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https://www.readbyqxmd.com/read/28087393/william-glenn-surgeon-scientist-and-leader-of-new-england-surgery
#1
Andrew Cw Baldwin, John C Baldwin, Walter E Longo
No abstract text is available yet for this article.
January 10, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28087118/open-lower-limb-fractures-in-major-trauma-centers-a-loss-leader
#2
Elizabeth K Tissingh, Arman Memarzadeh, Joseph Queally, Peter Hull
PURPOSE: Open lower limb fractures are resource intensive injuries. Regardless of the financing model, the cost of treatment is an important consideration for any healthcare provider. METHODS: Open lower limb fractures treated at our centre were identified over a six-month period. Isolated open femur or tibia fractures were included as well as cases with multiple fractures. Direct inpatient care costs were calculated and income was reviewed for each case according to 'Healthcare Resource Group' (HRG) cost codes...
December 28, 2016: Injury
https://www.readbyqxmd.com/read/28086857/evaluating-a-multicomponent-social-behaviour-change-communication-strategy-to-reduce-intimate-partner-violence-among-married-couples-study-protocol-for-a-cluster-randomized-trial-in-nepal
#3
Cari Jo Clark, Rachael A Spencer, Binita Shrestha, Gemma Ferguson, J Michael Oakes, Jhumka Gupta
BACKGROUND: Intimate partner violence (IPV) is a significant public health issue that affects 1 in 3 women globally and a similarly large number of women in Nepal. Over the past decade, important policy and programmatic steps have been taken to address violence against women in Nepal. There remains a dearth of evidence on the effectiveness of primary violence prevention strategies. The Change Starts at Home study begins to fill this gap by utilizing a multi-component social behaviour change communication (SBCC) strategy involving a radio drama and community mobilization to shift attitudes, norms and behaviours that underpin IPV perpetration in Nepal...
January 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28086816/rationale-description-and-baseline-findings-of-a-community-based-prospective-cohort-study-of-kidney-function-amongst-the-young-rural-population-of-northwest-nicaragua
#4
Marvin González-Quiroz, Armando Camacho, Dorien Faber, Aurora Aragón, Catharina Wesseling, Jason Glaser, Jennifer Le Blond, Liam Smeeth, Dorothea Nitsch, Neil Pearce, Ben Caplin
BACKGROUND: An epidemic of Mesoamerican Nephropathy (MeN) is killing thousands of agricultural workers along the Pacific coast of Central America, but the natural history and aetiology of the disease remain poorly understood. We have recently commenced a community-based longitudinal study to investigate Chronic Kidney Disease (CKD) in Nicaragua. Although logistically challenging, study designs of this type have the potential to provide important insights that other study designs cannot...
January 13, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28086813/information-exchange-networks-of-health-care-providers-and-evidence-based-cardiovascular-risk-management-an-observational-study
#5
Naomi Heijmans, Jan van Lieshout, Michel Wensing
BACKGROUND: Although a wide range of preventive and clinical interventions has targeted cardiovascular risk management (CVRM), outcomes remain suboptimal. Therefore, the question is what additional determinants of CVRM and outcomes can be identified and addressed to optimize CVRM. In this study, we aimed to identify new perspectives for improving healthcare delivery and explored associations between information exchange networks of health care providers and evidence-based CVRM. METHODS: This observational study was performed parallel to a randomized clinical trial which aimed to improve professional performance of practice nurses in the Netherlands...
January 13, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28081126/a-pan-lyssavirus-taqman-real-time-rt-pcr-assay-for-the-detection-of-highly-variable-rabies-virus-and-other-lyssaviruses
#6
Ashutosh Wadhwa, Kimberly Wilkins, Jinxin Gao, Rene Edgar Condori Condori, Crystal M Gigante, Hui Zhao, Xiaoyue Ma, James A Ellison, Lauren Greenberg, Andres Velasco-Villa, Lillian Orciari, Yu Li
Rabies, resulting from infection by Rabies virus (RABV) and related lyssaviruses, is one of the most deadly zoonotic diseases and is responsible for up to 70,000 estimated human deaths worldwide each year. Rapid and accurate laboratory diagnosis of rabies is essential for timely administration of post-exposure prophylaxis in humans and control of the disease in animals. Currently, only the direct fluorescent antibody (DFA) test is recommended for routine rabies diagnosis. Reverse-transcription polymerase chain reaction (RT-PCR) based diagnostic methods have been widely adapted for the diagnosis of other viral pathogens, but there is currently no widely accepted rapid real-time RT-PCR assay for the detection of all lyssaviruses...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28079597/histologic-findings-of-severe-therapy-resistant-asthma-from-video-assisted-thoracoscopic-surgery-biopsies
#7
Humberto E Trejo Bittar, Daniel Doberer, Mitra Mehrad, Diane C Strollo, Joseph K Leader, Sally Wenzel, Samuel A Yousem
The histologic changes occurring in severe/therapy-resistant asthma (SA) as defined by the European Respiratory Society/American Thoracic Society guidelines, particularly at the level of the distal airways are unknown. This study describes the clinical, radiologic, and histologic characteristics of 29 SA patients who underwent video-assisted thoracoscopic surgery lung biopsy. Pathologic observations were correlated with clinical features, especially the presence of autoimmune disease (AID) (15/29, 51.7%). Ten biopsies (10/29, 34...
