keyword
https://read.qxmd.com/read/38533624/a-review-on-topical-ophthalmic-drug-delivery-system-reference-to-viscosity-enhancer
#1
REVIEW
Pravin Kondiba Pawar, Raju Dubaji Rathod, Satyajeet Ramesh Jagadale
The eye is the most accessible site for topical drug delivery. Drug's ocular bioavailability is quite low when administered topically as eye drops. Viscosity enhancers are used to increase ocular bioavailability by extending the precorneal residence time of the drug at the ocular site. Cellulose, polyalcohol and polyacrylic acid are examples of hydrophilic viscosity enhancers. The addition of viscosity modifiers increases the amount of time the drug is in contact with the ocular surface. Several polysaccharides have been studied as excipients and viscosity boosters for ocular formulations, including cellulose derivatives such as chitosan (CS), xyloglucan and arabinogalactan (methylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose (HPMC), and sodium carboxymethylcellulose)...
March 27, 2024: Polimery W Medycynie
https://read.qxmd.com/read/38497336/adsorption-isotherm-and-mechanism-of-ca-2-binding-to-polyelectrolyte
#2
JOURNAL ARTICLE
Sriteja Mantha, Alec Glisman, Decai Yu, Eric P Wasserman, Scott Backer, Zhen-Gang Wang
Polyelectrolytes, such as poly(acrylic acid) (PAA), can effectively mitigate CaCO3 scale formation. Despite their success as antiscalants, the underlying mechanism of binding of Ca2+ to polyelectrolyte chains remains unresolved. Through all-atom molecular dynamics simulations, we constructed an adsorption isotherm of Ca2+ binding to sodium polyacrylate (NaPAA) and investigated the associated binding mechanism. We find that the number of calcium ions adsorbed [Ca2+ ]ads to the polymer saturates at moderately high concentrations of free calcium ions [Ca2+ ]aq in the solution...
March 18, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38247778/nfes-embedded-into-cryogels-for-high-efficiency-removal-of-cr-vi-from-mechanism-to-for-treatment-of-industrial-wastewater
#3
JOURNAL ARTICLE
Peng Xu, Shaojun Jiang
Most studies have focused on complex strategies for materials preparation instead of industrial wastewater treatment due to emergency treatment requirements for metal pollution. This study evaluated sodium polyacrylate (PSA) as a carbon skeleton and FeS as a functional material to synthesize PSA-nFeS material. The characteristics and interactions of PSA-nFeS composites treated with hexavalent chromium were analyzed by means of various techniques, such as scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDS), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectrometry (FTIR), and atomic absorption spectroscopy (AAS)...
January 11, 2024: Gels
https://read.qxmd.com/read/38211686/effect-of-calcium-coacervate-infiltration-of-artificial-enamel-caries-lesions-in-de-and-remineralizing-conditions
#4
JOURNAL ARTICLE
Basel Kharbot, Neziha Bulgun, Helmut Cölfen, Sebastian Paris
OBJECTIVES: Calcium-coacervate emulsions (CC) might be considered as mineral precursors to foster remineralization of carious dental hard tissues. This study analyzed the instant effect of repeated infiltration of artificial caries lesions with a CC emulsion as well as the effects of subsequent exposure of CC-infiltrated lesions to demineralizing and remineralizing environments. METHODS: Bovine enamel specimens were partly covered with varnish to leave three exposed windows...
January 9, 2024: Journal of Dentistry
https://read.qxmd.com/read/38201767/enhancing-the-toughness-of-paa-lcnf-sa-hydrogel-through-double-network-crosslinking-for-strain-sensor-application
#5
JOURNAL ARTICLE
Xin Li, Hui Gao, Qiang Wang, Shanshan Liu
Lignin-containing nanocellulose fibers (LCNF) have been considered as a valuable enhancer for polyacrylic acid (PAA)-based hydrogels that can form rigid porous network structures and provide abundant polar groups. However, the PAA-LCNF hydrogel is dominated by a single-network (SN) structure, which shows certain limitations when encountering external environments with high loads and large deformations. In this paper, sodium alginate (SA) was introduced into the PAA-LCNF hydrogel network to prepare a double-network (DN) hydrogel structure of the SA-Ca2+ and PAA-LCNF through a two-step process...
