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https://www.readbyqxmd.com/read/28802464/mirage-events-driver-haptic-steering-alerts-in-a-motion-base-driving-simulator-a-method-for-selecting-an-optimal-hmi
#1
Walter Talamonti, Louis Tijerina, Mike Blommer, Radhakrishnan Swaminathan, Reates Curry, R Darin Ellis
This paper describes a new method, a 'mirage scenario,' to support formative evaluation of driver alerting or warning displays for manual and automated driving. This method provides driving contexts (e.g., various Times-To-Collision (TTCs) to a lead vehicle) briefly presented and then removed. In the present study, during each mirage event, a haptic steering display was evaluated. This haptic display indicated a steering response may be initiated to drive around an obstacle ahead. A motion-base simulator was used in a 32-participant study to present vehicle motion cues similar to the actual application...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28790934/skin-lesions-in-swine-with-decompression-sickness-clinical-appearance-and-pathogenesis
#2
Long Qing, Dinesh K Ariyadewa, Hongjie Yi, Yewei Wang, Quan Zhou, Weigang Xu
Skin lesions are visual clinical manifestations of decompression sickness (DCS). Comprehensive knowledge of skin lesions would give simple but strong clinical evidence to help diagnose DCS. The aim of this study was to systematically depict skin lesions and explore their pathophysiological basis in a swine DCS model. Thirteen Bama swine underwent simulated diving in a hyperbaric animal chamber with the profile of 40 msw-35 min exposure, followed by decompression in 11 min. After decompression, chronological changes in the appearance of skin lesions, skin ultrasound, temperature, tissue nitric oxide (NO) levels, and histopathology were studied...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28777901/metabonomic-potential-plasma-biomarkers-in-abnormal-fast-buoyancy-ascent-escape-induced-decompression-sickness-model-and-the-protective-effects-of-pyrrolidine-dithiocarbamic-acid
#3
Fan Yiqun, You Pu, Wang Haitao, Bao Xiaochen, Ma Jun, Zhang Shi, Fan Yinghui
BACKGROUND: Decompression sickness (DCS) induced by fast buoyancy ascent escape (FBAE) is a special DCS, characterized with cardiopulmonary injuries. Serum metabonomics of this type of DCS has not yet been studied. We proposed a metabonomics approach for assessing serum metabonomics changes and evaluating the preventive effect of pyrrolidine dithiocarbamic acid (PDTC) in FBAE-induced DCS rats. METHODS: Sixty-five (65) rats were divided into three groups, including the Control, DCS and PDTC groups...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28731987/evidence-of-heritable-determinants-of-decompression-sickness-in-rats
#4
Jacky Lautridou, Peter Buzzacott, Marc Belhomme, Emmanuel Dugrenot, Pierre Lafère, Costantino Balestra, François Guerrero
INTRODUCTION: Decompression sickness (DCS) is a complex and poorly understood systemic disease caused by inadequate desaturation following a decrease of ambient pressure. Strong variability between individuals is observed for DCS occurrence. This raises questions concerning factors that may be involved in the inter-individual variability of DCS occurrence. This study aimed to experimentally assess the existence of heritable factors involved in DCS occurrence by selectively breeding individuals resistant to DCS from a population stock of wistar rats...
July 20, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28723718/three-dimensional-head-mounted-gaming-task-procedure-maximizes-effects-of-vestibular-rehabilitation-in-unilateral-vestibular-hypofunction-a-randomized-controlled-pilot-trial
#5
Alessandro Micarelli, Andrea Viziano, Ivan Augimeri, Domenico Micarelli, Marco Alessandrini
Considering the emerging advantages related to virtual reality implementation in clinical rehabilitation, the aim of the present study was to discover possible (i) improvements achievable in unilateral vestibular hypofunction patients using a self-assessed head-mounted device (HMD)-based gaming procedure when combined with a classical vestibular rehabilitation protocol (HMD group) as compared with a group undergoing only vestibular rehabilitation and (ii) HMD procedure-related side effects. Therefore, 24 vestibular rehabilitation and 23-matched HMD unilateral vestibular hypofunction individuals simultaneously underwent a 4-week rehabilitation protocol...
