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https://www.readbyqxmd.com/read/29786675/combined-effectiveness-of-honey-and-immunonutrition-on-bacterial-translocation-secondary-to-obstructive-jaundice-in-rats-experimental-study
#1
Serhat Oguz, Omer Salt, Abdil C Ibis, Saban Gurcan, Dogan Albayrak, Tulin Yalta, Tamer Sagiroglu, Cengiz Erenoglu
BACKGROUND Obstructive jaundice is a serious, life-threatening condition that can lead to death as a result of sepsis and multiorgan failure due to bacterial translocation. Treatment should be started as soon as possible after diagnosis. MATERIAL AND METHODS Forty 24-week-old male Sprague Dawley rats, with an average weight of 250 g to 300 g, were included in this study. The rats were randomly placed into five groups, each group consisted of eight rats. The sham group underwent only common bile duct (CBD) dissection and no ligation was performed...
May 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29785364/neo-glans-reconstruction-after-glans-amputation-during-circumcision-using-autologous-buccal-mucosal-graft
#2
Andry Giovanny, Irfan Wahyudi, Arry Rodjani
No abstract text is available yet for this article.
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29785192/-panax-notoginseng-promotes-repair-of-colonic-microvascular-injury-in-sprague-dawley-rats-with-experimental-colitis
#3
Shiying Wang, Ping Tao, Lei Zhao, Wangjun Zhang, Hongyi Hu, Jiang Lin
To investigate the therapeutic effects of PN on intestinal inflammation and microvascular injury and its mechanisms, dextran sodium sulfate- (DSS-) or iodoacetamide- (IA-) induced rat colitis models were used. After colitis model was established, PN was orally administered for 7 days at daily dosage of 1.0 g/kg. Obvious colonic inflammation and mucosal injuries and microvessels were observed in DSS- and IA-induced colitis groups. DAI scores, serum concentrations of VEGFA121, VEGFA165, VEGFA165/VEGFA121, IL-6, and TNF- α , and expression of Rap1GAP and TSP1 proteins in the colon were significantly higher while serum concentrations of IL-4 and IL-10 and MVD in colon were significantly lower in the colitis model groups than in the normal control group...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29785183/evaluation-of-reirradiation-in-locally-advanced-head-and-neck-cancers-toxicity-and-early-clinical-outcomes
#4
Amit Bahl, Arun Singh Oinam, Arun Elangovan, Satinder Kaur, Gaurav Trivedi, Roshan Verma, Sudhir Bhandari, Sushmita Ghoshal, Naresh Kumar Panda
Objectives: Locoregional recurrence is the predominant pattern of treatment failure in advanced head and neck cancers. Reirradiation is a useful modality to treat inoperable head and neck cancer patients with recurrent disease. The aim of the present study was to analyze the treatment toxicity and early clinical outcomes in patients undergoing reirradiation. Methods: Twenty patients of head and neck cancers with recurrences or second cancers were evaluated. Reirradiation was done using simultaneous integrated boost volumetric modulated arc therapy (SIB VMAT), intensity modulated radiotherapy (IMRT), or conventional radiotherapy using 6MV photons...
2018: Journal of Oncology
https://www.readbyqxmd.com/read/29785161/prevalence-and-psychological-stress-in-recurrent-aphthous-stomatitis-among-female-dental-students-in-saudi-arabia
#5
Muhammed Ajmal, Lujain Ibrahim, Nada Mohammed, Heba Al-Qarni
Introduction: Recurrent Aphthous Stomatitis (RAS) is a common oral mucosal disorder which is characterized by recurrent ulcerations mainly confined to non-keratinized oral mucosa. Though the exact etiology is imprecise, stress and anxiety were found to be linked with the onset of RAS. The present study was directed to know the prevalence of RAS among female dental students in King Khalid University, to find out the association between RAS and psychological stress and the effectiveness of Hospital Anxiety and Depression scale (HADS) in finding out the psychological profile of RAS patients...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29785160/observational-study-of-the-bisphosphonate-related-osteonecrosis-of-jaws
#6
Andreea Elena Lungu, Madalina Anca Lazar, Andrada Tonea, Horatiu Rotaru, Rares Calin Roman, Mindra Eugenia Badea
Introduction: The bisphosphonate-related osteonecrosis of the jaw was first referred to in 2003. Bisphosphonates action is focused on the osteoclasts. The drastic inhibition of the osteoclastic function is harmful for the jaws which are the only bones of the human skeleton in relative contact with the external environment. The adverse effects of the bisphosphonate-related therapy include the pathology for which they are prescribed, the atypical fractures in pathological bone. Method: The aim of this research was to analyze the risk factors and the treatment methods in case of osteonecrosis of the jaws...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29784985/chronic-rhinosinusitis-with-nasal-polyps-is-characterized-by-dysbacteriosis-of-the-nasal-microbiota
#7
Thanit Chalermwatanachai, Ramiro Vilchez-Vargas, Gabriele Holtappels, Tim Lacoere, Ruy Jáuregui, Frederiek-Maarten Kerckhof, Dietmar H Pieper, Tom Van de Wiele, Mario Vaneechoutte, Thibaut Van Zele, Claus Bachert
