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risk factor of periodontitis

Andrzej Miskiewicz, Grzegorz Szparecki, Marek Durlik, Grażyna Rydzewska, Ireneusz Ziobrowski, Renata Górska
BACKGROUND: Periodontitis is a major risk factor of systemic diseases with inflammatory etiology. Numerous studies have established the connection between periodontal condition and diabetes, but there are no reports in the literature on the relationship between periodontitis and other pancreas conditions. The activity of pancreatic enzymes is an important parameter of pancreatic damage, and is also a diagnostic marker of acute and chronic pancreatitis, and the bleeding index determines the periodontitis activity...
March 20, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Kyungdo Han, Jun-Beom Park
The present study was performed to assess the risk factors for periodontitis in Korean adults with diabetes. Data from the Korean National Health and Nutrition Examination Survey of the Korean population, conducted between January 2012 and December 2014 were used in the investigation. The presence of periodontitis in participants with diabetes in association with demographic variables and the anthropometric characteristics of the participants was investigated. Multiple logistic regression analyses were used to assess the associations between periodontitis and age, sex, diabetic control and duration of diabetes, following adjustment for confounding factors...
April 2018: Experimental and Therapeutic Medicine
Mona Chowdhury, Neeraj Agrawal, Debabrata Kundu, Nitubroto Biswas
Context: Human leukocyte antigens (HLAs) have an important role in the determination of susceptibility and resistance to periodontal diseases in humans, which may vary from population to population. Aims: The aim of this study was to find out the association of HLA Classes I and II genes with chronic periodontitis in East Indian population. Materials and Methods: In a cross-sectional study design, a total of sixty participants of chronic periodontitis (CP) (mean age: 44...
November 2017: Journal of Indian Society of Periodontology
Umut Aksoy, Kaan Orhan
OBJECTIVES: This study aimed to assess the maxillary sinus mucosal thickening and to associate them with odontogenic conditions using cone-beam computed tomographic (CBCT) images. MATERIALS AND METHODS: CBCT images of 294 patients (143 female, 151 males; age range 18-78 years) with 588 maxillary sinuses were evaluated retrospectively. The anatomic relationship between maxillary sinuses and teeth was determined and classified. The presence of root canal fillings and the periapical lesions of these teeth was also recorded...
March 17, 2018: Clinical Oral Investigations
Katharina Wernicke, Sven Zeissler, Frank C Mooren, Torsten Frech, Stephanie Hellmann, Meike Stiesch, Jasmin Grischke, Silvia Linnenweber, Bernhard Schmidt, Jan Menne, Anette Melk, Pascal Bauer, Andree Hillebrecht, Jörg Eberhard
BACKGROUND: This cross-sectional study investigates the potential association between active periodontal disease and high HbA1c levels in type-2-diabetes mellitus subjects under physical training. METHODS: Women and men with a diagnosis of non-insulin-dependent diabetes mellitus and ongoing physical and an ongoing exercise program were included. Periodontal conditions were assessed according to the CDC-AAP case definitions. Venous blood samples were collected for the quantitative analysis of HbA1c...
March 16, 2018: BMC Oral Health
Murat İnanç Cengiz, Büşra Zengin, Murat İçen, Firüzan Köktürk
BACKGROUND: Occupational injuries cause major health problems in all nations. Coal mining is one of the largest, oldest industries in the world. However, there is relatively little available literature concerning the health status of coal miners. The purpose of this work is to assess the prevalence of periodontal disease among coal miners and provide a basis for planning and evaluating the data from community oral health services. METHODS: A cross-sectional study was conducted 106 men selected based on a stratified cluster sampling procedure...
March 16, 2018: BMC Public Health
James D Beck, Kevin L Moss, Thiago Morelli, Steven Offenbacher
BACKGROUND: This paper focuses on the Periodontal Profile Class (PPC) System that may be more informative and representative of periodontitis phenotypes than current case definitions of periodontitis. This study illustrates the unique aspects of the PPC compared with other periodontal indices for studying associations between periodontal disease and prevalent systemic conditions. METHODS: We computed odds ratios and 95% confidence intervals to compare associations between periodontal disease and prevalent systemic conditions using our new PPC and two traditional indices...
