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https://www.readbyqxmd.com/read/29337616/chronologic-analysis-of-gross-and-histologic-lesions-induced-by-field-strains-of-fadv-1-fadv-8b-and-fadv-11-in-six-week-old-chickens
#1
Penelope Steer-Cope, Jeanine Sandy, Denise O'Rourke, Peter Scott, Glenn Browning, Amir Noormohammadi
Inclusion body hepatitis (IBH) is a disease affecting broiler chicken flocks worldwide. Several serotypes of fowl adenovirus (FAdV) have been implicated in disease outbreaks, with and without immunosuppression as a predisposing factor. IBH usually occurs in flocks up to 30 days of age; it is seldom seen in older birds. The objective of this study was to determine whether the pathogenicity for older birds of three FAdV field strains, belonging to serotypes 1, 8b, and 11, in the absence of immunosuppressive factors, was akin to that for younger birds, and to establish an effective and economical disease model for assessing cross-protection between serotypes...
December 2017: Avian Diseases
https://www.readbyqxmd.com/read/29332630/effects-of-a-program-of-cognitive-behavioural-group-therapy-vestibular-rehabilitation-and-psychoeducational-explanations-on-patients-with-dizziness-and-no-quantified-balance-deficit-compared-to-patients-with-dizziness-and-a-quantified-balance-deficit
#2
D A Schmid, J H J Allum, M Sleptsova, S Gross, J Gaab, A Welge-Lüssen, R Schaefert, W Langewitz
BACKGROUND: We examined whether a program combining cognitive-behavioural therapy (CBT), vestibular rehabilitation (VR) and psychoeducation is equally effective in improving psychometric measures in patients with dizziness independent of a balance deficit. Measures of patients with dizziness only (DO) were compared to those of patients also having a quantified balance deficit (QBD). METHODS: 32 patients (23 female, 9 male) with persistent dizziness were analysed as 2 groups based on stance and gait balance control: those with QBD (pathological balance) or DO (normal balance)...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29330619/mr-arthrography-of-the-hip-diagnostic-performance-and-image-quality-of-3d-steady-state-free-precession-versus-2d-turbo-spin-echo-sequences
#3
Mareen Sarah Kraus, Mike Notohamiprodjo, Sasan Partovi, Ahmed Sobieh, Andrea Baur-Melnyk, Joerg Hausdorf, Ulrich Grosse
OBJECTIVE: To retrospectively compare the diagnostic performance of isotropic 3D steady-state free precession (3D-SSFP) sequences with 2D turbo spin-echo proton density-weighted fat-saturated (2D-TSE-PD fs) images in hip magnetic resonance arthrography; arthroscopy was a standard of reference. METHODS: Eighty-one patients with suspected labral tears who underwent hip MR arthrography (3-T scanner) were included. 2D-TSE-PD fs sequences were acquired in three planes and a singular sagittal 3D-SSFP...
January 12, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29325940/clinical-features-treatment-and-prognostic-factors-of-56-intracranial-and-intraspinal-clear-cell-meningiomas
#4
Xiaogang Tao, Jinqian Dong, Zonggang Hou, Shuyu Hao, Junting Zhang, Zhen Wu, Baiyun Liu
OBJECTIVE: Intracranial and intraspinal clear cell meningiomas (CCMs) are rarely reported because of their extremely low incidence, and the current understanding of CCM is poor. The purpose of this study was to analyze the incidence and the clinical, radiological, pathological, and prognostic features of intracranial and intraspinal CCMs. METHODS: Among 14310 cases of intracranial and intraspinal meningiomas that were surgically treated between 2006 and 2016 at Beijing Tian Tan Hospital, 56 were chosen for analysis and retrospectively reviewed...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29323741/stainless-steel-wear-debris-of-a-scoliotic-growth-guidance-system-has-little-local-and-systemic-effect-in-an-animal-model
#5
Vaneet Singh, Jeremy Rawlinson, Nadim Hallab
Options to treat early-onset scoliosis include guided-growth systems with sliding action between rods and pedicle screws. The wear was previously measured in an in vitro test, and in this in vivo rabbit model, we evaluated the local and systemic biological response to the stainless steel debris. Compared to the previous study, a relatively higher volume of representative wear particles with a median particle size of 0.84 µm were generated. Bolus dosages were injected into the epidural space at L4-L5 for a minimum of 36 rabbits across three treatment groups (negative control, 1...
