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Antithyroid peroxidase

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https://www.readbyqxmd.com/read/28176037/fibromyalgia-in-patients-with-thyroid-autoimmunity-prevalence-and-relationship-with-disease-activity
#1
Sema Haliloglu, Bilge Ekinci, Hulya Uzkeser, Hakan Sevimli, Ayse Carlioglu, Pinar Mazlum Macit
Fibromyalgia (FM) is a syndrome characterised by chronic musculoskeletal pain, tenderness and other somatic symptoms. The prevalence of FM is approximately 2-7% in the general global population and is 30-40% in the population of Hashimoto thyroiditis (HT) with a structural pathology. In 2010, new classification criteria for FM were proposed, as an alternative to the American College of Rheumatology (ACR) 1990 criteria. The objectives of the present study were to identify the prevalence of FM in the HT population and evaluate the associated features by using the new diagnostic criteria...
February 7, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28108944/the-seroprevalence-of-antithyroid-peroxidase-antibodies-in-bipolar-families-and-bipolar-twins-results-from-two-longitudinal-studies
#2
G Snijders, L de Witte, E Mesman, S Kemner, R Vonk, R Brouwer, W A Nolen, H A Drexhage, M H J Hillegers
BACKGROUND: Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence's and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (without a mood disorder) compared to controls, suggesting that TPO-Abs might be considered as vulnerability factor (trait marker) for BD development. OBJECTIVES: Here we elucidate, in the same cohorts, but now after 12- and 6-year follow-up, whether TPO-abs should be considered as a 'trait' marker for BD...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28101810/increased-incidence-of-autoimmune-thyroid-disorders-in-patients-with-psoriatic-arthritis-a-longitudinal-follow-up-study
#3
Poupak Fallahi, Silvia Martina Ferrari, Ilaria Ruffilli, Giusy Elia, Mario Miccoli, Andrea Delle Sedie, Lucrezia Riente, Alessandro Antonelli
Contrasting results have been reported about the prevalence of thyroid autoimmunity (AT) and dysfunction (TD) in patients with psoriatic arthritis (PsA). In this study, we pointed to evaluate the incidence of new cases of clinical and subclinical TD in a broad group of patients with PsA versus a control group, matched by age and gender belonging to the same geographic area. PsA patients with TD were excluded firstly, and new cases of thyroid disorders were evaluated in 97 PsA patients and 97 matched controls, who had comparable iodine intake (median follow-up of 74 months in PsA versus 92 in controls)...
January 18, 2017: Immunologic Research
https://www.readbyqxmd.com/read/27967219/a-survey-of-clinical-practice-patterns-in-management-of-graves-disease-in-the-middle-east-and-north-africa
#4
Salem A Beshyah, Aly B Khalil, Ibrahim H Sherif, Mahmoud M Benbarka, Syed Abbas Raza, Wiam Hussein, Ali S Alzahrani, Asma Chadli
OBJECTIVES: Graves' disease (GD) is commonly seen in endocrine clinical practice. The objective of this study was to evaluate the current diagnosis and management of patient's with GD in the Middle East and North Africa (MENA). METHODOLOGY: An electronic survey on management of GD, using an online questionnaire of a large pool of practicing physicians was performed. Responses from 352 eligible and willing physicians were included in this study. They were mostly endocrinologists (157) and internal medicine physicians (116)...
December 14, 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27966298/differentiated-thyroid-cancer-in-patients-with-prolactinoma
#5
Abbas Ali Tam, Cafer Kaya, Cevdet Aydın, Reyhan Ersoy, Bekir Çakır
BACKGROUND/AIM: Increasing evidence is available about the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed at a single site. MATERIALS AND METHODS: The medical records of 182 patients diagnosed with prolactinoma were reviewed retrospectively. Serum prolactin, antithyroglobulin, antithyroid peroxidase antibody, thyroid-stimulating hormone, free T4, and free T3 values and pituitary gland magnetic resonance imaging and thyroid ultrasound reports were evaluated...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27921003/thyroid-function-and-autoimmunity-versus-number-of-pregnancies
#6
Dimitrios Boufas, Andromachi Vryonidou, Georgios Mastorakos, Ioannis Ilias
BACKGROUND: Thyroid autoimmunity may be linked to infertility, in both thyrotropin (TSH)-dependent and TSH-independent fashion. The aim of the present study was to assess this presumed reciprocal relationship of thyroid autoimmunity and pregnancy. METHODS: TSH and antithyroid peroxidase autoantibodies (anti-TPO) were evaluated retrospectively over an eight-year period in 444 Greek women who had previously none or at least one pregnancy (>28 weeks). Statistics were done with analysis of co-variance (ANCOVA) and the Chi square test...