July 18, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28660325/-i-will-do-laparoscopy-somewhere-else-total-highly-immersive-virtual-reality-without-side-effects
#6
T Huber, M Paschold, C Hansen, H Lang, W Kneist
BACKGROUND: For virtual reality laparosopic simulation we developed a new, highly immersive simulation mode. The goal of the current pilot study was to investigate if kinetosis or other negative vegetative side effects can be caused by a total virtual training set-up (TVRL). METHODS: In this study 20 participants with varying degrees of expertise in laparoscopy performed 3 tasks (i.e. ring exchange, fine dissection and cholecystectomy) in regular (VRL) and immersive mode (TVRL) with a head-mounted display (HMD) on a laparoscopic simulator...
June 28, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28653390/interventions-for-preventing-high-altitude-illness-part-1-commonly-used-classes-of-drugs
#7
REVIEW
Víctor H Nieto Estrada, Daniel Molano Franco, Roger David Medina, Alejandro G Gonzalez Garay, Arturo J Martí-Carvajal, Ingrid Arevalo-Rodriguez
BACKGROUND: High altitude illness (HAI) is a term used to describe a group of cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres (8202 feet). Acute hypoxia, acute mountain sickness (AMS), high altitude cerebral oedema (HACE) and high altitude pulmonary oedema (HAPE) are reported as potential medical problems associated with high altitude. In this review, the first in a series of three about preventive strategies for HAI, we assess the effectiveness of six of the most recommended classes of pharmacological interventions...
June 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28649590/enhancing-data-visualisation-to-capture-the-simulator-sickness-phenomenon-on-the-usefulness-of-radar-charts
#8
Romain Chaumillon, Thomas Romeas, Charles Paillard, Delphine Bernardin, Guillaume Giraudet, Jean-François Bouchard, Jocelyn Faubert
The data presented in this article are related to the research article entitled "The use of transdermal scopolamine to solve methodological issues raised by gender differences in susceptibility to simulator sickness" (Chaumillon et al., 2017) [1]. In an outstanding first demonstration, Kennedy et al. [2] showed that the Simulator Sickness Questionnaire (SSQ) is an appropriate tool to suit the purposes of characterizing motion sickness experienced in virtual environments. This questionnaire has since been used in many scientific studies...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28641682/health-effects-of-airline-cabin-environments-in-simulated-8-hour-flights
#9
(no author information available yet)
INTRODUCTION: Commercial air travel is usually without health incidents. However, there is a view that cabin environments may be detrimental to health, especially flights of 8 h or more. Concerns have been raised about deep vein thrombosis, upper respiratory tract infections, altitude sickness, and toxins from the engines. METHODS: Passenger cabin simulators were used to achieve a comparative observational study with 8-h flights at pressures equivalent to terrestrial altitudes of ground, 4000, 6000, and 8000 ft...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28641681/the-effects-of-training-on-anxiety-and-task-performance-in-simulated-suborbital-spaceflight
#10
Rebecca S Blue, Frederick Bonato, Kimberly Seaton, Andrea Bubka, Johnené L Vardiman, Charles Mathers, Tarah L Castleberry, James M Vanderploeg
INTRODUCTION: In commercial spaceflight, anxiety could become mission-impacting, causing negative experiences or endangering the flight itself. We studied layperson response to four varied-length training programs (ranging from 1 h-2 d of preparation) prior to centrifuge simulation of launch and re-entry acceleration profiles expected during suborbital spaceflight. We examined subject task execution, evaluating performance in high-stress conditions. We sought to identify any trends in demographics, hemodynamics, or similar factors in subjects with the highest anxiety or poorest tolerance of the experience...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28634889/the-efficacy-of-airflow-and-seat-vibration-on-reducing-visually-induced-motion-sickness
#11
Sarah D'Amour, Jelte E Bos, Behrang Keshavarz
Visually induced motion sickness (VIMS) is a well-known sensation in virtual environments and simulators, typically characterized by a variety of symptoms such as pallor, sweating, dizziness, fatigue, and/or nausea. Numerous methods to reduce VIMS have been previously introduced; however, a reliable countermeasure is still missing. In the present study, the effect of airflow and seat vibration to alleviate VIMS was investigated. Eighty-two participants were randomly assigned to one of four groups (airflow, vibration, combined airflow and vibration, and control) and then exposed to a 15 min long video of a bicycle ride shot from first-person view...
