keyword
MENU ▼
Read by QxMD icon Read
search

botanical

keyword
https://www.readbyqxmd.com/read/28812892/designer-extracts-as-tools-to-balance-estrogenic-and-chemopreventive-activities-of-botanicals-for-women-s-health
#1
Birgit M Dietz, Shao-Nong Chen, René F Ramos Alvarenga, Huali Dong, Dejan Nikolić, Martin Biendl, Richard B van Breemen, Judy L Bolton, Guido F Pauli
Botanical dietary supplements contain multiple bioactive compounds that target numerous biological pathways. The lack of uniform standardization requirements is one reason that inconsistent clinical effects are reported frequently. The multifaceted biological interactions of active principles can be disentangled by a coupled pharmacological/phytochemical approach using specialized ("knock-out") extracts. This is demonstrated for hops, a botanical for menopausal symptom management. Employing targeted, adsorbent-free countercurrent separation, Humulus lupulus extracts were designed for pre- and postmenopausal women by containing various amounts of the phytoestrogen 8-prenylnaringenin (8-PN) and the chemopreventive constituent xanthohumol (XH)...
August 16, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28809420/rapid-identification-of-%C3%AE-glucosidase-inhibitors-from-dioscorea-opposita-thunb-peel-extract-by-enzyme-functionalized-fe3o4-magnetic-nanoparticles-coupled-with-hplc-ms-ms
#2
Songsong Zhang, Dandan Wu, Huan Li, Jinhua Zhu, Weiping Hu, Minghua Lu, Xiuhua Liu
Dioscorea opposita Thunb, commonly known as "yam" that has a long dietary therapy history for diabetes, is widely consumed as a botanical dietary supplement and widely cultivated in China. In this work, a method for rapid screening of α-glucosidase inhibitors from Dioscorea opposita Thunb peel extract was developed using α-glucosidase functionalized magnetic nanoparticles (αG-MNPs) as a solid phase extraction absorbent in combination with high performance liquid chromatography-mass spectrometry (HPLC-MS)...
August 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28808376/isolation-of-abscisic-acid-from-korean-acacia-honey-with-anti-helicobacter-pylori-activity
#3
SeGun Kim, InPyo Hong, SoonOk Woo, HyeRi Jang, SokCheon Pak, SangMi Han
BACKGROUND: Helicobacter pylori (H. pylori) is linked to the development of the majority of peptic ulcers and some types of gastric cancers, and its antibiotic resistance is currently found worldwide. OBJECTIVE: This study is aimed at evaluating the anti-H. pylori activity of Korean acacia honey and isolating the related active components using organic solvents. MATERIAL AND METHODS: The crude acacia honey was extracted with n-hexane, dichloromethane, ethyl acetate (EtOAc), and n-butanol...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28807848/hydroalcoholic-extract-from-bark-of-persea-major-meisn-l-e-kopp-lauraceae-exerts-antiulcer-effects-in-rodents-by-the-strengthening-of-the-gastric-protective-factors
#4
Lincon Bordignon Somensi, Thaise Boeing, Benhur Judah Cury, Viviane Miranda Bispo Steimbach, Rivaldo Niero, Lauro Mera de Souza, Luisa Mota da Silva, Sérgio Faloni de Andrade
ETHOPHARMACOLOGICAL RELEVANCE: The Persea major (Meisn.) L.E. Kopp (Lauraceae) (botanical synonym: Persea pyrifolia (D. Don) Spreng, Persea pyrifolia Nees and Mart., Persea cordata var. major (Meisn.) Mez and Persea willdenovii Kosterm) is a medicinal plant native in the south of Brazil, where is popularly known as Pau de Andrade, Maçaranduba or Abacate-do-Mato. Its barks are commonly used to prepare an infusion which is administered orally or topically to treat ulcers and wounds, respectively...
August 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28806514/phenolic-compounds-profiling-of-virgin-olive-oils-from-different-varieties-cultivated-in-mendoza-argentina-by-using-liquid-chromatography-mass-spectrometry
#5
R P Monasterio, L Olmo-García, A Bajoub, A Fernandez-Gutierrez, A Carrasco-Pancorbo
The aim of this work was to achieve a preliminary characterization of the profile of the phenolic fraction of virgin olive oils (VOOs) from Maipú (Mendoza, Argentina). Thus, 25 commercial VOO samples from Arauco, Arbequina, Picual, Frantoio, Changlot, Empeltre, Nevadillo, Manzanilla and Coratina (both monovarietals and blends) were analyzed using LC-ESI-QTOF MS and LC-ESI-IT MS for identification and quantification purposes, respectively. A rapid LC method (15 min) accomplished quantitative information about a total of 40 phenolic compounds, including secoiridoid derivatives, which have not been evaluated before in samples coming from the sub-region so-called Maipú (Mendoza province, Argentina)...
