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https://www.readbyqxmd.com/read/29468777/caring-for-crying-babies-a-mixed-methods-study-to-understand-factors-influencing-nurses-and-doctors-management-of-infant-colic
#1
James McGann, Jaqueline Manohar, Harriet Hiscock, Denise O'Connor, Jan Hodgson, Franz Babl, Valerie Sung
AIM: The aim of this study was to determine the barriers and enablers influencing the uptake of two recommendations from a tertiary paediatric hospital's clinical practice guidelines by maternal and child health nurses (MCHNs) and emergency department (ED) doctors: (i) explaining normal crying; and (ii) avoiding attributing crying to gastro-oesophageal reflux (GOR) and limiting anti-reflux medication use. METHODS: The study was designed as 1-h focus group discussions, guided by the Theoretical Domains Framework, and a short questionnaire, with a purposive sample of MCHNs and ED doctors in Victoria, Australia in (March to September) 2015...
February 22, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29467124/gastric-and-duodenal-ischaemia-after-transarterial-chemoembolisation-for-hepatocellular-carcinoma-an-unexpected-but-significant-complication
#2
Sai Pavan Chintalapati, Arpan Patel, Hari Conjeevaram
Transarterial chemoembolisation (TACE) is commonly used for unresectable intermediate-stage hepatocellular carcinoma (HCC). TACE is usually well-tolerated. We report a case of a patient who presented with a gastrointestinal bleed from TACE. A 64-year-old man presented with chronic hepatitis C cirrhosis and multifocal bilobar HCC. He had previously undergone multiple TACE sessions, radiofrequency ablation and stereotactic body radiation therapy. In the evening of his TACE procedure, he developed abdominal pain and haematemesis...
February 21, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29465751/prognostic-value-of-pathological-lymph-node-status-and-primary-tumour-regression-grading-following-neoadjuvant-chemotherapy-results-from-the-mrc-oe02-oesophageal-cancer-trial
#3
Nasser Davarzani, Gordon G A Hutchins, Nicholas P West, Lindsay C Hewitt, Mathew Nankivell, David Cunningham, William H Allum, Elizabeth Smyth, Nicola Valeri, Ruth E Langley, Heike I Grabsch
AIMS: Neoadjuvant chemotherapy (NAC) remains an important therapeutic option for advanced oesophageal cancer (OC). Pathological tumour regression grade (TRG) may offer additional information by directing adjuvant treatment and/or follow-up but clinical value remains unclear. We analysed the prognostic value of TRG and associated pathological factors in OC patients enrolled in the Medical Research Council OE02 trial. METHODS: Histopathology was reviewed in 497 resections from OE02 trial participants randomised to surgery (S-group;n=244) or NAC followed by surgery (CS-group;n=253)...
February 21, 2018: Histopathology
https://www.readbyqxmd.com/read/29465746/using-textbook-outcome-as-a-measure-of-quality-of-care-in-oesophagogastric-cancer-surgery
#4
R T van der Kaaij, M V de Rooij, F van Coevorden, F E M Voncken, P Snaebjornsson, H Boot, J W van Sandick
BACKGROUND: Textbook outcome is a multidimensional measure representing an ideal course after oesophagogastric cancer surgery. It comprises ten perioperative quality-of-care parameters and has been developed recently using population-based data. Its association with long-term outcome is unknown. The objectives of this study were to validate the clinical relevance of textbook outcome at a hospital level, and to assess its relation with long-term survival after treatment for oesophagogastric cancer...
February 21, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29462128/mir-146a-5p-mediates-epithelial-mesenchymal-transition-of-oesophageal-squamous-cell-carcinoma-via-targeting-notch2
#5
Cong Wang, Wenxue Zhang, Lin Zhang, Xuan Chen, Fang Liu, Jing Zhang, Shanghui Guan, Yi Sun, Pengxiang Chen, Ding Wang, Effat Un Nesa, Yufeng Cheng, George M Yousef
This corrects the article DOI: 10.1038/bjc.2016.367.
