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https://www.readbyqxmd.com/read/29783069/association-between-the-rs1143634-polymorphism-in-interleukin-1b-and-chronic-periodontitis-results-from-a-meta-analysis-composed-by-54-case-control-studies
#1
REVIEW
Felipe Rodolfo Pereira da Silva, Any Carolina Cardoso Guimarães Vasconcelos, Luiz Felipe de Carvalho França, David Di Lenardo, Hélio Mateus Silva Nascimento, Daniel Fernando Pereira Vasconcelos
Several factors are involved in the periodontitis with host response through cytokines and as well as with influence of polymorphisms in cytokine genes, however the results remained contradictory. This study aimed at evaluating the rs1143634 polymorphism in interleukin-1B gene, a cytokine gene, and the risk of chronic periodontitis with conducting a meta-analysis focusing in ethnicity. A review in literature was performed in several databases to studies published before June 2017. Data extraction was performed by two calibrated investigators and the calculations of the meta-analysis were obtained through Review Manager version 5...
May 18, 2018: Gene
https://www.readbyqxmd.com/read/29777536/periodontitis-and-dental-scaling-associated-with-pyogenic-liver-abscess-a-population-based-case-control-study
#2
Y-T Yeh, B-Y Wang, C-W Lin, S-F Yang, S-W Ho, H-W Yeh, J-Y Huang, Y-C Chang, C-B Yeh
BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the relationship between periodontitis, dental scaling (DS) and pyogenic liver abscesses (PLAs). MATERIAL AND METHODS: A nationwide population-based case-control study was applied using data from the National Health Insurance Research Database in Taiwan. We identified and enrolled 691 PLA patients, who were individually matched by age and sex to 2764 controls. RESULTS: Conditional logistic regression was applied to estimate adjusted odds ratios (aORs) in patients with exposure to periodontitis and DS before PLA...
May 18, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29770451/pregnancy-parity-and-periodontal-disease
#3
REVIEW
Emma L Morelli, Jonathan M Broadbent, Jonathan W Leichter, W Murray Thomson
The belief that a woman's dental health is likely to deteriorate through having children remains common and may originate from the old wives' tale "a tooth per child". As recently as 2005, about 1 in 5 US mothers believed this.1 Epidemiological studies have suggested an association between parity (the number of times a women has given birth) and tooth loss,2-5 and parity and periodontal attachment loss,6 but none has determined whether this association is causal. A number of studies have reported greater severity and extent of gingival inflammation during pregnancy...
May 16, 2018: Australian Dental Journal
https://www.readbyqxmd.com/read/29770238/charlson-comorbidity-index-as-a-predictor-of-periodontal-disease-in-elderly-participants
#4
Jae-Hong Lee, Jung-Kyu Choi, Seong-Nyum Jeong, Seong-Ho Choi
Purpose: This study investigated the validity of the Charlson comorbidity index (CCI) as a predictor of periodontal disease (PD) over a 12-year period. Methods: Nationwide representative samples of 149,785 adults aged ≥60 years with PD (International Classification of Disease, 10th revision [ICD-10], K052-K056) were derived from the National Health Insurance Service-Elderly Cohort during 2002-2013. The degree of comorbidity was measured using the CCI (grade 0-6), including 17 diseases weighted on the basis of their association with mortality, and data were analyzed using multivariate Cox proportional-hazards regression in order to investigate the associations of comorbid diseases (CDs) with PD...
April 2018: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29766516/radiographic-bone-loss-in-a-scottish-non-smoking-type-1-diabetes-mellitus-population-a-bitewing-radiographic-study
#5
Anastasios Plessas, Douglas P Robertson, Penny J Hodge
BACKGROUND: The dental complications of uncontrolled diabetes include reduced salivary flow rate, candidiasis and periodontal manifestations. A recent meta-analysis concluded that diabetes patients have a significantly higher severity, but not extent, of destructive periodontal disease than non-diabetes people. The authors reported that most type-1 diabetes studies using dental radiographic data have not controlled for confounding factors such as smoking. The aim of this cross-sectional study was to compare radiographic alveolar bone loss between type 1 diabetes (T1DM) and non-diabetes (NDM) participants in a Scottish non-smoking population...