February 2018: Journal of Periodontology
Ana P Ortiz, Daisy González, Jeslie Ramos, Cristina Muñoz, Juan Carlos Reyes, Cynthia M Pérez
BACKGROUND: Despite limited data, research suggests that marijuana use is associated with oral HPV infection and periodontitis, two potential oropharyngeal cancer risk factors. We assessed these associations in a Hispanic adult population in Puerto Rico. METHODS: A cross-sectional study of 735 adults assessed marijuana use, determined through an audio computer-assisted self-interview, and periodontitis and self-collection of oral HPV samples following the National Health and Nutrition Examination Survey methodology...
February 22, 2018: Journal of Periodontology
Tetsuo Kobayashi, Jun-Ichi Kido, Yuichi Ishihara, Kazuhiro Omori, Satoshi Ito, Takato Matsuura, Takashi Bando, Jun Wada, Akira Murasawa, Kiyoshi Nakazono, Akio Mitani, Shogo Takashiba, Toshihiko Nagata, Hiromasa Yoshie
BACKGROUND: A number of studies have suggested a bidirectional relationship of periodontitis with rheumatoid arthritis (RA) and type 2 diabetes mellitus (T2DM). However, the genetic factors that underlie these relationships have not been elucidated. METHODS: We conducted a multicenter case-control study that included 185 patients with RA and chronic periodontitis (CP), 149 patients with T2DM and CP, 251 patients with CP, and 130 systemically and periodontally healthy controls from a cohort of Japanese adults to assess the shared genetic risk factors for RA and CP as well as for T2DM and CP...
February 22, 2018: Journal of Periodontology
Hua Qi, Baosheng Li, Heling Wang, Qing Cai, Xu Quan, Yunxia Cui, Weiyan Meng
BACKGROUND: When presented with a surface or an interface, bacteria often grow as biofilms in which cells are held together by an extracellular matrix. Biofilm formation on implants is an initiating factor for their failure. Porphyromonas gingivalis is the primary etiologic bacteria of initiation and progression of periodontal disease. This microorganism is also the risk factor of many systemic diseases, such as cardiovascular disease, diabetes, and pulmonary infection. To date, no medication that can remove such biofilm has been accepted for clinical use...
March 2018: Journal of Periodontology
Esra Sinem Kemer Doğan, Fatma Yeşim Kırzıoğlu, Burak Doğan, Özlem Fentoğlu, Banu Kale, Süleyman Akif Çarsancaklı, Hikmet Orhan
BACKGROUND: Periodontal disease is shown to be aggravated by an increase in the count of metabolic risk factors. This study aims to evaluate the effects of metabolic risk factors on periodontal parameters and salivary oxidative stress markers related to menopausal status. METHODS: One hundred and seventy-six women were categorized according to menopausal status, either premenopause (Pre/M) (n = 86) or postmenopause (Post/M) (n = 90). The count of metabolic risk factors was evaluated...
March 2018: Journal of Periodontology
K Tabeta, M Hosojima, M Nakajima, S Miyauchi, H Miyazawa, N Takahashi, Y Matsuda, N Sugita, Y Komatsu, K Sato, T Ishikawa, K Akiishi, K Yamazaki, K Kato, A Saito, H Yoshie
BACKGROUND AND OBJECTIVES: Previous reports suggest that several serum biomarkers play roles in the pathogenesis, inflammatory response, and oxidative stress in periodontitis caused by bacterial infections, linking chronic periodontitis to atherosclerotic vascular disease (ASVD). The aim of this preliminary study was to investigate, in a Japanese cross-sectional community survey, potential serum biomarkers of periodontitis that are associated with ASVD and chronic periodontitis. MATERIAL AND METHODS: The study cohort included a total of 108 male subjects who underwent annual health examinations...
March 8, 2018: Journal of Periodontal Research
Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Mehrnoosh Moudi
Background: Interleukin-10 (IL-10) is an anti-inflammatory cytokine that has important roles in the periodontal diseases. The IL10-1082, -819, and -592 polymorphisms in the promoter region of IL-10 gene have been associated with various IL-10 expressions. The aim of this study was to investigate the association between these gene polymorphisms with chronic periodontitis in a sample of Iranian populations from Southeast of Iran. Materials and Methods: IL-10 single nucleotide polymorphisms were analyzed in 210 patients with chronic periodontitis (CP) and 100 individuals without CP by polymerase chain reaction-restriction fragment length polymorphism method...