February 20, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29460796/effects-of-goal-directed-fluid-therapy-on-enhanced-postoperative-recovery-an-interventional-comparative-observational-study-with-a-historical-control-group-on-oesophagectomy-combined-with-eras-program
#6
Hideki Taniguchi, Toshio Sasaki, Hisae Fujita, Hiroko Kobayashi, Rieko Kawasaki, Takashi Ogata, Haruhiko Cho, Takaki Yoshikawa, Keiko Ushigome, Akemi Tanaka, Osami Takano
BACKGROUND AND AIMS: The Enhanced Recovery after Surgery (ERAS) program has been proposed as a postoperative recovery-enhancing strategy. We frequently apply the Modified-ERAS program following oesophagectomy. This study aims to elucidate the impact of goal-directed fluid therapy (GDT) for the perioperative management of oesophageal cancer on the postoperative recovery of patients undergoing oesophagectomy. METHODS: This is an interventional before-after comparative observational study conducted at Kanagawa Cancer Centre, Japan...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29460418/reliability-of-histologic-assessment-in-patients-with-eosinophilic-oesophagitis
#7
M J Warners, C A Ambarus, A J Bredenoord, J Verheij, G Y Lauwers, J C Walsh, D A Katzka, S Nelson, T van Viegen, G T Furuta, S K Gupta, L Stitt, G Zou, C E Parker, L M Shackelton, G R D Haens, W J Sandborn, E S Dellon, B G Feagan, M H Collins, V Jairath, R K Pai
BACKGROUND: The validity of the eosinophilic oesophagitis (EoE) histologic scoring system (EoEHSS) has been demonstrated, but only preliminary reliability data exist. AIM: Formally assess the reliability of the EoEHSS and additional histologic features. METHODS: Four expert gastrointestinal pathologists independently reviewed slides from adult patients with EoE (N = 45) twice, in random order, using standardised training materials and scoring conventions for the EoEHSS and additional histologic features agreed upon during a modified Delphi process...
February 20, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29459004/does-gastric-conditioning-decrease-the-incidence-of-cervical-oesophagogastric-anastomotic-leakage
#8
Mónica Miró, Leandre Farran, Fernando Estremiana, Jordi Miquel, Elena Escalante, Humberto Aranda, Carla Bettonica, Maica Galán
INTRODUCTION: Oesophageal reconstruction by gastroplasty with cervical anastomosis has a higher incidence of dehiscence. The aim of the study is to analyse the incidence of anastomotic leakage in patients undergoing gastroplasty with cervical anastomosis following angiographic ischaemic conditioning of the gastric conduit. METHODS: Prospective analysis of patients who underwent gastric conditioning two weeks prior to oesophageal reconstruction, from January 2001 to January 2014...
February 16, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29458786/ecco-essential-requirements-for-quality-cancer-care-oesophageal-and-gastric-cancer
#9
REVIEW
William Allum, Florian Lordick, Maria Alsina, Elisabeth Andritsch, Ahmed Ba-Ssalamah, Marc Beishon, Marco Braga, Carmela Caballero, Fatima Carneiro, Fernando Cassinello, Jan Willem Dekker, Roberto Delgado-Bolton, Karin Haustermans, Geoffrey Henning, Bettina Hutter, József Lövey, Irena Štenglová Netíková, Radka Obermannová, Simon Oberst, Siri Rostoft, Tiina Saarto, Thomas Seufferlein, Sapna Sheth, Venetia Wynter-Blyth, Alberto Costa, Peter Naredi
BACKGROUND: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific type of cancer. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey...
