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risk factor of periodontitis

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https://www.readbyqxmd.com/read/28534880/a-tale-of-two-risks-smoking-diabetes-and-the-subgingival-microbiome
#1
Sukirth M Ganesan, Vinayak Joshi, Megan Fellows, Shareef M Dabdoub, Haikady N Nagaraja, Benjamin O'Donnell, Neeta Rohit Deshpande, Purnima S Kumar
Although smoking and diabetes have been established as the only two risk factors for periodontitis, their individual and synergistic impacts on the periodontal microbiome are not well studied. The present investigation analyzed 2.7 million 16S sequences from 175 non-smoking normoglycemic individuals (controls), smokers, diabetics and diabetic smokers with periodontitis as well as periodontally healthy controls, smokers and diabetics to assess subgingival bacterial biodiversity and co-occurrence patterns. The microbial signatures of periodontally healthy smokers, but not diabetics, were highly aligned with the disease-associated microbiomes of their respective cohorts...
May 23, 2017: ISME Journal
https://www.readbyqxmd.com/read/28529526/genetic-factors-and-the-risk-of-periodontitis-development-findings-from-a-systematic-review-composed-of-13-studies-of-meta-analysis-with-71-531-participants
#2
REVIEW
Maélson Klever da Silva, Antonio Carlos Gonçalves de Carvalho, Even Herlany Pereira Alves, Felipe Rodolfo Pereira da Silva, Larissa Dos Santos Pessoa, Daniel Fernando Pereira Vasconcelos
Purpose. This work aimed to synthesize the results of recent meta-analysis focusing on polymorphism in inflammatory mediators and its relation with the risk of periodontitis development. Materials and Methods. A systematic search was conducted using databases for publications prior to October 2016. Three examiners extracted data from articles with a clear association between polymorphisms in the inflammatory mediator gene and the development of periodontitis through meta-analysis using the fixed or randomized statistical models to calculate the Odds Ratio with values of P < 0...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28515921/association-between-periodontitis-and-prognosis-of-pancreatobiliary-tract-cancer-a-pilot-study
#3
Takayuki Maruyama, Takaaki Tomofuji, Tatsuya Machida, Hironari Kato, Koichiro Tsutsumi, Daisuke Uchida, Akinobu Takaki, Toshiki Yoneda, Hisataka Miyai, Hirofumi Mizuno, Daisuke Ekuni, Hiroyuki Okada, Manabu Morita
Several studies have indicated that periodontitis is a risk factor for cancer. However, the association between periodontitis and the prognosis of pancreatobiliary tract cancer remains unclear. The aim of this pilot study was to investigate the association between periodontitis and prognosis of pancreatobiliary tract cancer. A total of 22 patients diagnosed with pancreatobiliary tract cancer were analyzed. Oral health status, including severity of periodontitis, general health status and biochemical serum markers were evaluated...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28513519/attitude-and-knowledge-of-family-medicine-practitioners-towards-the-association-between-periodontal-disease-and-obesity
#4
Z Akram, T Abduljabbar, A Hanif, A Khan, F Vohra
OBJECTIVES: To assess the attitude and knowledge of family medicine practitioners (FMPs) towards the association between periodontal disease and obesity. MATERIALS AND METHODS: A cross-sectional study was performed and a 13-item survey questionnaire was given to FMPs practicing in 12 different teaching hospitals in Karachi, Pakistan. The questions were aimed at exploring the knowledge of FMP's regarding the association of obesity and periodontal disease and their attitude towards the association of obesity and periodontal disease...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28513509/relationship-between-alexithymia-and-chronic-periodontitis
#5
U Sezer, K Üstün, S Z Şenyurt, K Altınbaş, K Erciyas
OBJECTIVE: The aim of this study was to investigate the potential relationship between alexithymia and chronic periodontitis. MATERIALS AND METHODS: A case-control study of 222 male and female subjects aged 21-63 years was conducted. The participants were divided into a chronic periodontitis group (n = 114) and a control group (n = 108) with no history of periodontitis. The Toronto Alexithymia Scale (TAS-20) was used to evaluate alexithymia status of the subjects...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28511516/to-evaluate-and-compare-periodontal-disease-and-smoking-as-a-parallel-risk-factor-for-systemic-health-by-gauging-the-serum-c-reactive-protein-levels
#6
Ruchi Dinesh Raval, Payal Sharma, Sarath Chandran, Dharmesh Vasavada, Priyadarshini Nadig, Gaurav Bakutra