December 28, 2023: Polymers
https://read.qxmd.com/read/38199109/covalent-organic-framework-sodium-alginate-ca-2-polyacrylic-acid-composite-beads-for-convenient-dispersive-solid-phase-extraction-of-neonicotinoid-insecticides-in-fruit-and-vegetables
#6
JOURNAL ARTICLE
Ling-Zhi Liu, Rui Zhou, Yong-Li Li, Yue-Hong Pang, Xiao-Fang Shen, Jun Liu
Neonicotinoids, the fastest-growing class of insecticides, have posed a multi-media residue problem with adverse effects on environment, biodiversity and human health. Herein, covalent organic framework-sodium alginate-Ca2+ -polyacrylic acid composite beads (CACPs), facilely prepared at room temperature, were used in convenient dispersive solid-phase extraction (dSPE) and combined with high-performance liquid chromatography (HPLC) for the detection of five neonicotinoid insecticides (thiamethoxam, acetamiprid, dinotefuran, clothianidin, imidacloprid)...
January 5, 2024: Food Chemistry
https://read.qxmd.com/read/38178849/a-significant-antibiofilm-and-antimicrobial-activity-of-chitosan-polyacrylic-acid-nanoparticles-against-pathogenic-bacteria
#7
JOURNAL ARTICLE
O'la Al-Fawares, Areen Alshweiat, Rozan O Al-Khresieh, Kawthar Z Alzarieni, Ayat Hussein B Rashaid
Chitosan is known to exert antimicrobial activity without the need for any chemical modification; however, new derivatives of chitosan can be created to target multi-drug resistant bacteria. In this study, chitosan (CS) was cross-linked with sodium tripolyphosphate to form nanoparticles, which were then coated with polyacrylic acid (PAA). The SEM images revealed that the CS-PAA nanoparticles had spherical shapes with smooth surfaces and the size of the dried nanoparticles was approximately 222 nm. Biofilm formation was significantly inhibited by 0...
January 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/38171688/sodium-carboxymethyl-cellulose-and-mxene-reinforced-multifunctional-conductive-hydrogels-for-multimodal-sensors-and-flexible-supercapacitors
#8
JOURNAL ARTICLE
Hongyan Yin, Fangfei Liu, Tursun Abdiryim, Jiaying Chen, Xiong Liu
With the growing demand for eco-friendly materials in wearable smart electronic devices, renewable, biocompatible, and low-cost hydrogels based on natural polymers have attracted much attention. Cellulose, as one of the renewable and degradable natural polymers, shows great potential in wearable smart electronic devices. Multifunctional conductive cellulose-based hydrogels are designed for flexible electronic devices by adding sodium carboxymethyl cellulose and MXene into polyacrylic acid networks. The multifunctional hydrogels possess excellent mechanical property (stress: 310 kPa; strain: 1127 %), toughness (206...
March 1, 2024: Carbohydrate Polymers
https://read.qxmd.com/read/38163726/improving-the-texture-attributes-of-squid-meat-sthenoteuthis-oualaniensis-with-slight-oxidative-and-phosphate-curing-treatments
#9
JOURNAL ARTICLE
Jiangxiang Wang, Zheng Xu, Wei Lu, Xuxia Zhou, Shulai Liu, Shichen Zhu, Yuting Ding
This study aimed to improve the pasty texture of squid meat by oxidative and phosphate curing (OPC) treatment, and elucidate the underlying mechanism. The shear force, springiness, weight gain, water-holding capacity (WHC), color and sensory evaluation of squid meat samples treated with a mild OPC approach (OPC_2, 10 mM H2 O2 solution with complex phosphate solution) were significantly improved. However, the samples subjected to over-oxidized (20 and 30 mM H2 O2 solution with complex phosphate solution) treatment did not obtain favorable outcomes...
January 2024: Food Research International
https://read.qxmd.com/read/38068165/effect-of-composition-on-the-physicochemical-properties-of-cross-linked-poly-sodium-acrylate-sodium-silicate-hydrogels
#10
JOURNAL ARTICLE
Joanna Mastalska-Popławska, Łukasz Wójcik, Piotr Izak, Damian Konaszewski
The paper presents the results of research on the influence of the components of composition on the physicochemical properties of cross-linked poly(sodium acrylate)/sodium silicate hydrogels. The results of the rheological measurements showed that an increasing share of polyacrylate in the sample causes a shift of the cross-over point towards longer times and improves mechanical properties. In turn, increasing the share of sodium silicate has a positive effect on extending the fire insulation time (I). TG/DSC analysis indicated that if the sample contained more than 50 wt...
