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https://www.readbyqxmd.com/read/29142443/oral-health-and-erectile-dysfunction
#1
REVIEW
Vijendra P Singh, Sunil K Nettemu, Sowmya Nettem, Rajesh Hosadurga, Sangeeta U Nayak
Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29138754/the-relation-between-periodontopathogenic-bacterial-levels-and-resistin-in-the-saliva-of-obese-type-2-diabetic-patients
#2
Natheer Al-Rawi, Farah Al-Marzooq
This study aims to investigate the relation between resistin and periodontopathogenic bacterial levels in the saliva of obese adults compared to healthy control and to examine whether salivary resistin can serve as a biomarker of type 2 diabetes in obese patients. A total of 78 saliva samples were collected from patients attending to the University Dental Hospital, Sharjah, UAE. The patients were divided into three equal groups: obese diabetics, obese nondiabetics, and nonobese nondiabetic control. Salivary resistin was measured using ELISA...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29132069/risk-factors-for-tooth-loss-in-middle-and-older-age-after-up-to-10-years-an-observational-cohort-study
#3
Alexander Jochen Hassel, Volkan Safaltin, Sabine Grill, Johannes Schröder, Hans-Werner Wahl, Anna-Luisa Klotz, Edriss Habibi, Peter Rammelsberg, Andreas Zenthöfer
OBJECTIVE: The objective of this research was to identify risk factors for tooth loss in two birth cohorts, quinquagenarians and septuagenarians, after up to 10 years of clinical observation. DESIGN: One hundred and twenty-three participants were recruited from the Interdisciplinary Study of Adult Development (ILSE) and examined at baseline and up to 10 years after. Thirty-nine and 84 participants belonged to the older (OC; born in 1930/32) cohort and younger (YC; born in 1950/52) cohort, respectively...
November 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29131099/the-prevalence-of-periodontitis-is-increased-in-psoriasis-and-linked-to-its-inverse-subtype
#4
Clemens Painsi, Alexander Hirtenfelder, Bernhard Lange-Asschenfeldt, Franz Quehenberger, Peter Wolf
Periodontitis and psoriasis are suggested to be co-occurring, chronic inflammatory conditions with overlapping characteristics. However, respective evidence is rare and data on risk factors of periodontitis in psoriasis patients are minimal. The aim of this study was to expand the evidence of psoriasis-associated periodontitis and establish a potential risk profile for periodontitis. In total, data from 209 exacerbated psoriasis patients were retrospectively analyzed on recordings of periodontitis and compared with those of 91 patients with chronic spontaneous urticaria (CSU)...
November 2, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/29129846/the-il18-promoter-polymorphism-rs1946518-is-associated-with-the-risk-of-periodontitis-in-japanese-women-the-kyushu-okinawa-maternal-and-child-health-study
#5
Keiko Tanaka, Yoshihiro Miyake, Takashi Hanioka, Shinya Furukawa, Nobuyuki Miyatake, Masashi Arakawa
Interleukin-18 (IL-18) is a proinflammatory cytokine that plays an important role in periodontitis and its polymorphisms might modulate the individual susceptibility to periodontitis. Only a limited number of studies on the association between IL18 single-nucleotide polymorphisms (SNPs) and the risk of periodontitis have been realized, however. The aim of this case-control study among young post-partum Japanese women (18 to 45 years) was to determine the impact of SNPs, rs1946518 (-607 C/A) and rs187238 (-137G/C), on periodontitis...
2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29122069/potential-risk-for-localized-aggressive-periodontitis-in-african-american-preadolescent-children
#6
Noel K Childers, Hernan Grenett, Casey Morrow, Ranjit Kumar, Peter A Jezewski
PURPOSE: This study aimed to evaluate the potential risk for localized aggressive periodontitis (LAgP) in African American children by detection of the potential periodontal pathogen Aggregatibacter actinomycetemcomitans (Aa) using polymerase chain reaction (PCR) and microbiome analysis. METHODS: Twenty-one pre-adolescents (age range equals 10.7 to 13.1 years old) were recruited, for this IRB-approved study. Oral examination included limited periodontal examination determining bleeding index (BOP) and periodontal probing (PD)...
July 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29114946/reported-gum-disease-as-a-cardiovascular-risk-factor-in-adults-with-intellectual-disabilities
#7
K Hsieh, S Murthy, T Heller, J H Rimmer, G Yen
BACKGROUND: Several risk factors for cardiovascular disease (CVD) have been identified among adults with intellectual disabilities (ID). Periodontitis has been reported to increase the risk of developing a CVD in the general population. Given that individuals with ID have been reported to have a higher prevalence of poor oral health than the general population, the purpose of this study was to determine whether adults with ID with informant reported gum disease present greater reported CVD than those who do not have reported gum disease and whether gum disease can be considered a risk factor for CVD...