February 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28078745/the-effect-of-structural-empowerment-of-nurses-on-quality-outcomes-in-hospitals-a-scoping-review
#8
Nicole S Goedhart, Catharina J van Oostveen, Hester Vermeulen
AIM: To assess and synthesise studies reporting direct associations between the structural empowerment of frontline nurses and quality outcomes, and to identify gaps in the current literature. BACKGROUND: The empowerment of nurses seems essential for delivering high-quality patient care. Understanding the relationship between empowerment and quality outcomes would enable nurse managers to make informed choices on improving the quality of care. METHODS: A scoping review examining the relationship between the structural empowerment of nurses and the quality, effectiveness, safety, efficiency and patient-centredness of care in hospitals...
January 11, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28078667/philanthropy-in-health-professions-education-research-determinants-of-success
#9
Robert Paul, Elisa Hollenberg, Brian D Hodges
CONTEXT: Fund-raising is a new practice in medical education research. OBJECTIVES: This qualitative study explores a cross-sectional analysis of philanthropy in medical education in Canada and Europe and identifies some common characteristics in the fund-raising system, key roles and characteristics of research sites that have had success. METHODS: Medical education research sites that had received donations greater than Can$100 000 were identified by searching publicly available sources...
January 11, 2017: Medical Education
https://www.readbyqxmd.com/read/28077148/linking-communities-to-formal-health-care-providers-through-village-health-teams-in-rural-uganda-lessons-from-linking-social-capital
#10
Laban Kashaija Musinguzi, Emmanueil Benon Turinawe, Jude T Rwemisisi, Daniel H de Vries, David K Mafigiri, Denis Muhangi, Marije de Groot, Achilles Katamba, Robert Pool
BACKGROUND: Community-based programmes, particularly community health workers (CHWs), have been portrayed as a cost-effective alternative to the shortage of health workers in low-income countries. Usually, literature emphasises how easily CHWs link and connect communities to formal health care services. There is little evidence in Uganda to support or dispute such claims. Drawing from linking social capital framework, this paper examines the claim that village health teams (VHTs), as an example of CHWs, link and connect communities with formal health care services...
January 11, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28077147/the-political-and-scientific-challenges-in-evaluating-compulsory-drug-treatment-centers-in-southeast-asia
#11
Thu Vuong, Nhu Nguyen, Giang Le, Marian Shanahan, Robert Ali, Alison Ritter
BACKGROUND: In Vietnam, like many countries in Southeast Asia, the commonly used approach of center-based compulsory drug treatment (CCT) has been criticized on human rights ground. Meanwhile, community-based voluntary methadone maintenance treatment (MMT) has been implemented for nearly a decade with promising results. Reform-minded leaders have been seeking empirical evidence of the costs and effectiveness associated with these two main treatment modalities. Conducting evaluations of these treatments, especially where randomization is not ethical, presents challenges...
January 11, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28076261/-how-can-we-talk-about-patient-centered-care-without-patients-at-the-table-lessons-learned-from-patient-advisory-councils
#12
Anjana E Sharma, Rachel Willard-Grace, Andrew Willis, Olivia Zieve, Kate Dubé, Charla Parker, Michael B Potter
CONTEXT AND OBJECTIVE: Patient advisory councils (PACs) are a strategy for primary care clinics to engage patients in practice improvement. However, there is scant research on how PACs function. This study aimed to understand how PACs are organized and identify common challenges and perceived benefits of high-functioning PACs. SETTING AND POPULATION: Key informants identified 8 primary care clinics in California with high-functioning PACs. Leaders from each of the 8 clinics nominated 1 clinic staff member and 1 PAC patient member to be interviewed...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28076242/bread-and-butter-of-family-medicine-guidelines-population-screening-diagnostic-evaluations-and-practice-models
#13
EDITORIAL
Dean A Seehusen, Marjorie A Bowman, Anne Victoria Neale
This issue of JABFM is full of evidence and thoughtful articles on topics central to family medicine. These articles critically examine what family physicians do on a daily basis. Reports in this issue provide new evidence regarding guidelines, screening programs, evaluation procedures, and practice models. Clinical articles report that the sensitivity of mailed Fecal Immunochemical Testing changes with the weather; a dermatoscope and a simple algorithm can help differentiate malignant from benign skin lesions; and that a few almonds can alter blood glucose levels in response to a glucose tolerance test...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28074619/too-busy-to-lead-current-challenges-for-german-nurse-leaders
#14
EDITORIAL
Renate Tewes, Thomas Fischer
No abstract text is available yet for this article.
