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https://www.readbyqxmd.com/read/27918573/benchmarking-the-cost-per-person-of-mass-treatment-for-selected-neglected-tropical-diseases-an-approach-based-on-literature-review-and-meta-regression-with-web-based-software-application
#1
Christopher Fitzpatrick, Fiona M Fleming, Matthew Madin-Warburton, Timm Schneider, Filip Meheus, Kingsley Asiedu, Anthony W Solomon, Antonio Montresor, Gautam Biswas
BACKGROUND: Advocacy around mass treatment for the elimination of selected Neglected Tropical Diseases (NTDs) has typically put the cost per person treated at less than US$ 0.50. Whilst useful for advocacy, the focus on a single number misrepresents the complexity of delivering "free" donated medicines to about a billion people across the world. We perform a literature review and meta-regression of the cost per person per round of mass treatment against NTDs. We develop a web-based software application (https://healthy...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27918248/prevalence-of-trachoma-in-benishangul-gumuz-region-ethiopia-results-of-seven-population-based-surveys-from-the-global-trachoma-mapping-project
#2
Yilikal Adamu, Colin Macleod, Liknaw Adamu, Wirtu Fikru, Beyene Kidu, Aida Abashawl, Michael Dejene, Brian K Chu, Rebecca M Flueckiger, Rebecca Willis, Alexandre L Pavluck, Anthony W Solomon
PURPOSE: Trachoma is a major cause of blindness in Ethiopia, and targeted for elimination as a public health problem by the year 2020. Prevalence data are needed to plan interventions. We set out to estimate the prevalence of trachoma in each evaluation unit of grouped districts ("woredas") in Benishangul Gumuz region, Ethiopia. METHODS: We conducted seven cross-sectional community-based surveys, covering 20 woredas, between December 2013 and January 2014, as part of the Global Trachoma Mapping Project (GTMP)...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918232/the-prevalence-of-trachoma-in-tigray-region-northern-ethiopia-results-of-11-population-based-prevalence-surveys-completed-as-part-of-the-global-trachoma-mapping-project
#3
Sadik Taju Sherief, Colin Macleod, Goitum Gigar, Hagos Godefay, Atakelit Abraha, Michael Dejene, Amir B Kello, Aberash Belete, Yitbarek Assefa, Rebecca Willis, Brian K Chu, Anthony W Solomon
PURPOSE: We aimed to estimate the prevalence of trachoma in each district ("woreda") of Tigray Region, Ethiopia. METHODS: We conducted 11 cross-sectional community-based surveys in evaluation units covering 34 rural woredas from January to March 2013 using the standardized methodology developed for the Global Trachoma Mapping Project. RESULTS: Teams visited 8034 households in 275 villages. A total of 28,581 consenting individuals were examined, 16,163 (56...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918229/prevalence-of-and-risk-factors-for-trachoma-in-southern-nations-nationalities-and-peoples-region-ethiopia-results-of-40-population-based-prevalence-surveys-carried-out-with-the-global-trachoma-mapping-project
#4
Tesfaye Haileselassie Adera, Colin Macleod, Misganu Endriyas, Michael Dejene, Rebecca Willis, Brian K Chu, Yohannes Letamo, Tebeje Misganaw, Tamiru Mesele, Emebet Mekonnen, Alemayehu Sisay, Yeneneh Mulugeta, Wondu Alemayehu, Khumbo Kalua, Tezera Kifle Destu, Yilikal Adamu, Jennifer L Smith, Abu Beyene, Addisu Tadesse, Anthony W Solomon
PURPOSE: We sought to estimate the prevalence of trachoma at sufficiently fine resolution to allow elimination interventions to begin, where required, in the Southern Nations, Nationalities, and Peoples' Region (SNNPR) of Ethiopia. METHODS: We carried out cross-sectional population-based surveys in 14 rural zones. A 2-stage cluster randomized sampling technique was used. A total of 40 evaluation units (EUs) covering 110 districts ("woredas") were surveyed from February 2013 to May 2014 as part of the Global Trachoma Mapping Project (GTMP), using the standardized GTMP training package and methodology...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918227/mapping-trachoma-in-kaduna-state-nigeria-results-of-23-local-government-area-level-population-based-prevalence-surveys
#5
Nasiru Muhammad, Caleb Mpyet, Mohammed Dantani Adamu, Adamani William, Murtala Muhammad Umar, Musa Goyol, Habila Muazu, Uwaezuoke Onyebuchi, Sunday Isiyaku, Rebecca M Flueckiger, Brian K Chu, Rebecca Willis, Alexandre L Pavluck, Abdullahi Alhassan, Nicholas Olobio, Bruce A Gordon, Anthony W Solomon