November 8, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29114218/periodontitis-microbiomes-and-their-role-in-alzheimer-s-disease
#8
Anna B Pritchard, StJohn Crean, Ingar Olsen, Sim K Singhrao
As far back as the eighteenth and early nineteenth centuries, microbial infections were responsible for vast numbers of deaths. The trend reversed with the introduction of antibiotics coinciding with longer life. Increased life expectancy however, accompanied the emergence of age related chronic inflammatory states including the sporadic form of Alzheimer's disease (AD). Taken together, the true challenge of retaining health into later years of life now appears to lie in delaying and/or preventing the progression of chronic inflammatory diseases, through identifying and influencing modifiable risk factors...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29112241/periodontal-therapy-for-the-management-of-cardiovascular-disease-in-patients-with-chronic-periodontitis
#9
REVIEW
Chunjie Li, Zongkai Lv, Zongdao Shi, Ye Zhu, Yafei Wu, Longjiang Li, Zipporah Iheozor-Ejiofor
BACKGROUND: There is an association between chronic periodontitis and cardiovascular disease (CVD). However, it is not known whether periodontal therapy could prevent or manage CVD in patients with chronic periodontitis. OBJECTIVES: The objective of this systematic review was to investigate the effects of periodontal therapy in preventing the occurrence of, and management or recurrence of, CVD in patients with chronic periodontitis. SEARCH METHODS: Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 31 August 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, 2017, Issue 7), MEDLINE Ovid (1946 to 31 August 2017), Embase Ovid (1980 to 31 August 2017) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL EBSCO) (1937 to 31 August 2017) ...
November 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29111278/the-association-of-inflammatory-markers-and-periodontal-indexes-with-the-risk-of-coronary-heart-disease-in-chinese-patients-with-type-2-diabetes-mellitus
#10
Ling Chen, Bin Wei, Liang Xu, Yun Wu
OBJECTIVES: The present study was designed to investigate the association of four inflammatory markers and five periodontal indexes with the risk of coronary heart disease (CHD) in 131 patients with type 2 diabetes mellitus (T2DM). METHODS: All subjects were inpatients, including 63 T2DM patients with comorbid CHD ("cases") and 68 T2DM patients without CHD ("controls"). The diagnosis of CHD is based on coronary angiography. RESULTS: Peripheral blood concentrations of high sensitivity C-reactive protein (hs-CRP) (11...
October 28, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29110146/atherosclerosis-periodontal-disease-and-treatment-with-resolvins
#11
REVIEW
James A Hamilton, Hatice Hasturk, Alpdogan Kantarci, Charles N Serhan, Thomas Van Dyke
PURPOSE OF REVIEW: This review aims to discuss the existing evidence on the link between atherosclerosis and periodontitis by particularly presenting new findings that link the pathology and therapy of these diseases. Acute vascular ischemic events that can lead to stroke or myocardial infarction are initiated by inflammatory processes leading to rupture or erosion of plaques susceptible to thrombosis ("high risk" or "vulnerable"). These are highly inflamed plaques residing in the media and adventitia that may not be detected by angiography measurments of luminal narrowing...
November 6, 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29084415/association-of-distinct-fine-specificities-of-anti-citrullinated-peptide-antibodies-with-elevated-immune-responses-to-prevotella-intermedia-in-a-subgroup-of-patients-with-rheumatoid-arthritis-and-periodontitis
#12
Anja Schwenzer, Anne-Marie Quirke, Anna M Marzeda, Alicia Wong, Anna B Montgomery, Harlan R Sayles, Sigrun Eick, Katarzyna Gawron, Maria Chomyszyn-Gajewska, Katarzyna Łazarz-Bartyzel, Simon Davis, Jan Potempa, Benedikt M Kessler, Roman Fischer, Patrick J Venables, Jeffrey B Payne, Ted R Mikuls, Kim S Midwood
OBJECTIVE: In addition to the long-established link with smoking, periodontitis (PD) is a risk factor for rheumatoid arthritis (RA). This study was undertaken to elucidate the mechanism by which PD could induce antibodies to citrullinated peptides (ACPAs), by examining the antibody response to a novel citrullinated peptide of cytokeratin 13 (CK-13) identified in gingival crevicular fluid (GCF), and comparing the response to 4 other citrullinated peptides in patients with RA who were well-characterized for PD and smoking...
October 30, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29081914/immunoglobulin-g-antibodies-against-porphyromonas-gingivalis-or-aggregatibacter-actinomycetemcomitans-in-cardiovascular-disease-and-periodontitis
#13
Christian Damgaard, Jesper Reinholdt, Christian Enevold, Nils-Erik Fiehn, Claus Henrik Nielsen, Palle Holmstrup
Objectives: The aim was to elucidate whether levels of circulating antibodies to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis correlate to loss of attachment, as a marker for periodontitis and cardiovascular disease (CVD). Design: Sera were collected from 576 participants of the Danish Health Examination Survey (DANHES). Immunoglobulin G antibodies against lipopolysaccharide (LPS) and protein antigens from the a, b and c serotypes of A. actinomycetemcomitans and P. gingivalis were quantified by titration in ELISA plates coated with a mixture of antigens prepared by disintegration of bacteria...