Chronic rhinosinusitis with nasal polyp (CRSwNP) patients are often characterized by asthma comorbidity and a type-2 inflammation of the sinonasal mucosa. The mucosal microbiota has been suggested to be implicated in the persistence of inflammation, but associations have not been well defined. To compare the bacterial communities of healthy subjects with CRSwNP patients, we collected nasal swabs from 17 healthy subjects, 21 CRSwNP patients without asthma (CRSwNP-A), and 20 CRSwNP patients with co-morbid asthma (CRSwNP+A)...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784145/the-effect-of-the-use-of-thyme-honey-in-minimizing-radiation-induced-oral-mucositis-in-head-and-neck-cancer-patients-a-randomized-controlled-trial
#8
Melanie Charalambous, Vasilios Raftopoulos, Lefkios Paikousis, Nicos Katodritis, Ekaterini Lambrinou, Dimitrios Vomvas, Morpho Georgiou, Andreas Charalambous
PURPOSE: Radiation-induced oral mucositis is one of the main side effects during and after the treatment of head and neck cancer patients. The study was designed to provide evidence on the effectiveness of thyme honey on oral mucositis management. METHODS: This was a randomised controlled trial (RCT) with 72 head and neck cancer patients who were divided either to the intervention group (thyme honey rinses) or to the control group (saline rinses). Oral mucositis was assessed according to the Radiation Therapy Oncology Group (RTOC criteria), and assessments were performed weekly starting at the 4th week of the radiotherapy for seven weeks and repeated once 6 months later...
June 2018: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/29783860/giant-juvenile-xanthogranuloma-case-report-literature-review-and-algorithm-for-classification
#9
Malika A Ladha, Richard M Haber
Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is referred to as giant; this term encompasses JXG lesions larger than 2.0 cm. In this article, we report a case of a congenital cutaneous giant JXG. In addition, we reviewed and analyzed all cases (n = 51) of giant JXG reported in the English literature...
May 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29783212/changes-in-biochemical-parameters-of-oral-fluid-in-patients-during-the-orthodontic-treatment-with-a-bracket-system-under-the-action-of-a-developed-mucosal-gel-with-probiotic
#10
Anna V Voronkova, Lyubov V Smaglyuk
OBJECTIVE: Introduction: Many research studies involving orthodontic patients focus on changes in levels of oral microbiocenosis after bracket placement. Based upon this the objective of the current study was to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system. The aim: Aim of our study is to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782992/single-ultra-high-dose-cholecalciferol-to-prevent-vitamin-d-deficiency-in-pediatric-hematopoietic-stem-cell-transplantation
#11
Gregory Wallace, Sonata Jodele, Kasiani C Myers, Christopher E Dandoy, Javier El-Bietar, Adam Nelson, Ashley Teusink-Cross, Pooja Khandelwal, Cynthia Taggart, Catherine M Gordon, Stella M Davies, Jonathan C Howell
BACKGROUND: Vitamin D (vitD) deficiency is prevalent among childhood hematopoietic stem cell transplantation (HSCT) recipients and associated with inferior transplant survival at 100 days after transplantation. Achieving and maintaining therapeutic vitD levels in HSCT recipients is extremely challenging in the first 3-6 months after transplant due to poor compliance in the setting of mucositis, and concomitant use of critical transplant drugs that interfere with vitD absorption. We sought to evaluate the safety and efficacy of a single, ultra-high dose of vitD given prior to childhood HSCT to maintain levels in a therapeutic range during the peri-transplantation period...
May 18, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29782691/mass-spectrometry-in-the-palm-of-your-hand-future-applications-of-in-vivo-tissue-analysis
#12
Simon A Fox, Camile S Farah
Assessment and diagnosis of oral mucosal disorders continues to present clinical challenges with conventional methodologies being time consuming and hampered by subjectivity. These considerations also apply to surgical excision of malignant and potentially malignant lesions where accurate assessment of margins is critical to patient outcomes. These clinical needs are driving the development of new technologies which can enable rapid diagnosis based upon characteristic molecular profiles identified through clinical science...
May 21, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29782507/paraclostridium-bifermentans-exacerbates-pathosis-in-a-mouse-model-of-ulcerative-colitis
#13
Ryo Kutsuna, Junko Tomida, Yuji Morita, Yoshiaki Kawamura
Although it has been recognized that intestinal bacteria play an important role in the pathology of human ulcerative colitis (UC), specific pathogenic bacteria for UC have not been identified. We investigated the influence of Paraclostridium bifermentans PAGU1678 strain on the pathology of a UC mouse model and found it increased UC pathosis scores such as loose and bloody stools, reduced diversity of fecal flora, disappearance of the crypt structure of distal colon tissue, destruction of intestinal epithelial cells, and atrophy of the colon...