August 14, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28804535/hongjingtian-injection-attenuates-myocardial-oxidative-damage-via-promoting-autophagy-and-inhibiting-apoptosis
#6
Shujing Zhang, Ling Zhang, Han Zhang, Guanwei Fan, Jiuwen Qiu, Zongbao Fang, Haibo Wu, Yi Wang, Xiaoping Zhao
Natural products with antioxidative activities are widely applied to prevent and treat various oxidative stress related diseases, including ischemic heart disease. However, the cellular and molecular mechanisms of those therapies are still needed to be illustrated. In this study, we characterized the cardioprotective effects of Hongjingtian Injection (HJT), an extensively used botanical drug for treating coronary heart disease. The H/R-induced profound elevation of oxidative stress was suppressed by HJT. HJT also attenuates oxidative injury by promoting cell viability, intracellular ATP contents, and mitochondrial oxygen consumption...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28801042/triacylglycerols-tags-in-edible-oils-determination-characterization-quantitation-chemometric-approach-and-evaluation-of-adulterations
#7
REVIEW
Serena Indelicato, David Bongiorno, Rosa Pitonzo, Vita Di Stefano, Valentina Calabrese, Sergio Indelicato, Giuseppe Avellone
Vegetable oils are a dietary source of lipids that constitute an essential component of a healthy diet. The commonly used vegetable oils differ significantly for their triacylglycerol (TAG) profile. TAGs represent the principal components of oils and may contain different fatty acids (FA) esterified with glycerol leading to several positional isomers. To differentiate individual TAGs species in edible oils, advanced analysis systems and innovative methods are therefore required. TAGs can be considered as good fingerprints for quality control and many studies have been performed to develop rapid and low cost analytical methods to determinate the authenticity, origin and eventually evidence frauds or adulterations...
August 2, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28800099/portuguese-honeys-from-different-geographical-and-botanical-origins-a-4-year-stability-study-regarding-quality-parameters-and-antioxidant-activity
#8
Sonia Soares, Diana Pinto, Francisca Rodrigues, Rita C Alves, M Beatriz P P Oliveira
Portuguese honeys (n = 15) from different botanical and geographical origins were analysed regarding their quality parameters (diastase activity, hydroxymethylfurfural content, moisture and pH), colour (L*, a*, b*) and antioxidant profile (total phenolics content, total flavonoids content, DPPH• scavenging activity, and ferric reducing power). The samples were analysed fresh and after 4-years of storage (at 25 °C and protected from light). The hydroxymethylfurfural content and diastase activity of the fresh samples were in accordance with the recommended values described in the legislation...
August 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28799721/bioassay-guided-isolation-of-potent-aphicidal-erythrina-alkaloids-against-aphis-gossypii-from-the-seed-of-erythrina-crista-galli-l
#9
Wang Delong, Xie Na, Shandong Yi, Chuanyuan Liu, Hui Jiang, Ma Zhiqing, Feng Juntao, He Yan, Zhang Xing
BACKGROUND: Cotton aphid (Aphis gossypii Glover) is one of the most invasive pests to cotton. Many botanical phytochemicals have a long history as a source of insecticides, and templates for new insecticides. This study was undertaken to isolate aphicidal compounds from the seeds of Erythrina crista-galli L. following the bioassay-guided isolation method. RESULTS: Three novel and eleven known Erythrina alkaloids were isolated. Compounds erysodine (9), erysovine (10), erysotrine (8) and erythraline (11) showed moderate to excellent aphicidal activity with LD50 of 7...
