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https://www.readbyqxmd.com/read/29328008/-posttraumatic-stress-disorder-current-insights-in-diagnostics-treatment-and-prevention
#1
A Lok, J L Frijling, M van Zuiden
- Posttraumatic stress disorder (PTSD) is a psychiatric disorder that may develop after traumatic events.- PTSD is one of the most prevalent psychiatric disorders in the Netherlands, with an estimated lifetime prevalence of 7%.- Recurrent re-experiencing of the traumatic event is the most characteristic PTSD symptom.- Recognition of PTSD may be hampered by the heterogeneous symptomatology, avoidance to talk about the trauma and highly frequent comorbid psychiatric and somatic comorbidity.- Feelings of guilt and shame may also influence reported trauma history...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29318339/-e-health-in-diagnosis-and-therapy-of-mental-disorders-will-therapists-soon-become-superfluous
#2
REVIEW
Stefan Lüttke, Martin Hautzinger, Kristina Fuhr
Digital media, online programs, and electronic health systems are available and easily accessible for diagnostic, prevention, and intervention of somatic and psychiatric disorders. These modern tools can assess objective as well as subjective information about acute symptoms, wellbeing, life quality, sleep, physiological indicators, etc. Wearables and apps collect data over days and weeks in the real world of subjects. This information can be used to document baselines as well as changes over time influenced by events or interventions...
January 9, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29317008/patients-with-advanced-cancer-and-depression-report-a-significantly-higher-symptom-burden-than-non-depressed-patients
#3
Kjersti Støen Grotmol, Hanne C Lie, Jon Håvard Loge, Nina Aass, Dagny Faksvåg Haugen, Patrick C Stone, Stein Kaasa, Marianne Jensen Hjermstad
OBJECTIVE: Clinical observations indicate that patients with advanced cancer and depression report higher symptom burden than nondepressed patients. This is rarely examined empirically. Study aim was to investigate the association between self-reported depression disorder (DD) and symptoms in patients with advanced cancer controlled for prognostic factors. METHOD: The sample included 935 patients, mean age 62, 52% males, from an international multicentre observational study (European Palliative Care Research Collaborative - Computerised Symptom Assessment and Classification of Pain, Depression and Physical Function)...
January 10, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29311328/modeling-lethal-x-linked-genetic-disorders-in-pigs-with-ensured-fertility
#4
Hitomi Matsunari, Masahito Watanabe, Kazuaki Nakano, Shin Enosawa, Kazuhiro Umeyama, Ayuko Uchikura, Sayaka Yashima, Toru Fukuda, Nikolai Klymiuk, Mayuko Kurome, Barbara Kessler, Annegret Wuensch, Valeri Zakhartchenko, Eckhard Wolf, Yutaka Hanazono, Masaki Nagaya, Akihiro Umezawa, Hiromitsu Nakauchi, Hiroshi Nagashima
Genetically engineered pigs play an indispensable role in the study of rare monogenic diseases. Pigs harboring a gene responsible for a specific disease can be efficiently generated via somatic cell cloning. The generation of somatic cell-cloned pigs from male cells with mutation(s) in an X chromosomal gene is a reliable and straightforward method for reproducing X-linked genetic diseases (XLGDs) in pigs. However, the severe symptoms of XLGDs are often accompanied by impaired growth and reproductive disorders, which hinder the reproduction of these valuable model animals...
January 8, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29306954/management-of-functional-somatic-syndromes-and-bodily-distress
#5
Peter Henningsen, Stephan Zipfel, Heribert Sattel, Francis Creed
Functional somatic syndromes (FSS), like irritable bowel syndrome or fibromyalgia and other symptoms reflecting bodily distress, are common in practically all areas of medicine worldwide. Diagnostic and therapeutic approaches to these symptoms and syndromes vary substantially across and within medical specialties from biomedicine to psychiatry. Patients may become frustrated with the lack of effective treatment, doctors may experience these disorders as difficult to treat, and this type of health problem forms an important component of the global burden of disease...
