4) gene have been detected in approximately two-thirds of RTS cases. METHODS: Three Chinese patients from two unrelated families were enrolled for clinical evaluation. Targeted next-generation sequencing (NGS) using a custom panel consisting of 705 short-stature-related genes was performed for the probands...
May 15, 2018: Gene
https://www.readbyqxmd.com/read/29440861/eyelashes-trichomegaly-an-unusual-side-effect-of-gefitinib-therapy
#19
Chaturbhuj R Agrawal, Pankaj Goyal, Dinesh Chandra Doval, Kumardeep Dutta, Kshitij Domadia, Silky Kothiwal
Evolution of targeted therapy has changed the spectrum of treatment in oncology since the past two decades as lots of newer agents are being added to the pharmacologic armamentarium of cancer therapy. Epidermal growth factor receptor inhibitors form one such advancing field with many newer agents being investigated and they are used in wide variety of malignancies such as head and neck cancer, lung cancer, and even gastrointestinal malignancies such as pancreatic cancer. Various troublesome side effects of these agents include diarrhea, severe fatigability, severe skin rashes, and deranged liver function tests which may require treatment interruption or dose reduction resulting in decreased response to treatment...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29426737/-demodex-genus-colonizing-parasites-of-healthy-people-or-mites-associated-with-ocular-pathology
#20
Florencia Mongi, Laura Laconte, Rodolfo D Casero
Demodex folliculorum and Demodex brevis are mites that are responsible for human demodicosis affecting skin and frequently linked to ocular diseasess. The aim of this work was to determine the association between Demodex sp. and eyelid and eyelash diseases and to establish the predisposing factors for acquiring this parasitic disease. Eyelashes from symptomatic and asymptomatic patients (n=72) between 9 and 82 years old were analyzed, where 53% were positive for Demodex sp., of which 66% manifested ocular symptoms and pathologies, blepharitis and dry eye being prevalent...
February 6, 2018: Revista Argentina de Microbiología
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