2017: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/29079615/%C3%AE-glucanase-activity-of-the-oral-bacterium-tannerella-forsythia-contributes-to-the-growth-of-a-partner-species-fusobacterium-nucleatum-in-co-biofilms
#14
Kiyonobu Honma, Angela Ruscitto, Ashu Sharma
Tannerella forsythia and Fusobacterium nucleatum are dental plaque bacteria implicated in the development of periodontitis. These two species have been shown to form synergistic biofilms and found to be closely associated in dental plaque biofilms. A number of genetic loci for TonB-dependent membrane receptors (TDR) for glycan acquisition, with many existing in association with genes coding for enzymes involved in the breakdown of complex glycans, have been identified in T. forsythia In this study, we focused on a locus, BFO_0186 -- BFO_0188, that codes for a predicted TDR-SusD transporter along with a putative β-glucan hydrolyzing enzyme (BFO_0186)...
October 27, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29064800/the-relationship-between-colonization-resistance-of-the-oral-cavity-and-individual-typological-characteristics-of-personality-dental-aspects
#15
Tetiana A Petrushanko, Viktoriia V Chereda, Galina A Loban'
INTRODUCTION: The present article deals with the role of the oral mucosa colonization resistance in the implementation of the influence of individual-typological characteristics of the individual susceptibility to caries and inflammatory periodontal diseases. THE AIM: to study the role of colonization resistance of the oral mucosa in the implementation of the influence of individual-typological characteristics of the individual susceptibility to caries and inflammatory periodontal diseases...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29063912/-importance-of-dental-care-to-maintain-oral-health-of-children-and-youth-with-type-1-diabetes
#16
Anna Kuźmiuk, Grażyna Marczuk-Kolada, Elżbieta Łuczaj-Cepowicz, Marta Obidzińska, Ewa Chorzewska, Urszula Wasilczuk, Anna Kierklo, Sławomir Dariusz Szajda
BACKGROUND: Dental care for children and youth with type 1 diabetes should rely on reliable examination of the oral cavity, early treatment of dental caries and maintenance of the treatment results. This can be achieved through regular control visits consistent with the standards, and also through following the recommendations for prevention of dental caries and periodontal disease. The aim of the study was to investigate whether dental care allows to preserve good oral health of children and youth with type 1 diabetes...
October 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/29061111/normative-prosthodontic-care-need-does-it-impact-the-daily-life-of-young-saudis-with-high-level-of-oral-diseases-a-cross-sectional-study
#17
Fahad Al-Harbi, Maha El Tantawi
BACKGROUND: Assessing the need for prosthodontic care previously included older age groups. There is less information about younger populations who may need this care because of high disease levels. The aim of this study was to assess the normative need for prosthodontic care in a young Saudi population with high oral disease levels, the associated factors and its impact on daily life. METHODS: A cross sectional study included Saudi adults in the Eastern Province in 2016...
October 23, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29053486/retrospective-analysis-of-sinus-membrane-thickening-profile-causal-factors-and-its-influence-on-complications
#18
Hyun-Chang Lim, Ji-Yeon Nam, Jae-Kook Cha, Jung-Seok Lee, Dong-Woon Lee, Ui-Won Jung, Seong-Ho Choi
PURPOSE: To retrospectively determine the profile of the sinus membrane (SM), potential factors affecting SM thickening (SMT), and the correlation between SMT and sinus augmentation (SA) complications. MATERIALS AND METHODS: In the patients who received lateral SA, SMT was classified in sagittal sections of cone-beam computed tomography according to its thickness and morphology. The correlation between SMT and the following factors was analyzed: age, sex, endodontic and periodontic statuses of neighboring teeth, and shape of the sinus inferior border...
October 17, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/29047351/lifestyle-factors-are-significantly-associated-with-the-locomotive-syndrome-a-cross-sectional-study
#19
Manabu Akahane, Shingo Yoshihara, Akie Maeyashiki, Yasuhito Tanaka, Tomoaki Imamura
BACKGROUND: The Japanese Orthopedic Association first proposed the concept of "locomotive syndrome" in 2007. It refers to circumstances in which elderly people need nursing care services or are at high risk of requiring such services within a short time. Recently, the public health burden of providing nursing care for elderly individuals has increased. Therefore, locomotive syndrome, and the means of preventing it, are a major public health focus in Japan. The purpose of this study was to investigate the relationships of lifestyle factors, such as smoking, alcohol consumption, sleep duration, and dental health, with locomotive syndrome...
October 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29046054/porphyromonas-gingivalis-lipopolysaccharide-stimulation-in-human-periodontal-ligament-stem-cells-role-of-epigenetic-modifications-to-the-inflammation
#20
Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
Periodontitis is a chronic oral inflammatory disease produced by bacteria. Gingival retraction and bone and connective tissues resorption are the hallmarks of this disease. Chronic periodontitis may contribute to the risk of onset or progression of neuroinflammatory pathological conditions, such as Alzheimer's disease. The main goal of the present study was to investigate if the role of epigenetic modulations is involved in periodontitis using human periodontal ligament stem cells (hPDLSCs) as an in vitro model system...
August 25, 2017: European Journal of Histochemistry: EJH
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