INTRODUCTION: Physiologic and metabolic changes that occur immediately after a damage or disease are known as Acute Phase Reaction (APR). Acute Phase Proteins (APP) are blood proteins secreted by hepatocytes during APR C-Reactive Protein (CRP) being the important one. AIM: Present study was designed to estimate and compare the levels of the serum CRP in current smokers, former smokers and non-smokers, with and without periodontitis. MATERIALS AND METHODS: An experimental study was planned on 165 subjects who were divided into four groups...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28497901/risk-factors-of-periodontal-disease-in-vietnamese-patients
#7
Thuy A V Pham, Thoai Q Kieu, Lan T Q Ngo
AIM: The aim of the present study was to assess the association of periodontitis with dental and smoking behaviors, self-perception of oral status, dental knowledge, and obesity in Vietnamese patients. METHODS: A cross-sectional study was conducted on 367 adults who first visited the Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Information on demographic characteristics, dental and smoking behaviors, self-perception of oral status, dental knowledge, and nutritional status was investigated by a self-administered questionnaire...
May 12, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28496317/is-periodontitis-a-comorbidity-of-copd-or-can-associations-be-explained-by-shared-risk-factors-behaviors
#8
REVIEW
Stephanie Hobbins, Iain Lc Chapple, Elizabeth Sapey, Robert A Stockley
COPD is recognized as having a series of comorbidities potentially related to common inflammatory processes. Periodontitis is one of the most common human inflammatory diseases and has previously been associated with COPD in numerous observational studies. As periodontitis and COPD are both chronic, progressive conditions characterized by neutrophilic inflammation with subsequent proteolytic destruction of connective tissue, it has been proposed that they share common pathophysiological processes. The mechanisms proposed to link COPD and periodontitis include mechanical aspiration of oral contents into the respiratory tree, overspill of locally produced inflammatory mediators into the systemic circulation or oral or lung-derived bacteremia activating an acute-phase response and also reactive oxygen species (ROS) and cytokine release by systemic neutrophils at distant sites...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28495409/effect-of-asymptomatic-visible-third-molars-on-periodontal-health-of-adjacent-second-molars-a-cross-sectional-study
#9
Hong-Lei Qu, Bei-Min Tian, Kun Li, Li-Na Zhou, Zhi-Bang Li, Fa-Ming Chen
PURPOSE: Evidence that asymptomatic third molars (M3s) negatively affect their adjacent second molars (A-M2s) is limited. The present study evaluated the association between visible M3s (V-M3s) of various clinical status with the periodontal pathologic features of their A-M2s. PATIENTS AND METHODS: Subjects with at least 1 quadrant having intact first and second molars, either with V-M3s and symptom free or without adjacent V-M3s, were enrolled in the present cross-sectional investigation...
April 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28492747/common-operative-procedural-errors-and-clinical-factors-associated-with-root-canal-treatment
#10
Carlos Estrela, Jesus Djalma Pécora, Cyntia R A Estrela, Orlando A Guedes, Brunno S F Silva, Carlos José Soares, Manoel Damião Sousa-Neto
Operative procedural errors must be well analyzed in order to avoid influence negatively the root canal treatment (RCT) prognosis. The successful RCT prevents tooth loss and avoids pain and apical periodontitis. This review aimed to categorize common operative procedure errors and clinical factors associated with RCT. Based on this, will be approached common errors of procedures within the clinical operative sequence: endodontic treatment planning, pulp and periapical disease diagnosis, anaesthesia, access cavity preparation, isolation with rubber dam, root canal preparation, root canal filling and retreatment, restoration of endodontically treated teeth, postoperative pain, follow up of endodontically treated teeth...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28492360/resveratrol-inhibits-periodontitis-related-bone-loss-in-rats-submitted-to-cigarette-smoke-inhalation
#11
Fernanda V Ribeiro, Danilo S Pino, Felipe C Franck, Bruno B Benatti, Howard Tenenbaum, Dip Perio, John E Davies, Suzana P Pimentel, Renato C Casarin, Fabiano R Cirano, Marcio Z Casati
BACKGROUND: Alternative therapeutic approaches have been explored in order to modulate the host's response to periodontal disease. The knowledge of new strategies to treat periodontitis is particularly relevant in patients presenting augmented risk to periodontitis, as smokers. The aim of this study was to investigate the impact of Resveratrol (RESV) on the progression of experimental periodontitis (EP) in the presence of cigarette smoke inhalation (CSI). METHODS: Rats were assigned to: CSI+RESV(n=20); CSI+placebo(n=20); Non-CSI(n=20)...