INTRODUCTION: To prepare for global elimination of trachoma by 2020, the World Health Organization (WHO) recommends mapping of trachoma at district-level to enable planning of elimination activities in affected populations. The aim of our study was to provide data on trachoma for each local government area (LGA) of Kaduna State, Nigeria, as such data were previously unavailable. METHOD: As part of the Global Trachoma Mapping Project (GTMP), a population-based cross-sectional trachoma survey was conducted in each of the 23 LGAs of Kaduna State, between May and June 2013...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918223/prevalence-of-trachoma-in-niger-state-north-central-nigeria-results-of-25-population-based-prevalence-surveys-carried-out-with-the-global-trachoma-mapping-project
#6
Mohammed Dantani Adamu, Caleb Mpyet, Nasiru Muhammad, Murtala Muhammad Umar, Habila Muazu, Francisca Olamiju, Sunday Isiyaku, Uwazoeke Onyebuchi, Usman Abubakar Bosso, Adamani William, Benjamin C Nwobi, Rebecca Willis, Rebecca Mann Flueckiger, Alexandre Pavluck, Brian K Chu, Nicholas Olobio, Anthony W Solomon
PURPOSE: To determine the prevalence of trachoma in each of the 25 local government areas (LGAs) of Niger State, Nigeria. METHODS: A population-based cross-sectional survey was conducted in each Niger State LGA between March and April 2014, as part of the Global Trachoma Mapping Project (GTMP). GTMP protocols were used in planning and conduct of the surveys. Using probability proportional to size, 25 clusters were selected; in each of these clusters, 25 households were enrolled for the survey...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27918222/prevalence-of-trachoma-in-gambella-region-ethiopia-results-of-three-population-based-prevalence-surveys-conducted-with-the-global-trachoma-mapping-project
#7
Aida Abashawl, Colin Macleod, John Riang, Ferede Mossisa, Michael Dejene, Rebecca Willis, Rebecca M Flueckiger, Alexandre L Pavluck, Addisu Tadesse, Tesfaye Haileselassie Adera, Anthony W Solomon
PURPOSE: In Ethiopia, trachoma is a major public health problem, accounting for 11.5% of all cases of blindness. In Gambella, one of the country's most remote regions, the 2005-2006 National Survey of Blindness, Low Vision and Trachoma estimated a region-level prevalence of active trachoma of 19.1% in those aged 1-9 years. Detailed district or sub-regional level estimates are required to implement interventions. METHODS: Population-based prevalence surveys were carried out following a 2-stage cluster random sampling methodology and Global Trachoma Mapping Project protocols...
December 5, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27893297/population-based-trachoma-mapping-in-six-evaluation-units-of-papua-new-guinea
#8
Robert Ko, Colin Macleod, David Pahau, Oliver Sokana, Drew Keys, Anthea Burnett, Rebecca Willis, Geoffrey Wabulembo, Jambi Garap, Anthony W Solomon
PURPOSE: We sought to determine the prevalence of trachomatous inflammation - follicular (TF) in children aged 1-9 years, and trachomatous trichiasis (TT) in those aged ≥15 years, in suspected trachoma-endemic areas of Papua New Guinea (PNG). METHODS: We carried out six population-based prevalence surveys using the protocol developed as part of the Global Trachoma Mapping Project. RESULTS: A total of 19,013 individuals were sampled for inclusion, with 15,641 (82...
November 28, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27865692/elimination-of-blinding-trachoma-in-china
#9
T Liu, Q Liang, A Hu, G Feng, N Wang, X Peng, C Baudouin, A Labbé
OBJECTIVE: To present the change in the prevalence of blindness caused by trachoma between 1987 and 2006 by secondary data analysis based on two China National Sample Surveys on Disability (CNSSD). METHODS: Secondary data analysis was performed on two China National Sample Surveys on Disability (CNSSD), which were national representative household surveys conducted in 1987 and 2006. The prevalence of blindness caused by trachoma was estimated by 10-year age group...
November 16, 2016: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/27852877/community-seroprevalence-survey-for-yaws-and-trachoma-in-the-western-division-of-fiji
#10
Naomi Cocks, Merelesita Rainima-Qaniuci, Chelsea Yalen, Colin Macleod, Apisalome Nakolinivalu, Stephanie Migchelsen, Chrissy H Roberts, Robert Butcher, Mike Kama, David Mabey, Michael Marks
INTRODUCTION: Both yaws and trachoma are endemic in several countries in the Pacific. In co-endemic countries there may be potential synergies between both control programmes. METHODS: We undertook a cluster randomised trachoma and yaws seroprevalence survey of children in the Western Division of Fiji. Children were examined for skin lesions consistent with active yaws. A dried blood spot was collected which was tested using the Treponema pallidum particle agglutination (TPPA) test and an ELISA to detect antibodies against Pgp3...
