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Caili Huang, Yu Chai, Yufeng Jiang, Joe Forth, Paul D Ashby, Matthias Michael Lothar Arras, Kunlun Hong, Gregory Scott Smith, Panchao Yin, Thomas P Russell
Polyoxometalates (POMs) using {Mo72V30} as an example, dissolved in water, can interact with amine-terminated polydimethylsiloxane (PDMS-NH2) dissolved in toluene at the water/toluene interface to form POM-surfactants that significantly lower the interfacial tension and can be used to stabilize liquids via interfacial elasticity. The jamming of the POM-surfactants at the water/oil interface, with consequent wrinkling, occurs with a decrease in the interfacial area. The packing density of the POM-surfactants at the interface can be tuned by varying the strength of screening with the addition of cations with differing hydrated radii...
March 20, 2018: Nano Letters
Elizabeth M White, Jessica G Smith, Rebecca L Trotta, Matthew D McHugh
OBJECTIVES: To investigate whether care in a hospital with more nurses holding at least a Bachelor of Science in Nursing (BSN) degree is associated with lower mortality for individuals with Alzheimer's disease and related dementias (ADRD) undergoing surgery ADRD. DESIGN: Cross-sectional data from 2006-07 Medicare claims were linked with the Multi-State Nursing Care and Patient Safety Survey of nurses in 4 states. SETTING: Adult, nonfederal, acute care hospitals in California, Florida, New Jersey, and Pennsylvania (N=531)...
March 20, 2018: Journal of the American Geriatrics Society
C Melissa Miner, Jennifer L Burnaford, Richard F Ambrose, Liam Antrim, Heath Bohlmann, Carol A Blanchette, John M Engle, Steven C Fradkin, Rani Gaddam, Christopher D G Harley, Benjamin G Miner, Steven N Murray, Jayson R Smith, Stephen G Whitaker, Peter T Raimondi
Disease outbreaks can have substantial impacts on wild populations, but the often patchy or anecdotal evidence of these impacts impedes our ability to understand outbreak dynamics. Recently however, a severe disease outbreak occurred in a group of very well-studied organisms-sea stars along the west coast of North America. We analyzed nearly two decades of data from a coordinated monitoring effort at 88 sites ranging from southern British Columbia to San Diego, California along with 2 sites near Sitka, Alaska to better understand the effects of sea star wasting disease (SSWD) on the keystone intertidal predator, Pisaster ochraceus...
2018: PloS One
Andrew S Moon, Walter Smith, Sawyer Mullen, Brent A Ponce, Gerald McGwin, Ashish Shah, Sameer M Naranje
BACKGROUND: The association between marijuana use and surgical procedures is a matter of increasing societal relevance that has not been well studied in the literature. The primary aim of this study is to evaluate the relationship between marijuana use and in-hospital mortality, as well as to assess associated comorbidities in patients undergoing commonly billed orthopedic surgeries. METHODS: The National Inpatient Sample (NIS) database from 2010 to 2014 was used to determine the odds ratios for the associations between marijuana use and in-hospital mortality, heart failure (HF), stroke, and cardiac disease (CD) in patients undergoing five common orthopedic procedures: hip (THA), knee (TKA), and shoulder arthroplasty (TSA), spinal fusion, and traumatic femur fracture fixation...
March 20, 2018: Substance Abuse
Tanya Eadie, Lauren Faust, Susan Bolt, Mara Kapsner-Smith, Rebecca Hunting Pompon, Carolyn Baylor, Neal Futran, Eduardo Méndez
Objective The purpose of this study was to examine the unique contribution of psychosocial factors, including perceived social support, depression, and resilience to communicative participation, among adult survivors of head and neck cancer (HNC). Study Design Cross-sectional. Setting University-based laboratory and speech clinic. Subjects and Methods Adult survivors of HNC who were at least 2 years posttreatment for HNC completed patient-reported outcome measures, including those related to communicative participation and psychosocial function...
