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https://www.readbyqxmd.com/read/29222562/dysphagia-and-pharyngeal-obstruction-in-a-nonsmoker
#1
Brian A Nuyen, Gerald Berry, Uchechukwu Megwalu
No abstract text is available yet for this article.
December 7, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29218488/effect-of-body-position-on-pharyngeal-swallowing-pressures-using-high-resolution-manometry
#2
Sarah P Rosen, Suzan M Abdelhalim, Corinne A Jones, Timothy M McCulloch
The effect of body position and gravitational pull on the complex pressure-driven process of pharyngeal swallowing remains unknown. Using high-resolution manometry (HRM), this study aims to identify positional adaptations of pharyngeal physiology by evaluating swallowing pressure patterns in a series of inverted body positions. Ten healthy adults each underwent swallowing tasks with pharyngeal HRM at six body positions using an inversion table (0°[upright], 45°, 90°[supine], 110°, 135°, and 180°[fully inverted])...
December 7, 2017: Dysphagia
https://www.readbyqxmd.com/read/29218415/timing-of-cortical-activation-during-spontaneous-swallowing
#3
Erin Kamarunas, Rachel Mulheren, Katie Palmore, Christy Ludlow
Saliva accumulation in the oropharynx generates an automatic pattern of swallowing in the brainstem in animals. Previous fMRI studies have found that spontaneous saliva and water swallows in humans evoked activation following swallow onset in both precentral motor and postcentral somatosensory cortical regions. Using event-related averaging of continuous functional near infrared spectroscopy (fNIRS), we examined cortical hemodynamic responses (HDR) from 5 s before to 35 s after spontaneous reflexive saliva swallow onset in the lateral postcentral somatosensory and precentral motor regions in both hemispheres in healthy volunteers...
December 7, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29217897/long-lasting-dysphagia-developing-after-thoracotomy-for-pulmonary-resection-a-case-series
#4
Ikuno Ito, Kohei Hamada, Hiroyuki Sato, Naoko Shindo
The purpose of this study was to retrospectively evaluate the severity and the characteristics of dysphagia using videofluoroscopic swallowing studies (VFSS) in long-lasting dysphagia patients developing after thoracotomy performed for pulmonary resection. Eleven patients (10 men and 1 woman, average age 67 ± 6.6 years; the average operation time in the patients was 507 min) were selected from among patients who developed dysphagia after undergoing thoracotomy for pulmonary resection between January 2009 and December 2012...
December 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29217200/timing-is-everything-reiterative-wnt-bmp-and-ra-signaling-regulate-developmental-competence-during-endoderm-organogenesis
#5
Scott A Rankin, Kyle W McCracken, David M Luedeke, Lu Han, James M Wells, John M Shannon, Aaron M Zorn
A small number of signaling pathways are used repeatedly during organogenesis, and they can have drastically different effects on the same population of cells depending on the embryonic stage. How cellular competence changes over developmental time is not well understood. Here we used Xenopus, mouse, and human pluripotent stem cells to investigate how the temporal sequence of Wnt, BMP, and retinoic acid (RA) signals regulates endoderm developmental competence and organ induction, focusing on respiratory fate...
December 4, 2017: Developmental Biology
https://www.readbyqxmd.com/read/29212040/molecular-and-cellular-organization-of-taste-neurons-in-adult-drosophila-pharynx
#6
Yu-Chieh David Chen, Anupama Dahanukar
The Drosophila pharyngeal taste organs are poorly characterized despite their location at important sites for monitoring food quality. Functional analysis of pharyngeal neurons has been hindered by the paucity of molecular tools to manipulate them, as well as their relative inaccessibility for neurophysiological investigations. Here, we generate receptor-to-neuron maps of all three pharyngeal taste organs by performing a comprehensive chemoreceptor-GAL4/LexA expression analysis. The organization of pharyngeal neurons reveals similarities and distinctions in receptor repertoires and neuronal groupings compared to external taste neurons...
December 5, 2017: Cell Reports
https://www.readbyqxmd.com/read/29206831/prognostic-value-of-aldh2-polymorphism-for-patients-with-oropharyngeal-cancer-in-a-japanese-population
#7
Hirotaka Shinomiya, Hitomi Shinomiya, Mie Kubo, Yuki Saito, Masafumi Yoshida, Mizuo Ando, Masanori Teshima, Naoki Otsuki, Naomi Kiyota, Ryohei Sasaki, Ken-Ichi Nibu
BACKGROUND: Half of Japanese possess a polymorphism of aldehyde dehydrogenase 2(ALDH2), while few white individuals possess this mutation. The purpose of this study was to investigate the possibility of ALDH2 polymorphism as a prognostic factor for oropharyngeal cancer (OPC) among Japanese population. METHODS: We analyzed 82 Japanese patients with OPC treated between 2006 and 2011. The median observation period was 50 months. P16-staining and ALDH2 polymorphisms were investigated...