October 2016: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27920545/thyroid-dysfunction-among-type-2-diabetic-female-egyptian-subjects
#7
Ibrahim N Elebrashy, Amr El Meligi, Laila Rashed, Randa F Salam, Elham Youssef, Shaimaa A Fathy
PURPOSE: High prevalence of thyroid disorders is more common in type 1 diabetes compared to type 2 diabetes, due to associated autoimmunity. Hypothyroidism is the most common disorder. The objective was to assess the prevalence of thyroid dysfunction among type 2 diabetic Egyptian females and to find the correlation between metabolic syndrome components and autoimmune thyroid dysfunction. MATERIALS AND METHODS: The study included 62 type 2 diabetic Egyptian females and 27 sex- and age-matched controls...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27919794/diagnostic-utility-of-contrast-enhanced-3d-t1-weighted-imaging-in-acute-cerebral-infarction-associated-with-graves-disease
#8
Yasufumi Gon, Manabu Sakaguchi, Naoki Oyama, Hideki Mochizuki
Graves disease is rarely complicated with cerebrovascular steno-occlusive diseases. Previous studies have suggested several hypotheses for this occurrence, including excess thyroid hormone, which stimulates the sympathetic nervous system, which in turn causes an abnormal hemodynamic response with consequent atherosclerotic changes, and antithyroid antibodies cause local vascular inflammation in patients with Graves disease. However, radiological findings of vasculitis in patients with Graves disease and cerebral infarction remain less known...
December 2, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27906879/presence-of-organ%C3%A2-specific-antibodies-in-patients-with-systemic-sclerosis
#9
Ewa Wielosz, Maria Majdan, Arkadiusz Koszarny, Magdalena Dryglewska, Jacek Tabarkiewicz
INTRODUCTION According to the literature, organ‑specific antibodies may be present in the course of systemic sclerosis (SSc). OBJECTIVES The aim of this study was to assess the prevalence of antithyroid antibodies (antithyroid peroxidase antibodies [anti‑TPO] and antithyroglobulin antibodies) and of antimitochondrial antibodies (AMAs), as well as to evaluate their clinical significance in patients with SSc. PATIENTS AND METHODS The study involved 86 consecutive in‑hospital patients with SSc (32 patients with diffuse cutaneous SSc [dcSSc] and 54 with limited cutaneous SSc [lcSSc])...
October 5, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27904073/a-case-of-familial-dysalbuminemic-hyperthyroxinemia-fdh-in-japan-fdh-as-a-possible-differential-diagnosis-of-syndrome-of-inappropriate-secretion-of-thyroid-stimulating-hormone-sitsh
#10
Sakiko Kobayashi, Jaeduk Yoshimura Noh, Taeko Shimizu, Tomoaki Sato, Isao Kurihara, Kiminori Sugino, Hiroshi Itoh, Koichi Ito
Familial dysalbuminemic hyperthyroxinemia (FDH) is an autosomal dominant condition and is the most commonly inherited euthyroid hyperthyroxinemia in Caucasians. However, it is extremely rare in Asian populations. A 30-year-old Japanese woman, who was incidentally found to have apparent thyroid dysfunction, was admitted to our hospital in 2004. She had extremely elevated serum free thyroxine (FT4), moderately elevated free triiodothyronine (FT3), and normal thyroid-stimulating hormone (TSH). Clinical thyroid examination revealed no abnormalities other than small goiter...