February 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29456774/gastric-aspiration-and-its-role-in-airway-inflammation
#10
REVIEW
E B Hunt, A Sullivan, J Galvin, J MacSharry, D M Murphy
Gastro-Oesophageal Reflux (GOR) has been associated with chronic airway diseases while the passage of foreign matter into airways and lungs through aspiration has the potential to initiate a wide spectrum of pulmonary disorders. The clinical syndrome resulting from such aspiration will depend both on the quantity and nature of the aspirate as well as the individual host response. Aspiration of gastric fluids may cause damage to airway epithelium, not only because acidity is toxic to bronchial epithelial cells but also due to the effect of digestive enzymes such as pepsin and bile salts...
2018: Open Respiratory Medicine Journal
https://www.readbyqxmd.com/read/29455047/prospective-cohort-study-of-neoadjuvant-therapy-toxicity-in-the-treatment-of-oesophageal-adenocarcinoma
#11
David Bunting, Richard Berrisford, Tim Wheatley, Lee Humphreys, Arun Ariyarathenam, Grant Sanders
BACKGROUND: Early studies investigating the benefits of neoadjuvant therapy in oesophageal cancer showed conflicting results, taking many years before a survival advantage was demonstrated in randomised trials. Gains are modest, limited by progressive disease and toxicity. This study aimed to investigate the relationship between neoadjuvant therapy-associated toxicity and clinical outcomes including survival in patients with potentially curable oesophageal adenocarcinoma. MATERIALS AND METHODS: A cohort of 286 patients undergoing neoadjuvant therapy followed by surgical resection at a single institution was identified from a prospective database...
February 15, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29454737/adjuvant-radiotherapy-for-positive-lymph-nodes-of-oesophageal-squamous-cell-carcinoma-can-it-earn-promising-benefits-at-long-term-follow-up
#12
Y Ren, J Ye, W Xiong, J Zuo, Y He, M Tan, Y Yuan
PURPOSE: The value of adjuvant radiotherapy for patients with positive lymph nodes after curative resection of oesophageal squamous cell carcinoma is controversial. This study aims to investigate its long-term benefits in a specific cohort. PATIENTS AND METHODS: The charts between 1990 and 2003 from patients with positive lymph nodes were retrospectively reviewed. Those subjects were divided into adjuvant radiotherapy and surgery alone groups, with two subgroups defined by radiation dose (cutoff value: 50Gy)...
February 14, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29453469/demographic-and-clinical-profile-in-patients-with-liver-cirrhosis-in-a-tertiary-care-hospital-in-central-nepal
#13
Subash Bhattarai, Merina Gyawali, Khus Raj Dewan, Gaurav Shrestha
INTRODUCTION: Liver cirrhosis is an important health problem worldwide and is a common disease in Nepal. The profile of cirrhosis may vary due to different factors. This study was undertaken to see the demographic and clinical profiles of patients with cirrhosis of liver attending a tertiary care hospital in Central Nepal. METHODS: Six hundred patients with clinical features, laboratory and sonological findings suggestive of chronic liver dysfunction and endoscopic evidence of portal hypertension were included in the study...
October 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/29453019/-electrocardiographic-changes-due-to-a-giant-para-oesophageal-hernia
#14
L España Fuente, L J Fernández Sánchez
No abstract text is available yet for this article.