May 15, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29764002/effect-of-lifestyle-on-6-year-periodontitis-incidence-or-progression-and-tooth-loss-in-older-adults
#6
Masanori Iwasaki, Wenche S Borgnakke, Hiroshi Ogawa, Takayuki Yamaga, Misuzu Sato, Kumiko Minagawa, Toshihiro Ansai, Akihiro Yoshihara, Hideo Miyazaki
AIM: To evaluate the longitudinal association of combined healthy lifestyle factors with incidence or progression of periodontitis and tooth loss in older adults. MATERIALS AND METHODS: This 6-year study included 374 Japanese 70-year-olds with 7,157 teeth, from a source eligible baseline population of 554 individuals. Four lifestyle factors-cigarette smoking, physical activity, relative weight, and dietary quality-were scored as healthy (1 point) or unhealthy (0 point)...
May 15, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29760403/correlation-between-ultrasound-diagnosed-non-alcoholic-fatty-liver-and-periodontal-condition-in-a-cross-sectional-study-in-japan
#7
Takahiro Iwasaki, Akiko Hirose, Tetsuji Azuma, Tamie Ohashi, Kazutoshi Watanabe, Akihiro Obora, Fumiko Deguchi, Takao Kojima, Atsunori Isozaki, Takaaki Tomofuji
This cross-sectional study investigated the relationship between periodontal condition and ultrasound-diagnosed non-alcoholic fatty liver disease (NAFLD) in a Japanese oral health check population. A total of 1226 consecutive participant were enrolled in the study. Abdominal ultrasonography was applied to diagnose NAFLD. Of the study participants, 339 (27.7%) had ultrasonography-diagnosed NAFLD. The participants with NAFLD had a significantly higher prevalence of probing pocket depth (PPD) ≥ 4 mm (86...
May 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29757485/tobacco-smoking-decreases-clinical-symptoms-of-gingivitis-in-patients-with-type-1-diabetes-a-cross-sectional-study
#8
Mateusz Tarnowski, Anna Duda-Sobczak, Jakub Lipski, Dorota Zozulinska-Ziolkiewicz, Marzena Wyganowska-Swiatkowska
OBJECTIVE: Periodontal disease may develop on the background of microvascular complications of diabetes. However, some modifying factors, such as tobacco smoking should be taken into consideration when assessing risk of development of chronic complications. The aim of the study was the clinical assessment of the periodontal status in patients with type 1 diabetes according to tobacco smoking. SUBJECTS AND METHODS: 362 subjects aged 29 (IQR 22-35) years, type 1 diabetes duration 12 (8-18) years, hemoglobin A1c, HbA1c 8...
May 14, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29754448/periodontal-infection-with-porphyromonas-gingivalis-induces-preterm-birth-and-lower-birth-weight-in-rats
#9
Shanshan Liang, Hongyu Ren, Haiying Guo, Wenyan Xing, Chang Liu, Yaoting Ji, Han Jiang, Ping Zhang, Minquan Du
Preterm birth (PTB), accompanied by low birth weight (LBW) or not, is a syndrome with tremendous risk factors and long-term health consequences for children. In recent decades, overwhelming studies have shown that periodontitis contributes to prematurity and LBW. This study was conducted to determine the link between maternal periodontitis and the pathogenesis of PTB and/or LBW through a rat infection model induced by Porphyromonas gingivalis, an important periodontopathic bacterium. The murine model was established by surgically ligating the left mandibular 1st molars and inoculating with P...
May 13, 2018: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/29752756/soluble-urokinase-type-plasminogen-activator-receptor-is-associated-with-signs-of-periodontitis-in-adolescents
#10
Peter D Skottrup, Gunnar Dahlén, Vibeke Baelum, Rodrigo Lopez
Owing to its molecular stability in body fluids, soluble urokinase-type plasminogen activator receptor (suPAR) is used as a biomarker for the level of systemic inflammation. This study compares the suPAR levels in serum with those in the saliva of adolescents and evaluates their association with the periodontal conditions. Adolescents identified as screen positive (n = 87) or screen negative (n = 73) for periodontitis had saliva and serum samples taken, along with subgingival plaque samples. The concentrations of suPAR were determined in saliva and serum, and 18 microbial species and the immunoglobulin response to them was evaluated...
