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https://www.readbyqxmd.com/read/29785940/metabolic-effects-safety-and-acceptability-of-very-low-calorie-ketogenic-dietetic-scheme-on-candidates-for-bariatric-surgery
#1
Vincenzo Pilone, Salvatore Tramontano, Michele Renzulli, Mafalda Romano, Luigi Cobellis, Tiziano Berselli, Luigi Schiavo
BACKGROUND: Previous studies have demonstrated significant advantages from a preoperative dietetic regimen for candidates to bariatric procedure. OBJECTIVES: Evaluation of safety, efficacy, and acceptability of a very low-calorie ketogenic diet in patients before bariatric surgery. SETTING: University Hospital. METHODS: A standardized 30-day sequential preoperative diet regimen has been analyzed, optimizing metabolic response with gradual carbohydrate reintroduction...
March 21, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29785665/why-weight-an-analytic-review-of-obesity-management-diabetes-prevention-and-cardiovascular-risk-reduction
#2
REVIEW
L I Igel, K H Saunders, J J Fins
PURPOSE OF REVIEW: In this review, we examine one of the ironies of American health care-that we pay more for disease management than disease prevention. Instead of preventing type 2 diabetes (T2DM) by treating its precursor, obesity, we fail to provide sufficient insurance coverage for weight management only to fund the more costly burden of overt T2DM. RECENT FINDINGS: There is a vital need for expanded insurance coverage to help foster a weight-centric approach to T2DM management...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29785493/mindset-and-communication-barriers-in-the-diffusion-of-bariatric-surgery
#3
REVIEW
Daniel Gero, Bors Hulesch, Marco Bueter
PURPOSE OF REVIEW: Cumulating evidence is available to demonstrate the efficacy of bariatric surgery (BS) in achieving weight loss and optimizing comorbidities. However, currently, only a minority of eligible patients approaches bariatric centers. The underuse of BS can no longer be explained by the lack of evidence supporting its beneficial outcomes along with its favorable safety-profile, rather, by the supporting infrastructure, insurance coverage, and mindset of society, including potential patients and allied healthcare professionals...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29785473/changes-in-melatonin-cortisol-and-body-temperature-and-the-relationship-between-endogenous-melatonin-levels-and-analgesia-consumption-in-patients-undergoing-bariatric-surgery
#4
Neslihan Altunkaya, Mehmet Ali Erdogan, Ulku Ozgul, Mukadder Sanli, Muharrem Ucar, Onural Ozhan, Fatih Sumer, Selim Erdogan, Cemil Colak, Mahmut Durmus
BACKGROUND: Melatonin has analgesic, anti-inflammatory, sedative, and anxiolytic properties. However, the relationship between endogenous melatonin levels and postoperative analgesic requirements has not been well elucidated in patients undergoing bariatric surgery. We studied endogenous melatonin levels, cortisol levels, body temperatures, and the relationship between the level of endogenous melatonin and postoperative morphine consumption. METHODS: The trial was conducted among 30 patients who were scheduled for laparoscopic bariatric surgery...
May 21, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29784999/publisher-correction-muscle-and-adipose-tissue-morphology-insulin-sensitivity-and-beta-cell-function-in-diabetic-and-nondiabetic-obese-patients-effects-of-bariatric-surgery
#5
Stefania Camastra, Alessandra Vitali, Marco Anselmino, Amalia Gastaldelli, Rosario Bellini, Rossana Berta, Ilenia Severi, Simona Baldi, Brenno Astiarraga, Giorgio Barbatelli, Saverio Cinti, Ele Ferrannini
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
May 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784652/mechanisms-responsible-for-metabolic-improvements-of-bariatric-surgeries
#6
John P Kirwan, Heike Münzberg, Hans-Rudolf Berthoud
No abstract text is available yet for this article.
June 2018: Diabetes
https://www.readbyqxmd.com/read/29781044/sleeve-gastrectomy-in-morbidly-obese-hiv-patients-focus-on-anti-retroviral-treatment-absorption-after-surgery
#7
Chloé Amouyal, Marion Buyse, Lea Lucas-Martini, Déborah Hirt, Laurent Genser, Adriana Torcivia, Jean-Luc Bouillot, Jean-Michel Oppert, Judith Aron-Wisnewsky
CONTEXT: Anti-retroviral therapy (ART) dramatically reduced AIDS development, thus enabling patients to live as long as the general population. New challenges have emerged particularly cardiometabolic diseases and weight gain, with some HIV patients seeking bariatric surgery (BS). However, BS outcomes during HIV remain poorly described, with scarce data on ART pharmacokinetic post-BS. OBJECTIVE: Describing sleeve gastrectomy (SG) results in HIV patients in terms of ART pharmacokinetic, HIV control, weight loss, and metabolic outcomes...