November 16, 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27846369/prevalence-of-trachoma-in-bauchi-state-nigeria-results-of-20-local-government-area-level-surveys
#11
Caleb Mpyet, Nasiru Muhammad, Mohammed Dantani Adamu, Habila Muazu, Murtala Muhammad Umar, Mohammed Abdull, Joel Alada, Musa Goyol, Uwaezuoke Onyebuchi, Francisca Olamiju, Sunday Isiyaku, Adamani William, Benjamin C Nwobi, Rebecca Willis, Rebecca Mann Flueckiger, Alex Pavluck, Brian K Chu, Nicholas Olobio, Anthony W Solomon
PURPOSE: To determine the prevalence of trachomatous inflammation - follicular (TF) and trichiasis in each of the 20 local government areas (LGAs) of Bauchi State, Nigeria. METHODS: We undertook a population-based prevalence survey in each LGA in Bauchi State, employing the Global Trachoma Mapping Project methodology. We used a 2-stage, systematic and quasi-random sampling strategy. Using probability proportional to size, we selected 25 clusters, in each of which 25 households were selected by random walk...
November 15, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27846362/national-trachoma-assessment-in-the-lao-people-s-democratic-republic-in-2013-2014
#12
Khamphoua Southisombath, Siphet Sisalermsak, Phonesavanh Chansan, Khongsap Akkhavong, Soulasay Phommala, Susan Lewallen, Paul Courtright, Anthony W Solomon
PURPOSE: Population-based prevalence surveys were undertaken to determine whether trachoma is a public health problem in Laos requiring implementation of the SAFE strategy (surgery, antibiotics, facial cleanliness, environmental improvement). METHODS: The country was divided into 19 evaluation units (EUs), each containing a population of roughly 100,000-350,000 people. Of these, 16 were believed most likely to harbor trachoma (based on historical evidence), and were mapped using the Global Trachoma Mapping Project methods...
November 15, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27830198/trachoma-past-present-and-future
#13
REVIEW
Mehrdad Mohammadpour, Mojtaba Abrishami, Ahmad Masoumi, Hassan Hashemi
PURPOSE: To review the background, epidemiology and current management of trachoma in endemic areas and worldwide. METHODS: Review of literature. RESULTS: Trachoma is one of the leading causes of preventable blindness in developing countries. It was reported as one of the seven most neglected tropical diseases that can be prevented via drug administration. Its infliction is primarily aimed at those living in areas deprived of clean water and proper sanitation...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27824506/prevalence-of-trachoma-in-schoolchildren-in-brazil
#14
Expedito José de Albuquerque Luna, Maria de Fátima Costa Lopes, Norma Helen Medina, Joana Favacho, Maria Regina Alves Cardoso
PURPOSE: Trachoma was hyperendemic in Brazil until the 20th century. The prevalence has declined sharply in the past decades. The aim of this study was to estimate trachoma prevalence in schoolchildren in Brazilian municipalities with a Human Development Index (HDI) below the national mean. METHODS: A cluster random sampling survey on trachoma prevalence was carried out. Brazilian municipalities with HDI below the national mean, within each of the 27 states, were stratified into three strata according to population size...
November 8, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27820670/surveillance-and-azithromycin-treatment-for-newcomers-and-travelers-evaluation-asante-trial-design-and-baseline-characteristics
#15
Ann-Margret Ervin, Harran Mkocha, Beatriz Munoz, Kurt Dreger, Laura Dize, Charlotte Gaydos, Thomas C Quinn, Sheila K West
PURPOSE: Immigrants and travelers may be sources of re-emergent infection in trachoma-endemic communities close to trachoma elimination. The primary objective of the A Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) trial was to determine whether a newcomer and traveler surveillance and treatment program in addition to annual mass drug administration (MDA) would reduce Chlamydia trachomatis infection when compared to MDA alone. METHODS: ASANTE was a randomized controlled trial in 52 communities in Kongwa, Tanzania...
December 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27820657/prevalence-of-and-risk-factors-for-trachoma-in-oromia-regional-state-of-ethiopia-results-of-79-population-based-prevalence-surveys-conducted-with-the-global-trachoma-mapping-project
#16
Berhanu Bero, Colin Macleod, Wondu Alemayehu, Solomon Gadisa, Ahmed Abajobir, Yilikal Adamu, Menbere Alemu, Liknaw Adamu, Michael Dejene, Addis Mekasha, Zelalem Habtamu Jemal, Damtew Yadeta, Oumer Shafi, Genet Kiflu, Rebecca Willis, Rebecca M Flueckiger, Brian K Chu, Alexandre L Pavluck, Anthony W Solomon
PURPOSE: To complete the baseline trachoma map in Oromia, Ethiopia, by determining prevalences of trichiasis and trachomatous inflammation - follicular (TF) at evaluation unit (EU) level, covering all districts (woredas) without current prevalence data or active control programs, and to identify factors associated with disease. METHODS: Using standardized methodologies and training developed for the Global Trachoma Mapping Project, we conducted cross-sectional community-based surveys from December 2012 to July 2014...