June 20, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28623924/in-vitro-physiological-and-antibacterial-characterization-of-zno-nanoparticle-composites-in-simulated-porcine-gastric-and-enteric-fluids
#12
Marina S R Barreto, Cristina T Andrade, Luiz Cláudio R P da Silva, Lúcio M Cabral, Vânia M Flosi Paschoalin, Eduardo M Del Aguila
BACKGROUND: Diarrhea in piglets is one of the main causes of animal death after weaning; zinc oxide (ZnO) has been used in high doses for the control of this sickness. The aim of this study was to determine the physicochemical properties of ZnO nanoparticles synthesized and immobilized on a chitosan/alginate (CH/SA) complex and investigate the antimicrobial activity and in vitro release profile of zinc (Zn(2+)) from these new compounds. The ZnO nanoparticles composites were prepared and combined with CH/SA or CH/SA and sodium tripolyphosphate (TPP)...
June 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28555125/determinants-of-motion-sickness-in-tilting-trains-coriolis-cross-coupling-stimuli-and-tilt-delay
#13
Giovanni Bertolini, Meek Angela Durmaz, Kim Ferrari, Alexander Küffer, Charlotte Lambert, Dominik Straumann
Faster trains require tilting of the cars to counterbalance the centrifugal forces during curves. Motion sensitive passengers, however, complain of discomfort and overt motion sickness. A recent study comparing different control systems in a tilting train, suggested that the delay of car tilts relative to the curve of the track contributes to motion sickness. Other aspects of the motion stimuli, like the lateral accelerations and the car jitters, differed between the tested conditions and prevented a final conclusion on the role of tilt delay...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28538515/effect-of-exposure-to-short-wavelength-light-on-susceptibility-to-motion-sickness
#14
Kyungshil Kim, Kazumi Hirayama, Kazuki Yoshida, Rika Yano, Masayuki Abe, Mika Otsuki, Satoshi Sakuraba, Shinya Sakai
This randomized cross-over study tested the hypothesis that exposure to short-wavelength light induces symptoms of motion sickness (MS). The study participants were 28 healthy adults (14 women; mean age±SD, 25.96±3.11 years). Two stimuli oscillating within a range of 0.4-0.6 Hz were used to induce MS: a blue wave stimulus with short-wavelength light (460 nm) and a green wave stimulus with middle-wavelength light (555 nm). All participants were exposed to both stimuli throughout two separate periods...
July 5, 2017: Neuroreport
https://www.readbyqxmd.com/read/28533889/effects-of-low-dose-acetazolamide-on-exercise-performance-in-simulated-altitude
#15
Ernst Elisabeth, Gatterer Hannes, Burtscher Johannes, Faulhaber Martin, Pocecco Elena, Burtscher Martin
Preventive effects of acetazolamide (ACZ) on acute mountain sickness (AMS) are well established but effects on exercise performance at high altitude or in hypoxia have been less considered and are still inconsistent. We hypothesized that low-dose ACZ would not impair exercise performance at simulated high altitude. Thus, the aim of this study was to evaluate the interaction between low-dose ACZ and exercise performance in normobaric hypoxia. Sixteen subjects (8 males and 8 females) were randomly assigned either to receive low-dose ACZ (3×125 mg in 36 hours) or placebo...