May 20, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29781038/downregulation-of-lncrna-malat1-contributes-to-renal-functional-improvement-after-duodenal-jejunal-bypass-in-a-diabetic-rat-model
#8
Dong Wu, Yu-Gang Cheng, Xin Huang, Ming-Wei Zhong, Shao-Zhuang Liu, San-Yuan Hu
Ameliorated renal function has been reported after bariatric surgery, but the mechanisms underlying this phenomenon are not well-studied. To investigate whether the long non-coding RNA (lncRNA) MALAT1 mediates the amelioration of diabetic nephropathy after duodenal-jejunal bypass (DJB) surgery, rats were assigned randomly into four groups: diabetic (DM) group, DM with DJB surgery group, DM with sham surgery group, and healthy control group. Food intake, body weight, oral glucose tolerance test (OGTT), urine albumin excretion rate (UAER), and glomerular filtration rate (GFR) were measured and histological examination of renal sections was performed...
May 21, 2018: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/29780918/bariatric-surgery-and-its-impact-on-pseudotumor-cerebri-a-case-report
#9
Norberto Mancera, Michel M Murr, Mitchell Drucker
Purpose: Pseudotumor cerebri is a debilitating condition that causes severe headaches and progressive visual field loss. In this report, we present a patient with Class III obesity, with pseudotumor cerebri who failed medical management and attempted weight loss via diet and exercise. Observations: After undergoing bariatric surgery, the patient had significant weight loss and improvement of visual field defects. Conclusion and importance: These results suggest that bariatric surgery may be an effective option for patients with rapidly progressing visual loss due to pseudotumor cerebri...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780857/multi-omic-network-based-interrogation-of-rat-liver-metabolism-following-gastric-bypass-surgery-featuring-swath-proteomics
#10
Gautham Vivek Sridharan, Matthew D'Alessandro, Shyam Sundhar Bale, Vicky Bhagat, Hugo Gagnon, John M Asara, Korkut Uygun, Martin L Yarmush, Nima Saeidi
Morbidly obese patients often elect for Roux-en-Y gastric bypass (RYGB), a form of bariatric surgery that triggers a remarkable 30% reduction in excess body weight and reversal of insulin resistance for those who are type II diabetic. A more complete understanding of the underlying molecular mechanisms that drive the complex metabolic reprogramming post-RYGB could lead to innovative non-invasive therapeutics that mimic the beneficial effects of the surgery, namely weight loss, achievement of glycemic control, or reversal of non-alcoholic steatohepatitis (NASH)...
September 2017: Technology
https://www.readbyqxmd.com/read/29780358/sex-and-gender-differences-in-prevention-of-type-2-diabetes
#11
REVIEW
Jürgen Harreiter, Alexandra Kautzky-Willer
Lifestyle intervention programs are effective in the prevention of type 2 diabetes mellitus (T2DM) in high risk populations. However, most studies only give limited information about the influence of sex and/or gender effectiveness of these interventions. So far, similar outcome was reported for diabetes progression and weight loss. Nevertheless, long-term data on cardiovascular outcome are sparse but favoring women regarding all-cause and cardiovascular mortality. In both men and women, sex hormone imbalances and reproductive disorders are associated with a higher risk of T2DM development...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29779823/the-role-of-thiamine-dependent-enzymes-in-obesity-and-obesity-related-chronic-disease-states-a-systematic-review
#12
REVIEW
Donogh Maguire, Dinesh Talwar, Paul G Shiels, Donald McMillan
The WHO 2016 report indicates that worldwide obesity is rising, with over 600 million people in the obese range (BMI>30). The recommended daily calorie intake for adults is 2000 kcal and 2500 kcal for women and men respectively. The average American consumes 3770 kcal/day and the average person in the UK consumes 3400 kcal/day. With such increased caloric intake, there is an increased load on metabolic pathways, in particular glucose metabolism. Such metabolism requires micronutrients as enzyme co-factors...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29778908/mammalian-target-of-rapamycin-complex-2-signaling-in-obese-women-changes-after-bariatric-surgery
#13
Marcela Augusta de Souza Pinhel, Carolina Ferreira Nicoletti, Natalia Yumi Noronha, Bruno Affonso Parenti de Oliveira, Cristiana Cortes-Oliveira, Wilson Salgado, Wilson Araujo da Silva, Doroteia Rossi Silva Souza, Julio Sergio Marchini, Carla Barbosa Nonino
OBJECTIVES: After bariatric surgery, modifications to signaling pathway networks including those of the metabolic regulator called mammalian or mechanistic target of rapamycin (mTOR) may lead to molecular alterations related to energy source availability, systemic nutrients, and catabolic and anabolic cellular processes. This study aimed to identify gene expression changes with regard to the mTOR complex 2 subunit signaling pathway in obese patients before and after bariatric surgery...
