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Hydroxycloroquine

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https://www.readbyqxmd.com/read/25500706/coxiella-burnetii-infection-in-hemodialysis-and-other-vascular-grafts
#1
Marcela González-Del Vecchio, Antonio Vena, Maricela Valerio, Mercedes Marin, Eduardo Verde, Patricia Muñóz, Emilio Bouza
Prosthetic arteriovenous (AV) graft infection is the principal cause of morbidity related to chronic hemodialysis AV graft fistula. Coxiella burnetii is a known pathogen that causes fever, pneumonia, and intravascular infections with the limitation of negative cultures. Herein, we report the first case of a patient who presented to the emergency department of our hospital with a prosthetic hemodialysis AV graft infection due to Coxiella burnetii. We also performed a literature search with PubMed to identify studies reporting cases of Coxiella burnetii vascular graft infection...
November 2014: Medicine (Baltimore)
https://www.readbyqxmd.com/read/24004900/two-anthrax-cases-with-soft-tissue-infection-severe-oedema-and-sepsis-in-danish-heroin-users
#2
Lene Russell, Michael Pedersen, Andreas V Jensen, Lillian Marie Søes, Ann-Brit Eg Hansen
BACKGROUND: Anthrax had become extremely rare in Europe, but in 2010 an outbreak of anthrax among heroin users in Scotland increased awareness of contaminated heroin as a source of anthrax. We present the first two Danish cases of injectional anthrax and discuss the clinical presentations, which included both typical and more unusual manifestations. CASE PRESENTATIONS: The first patient, a 55-year old man with HIV and hepatitis C virus co-infection, presented with severe pain in the right thigh and lower abdomen after injecting heroin into the right groin...
2013: BMC Infectious Diseases
https://www.readbyqxmd.com/read/22751197/hydroxycloroquine-induced-oxidative-stress-on-sciatic-nerve-and-muscle-tissue-of-rats-a-stereological-and-biochemical-study
#3
E Uzar, R Ozay, O Evliyaoglu, A Aktas, M B Ulkay, M E Uyar, A Ersoy, A Z Burakgazi, C Turkay, A Ilhan
The aim of this study was to investigate the role of hydroxychloroquine (HCQ)-induced oxidative stress on sciatic nerve and muscle tissues of rats. The oxidant/antioxidant parameters in the sciatic nerve and muscle tissues were analyzed, and stereological analysis of the sciatic nerve was performed. Levels of malondialdehyde and nitric oxide in the tissues were significantly higher in the HCQ group than in the control group (p < 0.05). In addition, activities of superoxide dismutase and glutathione peroxidase were found to be significantly higher in the HCQ group than the control group (p < 0...
October 2012: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/17711896/lupus-in-adolescence
#4
REVIEW
I Kone-Paut, M Piram, S Guillaume, T A Tran
Juvenile systemic lupus erythematosus (JSLE) represents 15-20% of all SLE cases. The leading presenting symptoms of JSLE are constitutional and not specific such as fatigue, headache, weight loss or mood swings. They are also encountered in healthy adolescents, which explains frequent diagnosis delay. The frequency of irreversible damage is high in JSLE and involves especially the renal, musculoskeletal and neuropsychiatric systems. Although the overall prognosis has markedly improved, thanks to earlier diagnosis and new therapeutic approaches, cardiovascular, hematological events and chronic renal failure remain severe, and constitute the main disease-related causes of death...
2007: Lupus
https://www.readbyqxmd.com/read/16075133/-rituximab-anti-cd20-monoclonal-antibody-for-refractory-systemic-lupus-erythematosus-report-of-one-case
#5
Francisca Sabugo, Carolina Llanos, Lilian Soto, Jorge Gutiérrez, Miguel Cuchacovich
New therapeutic approaches that include depletion of B cells using rituximab, a chimeric monoclonal antibody directed against the B cell specific antigen CD-20 have been developed for the treatment of systemic lupus erythematosus (SLE). We report the case of a 18 years old girl with SLE that did not respond and experienced adverse effects with the use of hydroxycloroquine, methotrexate, mycophenolate mofetil, azathioprine and high-dose steroids. Rituximab was given weekly at 375 mg/m(2) for four doses. The drug was well tolerated and the patient had no adverse reactions...
June 2005: Revista Médica de Chile
https://www.readbyqxmd.com/read/12563365/-hepatitis-c-virus-infection-and-arthritis-a-clinico-serological-investigation-of-arthritis-in-patients-with-or-without-cryoglobulinemic-syndrome
#6
P Fadda, L La Civita, A L Zignego, C Ferri
OBJECTIVE: To compare the clinico-serological features of arthritis from two HCV+ patient groups characterized by mixed cryoglobulinemia (MC) or chronic hepatitis (CH). METHODS: We retrospectively studied 157 MC patients (119 females, mean age 64.8 yrs, range 36-88) and 155 CH patients (103 females, mean age 58.8 yrs, range 30-81). Patients with HBV and/or HIV co-infections and a follow-up shorter than 1 year were excluded. MC was classified according to standard criteria, while CH classification was based on Desmet's criteria...
October 2002: Reumatismo
https://www.readbyqxmd.com/read/9549387/-combined-drug-therapy-in-recent-onset-rheumatoid-arthritis-evaluation-after-1-year-of-treatment
#7
COMPARATIVE STUDY
D Biasi, P Caramaschi, A Carletto, M L Pacor, S Zeminian, L M Bambara
The aim of our study is to evaluate the efficacy and safety of a combination therapy with hydroxycloroquine, gold sodium thiomalate and methotrexate in patients affected by recent onset active rheumatoid arthritis. Twenty-five patients (6 men e 19 women, average age 46.2 +/- 12.2) were enrolled in this study and 18 of them have been treated for 1 year with the three above-mentioned drugs at optimal doses. Drug toxicity was carefully monitored. Clinical and hematochemical parameters of efficacy were evaluated every three months...
January 1998: Recenti Progressi in Medicina
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