2017: International Journal of Physiology, Pathophysiology and Pharmacology
https://www.readbyqxmd.com/read/28533143/drugs-in-space-pharmacokinetics-and-pharmacodynamics-in-astronauts
#16
REVIEW
Johannes Kast, Yichao Yu, Christoph N Seubert, Virginia E Wotring, Hartmut Derendorf
Space agencies are working intensely to push the current boundaries of human spaceflight by sending astronauts deeper into space than ever before, including missions to Mars and asteroids. Spaceflight alters human physiology due to fluid shifts, muscle and bone loss, immune system dysregulation, and changes in the gastrointestinal tract and metabolic enzymes. These alterations may change the pharmacokinetics and/or pharmacodynamics of medications used by astronauts and subsequently might impact drug efficacy and safety...
May 19, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28518001/propranolol-effects-on-decompression-sickness-in-a-simulated-dissub-rescue-in-swine
#17
Angela S Forbes, David P Regis, Aaron A Hall, Richard T Mahon, William A Cronin
INTRODUCTION: Disabled submarine (DISSUB) survivors may face elevated CO2 levels and inert gas saturation, putting them at risk for CO2 toxicity and decompression sickness (DCS). Propranolol was shown to reduce CO2 production in an experimental DISSUB model in humans but its effects on DCS in a DISSUB rescue scenario are unknown. A 100% oxygen prebreathe (OPB) reduces DCS incidence and severity and is incorporated into some DISSUB rescue protocols. We used a swine model of DISSUB rescue to study the effect of propranolol on DCS incidence and mortality with and without an OPB...
April 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28513545/a-study-on-immersion-and-presence-of-a-portable-hand-haptic-system-for-immersive-virtual-reality
#18
Mingyu Kim, Changyu Jeon, Jinmo Kim
This paper proposes a portable hand haptic system using Leap Motion as a haptic interface that can be used in various virtual reality (VR) applications. The proposed hand haptic system was designed as an Arduino-based sensor architecture to enable a variety of tactile senses at low cost, and is also equipped with a portable wristband. As a haptic system designed for tactile feedback, the proposed system first identifies the left and right hands and then sends tactile senses (vibration and heat) to each fingertip (thumb and index finger)...
May 17, 2017: Sensors
https://www.readbyqxmd.com/read/28400370/the-role-of-specific-visual-subfields-in-collisions-with-oncoming-cars-during-simulated-driving-in-patients-with-advanced-glaucoma
#19
Shiho Kunimatsu-Sanuki, Aiko Iwase, Makoto Araie, Yuki Aoki, Takeshi Hara, Takeo Fukuchi, Sachiko Udagawa, Shinji Ohkubo, Kazuhisa Sugiyama, Chota Matsumoto, Toru Nakazawa, Takuhiro Yamaguchi, Hiroshi Ono
BACKGROUND/AIMS: To assess the role of specific visual subfields in collisions with oncoming cars during simulated driving in patients with advanced glaucoma. METHODS: Normal subjects and patients with glaucoma with mean deviation <-12 dB in both eyes (Humphrey Field Analyzer 24-2 SITA-S program) used a driving simulator (DS; Honda Motor, Tokyo). Two scenarios in which oncoming cars turned right crossing the driver's path were chosen. We compared the binocular integrated visual field (IVF) in the patients who were involved in collisions and those who were not...
July 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28396299/plasma-cytokine-profiling-to-predict-susceptibility-to-acute-mountain-sickness
#20
Hui Lu, Rong Wang, Wenbin Li, Hua Xie, Chang Wang, Ying Hao, Yuhuan Sun, Zhengping Jia
Extensive studies have been performed on acute mountain sickness (AMS), but biomarkers predicting AMS are lacking. Presently, the mainstay methods to identify AMS biomarkers include proteomic and genetic methods at high altitudes or in hypoxic simulated chambers. In the present study, we compared plasma cytokine profiles between AMS-susceptible individuals and AMS-resistant individuals at low altitude by cytokine array analysis. In total, 75 differentially expressed cytokines were identified between AMS-susceptible individuals and AMS-resistant individuals, most involved in inflammation...
November 1, 2016: European Cytokine Network
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