August 11, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28796271/nonergodicity-parameters-of-confined-hard-sphere-glasses
#10
Suvendu Mandal, Simon Lang, Vitalie Boţan, Thomas Franosch
Within a recently developed mode-coupling theory for fluids confined to a slit we elaborate numerical results for the long-time limits of suitably generalized intermediate scattering functions. The theory requires as input the density profile perpendicular to the plates, which we obtain from density functional theory within the fundamental-measure framework, as well as symmetry-adapted static structure factors, which can be calculated relying on the inhomogeneous Percus-Yevick closure. Our calculations for the nonergodicity parameters for both the collective as well as for the self motion are in qualitative agreement with our extensive event-driven molecular dynamics simulations for the intermediate scattering functions for slightly polydisperse hard-sphere systems at high packing fraction...
August 10, 2017: Soft Matter
https://www.readbyqxmd.com/read/28796173/effects-of-vegetables-on-cardiovascular-diseases-and-related-mechanisms
#11
REVIEW
Guo-Yi Tang, Xiao Meng, Ya Li, Cai-Ning Zhao, Qing Liu, Hua-Bin Li
Epidemiological studies have shown that vegetable consumption is inversely related to the risk of cardiovascular diseases. Moreover, research has indicated that many vegetables like potatoes, soybeans, sesame, tomatoes, dioscorea, onions, celery, broccoli, lettuce and asparagus showed great potential in preventing and treating cardiovascular diseases, and vitamins, essential elements, dietary fibers, botanic proteins and phytochemicals were bioactive components. The cardioprotective effects of vegetables might involve antioxidation; anti-inflammation; anti-platelet; regulating blood pressure, blood glucose, and lipid profile; attenuating myocardial damage; and modulating relevant enzyme activities, gene expression, and signaling pathways as well as some other biomarkers associated to cardiovascular diseases...
August 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28793900/botanical-ethnoveterinary-therapies-used-by-agro-pastoralists-of-fafan-zone-eastern-ethiopia
#12
Teka Feyera, Endalkachew Mekonnen, Befekadu Urga Wakayo, Solomon Assefa
BACKGROUND: In Ethiopia, plant based remedies are still the most important and sometimes the only source of therapeutics in the management of livestock diseases. However, documentation of this indigenous knowledge of therapeutic system still remains at a minimum level. The aim of this study was, thus, to document the traditional knowledge of botanical ethnoveterinary therapies in the agro-pastoral communities of Fafan Zone, Eastern Ethiopia. METHODS: The study employed a cross-sectional participatory survey...
August 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28792522/biochemical-characterization-and-anti-inflammatory-properties-of-an-isothiocyanate-enriched-moringa-moringa-oleifera-seed-extract
#13
Asha Jaja-Chimedza, Brittany L Graf, Charlotte Simmler, Youjin Kim, Peter Kuhn, Guido F Pauli, Ilya Raskin
Moringa oleifera Lam. is a tropical plant, used for centuries as food and traditional medicine. The aim of this study was to develop, validate and biochemically characterize an isothiocyanate-enriched moringa seed extract (MSE), and to compare the anti-inflammatory effects of MSE-containing moringa isothiocyanate-1 (MIC-1) with a curcuminoid-enriched turmeric extract (CTE), and a material further enriched in its primary phytochemical, curcumin (curcumin-enriched material; CEM). MSE was prepared by incubating ground moringa seeds with water to allow myrosinase-catalyzed enzymatic formation of bioactive MIC-1, the predominant isothiocyanate in moringa seeds...
2017: PloS One
https://www.readbyqxmd.com/read/28789798/development-of-a-validated-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-method-for-determination-of-acid-diterpenes-in-copaifera-oleoresins
#14
Jonas Joaquim Mangabeira da Silva, Eduardo José Crevelin, Luiza Junqueira Carneiro, Hervé Rogez, Rodrigo Cassio Sola Veneziani, Sérgio Ricardo Ambrósio, Luiz Alberto Beraldo Moraes, Jairo Kenupp Bastos
Species of Copaifera genus (Fabaceae - Caesalpinoiodidaeae) produces an important commercial oleoresin that displays many medicinal properties. Copaifera oleoresins (COR) are composed mainly of a mixture of diterpenes and sequiterpenes, and the main reported acid diterpenes for this genus are kaurenoic, copalic, hardwickiic and polyaltic acids. An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for identification and quantification of nine acid diterpenes...