March 21, 2018: Nutrition
https://www.readbyqxmd.com/read/29778650/obesity-surgery-makes-patients-healthier-and-more-functional-real-world-results-from-the-united-kingdom-national-bariatric-surgery-registry
#14
Alexander Dimitri Miras, Kamocka Anna, Patel Darshan, Dexter Simon, Finlay Ian, Hopkins C James, Khan Omar, Reddy Marcus, Sedman Peter, Small Peter, Somers Shaw, Suzie Cro, Walton Peter, le Roux Carel W, Welbourn Richard
BACKGROUND: The National Bariatric Surgery Registry (NBSR) is the largest bespoke database in the field in the United Kingdom. OBJECTIVES: Our aim was to analyze the NBSR to determine whether the effects of obesity surgery on associated co-morbidities observed in small, randomized controlled clinical trials could be replicated in a "real life" setting within U.K. healthcare. SETTING: United Kingdom. METHODS: All NBSR entries for operations between 2000 and 2015 with associated demographic and co-morbidity data were analyzed retrospectively...
February 15, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29777230/serum-biomarkers-of-inflammation-and-adiposity-in-the-labs-cohort-associations-with-metabolic-disease-and-surgical-outcomes
#15
Robert W O'Rourke, Geoffrey S Johnson, Jonathan Q Purnell, Anita P Courcoulas, Gregory F Dakin, Luis Garcia, Marcelo Hinojosa, James E Mitchell, Alfons Pomp, Walter J Pories, Konstantinos Spaniolas, David R Flum, Abdus S Wahed, Bruce M Wolfe
BACKGROUND: The utility of serum biomarkers related to inflammation and adiposity as predictors of metabolic disease prevalence and outcomes after bariatric surgery are not well-defined. METHODS: Associations between pre- and post-operative serum levels of four biomarkers (C-reactive protein (CRP), cystatin C (CC), leptin, and ghrelin) with baseline measures of adiposity and metabolic disease prevalence (asthma, diabetes, sleep apnea), and weight loss and metabolic disease remission after bariatric surgery were studied in the Longitudinal Assessment of Bariatric Surgery (LABS) cohort...
May 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29776493/mechanisms-in-bariatric-surgery-gut-hormones-diabetes-resolution-and-weight-loss
#16
Jens Juul Holst, Sten Madsbad, Kirstine N Bojsen-Møller, Maria Saur Svane, Nils Bruun Jørgensen, Carsten Dirksen, Christoffer Martinussen
Gastric bypass surgery leads to profound changes in the secretion of gut hormones with effects on metabolism, appetite, and food intake. Here, we discuss their contributions to the improvement in glucose tolerance and the weight loss that results from the operations. We find that the improved glucose tolerance is due the following events: a negative energy balance and resulting weight loss, which improve first hepatic and later peripheral insulin sensitivity, in combination with increased postprandial insulin secretion elicited particularly by exaggerated glucagon-like peptide-1 responses...
May 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29776491/comment-on-insurance-mandated-preoperative-diet-and-outcomes-after-bariatric-surgery
#17
EDITORIAL
Helmuth Billy, Eric J DeMaria
No abstract text is available yet for this article.
May 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29776012/evolving-self-view-and-body-image-concerns-in-female-post-operative-bariatric-surgery-patients
#18
Tamara O Perdue, Ann Schreier, Melvin Swanson, Janice Neil, Robert Carels
AIMS AND OBJECTIVES: This research study explores the experience of post-operative bariatric surgery patients as they adjust to diminished weight and differentiates that adjustment from the more general concept of body image. BACKGROUND: Bariatric surgery is an effective way to reduce weight and co-morbidities associated with obesity. Complete success requires that patients must adjust psychologically as they lose weight. If this does not occur, bariatric patients may experience a 'mind-body lag' in which the patient's internal body image lags behind the external changes...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29774453/predictors-for-adherence-to-multidisciplinary-follow-up-care-after-sleeve-gastrectomy
#19
Ariela Goldenshluger, R Elazary, M J Cohen, M Goldenshluger, T Ben-Porat, J Nowotni, H Geraisi, M Amun, A J Pikarsky, L Keinan-Boker
INTRODUCTION: A considerable proportion of patients who undergo bariatric surgeries (BS) do not attend routine postoperative follow-up despite recommendations for such. Data are sparse regarding the various aspects of patient adherence to consultations following sleeve gastrectomy (SG). OBJECTIVES: To examine predictors of adherence to SG follow-up, reasons for attrition from follow-up, and the relationship between adherence to follow-up and weight loss results...
May 17, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29773763/initial-experience-with-endoscopic-sleeve-gastroplasty-in-poland
#20
Aleksander Sowier, Przemysław Pyda, Anna-Maria Borucka, Sebastian Sowier, Jacek Białecki, Joanna Kapturzak, Stanisław Wójtowicz
INTRODUCTION: Obesity is becoming one of the major public health problems. Bariatric procedures are considered the most effective methods of treating this condition but they are costly and entail a high risk of complications. Thus, there is a need to look for better bariatric treatment solutions. One of the newest, highly promising bariatric methods is endoscopic sleeve gastroplasty (ESG), which is comparably effective to other bariatric procedures in terms of weight loss but at the same time it is much less invasive...
April 30, 2018: Polski Przeglad Chirurgiczny
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