March 1, 2018: Otolaryngology—Head and Neck Surgery
Louise Ewing, Elizabeth Pellicano, Harriet King, Laura Lennuyeux-Comnene, Emily K Farran, Annette Karmiloff-Smith, Marie L Smith
Unusual patterns of fixation behavior in individuals with autism spectrum disorder during face tasks hint at atypical processing strategies that could contribute to diminished face expertise in this group. Here, we use the Bubbles reverse correlation technique to directly examine face-processing strategies during identity judgments in children with and without autism, and typical adults. Results support a qualitative atypicality in autistic face processing. We identify clear differences not only in the specific features relied upon for face judgments, but also more generally in the extent to which they demonstrate a flexible and adaptive profile of information use...
March 20, 2018: Developmental Neuropsychology
Samrat Yeramaneni, Jeffrey L Gum, Leah Y Carreon, Eric O Klineberg, Justin S Smith, Amit Jain, Richard A Hostin
BACKGROUND: Readmissions following adult spinal deformity surgical procedures frequently occur, placing a substantial burden on patients and providers. Existing literature on readmission costs, including reason-specific readmission costs, is limited. The purposes of this study were to determine the most expensive reasons for readmission, to assess the impact of reasons and timing on readmission costs, and to estimate the drivers of total costs associated with adult spinal deformity surgical procedures...
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
(no author information available yet)
No abstract text is available yet for this article.
March 20, 2018: Medical Teacher
Arash Mehdizadeh, Bruce S Gardiner, Michael Lavagnino, David W Smith
The composition of extracellular matrix (ECM) in tendon depends on the secretion profile of resident cells known as tenocytes. For tissues with a mechanical role like tendon, mechanical strain is known to play an important role in determining the secretion profile of resident cells. Previously we explored the idea of estimating average concentrations of ECM molecules as a function of tendon strain magnitude and number of loading cycles. Specifically, we developed a model of the mechanical fatigue damage of tendon collagen fibers and introduced elementary cell responses (ECRs) by which local cellular-level responses to the strain environment, combined with the fatigue damage model, were scaled up to predict tissue-level responses...
March 20, 2018: Connective Tissue Research
Philip L Smith, Daniel R Little
The dominant paradigm for inference in psychology is a null-hypothesis significance testing one. Recently, the foundations of this paradigm have been shaken by several notable replication failures. One recommendation to remedy the replication crisis is to collect larger samples of participants. We argue that this recommendation misses a critical point, which is that increasing sample size will not remedy psychology's lack of strong measurement, lack of strong theories and models, and lack of effective experimental control over error variance...
March 19, 2018: Psychonomic Bulletin & Review
Karen Müller Smith
GABAergic interneuron loss, maturational delay or imbalance of glutamatergic to GABAergic signaling has been implicated in several neuropsychiatric disorders including Tourette syndrome and attention-deficit/hyperactivity disorder (ADHD). In schizophrenia, decreases in parvalbumin (PV), somatostatin (Sst) and glutamic acid decarboxylase (GAD) RNA have been observed and seem to indicate a failure in maturation in PV and Sst neurons. In Tourette syndrome, which has a high level of comorbid ADHD, reduced numbers of parvalbumin expressing neurons have been observed in the basal ganglia of affected patients...
March 19, 2018: Attention Deficit and Hyperactivity Disorders
Nicole L Matthews, Beatriz C Orr, Katrina Warriner, Mary DeCarlo, Mia Sorensen, Jessica Laflin, Christopher J Smith
The original version of this article unfortunately contained a mistake.
March 19, 2018: Journal of Autism and Developmental Disorders
Steven J Weissbart, Alan J Wein, Ariana L Smith
PURPOSE OF REVIEW: There are advantages and disadvantages of subspecialty certification for physicians, trainees, patients, and society at large. As female pelvic medicine and reconstructive surgery (FPMRS) became the second subspecialty of urology to offer subspecialty certification, understanding the effects of FPMRS subspecialty certification on the healthcare system is important. RECENT FINDINGS: While subspecialty certification may improve training, identify experts, and ultimately lead to improved patient outcomes, certification might also be unnecessary for some physicians, weaken residency training, and limit the number of physicians who are deemed qualified to offer certain treatments...
March 19, 2018: Current Urology Reports
Tasneem Kaleem, Grace Li Smith, Robert C Miller
No abstract text is available yet for this article.
