Read by QxMD icon Read

Polyacrylic acid

G S Offeddu, I Mela, P Jeggle, R M Henderson, S K Smoukov, M L Oyen
Cartilage is a structural tissue with unique mechanical properties deriving from its electrically-charged porous structure. Traditional three-dimensional environments for the culture of cells fail to display the complex physical response displayed by the natural tissue. In this work, the reproduction of the charged environment found in cartilage is achieved using polyelectrolyte hydrogels based on polyvinyl alcohol and polyacrylic acid. The mechanical response and morphology of microporous physically-crosslinked cryogels are compared to those of heat-treated chemical gels made from the same polymers, as a result of pH-dependent swelling...
February 23, 2017: Scientific Reports
Jasna Lojk, Klemen Strojan, Katarina Miš, Boštjan Vladimir Bregar, Iva Hafner Bratkovič, Maruša Bizjak, Sergej Pirkmajer
Potential nanoparticle (NP) toxicity is one of crucial problems that limit the applicability of NPs. When designing NPs for biomedical and biotechnological applications it is thus important to understand the mechanisms of their toxicity. In this study, we analysed the stress responses of previously designed polyacrylic acid (PAA) and polyethylenimine (PEI) coated NPs on primary human myoblasts (MYO) and B16 mouse melanoma cell line. Negatively charged PAA did not induce cell toxicity, reactive oxygen species (ROS) or activate the transcription factor NF-κB in either cell line even at high concentrations (100μg/ml)...
February 18, 2017: Toxicology Letters
Abdol-Mohammad Kajbafzadeh, Shabnam Sabetkish, Reza Khorramirouz, Nastaran Sabetkish
OBJECTIVES: To compare short- and long-term local tissue reaction of polyacrylate polyalcohol copolymer (PPC) with dextranomer/hyaluronic acid (DHA) in rabbits. METHODS: Eight healthy New Zealand rabbits were randomly divided into two groups. In group I (control group), DHA was injected just beneath the mucosal layer of the bladder wall, while PPC was injected in group II. Subcutaneous injection of both bulking agents was also performed in nude mice. Histological evaluations with leukocyte common antibody (LCA), CD68, CD31, and CD34 were conducted on biopsies 1 and 6 months postoperatively...
February 16, 2017: International Urology and Nephrology
Huiru Ma, Kai Tang, Wei Luo, Lin Ma, Qian Cui, Wei Li, Jianguo Guan
Herein, we use experiments and numerical simulations to demonstrate a novel class of magnetically responsive photonic crystals (MRPCs) based on photonic nanorods which exhibit multiple optical properties in a magnetic field (H) due to their fixed photonic nanorods and H-tunable lattice defects. As an example, superparamagnetic Fe3O4@polyvinyl pyrrolidone (PVP)@SiO2 photonic nanorods were fabricated through a polyacrylic acid-catalysed hydrolysis-condensation reaction of γ-mercaptopropyltrimethoxysilane around chain-like PC templates formed by monodispersed Fe3O4@PVP particles under H...
February 15, 2017: Nanoscale
Lida Ahmadkhani, Ali Baghban, Shahram Mohammadpoor, Rovshan Khalilov, Abolfazl Akbarzadeh, Taras Kavetskyy, Siamak Saghfi, Aygun N Nasibova
Through the present paper, a triblock copolymer containing pH-responsive (polyacrylic acid-b-polycaprolactone -b-polyacrylic acid) (PAA-b-PCL-b-PAA) was synthesized by using the ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) and the reversible addition fragmentation chain transfer (RAFT) polymerization of the acrylic acid methods, as the drug carrier. Blends of the nanocrystalline zinc oxide nanoparticles (n-ZnO) and triblock copolymer treated from the solution have been used to make the hybrid polymer-metal oxide for the preparation of the drug loaded nanocomposite...
February 14, 2017: Drug Research
S K Tripathi, Z Ahmadi, K C Gupta, P Kumar
No abstract text is available yet for this article.
February 8, 2017: Colloids and Surfaces. B, Biointerfaces
Daniela Rodrigues, Marisa Freitas, Vera Marisa Costa, M Arturo Lopez-Quintela, José Rivas, Paulo Freitas, Félix Carvalho, Eduarda Fernandes, Paula Silva
Understanding in vivo biodistribution of iron oxide nanoparticles (IONs), and the involvement of the phagocyte system in this process, is crucial for the assessment of their potential health risk. In the present study, the histochemical expression of iron in spleen and liver sections of CD-1 mice (aged 8 weeks) was quantified, 24 hours after intravenous administration of polyacrylic acid-coated IONs (PAA-coated IONs) (8, 20, 50 mg/kg). Organ sections were stained with Perls' Prussian blue for iron detection, followed by the quantification of iron deposition with ImageJ software...