2017: PloS One
https://www.readbyqxmd.com/read/29206327/pharyngeal-perforation-after-anterior-cervical-spine-surgery-treated-by-transoral-endoscopic-surgery
#8
Julio Rama-López, Meritxell Tomás-Fernandez, César García-Garza, Milton Martínez-Madrigal
BACKGROUND: Anterior cervical fixation has been used since 1967 for multiple pathologies like traumatism, compressive myelopathy, or spinal infections. METHODS: We report the case of a patient who had undergone cervical spine surgery 10 years previously and presented to our clinic with a pharyngeal fistula due to surgical screw displacement that was treated by transoral endoscopic surgery. RESULTS: The immediate postoperative period occurred without incidence and complete odynophagia resolution...
December 5, 2017: Head & Neck
https://www.readbyqxmd.com/read/29205391/association-of-palatine-tonsil-size-and-obstructive-sleep-apnea-in-adults
#9
Sebastian M Jara, Edward M Weaver
OBJECTIVE: The relationship between palatine tonsil (PT) size and obstructive sleep apnea (OSA) has not been well established in adults. The purpose of this study was to test the association between PT grade, PT volume, and OSA severity in U.S. adult patients. STUDY DESIGN: Cross-sectional study of all patients (age ≥ 18 years) who underwent pharyngeal surgery for OSA that included palatine tonsillectomy with tonsil volume measurement from January 2011 to June 2016...
December 5, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29205078/an-oral-pharyngeal-scope-for-objective-oropharyngeal-examination-a-new-device-for-oropharyngeal-study
#10
Koichi Tsunoda, Rika Kobayashi, Akiko Kada, Akiko M Saito, Fumiyuki Goto, Yoichiro Sugiyama, Yasuo Hisa, Kenji Kondo, Atsunobu Tsunoda, Keizo Horibe, Hayato Misawa, Toru Sasaki, Takanozawa Minako, Hiroshi Nishino
OBJECTIVE: There has been little progress in examination of the oropharynx with a light source such as electric light, a penlight, or a forehead mirror over the past 100 years. It is therefore necessary to develop methods to display and record oropharyngeal observations. METHOD: Since the aim of this study was to assess the safeness to use from the perspective of physicians, medical staffs, patients, and patients' families and usefulness of pharyngeal scope, the number of devices was limited, the number of patients was not set based on hypothetical statistical tests...
December 5, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29203159/long-term-follow-up-of-tonsillectomy-efficacy-in-children-with-pfapa-syndrome
#11
Ozturk Aktas, Hande Gurbuz Aytuluk, Sebla Kumas Caliskan, Omer Erdur, Ahmet Adnan Cirik
INTRODUCTION: The role of tonsillectomy in the periodic fever, aphthous stomatitis, pharyngitis, and adenitis, PFAPA syndrome, is controversial. Although some studies reported high success rates with tonsillectomy, further investigations are needed with larger numbers of patients. OBJECTIVE: To seek the long-term outcomes of tonsillectomy in PFAPA syndrome. METHODS: Case series; multi-center study. The study comprised 23 patients with PFAPA syndrome who underwent surgery (tonsillectomy with or without adenoidectomy) between January 2009 and November 2014...
November 21, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29202671/natural-lymphatic-atypical-actinobacillosis-in-cattle-caused-by-actinobacillus-lignieresii
#12
Rubén D Caffarena, Ana Rabaza, Laura Casaux, Melissa Macías Rioseco, Carlos O Schild, Cecilia Monesiglio, Martín Fraga, Federico Giannitti, Franklin Riet-Correa
Bovine actinobacillosis is typically characterized by pyogranulomatous glossitis (wooden tongue). The involvement of other tissues, generally the skin or lymph nodes, has been regarded as atypical or cutaneous. We describe herein 2 outbreaks of actinobacillosis affecting primarily the lymph nodes of the head and neck. The disease affected 40 of 540 lactating cows in a dairy herd and 5 of 335 two-y-old steers in a beef herd. Multiple or single, occasionally ulcerated nodules were observed in the region of the mandible, neck, and shoulder, including the parotid, submandibular, retropharyngeal, and prescapular lymph nodes...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29201816/quantitative-analysis-of-swallowing-function-between-dysphagia-patients-and-healthy-subjects-using-high-resolution-manometry
#13
Chul-Hyun Park, Don-Kyu Kim, Yong-Taek Lee, Youbin Yi, Jung-Sang Lee, Kunwoo Kim, Jung Ho Park, Kyung Jae Yoon
Objective: To compare swallowing function between healthy subjects and patients with pharyngeal dysphagia using high resolution manometry (HRM) and to evaluate the usefulness of HRM for detecting pharyngeal dysphagia. Methods: Seventy-five patients with dysphagia and 28 healthy subjects were included in this study. Diagnosis of dysphagia was confirmed by a videofluoroscopy. HRM was performed to measure pressure and timing information at the velopharynx (VP), tongue base (TB), and upper esophageal sphincter (UES)...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29201389/the-feasibility-of-assessing-swallowing-physiology-following-prolonged-intubation-after-cardiovascular-surgery
#14
Stacey A Skoretz, Terrence M Yau, John T Granton, Rosemary Martino