May 11, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28483226/pediatric-sialolithiasis-is-not-related-to-oral-or-oropharyngeal-infection-a-population-based-case-control-study-using-the-korean-national-health-insurance-database
#12
Seong Jun Won, Eunkyu Lee, Hee Jung Kim, Hyun-Kyung Oh, Han-Sin Jeong
OBJECTIVES: Poor oral hygiene is one of the risk factors for sialolithiasis particularly in adults; however the etiology of sialolithiasis in pediatric patients remains largely unknown. The purpose of this study is to identify the association between sialolithiasis and the oral/oropharyngeal infections in the pediatric population, as surrogate indicators for oral hygiene and retrograde infections to the affected salivary gland. METHODS: This was a population based case-control study using the Korean National Health Insurance Database...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28467728/the-pf4-ppbp-cxcl5-gene-cluster-is-associated-with-periodontitis
#13
A Shusterman, M Munz, G Richter, S Jepsen, W Lieb, B Krone, P Hoffman, M Laudes, J Wellmann, K Berger, T Kocher, S Offenbacher, K Divaris, A Franke, S Schreiber, H Dommisch, E Weiss, A S Schaefer, Y Houri-Haddad, F A Iraqi
Periodontitis is a common dysbiotic inflammatory disease with an estimated heritability of 50%. Due to the limited sample size of available periodontitis cohorts and the underlying trait heterogeneity, genome-wide association studies (GWAS) of chronic periodontitis (CP) have been unsuccessful in discovering susceptibility factors. A strategy that combines agnostic GWAS with a well-powered candidate-gene approach has the potential to discover novel loci. We combined RNA-seq data from gingival tissues with quantitative trait loci (QTLs) that were identified in a F2-cross of mice resistant and susceptible to infection with oral bacterial pathogens...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28464230/patients-with-chronic-periodontitis-present-increased-risk-for-osteoporosis-a-population-based-cohort-study-in-taiwan
#14
L-P Mau, Y-C Kuan, Y-W C Tsai, J-J Lin, G Huynh-Ba, P-W Weng, Y-S Shieh, W-C Cheng, R-Y Huang
OBJECTIVES: Chronic periodontitis is a bone destructive inflammatory disease with an adverse impact on general health and suggested underlying factors in common with osteoporosis. A few studies have examined the possible relationship between chronic periodontitis and osteoporosis; however, the results remain inconclusive. This longitudinal follow-up study investigated the possible risk of patients with chronic periodontitis to present osteoporosis by using a population-based national health insurance data set in Taiwan...
May 2, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28462407/periodontal-disease-like-bone-loss-after-%C3%A2-adjuvant-radiotherapy-in-the-head-and-neck-region-%C3%A2-a-case-report-and-review-of-the-literature
#15
Florian D Güll, Herbert Deppe, Marco Kesting, Claudia Schwarzer
OBJECTIVE: The purpose of this study was to present a rare case of periodontal disease-like bone loss and possible treatment options. This paper discusses the pros and cons of conservative treatment and radical surgical intervention and summarizes possible complications. It focuses also on the individual situation of the patient and provides a review of literature. METHOD AND MATERIALS: A 32-year-old patient presented with widening of the periodontal spaces and apical translucencies at every tooth after adjuvant radiotherapy of an oral squamous cell carcinoma (OSCC) of the tongue...