November 29, 2023: Materials
https://read.qxmd.com/read/38054367/the-influence-of-selected-polymers-on-the-surface-tension-of-solutions-developed-for-the-preparation-of-eye-drops
#11
JOURNAL ARTICLE
Monika Gasztych, Katarzyna Burdzy, Arleta Dołowacka-Jóźwiak, Witold Musiał
BACKGROUND: Many substances are used to increase the viscosity of eye drops and reduce their surface tension. Their function is to prolong the persistence of the product on the surface of the eyeball and to increase the bioavailability of the pharmacologically active ingredient. OBJECTIVES: To investigate the surface tension of substances added to the eye drops, with the main aim of modulating properties of the preparation. MATERIAL AND METHODS: Five substances contained in solutions proposed for the development of eye drops were studied: sodium hyaluronate macromolecular (H-Na W), sodium hyaluronate ultramolecular (H-Na UM), hyaluronic acid 4% (K-H), methylcellulose (MC), and polyacrylic acid (PA)...
December 6, 2023: Polimery W Medycynie
https://read.qxmd.com/read/38006795/preparation-of-high-strength-self-healing-conductive-hydrogel-based-on-polysaccharide-and-its-application-in-sensor
#12
JOURNAL ARTICLE
Junxiao Wang, Amatjan Sawut, Rena Simayi, Huijun Song, Xueying Jiao
The development of cost-effective, eco-friendly conductive hydrogels with excellent mechanical properties, self-healing capabilities, and non-toxicity holds immense significance in the realm of biosensors. The biosensors demonstrate promising applications in the fields of biomedical engineering and human motion detection. A unique double-network hydrogel was prepared through physical-chemical crosslinking using chitosan (CS), polyacrylic acid (AA), and sodium alginate (SA) as raw materials. The prepared double-network hydrogels exhibited exceptional mechanical properties, as well as self-healing and conductive capabilities...
November 22, 2023: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/37998952/preparation-and-performance-of-resin-gel-rubber-expandable-lost-circulation-material-blend
#13
JOURNAL ARTICLE
Jinzhi Zhu, Erbiao Lou, Shaojun Zhang, Haiying Lu, Ziwu Wang
Aiming at the complex strata, lost circulation often occurs. and lost circulation control becomes a difficult issue. A drilling fluid loss accident delays the drilling progress and even causes major economic losses. If we take a self-made sodium polyacrylate grafting and modify a starch water absorbent resin, using an amphiphilic compatibilizer as raw material through mechanical blending and chemical compatibilization, we can synthesize a resin-rubber blend swelling lost circulation material. This material presents a good resistance to anti-high-temperature performance, but the quality declines while the temperature is higher than 363 °C, and with the increasing temperature, the water-swelling expansion ratio becomes higher...
October 30, 2023: Gels
https://read.qxmd.com/read/37976748/boosting-the-sodium-storage-performance-of-iron-selenides-by-a-synergetic-effect-of-vacancy-engineering-and-spatial-confinement
#14
JOURNAL ARTICLE
Peng Wang, Yuxiang Chen, Xiangyue Liao, Qiaoji Zheng, Ruyi Zhao, Kwok-Ho Lam, Dunmin Lin
Recently, iron selenides have been considered as one of the most promising candidates for the anodes of sodium-ion batteries (SIBs) due to their cost-effectiveness and high theoretical capacity; however, their practical application is limited by poor conductivity, large volume variation and slow reaction kinetics during electrochemical reactions. In this work, spatially dual-carbon-confined VSe -Fe3 Se4-x Sx /FeSe2-x Sx nanohybrids with abundant Se vacancies (VSe -Fe3 Se4-x Sx /FeSe2-x Sx @NSC@rGO) are constructed via anion doping and carbon confinement engineering...
November 13, 2023: Journal of Colloid and Interface Science
https://read.qxmd.com/read/37952506/fabrication-of-hydrophilic-polymer-hybrid-octacalcium-phosphate-blocks-under-wet-condition-based-on-cement-setting-reactions
#15
JOURNAL ARTICLE
Yuki Sugiura, Etsuko Yamada, Masanori Horie
Bioceramics, while offering excellent biocompatibility, are often compromised by their fragility and brittleness, especially under wet conditions. Even though recent hybrid processes combining biocompatible polymers and bioceramics have shown promise, complete mitigation of these challenges remains elusive. In this research, a biomimetic process was employed to mimic the structure of biological bone tissue. This led to the development of block materials composed of octacalcium phosphate (OCP) and sodium polyacrylic acid (PAA-Na) that display flexibility and resilience in wet conditions...