February 6, 2017: Nanotoxicology
Y Tian, N Grishkewich, L Bromberg, T Alan Hatton, Kam C Tam
The binding of doxorubicin (DOX) to cross-linked Pluronic F127-g-PAA-EGDMA and L92-g-PAA-EGDMA microgels at different alpha (α) and salt concentrations was investigated using isothermal titration calorimetric (ITC), optical and scanning electron microscopic techniques (SEM). We seek to elucidate the mechanisms of interaction and the release of DOX from cross-linked microgels composed of Pluronic and poly(acrylic acid). The ITC results indicated a high binding affinity of DOX to the microgel, which is a function of salt concentrations due to the impact of electrostatic shielding on the DOX-binding process...
January 23, 2017: European Journal of Pharmaceutics and Biopharmaceutics
Zhanhui Shen, Jialu Shi, Shuzhan Zhang, Jing Fan, JianSheng Li
The mixture of 1-hydroxyethane-1,1-diphosphonic acid (HEDP), and polyacrylic acid (PAA) and synthesized hydrolyzed polymaleic anhydride (HPMA) was optimized by using simplex lattice of Design-Expert software through calcium carbonate precipitation method. The optimum mass ratio of HEDP, PAA and synthesized HPMA was obtained at 10/10/80, which showed excellent performance on controlling calcium carbonate deposition. The antiscale efficiency of the optimum mixture was 84% and 95%, respectively, in the calcium carbonate precipitation test and the calcium carbonate scale deposit test...
January 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
Yazhen Shen, Changwen Du, Jianmin Zhou, Fei Ma
Acrylic latexes are valuable waterborne materials used in controlled-release fertilizers. Controlled-release urea coated with these latexes releases a large amount of nutrients, making it difficult to meet the requirement of plants. Herein, Fe(III)-tannic acid (TA) complexes were blended with acrylic latex and subsequently reassembled on a surface of polyacrylate particles. These complexes remarkably retarded the release of urea (the preliminary solubility was decreased from 22.3 to 0.8%) via decreasing the coating tackiness (Tg was increased from 4...
January 30, 2017: Journal of Agricultural and Food Chemistry
Arindam Saha, Subas Chandra Mohanta, Kashmiri Deka, Pritam Deb, Parukuttyamma Sujatha Devi
In this paper, we report the synthesis of surface-engineered multifunctional Eu:Gd2O3 triangular nanoplates with small size and uniform shape via a high-temperature solvothermal technique. Surface engineering has been performed by a one-step polyacrylate coating, followed by controlled conjugation chemistry. This creates the desired number of surface functional groups that can be used to attach folic acid as a targeting ligand on the nanoparticle surface. To specifically deliver the drug molecules in the nucleus, the folate density on the nanoparticle surface has been kept low...
February 1, 2017: ACS Applied Materials & Interfaces
Jean-François Cotte, Afifa Bouadam, Agathe Sordoillet, Isabelle Jaudinaud, Véronique Chambon, Philippe Talaga
Synthetic polyelectrolytes are a broad class of vaccine adjuvants. Among them, polyacrylic acid (PAA), a polyanionic polymer, is currently evaluated by Sanofi Pasteur. As chain length is considered to be a critical quality attribute for adjuvant properties of PAA, measurement of precise and accurate molecular size parameters is important for these polymers. In the field of synthetic polymer chemistry, methods for determination of molecular size parameters are well defined. Specifically, high performance size-exclusion chromatography (HPSEC) with multi-detection system is a method of choice...
January 11, 2017: Analytical and Bioanalytical Chemistry
Hao Wang, Tingting Dai, Shuyan Zhou, Xiaoxiao Huang, Songying Li, Kang Sun, Guangdong Zhou, Hongjing Dou
In order to overcome the key challenge in improving both fabrication efficiency and their drug delivery capability of anti-cancer drug delivery systems (ACDDS), here polyacrylic acid (PAA) grafted dextran (Dex) nanohydrogels (NGs) with covalent crosslinked structure bearing redox sensitive disulfide crosslinking junctions (Dex-SS-PAA) were synthesized efficiently through a one-step self-assembly assisted methodology (SAA). The Dex-SS-PAA were subsequently conjugated with doxorubicin through an acid-labile hydrazone bond (Dex-SS-PAA-DOX)...