Background: Dysphagia following prolonged intubation after cardiovascular (CV) surgery is common occurring in 67% of patients; however, this population's swallowing physiology has never been prospectively evaluated using standardized methods. Hence, prior to conducting a larger study, our primary objective was to determine the feasibility of assessing swallowing physiology using instrumentation and validated interpretation methods in cardiovascular surgical patients following prolonged intubation...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29201038/anatomical-alterations-in-plant-tissues-induced-by-plant-parasitic-nematodes
#15
REVIEW
Juan E Palomares-Rius, Carolina Escobar, Javier Cabrera, Alessio Vovlas, Pablo Castillo
Plant-parasitic nematodes (PPNs) interact with plants in different ways, for example, through subtle feeding behavior, migrating destructively through infected tissues, or acting as virus-vectors for nepoviruses. They are all obligate biotrophic parasites as they derive their nutrients from living cells which they modify using pharyngeal gland secretions prior to food ingestion. Some of them can also shield themselves against plant defenses to sustain a relatively long lasting interaction while feeding. This paper is centered on cell types or organs that are newly induced in plants during PPN parasitism, including recent approaches to their study based on molecular biology combined with cell biology-histopathology...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29200894/potential-for-severe-airway-obstruction-from-pediatric-retropharyngeal-abscess
#16
Michelle M LeRiger, Veronica Miler, Joseph D Tobias, Vidya T Raman, Charles A Elmaraghy, Kris R Jatana
Retropharyngeal abscesses in the pediatric population can cause severe respiratory distress. We report a rare case of significant airway obstruction in a 14-month-old patient requiring rapid, emergent tracheotomy after attempts at endotracheal intubation by an experienced airway surgeon were unsuccessful. The patient was diagnosed with streptococcal pharyngitis 9 days prior to presentation to our facility and was being treated with amoxicillin. Prompt diagnosis, communication, and appropriate multidisciplinary airway management can lead to successful outcomes even in these severe cases...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29200373/retropharyngeal-dissection-by-parker-flex-tip-nasal-endotracheal-tube
#17
Makoto Terumitsu, Mikiko Hirahara, Kenji Seo
Possible complications of nasotracheal intubation include injury to the nasal or pharyngeal mucosa. Dissection of the retropharyngeal tissue by the endotracheal tube is one of the rarer of the more severe complications. Previous studies have indicated that the Parker Flex-Tip (PFT) tracheal tube (Parker Medical, Highlands Ranch, Colo) reduces the incidence of mucosal injury. We experienced a case involving inadvertent retropharyngeal placement of a PFT tube in a 29-year-old patient during nasotracheal intubation under general anesthesia for elective dental treatment...
2017: Anesthesia Progress
https://www.readbyqxmd.com/read/29198376/short-and-long-term-changes-of-the-pharyngeal-airway-after-surgical-mandibular-advancement-in-class-ii-patients-a-three-dimensional-retrospective-study
#18
Oliver Ristow, Thomas Rückschloß, Moritz Berger, Thekla Grötz, Steffen Kargus, Johannes Krisam, Robin Seeberger, Michael Engel, Jürgen Hoffmann, Christian Freudlsperger
PURPOSE: To evaluate the short- and long-term impact of mandibular-only advancement on pharyngeal airway space (PAS) changes by using cone-beam computed tomography (CBCT) and a new segmentation software. Furthermore, to determine whether a correlation exists between forward movement and PAS gain. MATERIALS AND METHODS: A retrospective evaluation of a homogeneous cohort of Class II patients who had undergone mandibular-only advancement was performed. Pre- (T0), post- (T1), and 1-year post-operative (T2) CBCT scans were obtained in each case, and the changes in PAS parameters (volume and smallest cross-sectional area) were compared with new segmentation software...
November 6, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29198179/screening-for-chlamydia-trachomatis-and-neisseria-gonorrhoeae-infection-among-asymptomatic-men-who-have-sex-with-men-in-bangkok-thailand
#19
Sarika Pattanasin, Eileen F Dunne, Punneeporn Wasinrapee, Jaray Tongtoyai, Wannee Chonwattana, Anuwat Sriporn, Pikunchai Luechai, Philip A Mock, Anupong Chitwarakorn, Timothy H Holtz, Marcel E Curlin
We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs)...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29197986/relationships-between-mri-fat-distributions-and-sleep-apnea-and-obesity-hypoventilation-syndrome-in-very-obese-patients
#20
C D Turnbull, S H Wang, A R Manuel, B T Keenan, A G McIntyre, R J Schwab, J R Stradling
PURPOSE: Obesity is associated with both obstructive sleep apnea (OSA) and obesity hypoventilation. Differences in adipose tissue distribution are thought to underlie the development of both OSA and hypoventilation. We explored the relationships between the distribution of upper airway, neck, chest, abdominal and muscle fat in very obese individuals. METHODS: We conducted a cross-sectional cohort study of individuals presenting to a tertiary sleep clinic or for assessment for bariatric surgery...
December 2, 2017: Sleep & Breathing, Schlaf & Atmung
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