July 12, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28789524/glucuronidated-flavonoids-in-neurological-protection-structural-analysis-and-approaches-for-chemical-and-biological-synthesis
#15
Maite Docampo, Adiji Olubu, Xiaoqiang Wang, Giulio M Pasinetti, Richard Arthur Dixon
Both plant and mammalian cells express glucuronosyltransferases that catalyze glucuronidation of polyphenols such as flavonoids and other small molecules. Oral administration of select polyphenolic compounds leads to the accumulation of the corresponding glucuronidated metabolites at µM and sub-µM concentrations in the brain, associated with amelioration of a range of neurological symptoms. Determining the mechanisms whereby botanical extracts impact cognitive wellbeing and psychological resiliency will require investigation of the modes of action of the brain-targeted metabolites...
August 9, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28783246/the-effect-of-carabrone-on-mitochondrial-respiratory-chain-complexes-in-gaeumannomyces-graminis
#16
Mei Wang, Lanying Wang, Lirong Han, Xing Zhang, Juntao Feng
AIMS: To evaluate the effect of carabrone on mitochondrial respiratory chain complexes in Gaeumannomyces graminis to identify carabrone targets. METHODS AND RESULTS: The influence of carabrone on mitochondria in G. graminis mycelia was determined and the activity of complexes I-V, citrate synthase, and respiratory chain complexes I+III and II+III was evaluated following treatment with 30% effective concentration (EC30 ) as well as EC50 and EC70 of carabrone for 0, 6, 12 and 24 h...
August 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28774812/cytochrome-p450-inhibition-by-three-licorice-species-and-fourteen-licorice-constituents
#17
Guannan Li, Charlotte Simmler, Luying Chen, Dejan Nikolic, Shao-Nong Chen, Guido F Pauli, Richard B van Breemen
The potential of licorice dietary supplements to interact with drug metabolism was evaluated by testing extracts of three botanically identified licorice species (Glycyrrhiza glabra L., Glycyrrhiza uralensis Fish. ex DC. and Glycyrrhiza inflata Batalin) and 14 isolated licorice compounds for inhibition of 9 cytochrome P450 enzymes using a UHPLC-MS/MS cocktail assay. G. glabra showed moderate inhibitory effects against CYP2B6, CYP2C8, CYP2C9, and CYP2C19, and weak inhibition against CYP3A4 (testosterone). In contrast, G...
July 31, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28771010/systems-pharmacology-dissection-of-multi-scale-mechanisms-of-action-for-herbal-medicines-in-treating-rheumatoid-arthritis
#18
Jinghui Wang, Yan Li, Yinfeng Yang, Jian Du, Miaoqing Zhao, Feng Lin, Shuwei Zhang, Bin Wang
As a chronic inflammatory and angiogenic disease with increased morbidity and mortality, rheumatoid arthritis (RA) is characterized by the proliferation of synovial tissue and the accumulation of excessive mononuclear infiltration, which always results in the joint deformity, disability, and eventually the destruction of the bone and cartilage. Traditional Chinese Medicine (TCM), with rich history of proper effectiveness in treating the inflammatory joint disease containing RA, has long combated such illness from, actually, an integrative and holistic point of view...
August 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28769789/knowledge-of-medicinal-plants-for-children-diseases-in-the-environs-of-district-bannu-khyber-pakhtoonkhwa-kpk
#19
Shabnam Shaheen, Safdar Abbas, Javid Hussain, Fazal Mabood, Muhammad Umair, Maroof Ali, Mushtaq Ahmad, Muhammad Zafar, Umar Farooq, Ajmal Khan
Medicinal plants are important treasures for the treatment of different types of diseases. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants related to children disorders from district Bannu, Khyber Pakhtunkhwa (KPK) province of Pakistan. The information gathered was quantitatively analyzed using informant consensus factor, relative frequency of citation and use value method to establish a baseline data for more comprehensive investigations of bioactive compounds of indigenous medicinal plants specifically related to children disorders...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28764723/systematic-review-on-traditional-medicinal-plants-used-for-the-treatment-of-malaria-in-ethiopia-trends-and-perspectives
#20
REVIEW
Getachew Alebie, Befikadu Urga, Amha Worku
BACKGROUND: Ethiopia is endowed with abundant medicinal plant resources and traditional medicinal practices. However, available research evidence on indigenous anti-malarial plants is highly fragmented in the country. The present systematic review attempted to explore, synthesize and compile ethno-medicinal research evidence on anti-malarial medicinal plants in Ethiopia. METHODS: A systematic web search analysis and review was conducted on research literature pertaining to medicinal plants used for traditional malaria treatment in Ethiopia...
August 1, 2017: Malaria Journal
keyword
keyword
39894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"