January 2018: Advances in Radiation Oncology
Christopher Vernazza, Lauren Anderson, Andrew Ian Hunter, Helen Christine Leck, Stephen Daniel O'Connor, Gillian Rose Smith, Richard Joseph Stokes, Sarah Rolland
Introduction: Given the limited evidence about the benefits of orthodontic treatment, many health care systems have rationed access to orthodontic care with the Index of Orthodontic Treatment Need (IOTN) being one tool used to attempt to allocate resources based on need. However, it is not clear whether patient and public valuations of different levels of need (as described by the IOTN) reflect the resource allocation decisions. The aim of this project was therefore to determine the values parents placed on correction of malocclusions at different IOTN levels using the willingness to pay (WTP) technique...
April 1, 2018: JDR Clinical and Translational Research
Penny Wang, Stacy E Smith, Rajesh Garg, Fengxin Lu, Alyssa Wohlfahrt, Anarosa Campos, Kathleen Vanni, Zhi Yu, Daniel H Solomon, Seoyoung C Kim
Objectives: Dual-energy CT (DECT) scan is a sensitive and specific tool used to visualise and quantify monosodium urate (MSU) crystal deposits in the joints. Few studies have examined MSU crystal deposits in patients with asymptomatic hyperuricemia (ie, hyperuricemia in the absence of gout) using DECT. Methods: We conducted a prospective, non-interventional cross-sectional study to detect MSU crystal deposits on DECT scans among patients with asymptomatic hyperuricemia...
2018: RMD Open
Judith A Smith
Protein folding in the endoplasmic reticulum (ER) is an essential cell function. To safeguard this process in the face of environmental threats and internal stressors, cells mount an evolutionarily conserved response known as the unfolded protein response (UPR). Invading pathogens induce cellular stress that impacts protein folding, thus the UPR is well situated to sense danger and contribute to immune responses. Cytokines (inflammatory cytokines and interferons) critically mediate host defense against pathogens, but when aberrantly produced, may also drive pathologic inflammation...
2018: Frontiers in Immunology
Gabrielle Bradshaw, Robbie R Lualhati, Cassie L Albury, Neven Maksemous, Deidre Roos-Araujo, Robert A Smith, Miles C Benton, David A Eccles, Rod A Lea, Heidi G Sutherland, Larisa M Haupt, Lyn R Griffiths
Background: We investigated the molecular etiology of a young male proband with confirmed immunodeficiency of unknown cause, presenting with recurrent bacterial and Varicella zoster viral infections in childhood and persistent lymphopenia into early adulthood. Aim: To identify causative functional genetic variants related to an undiagnosed primary immunodeficiency. Method: Whole genome microarray copy number variant (CNV) analysis was performed on the proband followed by whole exome sequencing (WES) and trio analysis of the proband and family members...
2018: Frontiers in Immunology
Anas Boulemden, Gemma L Malin, Suzanne V F Wallace, Amr Mahmoud, William H T Smith, Adam A Szafranek
We report the case of a 44-year-old pregnant woman who was diagnosed with symptomatic severe mitral stenosis that did not respond to optimal medical therapy and balloon valvuloplasty. After a multidisciplinary team discussion on the timing and risks of interventions and postoperative optimization of peripartum anticoagulation, the patient underwent mechanical mitral valve replacement during the 2nd trimester of pregnancy. The outcome was excellent for the mother and the infant. This case emphasizes the importance of a multidisciplinary approach in managing unusual cases...
February 2018: Texas Heart Institute Journal
Sarina R Isenberg, Norah L Crossnohere, Manali I Patel, Alison Conca-Cheng, John F P Bridges, Sandy M Swoboda, Thomas J Smith, Timothy M Pawlik, Matthew Weiss, Angelo E Volandes, Anne Schuster, Judith A Miller, Carolyn Pastorini, Debra L Roter, Rebecca A Aslakson
OBJECTIVE: Video-based advanc care planning (ACP) tools have been studied in varied medical contexts; however, none have been developed for patients undergoing major surgery. Using a patient- and family-centredness approach, our objective was to implement human-centred design (HCD) to develop an ACP decision support video for patients and their family members when preparing for major surgery. DESIGN AND METHODS: The study investigators partnered with surgical patients and their family members, surgeons and other health professionals to design an ACP decision support video using key HCD principles...
March 18, 2018: BMJ Supportive & Palliative Care
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