February 13, 2018: Semergen
https://www.readbyqxmd.com/read/29449956/bilateral-bronchial-stent-deployment-for-palliative-treatment-of-a-compressive-intrathoracic-mass-in-a-cat
#15
Kieran Borgeat, Kerry Simpson, David Reese, Helen Wilson, Joanna Potter, Daniel Ogden
Case summary: Bronchial stents may be useful to relieve clinical signs of extraluminal compression. Herein we describe a case which, to our knowledge, is the first cat where bilateral bronchial stents have been used clinically. Respiratory signs of principal bronchial compression were alleviated after the stent procedure. Minor complications occurred, specifically: severe hypoxia during stent deployment; a transient, self-limiting postoperative pneumothorax possibly associated with ventilation-induced lung injury; bronchopneumonia (possibly pre-existing); and transient worsening of cough postoperatively...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29447881/tympanostomy-tubes-for-serous-otitis-media-and-risk-of-recurrences
#16
Nathalie Klopp-Dutote, Catherine Kolski, Vladimir Strunski, Cyril Page
OBJECTIVES: To determine the value of tympanostomy tubes (TTs) in the management of serous otitis media (SOM) and the risk factors for SOM recurrence. METHOD: This single-centre cohort study was performed in the University hospital of Amiens, France; and concerned 215 under-12 children having undergone at least one bilateral TT (Shepard grommet-type) placements for SOM. RESULTS: The mean TT retention time was 10 months. SOM recurred in 79 children (62...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446982/development-of-an-omentum-cultured-oesophageal-scaffold-reinforced-by-a-3d-printed-ring-feasibility-of-an-in-vivo-bioreactor
#17
Eun-Jae Chung, Hyung Woo Ju, Yeung Kyu Yeon, Ji Seung Lee, Young Jin Lee, Ye Been Seo, Park Chan Hum
Current treatments of oesophageal diseases, such as carcinoma, congenital abnormality or trauma, require surgical intervention and oesophageal reconstruction with the stomach, jejunum or colon. However, serious side effects are possible with each treatment option. Despite tissue engineering promising to be an effective regenerative strategy, no functional solution currently exists for oesophageal reconstruction. Here, we developed an omentum-cultured oesophageal scaffold reinforced by a 3D-printed ring. The nano-structured scaffolds were wrapped into the omentum of rats and orthotopically transplanted for the repair of circumferential oesophageal defects two weeks later...
February 15, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29439009/her2-testing-of-gastro-oesophageal-adenocarcinoma-a-commentary-and-guidance-document-from-the-association-of-clinical-pathologists-molecular-pathology-and-diagnostics-committee
#18
REVIEW
Newton A C S Wong, Fernanda Amary, Rachel Butler, Richard Byers, David Gonzalez, Harry R Haynes, Mohammad Ilyas, Manuel Salto-Tellez, Philippe Taniere
The use of biologics targeted to the human epidermal growth factor receptor 2 (HER2) protein is the latest addition to the armamentarium used to fight advanced gastric or gastro-oesophageal junction adenocarcinoma. The decision to treat with the biologic trastuzumab is completely dependent on HER2 testing of tumour tissue. In 2017, the College of American Pathologists, American Society for Clinical Pathology and the American Society of Clinical Oncology jointly published guidelines for HER2 testing and clinical decision making in gastro-oesophageal adenocarcinoma...
February 8, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29437910/modern-diagnosis-of-gerd-the-lyon-consensus
#19
REVIEW
C Prakash Gyawali, Peter J Kahrilas, Edoardo Savarino, Frank Zerbib, Francois Mion, André J P M Smout, Michael Vaezi, Daniel Sifrim, Mark R Fox, Marcelo F Vela, Radu Tutuian, Jan Tack, Albert J Bredenoord, John Pandolfino, Sabine Roman
Clinical history, questionnaire data and response to antisecretory therapy are insufficient to make a conclusive diagnosis of GERD in isolation, but are of value in determining need for further investigation. Conclusive evidence for reflux on oesophageal testing include advanced grade erosive oesophagitis (LA grades C and D), long-segment Barrett's mucosa or peptic strictures on endoscopy or distal oesophageal acid exposure time (AET) >6% on ambulatory pH or pH-impedance monitoring. A normal endoscopy does not exclude GERD, but provides supportive evidence refuting GERD in conjunction with distal AET <4% and <40 reflux episodes on pH-impedance monitoring off proton pump inhibitors...
February 3, 2018: Gut
https://www.readbyqxmd.com/read/29437560/drinking-very-hot-tea-linked-to-oesophageal-cancer
#20
Jacqui Wise
No abstract text is available yet for this article.
February 5, 2018: BMJ: British Medical Journal
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