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contemporary reviews in cardiovascular medicine

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https://www.readbyqxmd.com/read/27765361/aralia-elata-var-mandshurica-rupr-maxim-j-wen-an-overview-of-pharmacological-studies
#1
Alexander N Shikov, Olga N Pozharitskaya, Valery G Makarov
PURPOSE: Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen syn. A. mandshurica Rupr. & Maxim is evaluated for its medicinal application. The aim of this study is to analyze pharmacological studies on A. elata var. mandshurica published until December 2015. METHODS: The information regarding the chemistry, safety, effectiveness, and pharmacological and clinical effects of A. elata was systematically collected from the scientific literature through library catalogs; online services such as E-library...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27598000/how-valuable-is-physical-examination-of-the-cardiovascular-system
#2
REVIEW
Andrew Elder, Alan Japp, Abraham Verghese
Physical examination of the cardiovascular system is central to contemporary teaching and practice in clinical medicine. Evidence about its value focuses on its diagnostic accuracy and varies widely in methodological quality and statistical power. This makes collation, analysis, and understanding of results difficult and limits their application to daily clinical practice. Specific factors affecting interpretation and clinical application include poor standardisation of observers' technique and training, the study of single signs rather than multiple signs or signs in combination with symptoms, and the tendency to compare physical examination directly with technological aids to diagnosis rather than explore diagnostic strategies that combine both...
July 27, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27553599/glycemic-control-for-patients-with-type-2-diabetes-mellitus-our-evolving-faith-in-the-face-of-evidence
#3
René Rodríguez-Gutiérrez, Victor M Montori
BACKGROUND: We sought to determine the concordance between the accumulating evidence about the impact of tight versus less tight glycemic control in patients with type 2 diabetes mellitus since the publication of UKPDS (UK Prospective Diabetes Study) in 1998 until 2015 with the views about that evidence published in journal articles and practice guidelines. METHODS AND RESULTS: We searched in top general medicine and specialty journals for articles referring to glycemic control appearing between 2006 and 2015 and identified the latest practice guidelines...
September 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27322757/contemporary-developments-in-the-discovery-of-selective-factor-xa-inhibitors-a-review
#4
REVIEW
Nirav R Patel, Dushyant V Patel, Prashant R Murumkar, Mange Ram Yadav
Thrombosis is a leading cause of death in cardiovascular diseases such as myocardial infarction (MI), unstable angina and acute coronary syndrome (ACS) in the industrialized world. Venous thromboembolism is observed in about 1 million people every year in United States causing significant morbidity and mortality. Conventional antithrombotic therapy has been reported to have several disadvantages and limitations like inconvenience in oral administration, bleeding risks (heparin analogs), narrow therapeutic window and undesirable interactions with food and drugs (vitamin K antagonist-warfarin)...
October 4, 2016: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/26081680/the-international-society-for-sexual-medicine-s-process-of-care-for-the-assessment-and-management-of-testosterone-deficiency-in-adult-men
#5
REVIEW
John D Dean, Chris G McMahon, Andre T Guay, Abraham Morgentaler, Stanley E Althof, Edgardo F Becher, Trinity J Bivalacqua, Arthur L Burnett, Jacques Buvat, Amr El Meliegy, Wayne J G Hellstrom, Emmanuele A Jannini, Mario Maggi, Andrew McCullough, Luiz Otavio Torres, Michael Zitzmann
INTRODUCTION: In 2014, the International Society for Sexual Medicine (ISSM) convened a panel of experts to develop an evidence-based process of care for the diagnosis and management of testosterone deficiency (TD) in adult men. The panel considered the definition, epidemiology, etiology, physiologic effects, diagnosis, assessment and treatment of TD. It also considered the treatment of TD in special populations and commented on contemporary controversies about testosterone replacement therapy, cardiovascular risk and prostate cancer...
August 2015: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/25356301/an-evidence-based-unified-definition-of-lifelong-and-acquired-premature-ejaculation-report-of-the-second-international-society-for-sexual-medicine-ad-hoc-committee-for-the-definition-of-premature-ejaculation
#6
REVIEW
Ege Can Serefoglu, Chris G McMahon, Marcel D Waldinger, Stanley E Althof, Alan Shindel, Ganesh Adaikan, Edgardo F Becher, John Dean, Francois Giuliano, Wayne Jg Hellstrom, Annamaria Giraldi, Sidney Glina, Luca Incrocci, Emmanuele Jannini, Marita McCabe, Sharon Parish, David Rowland, R Taylor Segraves, Ira Sharlip, Luiz Otavio Torres
INTRODUCTION: The International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature Ejaculation developed the first evidence-based definition for lifelong premature ejaculation (PE) in 2007 and concluded that there were insufficient published objective data at that time to develop a definition for acquired PE. AIM: The aim of this article is to review and critique the current literature and develop a contemporary, evidence-based definition for acquired PE and/or a unified definition for both lifelong and acquired PE...
June 2014: Sexual Medicine
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