Daniel Silva Dias, Juliana Martins Machado, Patrícia Aparecida Fernandes Ribeiro, Amanda Sanchez Machado, Fernanda Fonseca Ramos, Lais Moreira Nogueira, Ana Alice Maia Gonçalves, Luana de Sousa Ramos, Isadora Braga Gandra, Flaviane Silva Coutinho, Michelli Dos Santos, Jonatas Oliveira da Silva, Miguel Angel Chávez-Fumagalli, Rafael Gonçalves Teixeira-Neto, Ana Thereza Chaves, Mariana Campos-da-Paz, Amanda A Souza, Rodolfo Cordeiro Giunchetti, Sonia Maria Freitas, Sandra Lyon, Danielle Ferreira de Magalhães-Soares, Julia Angelica Gonçalves Silveira, Eduardo Sergio Silva, Eduardo Antonio Ferraz Coelho, Alexsandro Sobreira Galdino
BACKGROUND: visceral leishmaniasis (VL) is a critical public health problem in over ninety countries. The control measures adopted in Brazil have been insufficient when it comes to preventing the spread of this overlooked disease. In this context, a precise diagnosis of VL in dogs and humans could help to reduce the number of cases of this disease. Distinct studies for the diagnosis of VL have used single recombinant proteins in serological assays; however, the results have been variable, mainly in relation to the sensitivity of the antigens...
February 11, 2023: Pathogens