May 11, 2018: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29747800/periodontitis-and-the-presence-of-adjacent-teeth-may-be-associated-with-a-higher-incidence-of-early-implant-failure
#11
Guo-Hao Lin, Hom-Lay Wang
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Estimating the importance of significant risk factors for early dental implant failure: A Monte Carlo simulation. Buhara O, Pehlivan S. Int J Oral Maxillofac Implants 2018;33(1):161-8. SOURCE OF FUNDING: Not applicable TYPE OF STUDY/DESIGN: Systematic review.
June 2018: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/29747598/an-observation-on-the-severity-of-periodontal-disease-in-past-cigarette-smokers-suffering-from-rheumatoid-arthritis-evidence-for-a-long-term-effect-of-cigarette-smoke-exposure
#12
Márk Antal, Emese Battancs, Márta Bocskai, Gábor Braunitzer, László Kovács
BACKGROUND: Rheumatoid arthritis (RA) and cigarette smoking are both risk factors for periodontal disease (PD). Previous research suggests that systemic inflammatory conditions and cigarette smoking may act in synergy, and their co-occurrence leads to a much higher risk of developing severe stage PD than what the combination of their individual risks would suggest. We originally sought to test this in the case of RA, but it turned out that the majority of our patients were former smokers, who smoked for prolonged periods in the past...
May 10, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29742276/hla-b57-01-shields-people-living-with-hiv-for-significantly-better-periodontal-health
#13
Gundolf Schuettfort, Philipp Leuw, Annette Haberl, Eva Herrmann, Kyu-Hyun Park, Timo Wolf, Christoph Stephan
OBJECTIVES: To assess the association between HLA-B57.01 (Human leukocyte antigen) and clinical parameters of chronic periodontitis in people living with HIV (PLWHIV). MATERIALS AND METHODS: All patients were recruited from the HIVCENTER at the Universityhospital Frankfurt during April 2014 and July 2015. Periodontal examination included Periodontal Screening Index (PSI), Gingivalindex (GI), Bleeding on Probing Index (BOP), Periodontal Probing Depth (PD), Clinical Attachment Level (CAL) and DMF-T Score (decayed, missing, filled teeth)...
May 9, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29738411/risk-factors-for-5-year-prospective-height-loss-among-postmenopausal-women
#14
Xiaodan Mai, Britt Marshall, Kathleen M Hovey, Jill Sperrazza, Jean Wactawski-Wende
OBJECTIVE: Height loss is common in older women and has been associated with increased morbidity and mortality. In this study, we identified factors that could predict prospective height loss in postmenopausal women. METHODS: Height was measured in 1,024 postmenopausal women, enrolled in the Buffalo Osteoporosis and Periodontal Disease Study, at baseline and 5 years later using a fixed stadiometer. Demographics, lifestyle, medical history, and medication use were assessed at baseline...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29737428/the-ratios-of-pro-inflammatory-to-anti-inflammatory-cytokines-in-the-serum-of-chronic-periodontitis-patients-with-and-without-type-2-diabetes-and-or-smoking-habit
#15
Tamires Szeremeske Miranda, Sílvia Lacerda Heluy, Daniele Ferreira Cruz, Hélio Doyle Pereira da Silva, Magda Feres, Luciene Cristina Figueiredo, Poliana Mendes Duarte
OBJECTIVE: This study assessed the impact of chronic periodontitis (CP) and CP associated with type 2 diabetes mellitus (DM) and/or smoking on the serum ratios of pro- to anti-inflammatory cytokines. MATERIALS AND METHODS: Subjects were assigned into one of the following groups: control (n = 25, non-diabetic non-smokers with no history of periodontitis), CP (n = 26, non-diabetic non-smokers with CP), DMCP (n = 30, non-smokers with DM and CP), SCP (n = 27, non-diabetic smokers with CP), and SDMCP (n = 22, smokers with type 2 DM and CP)...