January 2018: Dental Research Journal
Uma Sudhakar, Ramakrishnan Thyagarajan, Bhagyameena Jeyapal, Sushuruthi Jagadeesh, Parvathee Jayakumar
Background: Periodontal disease is not a conventional bacterial infection but is an inflammatory disease initiated by immune response against a group of microorganisms in susceptible hosts. There are many intriguing researches that unfold the secrets of chronic periodontitis. The current researches in chronic periodontitis are directed toward an approach that respects the scientific relationship between the various risk factors, the genetic factors, and the progression of the disease...
September 2017: Journal of Indian Society of Periodontology
Vladimir W Spolsky, Jason Clague, Debra A Murphy, Steven Vitero, Bruce A Dye, Thomas R Belin, Vivek Shetty
BACKGROUND: Methamphetamine (MA) use is associated with extensive dental caries. The purpose of this study was to determine the prevalence and severity of periodontal disease in a convenience sample of MA users. METHODS: In this cross-sectional survey, MA users were recruited with a combination of snowball sampling and street outreach techniques. Three dentists, trained and calibrated to the oral assessments used in the National Health and Nutrition Survey, measured and recorded the participants' attachment loss, probing depth, and gingival recession...
March 2018: Journal of the American Dental Association
M Maddalone, M Gagliani, C L Citterio, A Pellegatta, M Del Fabbro
AIM: To evaluate retrospectively the prevalence of vertical root fractures (VRF) in a cohort of patients during apical surgery and the factors possibly associated with VRF. METHODOLOGY: The sample consisted of 944 root filled teeth belonging to 768 patients (49.3% males and 50.7% females; mean age 43.5±11.2 years, range 22-68 years), consecutively referred for endodontic surgery over a six-year period. All patients underwent a clinical assessment of their signs and symptoms...
February 25, 2018: International Endodontic Journal
F Carinci, M Martinelli, M Contaldo, R Santoro, F Pezzetti, D Lauritano, V Candotto, D Mucchi, A Palmieri, A Tagliabue, L Tettamanti
Infective endocarditis is a devastating disease with high morbidity and mortality. The link to oral bacteria has been known for many decades and has caused ongoing concern for dentists, patients and cardiologists. The microbiota of the mouth is extremely diverse and more than 700 bacterial species have been detected. Half of them are uncultivable so far. Oral microbiota is not uniform, specific sites exist in the mouth such as tongue, palate, cheek, teeth and periodontal pockets that have their own microbiota...
January 2018: Journal of Biological Regulators and Homeostatic Agents
L Ottria, D Lauritano, L Oberti, V Candotto, F Cura, A Tagliabue, L Tettamanti
HIV infection is one of the major health problem of the last decades. This disease causes a chronic infection that can lead to acquired immunodeficiency syndrome (AIDS). According to the Global AIDS update, released in 2016 by HIV department of World Health Organization (WHO) and by the Joint United Nations Program on HIV/AIDS (UNAIDS), at the end of 2015, 36.7 million people were infected by HIV: 34.9 million of these were adults and 1.8 million were children under 15 years of age. The same report shows that during 2015, 2...
January 2018: Journal of Biological Regulators and Homeostatic Agents
Khushboo Yamima Nand, Anu Mary Oommen, Rabin Kurudamannil Chacko, Vinod Joseph Abraham
Background: Chronic periodontitis is a common cause of poor oral health globally. Those at higher risk of this preventable and easily treatable condition need to be identified so that efforts can be taken to decrease disease burden and subsequent consequences. Aims: The aims of the study were (1) To compare the prevalence of chronic periodontitis among individuals with and without type 2 diabetes, aged 35-65 years from a rural block in Vellore, Tamil Nadu and (2) to assess risk factors for chronic periodontitis among individuals with diabetes...
July 2017: Journal of Indian Society of Periodontology
N Miyoshi, T Tanigawa, S Nishioka, K Maruyama, E Eguchi, K Tanaka, I Saito, K Yamazaki, Y Miyake
BACKGROUND AND OBJECTIVE: Salivary lactate dehydrogenase (LDH) was reported to be a useful parameter for the screening of periodontal disease. We performed a cross-sectional study to verify the usefulness of salivary LDH as a biomarker of periodontitis and to investigate the association of severity of periodontitis with systemic inflammation by measuring salivary LDH and serum high sensitive C-reactive protein (hs-CRP) levels in a community-based middle-aged and elderly population in Japan...
February 15, 2018: Journal of Periodontal Research
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