November 30, 2016: Endocrine Journal
https://www.readbyqxmd.com/read/27819113/serum-immunoglobulin-g4-levels-and-graves-disease-phenotype
#11
Carmen Sorina Martin, Anca Elena Sirbu, Minodora Andreea Betivoiu, Suzana Florea, Carmen Gabriela Barbu, Simona Vasilica Fica
PURPOSE: We investigated, at diagnosis, the relationship between serum immunoglobulin G4 levels and the main characteristics of Graves' disease: hyperthyroidism severity, goiter size, presence of active Graves' ophthalmopathy, antithyroid antibodies status, and titer. METHODS: This prospective study included 80 newly diagnosed Graves' disease patients. The main parameters measured at diagnosis: thyroid-stimulating hormone, free thyroxine, free triiodothyronine, total triiodothyronine, thyroglobulin, antithyroid peroxidase antibodies, anti-thyroglobulin antibodies, thyroid-stimulating hormone receptor antibodies, immunoglobulin G4...
February 2017: Endocrine
https://www.readbyqxmd.com/read/27790523/the-effect-of-anti-thyroid-peroxidase-antibodies-on-pregnancy-outcomes-in-euthyroid-women
#12
Monika Meena, Seema Chopra, Vanita Jain, Neelam Aggarwal
INTRODUCTION: Thyroid autoimmunity can have an adverse impact on the outcome of the pregnancy. Although the adverse effects of antithyroid antibodies have been well studied in hypothyroid women, their effects in euthyroid women are not well evaluated. AIM: The study was conducted to assess the overall prevalence of anti-Thyroid Peroxidase (anti-TPO) antibodies in pregnant women and the effect of anti-TPO positivity on the outcome of pregnancy in euthyroid women...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27781146/prevalence-and-impact-of-autoimmune-thyroid-disease-on-myasthenia-gravis-course
#13
Justyna Kubiszewska, Beata Szyluk, Piotr Szczudlik, Zbigniew Bartoszewicz, Małgorzata Dutkiewicz, Maksymilian Bielecki, Tomasz Bednarczuk, Anna Kostera-Pruszczyk
OBJECTIVES: Autoimmune thyroid diseases (ATDs) frequently accompany myasthenia gravis (MG) and may influence its course. We aimed to determine the association and impact of ATD with early- (<50 years), late-onset MG, or thymoma-MG. MATERIALS AND METHODS: Prevalence of ATD was measured in a cross-sectional study of 343 consecutive patients with MG (236 F, 107 M) aged 4-89 years; 83.8% were seropositive, in 2.9%, anti-MuSK antibodies were detected. Concentrations of antithyroid peroxidase antibodies, antithyroglobulin antibodies, antithyrotropin receptor antibodies, and TSH level were measured in all patients...
October 2016: Brain and Behavior
https://www.readbyqxmd.com/read/27756987/cytomorphologic-spectrum-of-lymphocytic-thyroiditis-and-correlation-between-cytological-grading-and-biochemical-parameters
#14
K R Anila, Nileena Nayak, K Jayasree
INTRODUCTION: Chronic lymphocytic thyroiditis [Hashimoto thyroiditis (HT)] is a common thyroid lesion diagnosed on fine-needle aspiration cytology (FNAC). Apart from FNAC, various other parameters, such as clinical features, ultrasonographic findings, antithyroid antibody levels, hormone profiles, and radionuclide thyroid scan, are also taken into consideration in making a diagnosis of HT. AIMS: To grade lymphocytic thyroiditis based on the cytomorphology and to correlate the cytological grades with the levels of antithyroid peroxidase antibody (ATPO), antithyroglobulin antibody (ATG), and thyroid stimulating hormone (TSH)...
July 2016: Journal of Cytology
https://www.readbyqxmd.com/read/27742863/high-prevalence-of-antithyroid-peroxidase-and-antiparietal-cell-antibodies-among-patients-with-type-1-diabetes-mellitus-attending-a-tertiary-diabetes-centre-in-south-africa
#15
Imran M Paruk, Yasmeen Ganie, Sureka Maharaj, Fraser J Pirie, Vasudevan G Naidoo, Ntombifikile M Nkwanyana, Hilary L Dinnematin, Pratistadevi K Ramdial, Ayesha A Motala
OBJECTIVE: Data on the prevalence of autoimmune thyroid disease (AITD) and gastric autoimmunity in type 1 diabetes mellitus (T1DM) in Africa are limited. The aim of this study was to assess the prevalence of antithyroid peroxidase (TPO-A) and antiparietal cell antibody (PCA) in patients with T1DM at a tertiary diabetes clinic in Durban, South Africa. RESEARCH DESIGN AND METHODS: This was a cross-sectional observational study among subjects attending the adult T1DM clinic at Inkosi Albert Luthuli Hospital...