May 8, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29732560/single-nucleotide-polymorphisms-in-long-noncoding-rna-anril-are-not-associated-with-severe-periodontitis-but-with-adverse-cardiovascular-events-among-patients-with-cardiovascular-disease
#16
S Schulz, L Seitter, K Werdan, B Hofmann, H-G Schaller, A Schlitt, S Reichert
BACKGROUND AND OBJECTIVE: Biological plausibility of an association between severe periodontitis and cardiovascular disease (CVD) has been proven. Genetic characteristics play an important role in both complex inflammatory diseases. Polymorphisms (single nucleotide polymorphisms [SNPs]) in the long noncoding RNA, antisense noncoding RNA in the INK4 locus (ANRIL), were shown to play a leading role in both diseases. The primary objectives of the study were to assess, among cardiovascular (CV angiographically proven ≥50% stenosis of a main coronary artery) patients, the impact of ANRIL SNPs rs133049 and rs3217992 on the severity of periodontitis and the previous history of coronary events, as well as on the occurrence of further adverse CV events...
May 6, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29730468/impact-of-obesity-and-aging-on-crestal-alveolar-bone-height-in-mice
#17
Anna Damanaki, Svenja Memmert, Marjan Nokhbehsaim, Abhishek Sanyal, Thorsten Gnad, Alexander Pfeifer, James Deschner
Obesity and aging are associated with periodontitis, which represents a chronic inflammatory disease of the tooth-supporting tissues, i.e. the periodontium. However, if both risk factors also have a negative impact on crestal alveolar bone in a clinically healthy periodontium, has yet to be elucidated and was analyzed in this in-vivo study. Eight C57BL/6 mice were fed a normal diet during the entire study. Half of these mice were sacrificed at week 19 (group 1: younger lean mice), whereas the other half of the animals were sacrificed at week 25 (group 2: older lean mice)...
May 3, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29728099/relationship-between-the-burden-of-major-periodontal-bacteria-and-serum-lipid-profile-in-a-cross-sectional-japanese-study
#18
Youn-Hee Choi, Takayuki Kosaka, Miki Ojima, Shinichi Sekine, Yoshihiro Kokubo, Makoto Watanabe, Yoshihiro Miyamoto, Takahiro Ono, Atsuo Amano
BACKGROUND: The association of periodontal bacteria with lipid profile alteration remains largely unknown, although it has been suggested that chronic periodontitis increases the atherosclerotic risk. This cross-sectional study investigated the relationship between the prevalence and total burden of periodontal bacteria and serum lipid profile. METHODS: Saliva from enrolled participants was collected to detect 4 major periodontal bacteria (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Prevotella intermedia) using Polymerase Chain Reaction method...
May 4, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29723438/chronic-periodontitis-is-associated-to-erectile-dysfunction-a-case-control-study-in-european-population
#19
Amada Martín, Manuel Bravo, Miguel Arrabal, Antonio Magán-Fernández, Francisco Mesa
AIM: To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers and other co-morbidities. METHODS: A case-control study was conducted on 158 male patients. 80 cases with erectile dysfunction according to the International Index of Erectile Function, and 78 controls. Sociodemographic data were gathered and a periodontal examination was performed. Testosterone, lipid profile, C-reactive protein and glycaemic parameters were assessed...
May 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29717494/periodontitis-and-prevalence-of-elevated-aminotransferases-in-the-hispanic-community-health-study-study-of-latinos
#20
Aderonke A Akinkugbe, A Sidney Barritt, Jianwen Cai, Steven Offenbacher, Bharat Thyagarajan, Tasneem Khambaty, Richard Singer, Eric Kallwitz, Gerardo Heiss, Gary D Slade
OBJECTIVE: NAFLD prevalence is greater among Hispanics/Latinos than other racial/ethnic groups and is reported to vary among Hispanic/Latino groups. Experimental animal and human studies demonstrate associations between periodontitis and non-alcoholic fatty liver disease (NAFLD), not yet reported among Hispanics/Latinos. This study examined periodontitis as a novel risk factor that may contribute to the burden of NAFLD among Hispanics/Latinos. METHODS: Data came from 11,914 participants of the Hispanic Community Health Study/Study of Latinos...
May 1, 2018: Journal of Periodontology
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