2018: PloS One
https://www.readbyqxmd.com/read/29782483/magnolol-and-honokiol-attenuate-apoptosis-of-enterotoxigenic-escherichia-coli-induced-intestinal-epithelium-by-maintaining-secretion-and-absorption-homeostasis-and-protecting-mucosal-integrity
#14
Yanli Deng, Xuefeng Han, Shaoxun Tang, Chengjian Li, Wenjun Xiao, Zhiliang Tan
BACKGROUND The cortex of Magnolia officinalis has long been used as an element of traditional Chinese medicine for the treatment of anxiety, chronic bronchitis, and gastrointestinal dysfunction. This study aimed to elucidate the underlying mechanism of its functional ingredients (magnolol and honokiol) in modifying the secretion and absorption homeostasis and protecting mucosal integrity in an Enterotoxigenic Escherichia coli (ETEC)-induced diarrhea mouse model. MATERIAL AND METHODS This study established a diarrhea mouse model infected by ETEC at a dosage of 0...
May 21, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29782417/prevalence-and-analysis-of-medical-device-related-pressure-injuries-results-from-the-international-pressure-ulcer-prevalence-survey
#15
Susan A Kayser, Catherine A VanGilder, Elizabeth A Ayello, Charlie Lachenbruch
OBJECTIVE: To examine the prevalence and characteristics of medical device-related pressure injuries (MDR PIs) in a large, generalizable database. METHODS: This study is a retrospective analysis of the 2016 International Pressure Ulcer Prevalence data. Data were limited to US and Canadian facilities. Facilities included acute care, long-term care, rehabilitation, long-term acute care hospitals, and hospice. Analysis included 102,865 adult patients; 99,876 had complete data and were the focus of the analysis and are reported in the results below...
June 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29782306/urticarial-lesions-in-a-pregnant-woman
#16
Sergio Santos-Alarcón, Cesar Benavente-Villegas, Isabel García-Briz, Magdalena Moneva-Léniz, Celia Sanchis-Sánchez, Almudena Mateu-Puchades
Dear Editor, Gestational pemphigoid (GP) is a rare autoimmune bullous dermatosis in pregnancy. GP usually occurs during the second or third month of pregnancy. It clinically manifests as the development of either early-onset urticarial lesions or late-onset subepidermal blisters that may linger for weeks or even months. Herein we report the case of a 45-year-old woman with the distinctive clinical onset of GP. A forty-five-year-old woman, gravida I, para 0, at 27 weeks gestation, was referred for evaluation to our Department with an extensive pruritic eruption that had developed over the previous 7 days...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#17
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781925/osteo-odonto-keratoprosthesis-in-severe-thermal-and-chemical-injuries
#18
Alfonso Vasquez-Perez, Mehran Zarei-Ghanavati, Venkata Avadhanam, Christopher Liu
PURPOSE: To report the results of osteo-odonto-keratoprosthesis (OOKP) surgery in patients who sustained severe chemical and thermal injuries. METHODS: This is a noncomparative retrospective case series of 14 patients who underwent OOKP surgery between 2001 and 2016 at the Sussex Eye Hospital, Brighton, UK, because of severe chemical and thermal injuries RESULTS:: OOKP surgery was performed in 14 eyes of 14 patients. Eight patients (57%) sustained thermal injuries and 6 patients (43%) chemical injuries...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781755/more-robust-gut-immune-responses-induced-by-combining-intranasal-and-sublingual-routes-for-prime-boost-immunization
#19
Hye Suk Hwang, Sao Puth, Wenzhi Tan, Vivek Verma, Kwangjoon Jeong, Shee Eun Lee, Joon Haeng Rhee
Norovirus causes acute and debilitating gastroenteritis, characterized by vomiting and diarrhea. We recently reported a recombinant GII. 4 P domain particle (Pd) vaccine adjuvanted with a flagellin, Vibrio vulnificus FlaB, effectively promoting both humoral and cell-mediated immune responses. In the previous study, we found that sublingual (SL) immunization induced higher fecal secretory IgA (SIgA) responses while intranasal (IN) route provided higher amplitude of humoral and cellular immune responses in the systemic compartment...
May 21, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29781718/comparsion-of-staining-characteristics-of-toto-bodies
#20
S S Padala, M A Kiresur, A Ananthaneni, V S Guduru, H K Puneeth, B Bhavana
Toto bodies are eosinophilic structures that resemble the cells of the superficial cell layer of the oral epithelium. Toto bodies commonly are associated with inflammatory gingival and other mucosal lesions including pyogenic granuloma, irritational fibroma, epulis fissuratum, peripheral giant cell granuloma and inflammatory hyperplastic gingivitis. We evaluated staining characteristics of Toto bodies to establish their origin and to identify their significance in lesions. We investigated pyogenic granuloma, fibroma and leukoplakia with epithelium that exhibited Toto bodies after hematoxylin and eosin (staining...
May 21, 2018: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
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