October 14, 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27734702/-psycho-immuno-endocrinology-of-the-thyroid-gland
#16
Ivan Šterzl, Karolína Absolonová, Petr Matucha
Historically endocrinologists and psychiatrists are aware that disturbances in thyroid disease in beginning or even in clinically intensified states of thyrotoxicosis or hypothyroidism exhibit pathological mental manifestations, masking or potentiating the underlying disease. Immune system disorders cause thyroid organ-specific autoimmune process. This autoimmune thyroid disease binds with a number of disorders in both endocrine or non-endocrine organs. This appears in vascular, neurological, skin, connective tissue, gastrointestinal tract and mental pathology...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27695291/effects-of-low-carbohydrate-diet-therapy-in-overweight-subjects-with-autoimmune-thyroiditis-possible-synergism-with-chrebp
#17
Teresa Esposito, Jean Marc Lobaccaro, Maria Grazia Esposito, Vincenzo Monda, Antonietta Messina, Giuseppe Paolisso, Bruno Varriale, Marcellino Monda, Giovanni Messina
The thyroid is one of the metabolism regulating glands. Its function is to determine the amount of calories that the body has to burn to maintain normal weight. Thyroiditides are inflammatory processes that mainly result in autoimmune diseases. We have conducted the present study in order to have a clear picture of both autoimmune status and the control of body weight. We have evaluated the amount of either thyroid hormones, or antithyroid, or anti-microsomal, or anti-peroxidase antibodies (Abs) in patients with high amounts of Abs...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27688922/delirious-mania-associated-with-autoimmune-gastrothyroidal-syndrome-of-a-mid-life-female-the-role-of-hashimoto-encephalopathy-and-a-3-year-follow-up-including-serum-autoantibody-levels
#18
Udo Bonnet, Claudia Selle, Ralf Kuhlmann
We report the case study of a 57-year-old Caucasian female with steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), commonly termed Hashimoto encephalopathy (HE). This presentation includes one of the longest lasting follow-up studies of HE considering the neuropsychiatric symptoms (here delirium, mania, and EEG-slowing) and their relation to serum autoantibody levels. Antithyroid-peroxidase autoantibodies, the hallmark of autoimmune thyroiditis, were found in the serum and also in the cerebrospinal fluid...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27639840/steroid-responsive-encephalopathy-associated-with-autoimmune-thyroiditis-sreat-characteristics-treatment-and-outcome-in-251-cases-from-the-literature
#19
REVIEW
Charlotte Laurent, Jean Capron, Bluenn Quillerou, Guy Thomas, Sonia Alamowitch, Olivier Fain, Arsène Mekinian
BACKGROUND: Steroid-responsive encephalopathy and associated autoimmune thyroiditis (SREAT) is characterized by encephalopathy and the presence of antithyroid antibodies. We describe the clinical presentation, outcome and treatments for SREAT by a systematic review of the literature. METHODS: MEDLINE via PubMed, Web of Science and the Cochrane Library were searched for articles published until 2015. Inclusion criteria were unexplained encephalopathy with antithyroid antibodies...
December 2016: Autoimmunity Reviews
https://www.readbyqxmd.com/read/27639435/-repeated-in-vitro-fertilization-failure-abnormalities-identified-in-the-diagnostic-assessment
#20
M Lambert, C Hocké, C Jimenez, S Frantz, A Papaxanthos, H Creux
OBJECTIVES: Investigate the proportion of abnormalities identified on the diagnostic assessment performed after at least two previous failed IVF attempts. Discuss the real benefit of this evaluation. METHODS: Retrospective descriptive study. Between January 2008 and January 2012, 205 couples with at least two consecutive failed IVF attempts had a diagnosis evaluation which consisted in couple's karyotypes; autoimmune and haemostasis biological check-up, pelvic ultrasound-Doppler and hysteroscopy for women...
October 2016: Gynécologie, Obstétrique & Fertilité
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