January 10, 2017: Scientific Reports
Klemen Strojan, Adrijana Leonardi, Vladimir B Bregar, Igor Križaj, Jurij Svete, Mojca Pavlin
Protein corona of nanoparticles (NPs), which forms when these particles come in to contact with protein-containing fluids, is considered as an overlooked factor in nanomedicine. Through numerous studies it has been becoming increasingly evident that it importantly dictates the interaction of NPs with their surroundings. Several factors that determine the compositions of NPs protein corona have been identified in recent years, but one has remained largely ignored-the composition of media used for dispersion of NPs...
2017: PloS One
Bruna Borelli, Fernando Zarone, Virginia Rivieccio, Francesco Riccitiello, Michele Simeone, Roberto Sorrentino, Sandro Rengo, Gianrico Spagnuolo, Alfredo Procino
Studies have failed to identify the molecular mechanisms that regulate the genotoxic and cytotoxic effects of methacrylate resins, which are important in the biocompatibility of dental materials. Interleukin (IL)-6 has a crucial role in the control of acute-phase protein response during inflammation. In humans, the synthesis and release of two major acute-phase proteins, C-reactive protein and serum amyloid A, are regulated by IL-6. This study focused on IL-6 and activation of its receptors gp80 and gp130 in human gingival fibroblasts in order to assess the effects of the commercial acid resins Jet Kit, Unifast, and Duralay on control of inflammation...
December 28, 2016: Journal of Oral Science
Nitin Kore, Pavel Pazdera
A method for preparation of a new stable Cu(I) catalyst supported on weakly acidic polyacrylate resin without additional stabilizing ligands is described. A simple and efficient methodology for Ullmann Cu(I) catalyzed C-N cross coupling reactions using this original catalyst is reported. Coupling reactions of 4-chloropyridinium chloride with anilines containing electron donating (EDG) or electron withdrawing (EWG) groups, naphthalen-2-amine and piperazine, respectively, are successfully demonstrated.
December 22, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Jonatan Henschen, Per A Larsson, Josefin Illergård, Monica Ek, Lars Wågberg
Cellulose nanofibril (CNF) materials have been widely studied in recent years and are suggested for a wide range of applications, e.g., medical and hygiene products. One property not very well studied is the interaction between bacteria and these materials and how this can be controlled. The current work studies how bacteria adhere to different CNF materials modified with polyelectrolyte multilayers. The tested materials were TEMPO-oxidized to have different surface charges, periodate-oxidized to vary the water interaction and hot-pressed to alter the surface structure...
December 15, 2016: Colloids and Surfaces. B, Biointerfaces
Shiyu Wu, Lisha Gu, Zihua Huang, Qiurong Sun, Huimin Chen, Junqi Ling, Sui Mai
The biomimetic remineralization of apatite-depleted dentin is a potential method for enhancing the durability of resin-dentin bonding. To advance this strategy from its initial proof-of-concept design, we sought to investigate the characteristics of polyacrylic acid (PAA) adsorption to desorption from type I collagen and to test the mineralization ability of PAA-bound collagen. Portland cement and β-tricalcium phosphate (β-TCP) were homogenized with a hydrophilic resin blend to produce experimental resins...
December 20, 2016: European Journal of Oral Sciences
Suk-Yong Jang, Sien-Ho Han
Currently, Si as an active material for LIBs has been attracting much attention due to its high theoretical specific capacity (3572 mAh g(-1)). However, a disadvantage when using a Si negative electrode for LIBs is the abrupt drop of its capabilities during the cycling process. Therefore, there have been a few studies of polymers such as poly(vinylidene fluoride) (PVdF), carboxymethyl cellulose (CMC), styrene butadiene rubber (SBR) and polyacrylic acid (PAA) given that the robust structure of a polymeric binder to LIBs anodes is a promising means by which to enhance the performance of high-capacity anodes...
December 19, 2016: Scientific Reports
Olga I Bogdanova, Dmitry K Polyakov, Dmitry R Streltsov, Alevtina I Kulebyakina, Anton S Orekhov, Alexander L Vasiliev, John Blackwell, Sergey N Chvalun
Squid β-chitin has been exfoliated in aqueous acrylic acid (AA), after which a composite film of chitin microfibrils in polyacrylic acid (PAA) has been prepared by in situ polymerization of the AA. The segregated chitin fibrils in the composite are 4-6nm in diameter, with an aspect ratio >250. After drying cast films of the composites containing 1, 2 and 3% (w/w) chitin at 140°C for four hours, there was a dramatic resistance to swelling in water, in that the dried films showed only small changes in shape and properties after four hours immersed in water...
February 10, 2017: Carbohydrate Polymers
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"