January 6, 2018: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/29306907/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-2-chronic-hypocapnia-and-hypercapnia-in-the-medical-practice
#6
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (Sikter et al. 2017a). Human stress response often coexists with persistent hypocapnia or hypercapnia - developing via psychosomatic pathomechanism - which can lead to mental and psychosomatic illnesses. Chronic hypocapnia mainly generates hyperarousal disorders which may be reversible for an extended time, however, vicious cycles may start when hypoxia and/or severe somatic diseases are simultaneously present (commonly in the elderly), which conditions often end with death without medical help...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29298535/multimethod-assessment-of-baseline-depression-and-relationship-to-hepatitis-c-treatment-discontinuation
#7
Jeffrey J Weiss, Sarah Prieto, Norbert Bräu, Douglas T Dieterich, Sue M Marcus, Alicia Stivala, Jack M Gorman
Objective The primary study objective is to determine which measures of depression are associated with early discontinuation of hepatitis C virus infection treatment and to determine which measure best characterizes the depression that develops during treatment. Methods Seventy-eight treatment-naïve subjects who initiated pegylated interferon/ribavirin treatment for hepatitis C virus infection were included. Baseline depression was assessed with the Structured Interview for the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), the Hamilton Depression Rating Scale, and the Beck Depression Inventory-II...
January 1, 2018: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29289966/intestinal-microbiota-a-key-to-understanding-the-pathophysiology-of-anorexia-nervosa
#8
REVIEW
Hanna Karakuła-Juchnowicz, Hanna Pankowicz, Dariusz Juchnowicz, Jose Luis Valverde Piedra, Teresa Małecka-Massalska
Anorexia nervosa (AN) is a psychiatric disorder related to very serious consequences for physical and mental health of patients. Due to a complex clinical picture, which consists of anumber of somatic and mental symptoms, AN remains a serious problem of modern medicine and encourages the search for possible causes of the illness and new, more effective therapies. The recent reports emphasize the role of the intestinal microbiota in regulation of body weight. In this light, the hypothesis that in AN patients there is a significant imbalance of the intestinal microbiota, which contributes to the pathogenesis of the illness, seems interesting...
October 29, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29284975/dental-implants-a-remote-option-in-case-of-somatic-delusion-disorder
#9
Thanvir Mohamed Niazi, G Ulaganathan, S Kalaiselvan, R Lambodharan, R Mahalakshmi, M Sophia, V Usha Giridhar
A 29-year-old female was referred by a psychiatrist for dental implantation and prosthodontic rehabilitation, as she had all her healthy permanent teeth extracted within a span of 2-6 months, due to somatic delusional disorder. She presently refuses artificial dentures and implants with the fear of having worms in her teeth and the fear not yet allayed. The patient cannot be treated for her edentulous state until her psychiatric symptoms are treated. This is the limitation for the implant surgeon where service rendered is impaired in spite of advanced professional skills, ideal patient ridge, and other factors, just where the patient is not mentally prepared for the dental rehabilitation procedures...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29280393/internet-gaming-disorder-and-online-gambling-disorder-clinical-and-personality-correlates
#10
Nuria Mallorquí-Bagué, Fernando Fernández-Aranda, María Lozano-Madrid, Roser Granero, Gemma Mestre-Bach, Marta Baño, Amparo Del Pino-Gutiérrez, Mónica Gómez-Peña, Neus Aymamí, José M Menchón, Susana Jiménez-Murcia
Background and aims The recent growth of Internet use has led to an increase of potentially problematic behaviors that can be engaged online, such as online gambling or Internet gaming. The aim of this study is to better conceptualize Internet gaming disorder (IGD) by comparing it with gambling disorder (GD) patients who only gamble online (online GD). Methods A total of 288 adult patients (261 online GD and 27 IGD) completed self-reported questionnaires for exploring psychopathological symptoms, food addiction (FA), and personality traits...