April 28, 2017: Quintessence International
https://www.readbyqxmd.com/read/28462008/association-between-periodontal-flap-surgery-for-periodontitis-and-vasculogenic-erectile-dysfunction-in-koreans
#16
Jae-Hong Lee, Jung-Kyu Choi, Sang-Hyun Kim, Kyung-Hyun Cho, Young-Taek Kim, Seong-Ho Choi, Ui-Won Jung
PURPOSE: The National Health Insurance Service-National Sample Cohort and medical checkup data from 2002 to 2013 were used to evaluate the association between periodontal surgery for the treatment of periodontitis (PSTP) and vasculogenic erectile dysfunction (VED). METHODS: Bivariate and multivariate logistic regression analyses were applied to a longitudinal retrospective database to assess the association between PSTP and VED while adjusting for the potential confounding effects of sociodemographic factors (age, household income, insurance status, health status, residence area, and smoking status) and comorbidities (diabetes mellitus, angina pectoris, cerebral infarction, and myocardial infarction)...
April 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28460082/reducing-cancer-burden-in-the-population-an-overview-of-epidemiologic-evidence-to-support-policies-systems-and-environmental-changes
#17
Elizabeth A Platz
"Reducing Cancer Burden in the Population: Epidemiologic Evidence to Support Policies, Systems, and Environmental Changes" is a compilation of 11 reviews addressing aspects of primary prevention of cancer (early life factors, vitamin D, and periodontal disease and the oral microbiome); primary and secondary prevention (in the transgender population); surveillance following secondary prevention (personalizing follow-up of patients diagnosed with an adenoma based on colorectal cancer risk); tertiary prevention (physical activity as an adjuvant to cancer treatment, measurement of patient-reported physical functioning in cancer treatment trials, and implementation of palliative care recommendations); and all 3 (changing epidemiology of oral cancers)...
January 1, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28456557/no-post-no-core-approach-to-restore-severely-damaged-posterior-teeth-an-up-to-10-year-retrospective-study-of-documented-endocrown-cases
#18
Marcia M Belleflamme, Sabine O Geerts, Marie M Louwette, Charlotte F Grenade, Alain J Vanheusden, Amélie K Mainjot
OBJECTIVES: The objectives of the present study were to (1) retrospectively evaluate documented cases of ceramic and composite endocrowns performed using immediate dentin sealing (IDS); (2) correlate failures with clinical parameters such as tooth preparation characteristics and occlusal parameters. METHODS: 99 documented cases of endocrowns were evaluated after a mean observation period of 44.7±34.6months. A classification of restorations was established in function of the level of damage of residual tooth tissues after preparation, from 1 to 3...
April 27, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28453689/periodontal-disease-edentulism-and-pancreatic-cancer-a-meta-analysis
#19
P Maisonneuve, S Amar, A B Lowenfels
Background: Periodontal disease (PD), now our commonest infectious disorder leads to tooth loss, and has been linked to various systemic diseases, including various types of cancer. The aim of this study is to provide a systematic review and a meta-analysis of the relationship between PD, edentulism, and pancreatic cancer (PC). Patients and methods: From an initial review of 327 references we selected eight studies concerning periodontitis or edentulism with sufficient quantitative information to allow us to examine the risk of PC...
May 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28453484/can-better-management-of-periodontal-disease-delay-the-onset-and-progression-of-alzheimer-s-disease
#20
Alice Harding, Sarita Robinson, StJohn Crean, Sim K Singhrao
A risk factor relationship exists between periodontal disease and Alzheimer's disease (AD) via tooth loss, and improved memory following dental intervention. This links the microbial contribution from indigenous oral periodontal pathogens to the manifestation of chronic conditions, such as AD. Here, we use Porphyromonas gingivalis infection to illustrate its effect on mental health. P. gingivalis infection, in its primary sub-gingival niche, can cause polymicrobial synergy and dysbiosis. Dysbiosis describes the residency of select commensals from the oral cavity following co-aggregation around the dominant keystone pathogen, such as P...
2017: Journal of Alzheimer's Disease: JAD
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