January 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28074571/screening-brief-intervention-and-referral-to-treatment-sbirt-implementation-barriers-facilitators-and-model-migration
#15
Janice Vendetti, Amanda Gmyrek, Donna Damon, Manu Singh, Bonnie McRee, Frances Del Boca
AIMS: To identify barriers and facilitators associated with initial implementation of a US alcohol and other substance use Screening, Brief Intervention, and Referral to Treatment (SBIRT) grant program, and to identify modifications in program design that addressed implementation challenges. DESIGN: A mixed-method approach used quantitative and qualitative data, including SBIRT provider ratings of implementation barriers and facilitators, staff interview responses and program documentation...
February 2017: Addiction
https://www.readbyqxmd.com/read/28073892/socioeconomic-and-ethnic-inequities-within-organised-colorectal-cancer-screening-programmes-worldwide
#16
C M de Klerk, S Gupta, E Dekker, M L Essink-Bot
OBJECTIVE: Colorectal cancer (CRC) screening programmes can reduce CRC mortality. However, the implementation of a screening programme may create or exacerbate socioeconomic and ethnic health inequities if participation varies by subgroup. We determined which organised programmes characterise participation inequities by socioeconomic and ethnic subgroups, and assessed the variation in subgroup participation among programmes collecting group-specific data. DESIGN: Employing a literature review and survey among leaders of national or regional screening programmes, this study identified published and unpublished data on participation by socioeconomic status and ethnicity...
January 10, 2017: Gut
https://www.readbyqxmd.com/read/28071983/what-does-leaders-character-add-to-transformational-leadership
#17
Patrick Liborius
The influence of leaders' character (e.g., integrity, humility/forgiveness) has rarely been examined in leadership research. The current investigation focused on the impact of integrity and humility/forgiveness on both followers' perceptions of leaders' worthiness of being followed (WBF) and stress. Results from a scenario experiment (n = 347) and a field study (n = 110) indicated that these aspects incrementally predict WBF above and beyond the impact of transformational leadership. Similar results were found concerning followers' stress with the exception of leader integrity in the field study...
January 10, 2017: Journal of Psychology
https://www.readbyqxmd.com/read/28071861/jan-winberg-1923-2003-a-leader-in-urinary-tract-infection-research
#18
Kjell Tullus
No abstract text is available yet for this article.
February 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28071584/major-highlights-of-the-car-tcr-summit-boston-2016
#19
Vita Golubovskaya, Robert Berahovich, Shirley Xu, Hizkia Harto, Lijun Wu
Cellular immunotherapies such as CAR-T cell therapy and TCR-T cell therapy are relatively new, highly promising approaches for the treatment of cancer. In CAR-T cell therapy, a patient's T cells are engineered to express chimeric antigen receptors targeting tumor-associated cell surface antigens. In TCR-T cell therapy, the patient's T cells are engineered to express receptors targeting intracellular antigens. This report will summarize presentations from the recent CAR-TCR summit in Boston on September 13-16, 2016...
10, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28070655/synthetic-introns-help-identify-sequences-in-the-5-utr-intron-of-the-glycine-max-polyubiquitin-gmubi-promoter-that-give-increased-promoter-activity
#20
Trudi N L Grant, Carola M De La Torre, Ning Zhang, John J Finer
Specific sequences within the leader intron of a soybean polyubiquitin gene stimulated gene expression when placed either within a synthetic intron or upstream of a core promoter. The intron in the 5' untranslated region of the soybean polyubiquitin promoter, Gmubi, seems to contribute to the high activity of this promoter. To identify the stimulatory sequences within the intron, ten different sequential intronic sequences of 40 nt were isolated, cloned as tetrameric repeats and placed upstream of a minimal cauliflower mosaic virus 35S (35S) core promoter, which was used to control expression of the green fluorescent protein...
January 9, 2017: Planta
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