November 7, 2023: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/37872249/atmospheric-moisture-induced-polyacrylate-hydrogels-for-hybrid-passive-cooling
#16
JOURNAL ARTICLE
Roisul Hasan Galib, Yanpei Tian, Yue Lei, Saichao Dang, Xiaole Li, Arief Yudhanto, Gilles Lubineau, Qiaoqiang Gan
Heat stress is being exacerbated by global warming, jeopardizing human and social sustainability. As a result, reliable and energy-efficient cooling methods are highly sought-after. Here, we report a polyacrylate film fabricated by self-moisture-absorbing hygroscopic hydrogel for efficient hybrid passive cooling. Using one of the lowest-cost industrial materials (e.g., sodium polyacrylate), we demonstrate radiative cooling by reducing solar heating with high solar reflectance (0.93) while maximizing thermal emission with high mid-infrared emittance (0...
October 23, 2023: Nature Communications
https://read.qxmd.com/read/37870942/porphyrin-regulated-heterostructured-hydrogel-ionic-diode-with-a-high-rectification-ratio-and-output-voltage
#17
JOURNAL ARTICLE
Yanqing Wei, Yize Zhao, Yue Liu, Na Luo, Zunchang Gao, Pu Hou, Yang Liu, Yanhua Zhang, Pengfei Huo
Nanochannel ionic diodes require extremely complex and expensive fabrication processes. Polyelectrolyte ionic diodes attracted widespread attention among ionic rectification systems due to their simplicity of development and the ability to break the size limits of the nanochannel. However, enhancement of their rectification ratio is still in the exploratory stage. In this study, chitosan (CS) hydrogels and sodium polyacrylate (PAAs) hydrogels were prepared as the substrates for the heterostructured ionic diodes...
October 23, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/37848001/film-forming-polymers-for-inhibition-of-hydroxyapatite-dissolution-a-screening-study
#18
JOURNAL ARTICLE
Letícia Oba Sakae, Taiana Paola Prado, Sávio José Cardoso Bezerra, Samira Helena Niemeyer, Alessandra Buhler Borges, Thiago Saads Carvalho, Tais Scaramucci
The aim of this study was to evaluate the effect of film-forming polymer solutions of different concentrations and pH values, either associated or not with sodium fluoride (F; 225 ppm F-), when applied during the initial stage of salivary pellicle formation, to prevent the dissolution of hydroxyapatite (HA), which was determined by the pH-stat method. Polyacrylic acid (PA), Chitosan, Sodium linear polyphosphate (LPP), Polyvinyl methyl ether/maleic anhydride (PVM/MA) and Propylene glycol alginate (PGA) were tested in three concentrations (lower, medium, higher), two pH values (native or adjusted) and either associated or not with F...
October 17, 2023: Caries Research
https://read.qxmd.com/read/37836042/durable-polyacrylic-siloxane-silica-coating-for-the-protection-of-cast-alsi7mg0-3-alloy-against-corrosion-in-chloride-solution
#19
JOURNAL ARTICLE
Peter Rodič, Barbara Kapun, Ingrid Milošev
This study presented a novel corrosion protective coating based on polyacrylic/siloxane-silica (PEHA-SS) deposited on lightweight cast aluminium alloy AlSi7Mg0.3. The synthesis of PEHA-SS comprises organic monomer 2-ethylhexyl acrylate and organically modified silane 3-(trimethoxysilyl)propyl methacrylate as well as an inorganic silane, tetraethyl orthosilicate. The steps during the synthesis process were monitored using real-time infrared spectroscopy. The coating deposited onto the AlSi7Mg0.3 surface was characterised using various techniques, including infrared spectroscopy, 3D contact profilometry, and scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy...
October 4, 2023: Polymers
https://read.qxmd.com/read/37835908/understanding-the-behavior-of-sodium-polyacrylate-in-suspensions-of-silica-and-monovalent-salts
#20
JOURNAL ARTICLE
Gonzalo R Quezada, Francisco Retamal, Matías Jeldres, Ricardo I Jeldres
This study investigated the interaction of monovalent cations with different sizes on quartz surfaces and the rheological impact that this causes in concentrated suspensions when subjected to the action of a rheological modifier, in this case, sodium polyacrylate (NaPA). Yield stress was determined using a rheometer with a vane-in-cup configuration to establish the relationship between shear stress and strain. Experiments were carried out in LiCl, NaCl, KCl, and CsCl solutions. The results show that the yield stress increases following the order Li < Na < K < Cs in the absence of PAA...
September 22, 2023: Polymers
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