December 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29278731/a-test-of-the-adaptive-network-explanation-of-functional-disorders-using-a-machine-learning-analysis-of-symptoms
#11
Christos Melidis, Susan L Denham, Michael E Hyland
The classification and etiology of functional disorders is controversial. Evidence supports both psychological and biological (disease) models that show, respectively, that functional disorders should be classified as one (bodily distress syndrome) and many (e.g., irritable bowel syndrome (IBS), fibromyalgia syndrome (FMS), and chronic fatigue syndrome (CFS)). Two network models (symptom network and adaptive network) can explain the specificity and covariation of symptomatology, but only the adaptive network model can explain the covariation of the somatic symptoms of functional disorders...
December 23, 2017: Bio Systems
https://www.readbyqxmd.com/read/29276971/child-abuse-and-neglect-in-institutional-settings-cumulative-lifetime-traumatization-and-psychopathological-long-term-correlates-in-adult-survivors-the-vienna-institutional-abuse-study
#12
Brigitte Lueger-Schuster, Matthias Knefel, Tobias M Glück, Reinhold Jagsch, Viktoria Kantor, Dina Weindl
Child maltreatment (CM) in foster care settings (i.e., institutional abuse, IA) is known to have negative effects on adult survivor's mental health. This study examines and compares the extent of CM (physical, emotional, and sexual abuse; physical and emotional neglect) and lifetime traumatization with regard to current adult mental health in a group of survivors of IA and a comparison group from the community. Participants in the foster care group (n = 220) were adult survivors of IA in Viennese foster care institutions, the comparison group (n = 234) consisted of persons from the Viennese population...
December 22, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29275781/physical-comorbidity-in-patients-with-multiple-functional-somatic-syndromes-a-register-based-case-control-study
#13
Marie Weinreich Petersen, Elisabeth Lundsgaard Skovenborg, Charlotte Ulrikka Rask, Marian Dalgaard Høeg, Eva Ørnbøl, Andreas Schröder
BACKGROUND: Patients with multiple functional somatic syndromes show markedly reduced functioning and numerous somatic symptoms that cannot be explained by conventionally-defined physical disease. Whilst the comorbidity of functional somatic syndromes with mental disorders is well-known, knowledge about physical comorbidity and mortality is scarce. AIM: To compare number of physical diseases between patients with multiple functional somatic syndromes (operationalized as multi-organ bodily distress syndrome) and the general population with regard to: 1) All conventionally-defined physical diseases, and 2) Severe mortality-associated physical diseases...
January 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29261783/somatic-instability-of-the-expanded-gaa-repeats-in-friedreich-s-ataxia
#14
Ashlee Long, Jill S Napierala, Urszula Polak, Lauren Hauser, Arnulf H Koeppen, David R Lynch, Marek Napierala
Friedreich's ataxia (FRDA) is a genetic neurodegenerative disorder caused by transcriptional silencing of the frataxin gene (FXN) due to expansions of GAA repeats in intron 1. FRDA manifests with multiple symptoms, which may include ataxia, cardiomyopathy and diabetes mellitus. Expanded GAA tracts are genetically unstable, exhibiting both expansions and contractions. GAA length correlates with severity of FRDA symptoms and inversely with age of onset. Thus, tissue-specific somatic instability of long GAA repeats may be implicated in the development of symptoms and disease progression...
2017: PloS One
https://www.readbyqxmd.com/read/29247552/ehlers-danlos-syndrome-in-a-young-woman-with-anorexia-nervosa-and-complex-somatic-symptoms
#15
Michelle Lee, Mattias Strand
The Ehler-Danlos syndromes (EDS) are a group of clinically heterogeneous connective tissue disorders characterized by joint hypermobility, hyperextensibility of the skin, and a general connective tissue fragility that can induce symptoms from multiple organ systems. We present a case of comorbid anorexia nervosa and EDS in a 23-year old woman with a multitude of somatic symptoms that were initially attributed to the eating disorder but that were likely caused by the underlying EDS. Various EDS symptoms, such as gastrointestinal complaints, smell and taste abnormalities, and altered somatosensory awareness may resemble or mask an underlying eating disorder, and vice versa...