November 7, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27788186/-if-an-eye-is-washed-properly-it-means-it-would-see-clearly-a-mixed-methods-study-of-face-washing-knowledge-attitudes-and-behaviors-in-rural-ethiopia
#17
Kristen Aiemjoy, Nicole E Stoller, Sintayehu Gebresillasie, Ayalew Shiferaw, Zerihun Tadesse, Tegene Sewnet, Bezuayehu Ayele, Melsew Chanyalew, Kelly Callahan, Aisha Stewart, Paul M Emerson, Thomas M Lietman, Jeremy D Keenan, Catherine E Oldenburg
BACKGROUND: Face cleanliness is a core component of the SAFE (Surgery, Antibiotics, Facial cleanliness, and Environmental improvements) strategy for trachoma control. Understanding knowledge, attitudes, and behaviors related to face washing may be helpful for designing effective interventions for improving facial cleanliness. METHODS: In April 2014, a mixed methods study including focus groups and a quantitative cross-sectional study was conducted in the East Gojjam zone of the Amhara region of Ethiopia...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27783678/the-relationship-between-active-trachoma-and-ocular-chlamydia-trachomatis-infection-before-and-after-mass-antibiotic-treatment
#18
Athumani M Ramadhani, Tamsyn Derrick, David Macleod, Martin J Holland, Matthew J Burton
BACKGROUND: Trachoma is a blinding disease, initiated in early childhood by repeated conjunctival infection with the obligate intracellular bacterium Chlamydia trachomatis. The population prevalence of the clinical signs of active trachoma; ''follicular conjunctivitis" (TF) and/or ''intense papillary inflammation" (TI), guide programmatic decisions regarding the initiation and cessation of mass drug administration (MDA). However, the persistence of TF following resolution of infection at both the individual and population level raises concerns over the suitability of this clinical sign as a marker for C...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27775463/prevalence-of-trachoma-in-katsina-state-nigeria-results-of-34-district-level-surveys
#19
Caleb Mpyet, Nasiru Muhammad, Mohammed Dantani Adamu, Habila Muazu, Murtala Mohammad Umar, Musa Goyol, Uwazoeke Onyebuchi, Ima Chima, Haliru Idris, Adamani William, Sunday Isiyaku, Benjamin Nwobi, Rebecca Mann Flueckiger, Rebecca Willis, Alexandre Pavluck, Brian K Chu, Nicholas Olobio, Anthony W Solomon
PURPOSE: To determine the local government area (LGA)-level prevalence of trachoma in all 34 LGAs of Katsina State. METHODS: A population-based prevalence survey was conducted in each LGA of Katsina State, using the Global Trachoma Mapping Project methodology. We used a 3-stage cluster random sampling strategy to select 25 households from each of 25 clusters. We examined all residents of selected households aged 1 year and older for the clinical signs of trachomatous inflammation-follicular (TF), trachomatous inflammation-intense and trichiasis, using the World Health Organization (WHO) simplified grading scheme...
October 24, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27775455/progress-of-trachoma-mapping-in-mainland-tanzania-results-of-baseline-surveys-from-2012-to-2014
#20
Upendo J Mwingira, George Kabona, Mathias Kamugisha, Edward Kirumbi, Bernard Kilembe, Alistidia Simon, Andreas Nshala, Deogratias Damas, Alphonsina Nanai, Mwelecele Malecela, Maria Chikawe, Christina Mbise, Harran Mkocha, Patrick Massae, Humphrey R Mkali, Lisa Rotondo, Kathryn Crowley, Rebecca Willis, Anthony W Solomon, Jeremiah M Ngondi
PURPOSE: Following surveys in 2004-2006 in 50 high-risk districts of mainland Tanzania, trachoma was still suspected to be widespread elsewhere. We report on baseline surveys undertaken from 2012 to 2014. METHODS: A total of 31 districts were surveyed. In 2012 and 2013, 12 at-risk districts were selected based on proximity to known trachoma endemic districts, while in 2014, trachoma rapid assessments were undertaken, and 19 of 55 districts prioritized for baseline surveys...
October 24, 2016: Ophthalmic Epidemiology
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