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Fulvia Gloria-Bottini, Maria Ammendola, Patrizia Saccucci, Adalgisa Pietropolli, Anna Neri, Andrea Magrini, Egidio Bottini
BACKGROUND: The possible association between allergy and neoplastic disorders has been the subject of many investigations but no general relationship has been determined. Little attention, however, has been paid to the possible role of allergy in the clinical manifestations of these diseases. In this study, the role of allergy in the susceptibility to uterine leiomyomas and in their growth was investigated. Interaction with ACP1 , a genetic polymorphism associated with the growth of leiomyomas, has been also considered...
October 2015: Journal of Reproduction & Infertility
M Cirstoiu, O Munteanu, O Bodean, C Cirstoiu
The spondylocostal dysostosis (SCD) is one of the two major clinico-radiological subtypes of the Jarcho-Levin syndrome (JLS). The JLS is a rare heterogeneous entity characterized by facial dysmorphism, short-neck, short-trunk, normal sizes limbs, with multiple vertebral anomalies at all levels of the vertebral column and costal defects. The JLS has been classified into 2 major clinical phenotypes, based on the extent and distribution of skeletal anomalies, the pattern of inheritance and the prognosis. We report the case of a non-consanguineous 35-year-old female patient, with a history of multiple large leiomyomas gravida 1, para 1...
March 15, 2013: Journal of Medicine and Life
Emanuele Cigna, Michele Maruccia, Antonietta Troccola, Pasquale Fino, Valentina Sorvillo, Nicolò Scuderi
INTRODUCTION: Vascular leiomyoma is a rare tumour of smooth muscle origin. It has been reported in many anatomical sites, but it usually affects limbs. It's recurrence rate is slow but it's quite difficult to make diagnosis. CASE REPORT: The study describes the case of a 53-year-old man, with a subcutaneous, large vascular leiomyoma of the right clavicular region. The patient had a painful, slow-growing mass, measuring more than 20 mm. The mass had a relatively homogeneous, hypoechoic-echo texture, with a small amount of posterior acoustic enhancement...
November 2010: Annali Italiani di Chirurgia
Cláudio Emílio Bonduki, Gilmar de Oliveira Dornelas Junior, André Bernardo, Manuel de Jesus Simões, Rodrigo de Aquino Castro, Mariano Tamura Vieira Gomes, Manoel João Batista Castello Girão
PURPOSE: To analyze histomorphometric consequences of the uterine arteries embolization (UAE) in the uterine tissue, especially by collagen tissue quantification through uterine biopsy, before and after treatment of uterine leiomyoma. METHODS: 15 patients with symptomatic leyomioma and/or infertility, submitted to UAE, participated in the study according to the study exclusion criteria, after having signed an informed consent. Uterine biopsy was performed in the secretory phase of the menstrual cycle, before and three months after the procedure, to evaluate the collagen...
December 2009: Revista Brasileira de Ginecologia e Obstetrícia
Antonio Nocchi Kalil, Marcelo Tonding Ferreira, Fernando Ressler, Cláudio Zettler
Diagnosis and treatment of hepatic tumors are a challenge for the surgeon in some situations. There are many histologic types of these neoplasms, and their diagnoses are increasing. Leyomioma of the liver is a rare pathology that is presented in this article in a 44 years old woman without immunosuppression. A review about its clinical aspects, image diagnosis and surgical therapy is discussed, based on the world medical literature.
August 2009: Revista do Colégio Brasileiro de Cirurgiões
Vítor Sousa, Lina Carvalho
Glomic tumours are perivascular tumours whose cells resemble modified smooth muscular cells of the glomic body. They are more frequent in the subungueal region and rare in the lung. The authors present a case of a 62 year old women with left thoracic pain and great enforces dyspnoea. She presented a solitary nodule in the external basal segment of the LLL, 1.9 cm diameter, circumscribed, firm and with nodular whitish rose cut surface. Glomic tumours are generally benign. They may origin in ectopic glomic cells or be differentiated from non glomic cells...
May 2006: Revista Portuguesa de Pneumologia
M Purrello, C Di Pietro, A Rapisarda, V Amico, V Giunta, H Engel, S Stevens, Y Hsieh, M Teichman, Z Wang, G Sichel, R Roeder, K H Grzeschik
TFIIIB, TFIIIC2, and PTF/SNAPC are heteromultimeric general transcription factors (GTFs) needed for expression of genes encoding small cytoplasmic (scRNAs) and small nuclear RNAs (snRNAs). Their activity is stimulated by viral oncogenes, such as SV40 large T antigen and Adenovirus E1A, and is repressed by specific transcription factors (STFs) acting as anti-oncogenes, such as p53 and pRb. GTFs role as final targets of critical signal transduction pathways, that control cell proliferation and differentiation, and their involvement in gene expression regulation suggest that the genes encoding them are potential proto-oncogenes or anti-oncogenes or may be otherwise involved in the pathogenesis of inherited genetic diseases...
August 9, 2001: Oncogene
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