December 16, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29241946/youth-with-psychogenic-non-syncopal-collapse-have-more-somatic-and-psychiatric-symptoms-and-lower-perceptions-of-peer-relationships-than-youth-with-syncope
#16
Geoffrey L Heyer
BACKGROUND: Little is known about somatic and psychiatric symptoms and perceived peer relationships of patients with psychogenic nonsyncopal collapse. OBJECTIVE: This study aimed to compare somatic and psychiatric symptoms and other elements potentially related to functional neurological symptom disorders between youth with psychogenic nonsyncopal collapse and those with neurally mediated syncope. METHODS: Before testing, patients completed a structured interview and questionnaire addressing current symptoms, previous psychiatric diagnoses, referrals, diagnostic testing, prescribed medications, and patient self-ratings of anxiety, depression, and perceived peer relationships...
November 20, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29238391/functional-impairment-and-painful-physical-symptoms-in-patients-with-major-depressive-disorder-treated-with-antidepressants-real-world-evidence-from-the-middle-east
#17
Jihyung Hong, Diego Novick, Maria Victoria Moneta, Ahmed El-Shafei, Héctor Dueñas, Josep Maria Haro
Background: The Global Burden of Disease 2010 study reported the relative size of major depressive disorder (MDD) burden to be greater in the Middle East and North Africa than anywhere else. However, little research has been carried out to examine the comparative effectiveness of antidepressants in this region. Objective: To assess and compare functioning levels in Middle Eastern patients with MDD treated with either duloxetine or a selective serotonin reuptake inhibitor (SSRI), and to examine the impacts of depression-related pain on functioning by the type of treatment...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29237208/-acceptance-and-commitment-therapy-in-the-treatment-of-chronic-disease
#18
Katharina Kuba, Gregor Weißflog
Acceptance and Commitment Therapy (ACT) is an intervention representing a transdiagnostic and contextual approach that assumes that psychological suffering is caused by experiential avoidance. The primary intention of ACT is not to eliminate symptoms and to treat mental disorders. Instead, ACT aims to increase psychological flexibility, i. e. to broaden the repertoire of cognitions and behaviors when facing inner and outer aversive events or experiences. Psychological flexibility can be enhanced by working with the 6 core components of the ACT model...
December 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29231914/determinants-of-late-life-depression-in-residents-of-long-term-care-facility
#19
Urszula Horwath, Katarzyna Szczerbińska
Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF). Late-life depression refers to depressive symptoms that arise in adults older than 65 years. According to literature review, older people tend to differ from middle-aged adults in presentation of depression. AIM: Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF)...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29227962/the-impact-of-an-add-on-video-assisted-structured-aerobic-exercise-module-on-mood-and-somatic-symptoms-among-women-with-depressive-disorders-study-from-a-tertiary-care-centre-in-india
#20
Amrita Roy, Radhakrishnan Govindan, Kesavan Muralidharan
BACKGROUND: The evidence in favor of exercise as a treatment for depression is compelling, but what kind of exercise, how much, how often, and at what intensity is necessary to make a significant difference. There is serious dearth of such data from India, in particular. We examined the impact of low-moderate intensity aerobic exercises on mood and somatic symptoms among women with depressive disorders. METHODS: A pre test- post test control group design was adopted with a sample size of 40 (20 subjects randomized to both experimental and control group) women inpatients diagnosed with depressive disorder at a tertiary care centre, Bengaluru, India...
December 5, 2017: Asian Journal of Psychiatry
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