January 11, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29317366/management-of-solitary-intracranial-metastases-of-differentiated-thyroid-carcinoma-11-pathologically-confirmed-cases-and-systematic-literature-review
#6
Mingyu Chen, Danqi Chen, Jian Xu, Ming Xu, Ping Zhong
BACKGROUND: Solitary intracranial metastases of differentiated thyroid carcinoma (DTC) are rare and the management is still controversial. This research is aim to seek for the suitable therapeutic methods of this disease. METHODS: We retrospectively studied 11 pathologically confirmed cases of solitary intracranial metastases of DTC in a single institution from January 2000 to December 2016 and systematically reviewed 52 cases of this disease out of 416 cases presented in the literature on Pubmed...
January 6, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29312599/histopathological-molecular-clinical-and-radiological-characterization-of-rosette-forming-glioneuronal-tumor-in-the-central-nervous-system
#7
Chenlong Yang, Jingyi Fang, Guang Li, Shaowu Li, Tingting Ha, Jiangfei Wang, Bao Yang, Jun Yang, Yulun Xu
Objective: A rosette-forming glioneuronal tumor (RGNT) is a rare entity originally described in the fourth ventricle. Recently, RGNTs occurring in extraventricular sites and those with malignant behaviors have been reported. The purpose of this study was to analyze the clinicoradiological and histopathological features, therapeutic strategies, and outcomes of RGNTs. Methods: We enrolled 38 patients diagnosed with RGNTs pathologically between August 2009 and June 2016...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29311434/suspected-lily-toxicosis-in-a-meerkat-suricata-suricatta-a-case-report
#8
Kiyokazu Ozaki, Masakazu Hirabayashi, Koji Nomura, Isao Narama
Lilies are considered nephrotoxic only to domestic cats, which belong to the family Felidae of the suborder Feliformia. However, a 7-month-old female meerkat, belonging to the family Herpestidae of the suborder Feliformia, presented with oliguria, seizure, tachypnea, self-biting, and nystagmus after it ingested lilies. The meerkat died approximately 40 hr after lily ingestion. Gross and histopathologic lesions consistent with acute renal failure were conspicuous in the animal. The renal lesions were acute tubular necrosis, corresponding to the typical pathological changes of lily toxicosis in cats...
January 4, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29309717/bucket-handle-tear-of-the-medial-meniscus-in-a-2-year-old-child
#9
Kyle Fink, Neil Kaushal, Jordan Gross, Himanshu Patel, Damon Delbello
Bucket-handle meniscal tears are extremely rare injuries in the pediatric population. Given the known sequelae of meniscal tears and the development of osteoarthritis, early diagnosis and treatment of pediatric meniscal tears are essential. The communication barrier between physicians and pediatric patients, however, creates difficulties in making the correct diagnosis of meniscal pathology. Providers should have a low threshold for obtaining further confirmatory advanced imaging if patients present with prolonged knee pain and swelling, with associated locking mechanical symptoms...
January 8, 2018: Orthopedics
https://www.readbyqxmd.com/read/29306321/relationship-between-the-extent-of-resection-and-the-survival-of-patients-with-low-grade-gliomas-a-systematic-review-and-meta-analysis
#10
Liang Xia, Chenyan Fang, Gao Chen, Caixing Sun
BACKGROUND: Surgical resection is necessary to conduct a pathological biopsy and to achieve a reduction of intracranial pressure in low-grade gliomas patients. This study aimed to determine whether a greater extent of resection would increase the overall 5-year and 10-year survival of patients with low-grade gliomas. METHODS: The studies addressing relationship between the extent of resection and the prognosis of low-grade gliomas updated until March 2017 were systematically searched in two databases (Pubmed and EMBASE)...
January 6, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29301464/intervertebral-disc-degeneration-in-warmblood-horses-morphology-grading-and-distribution-of-lesions
#11
Wilhelmina Bergmann, Niklas Bergknut, Stefanie Veraa, Andrea Gröne, Hans Vernooij, Inge D Wijnberg, Willem Back, Guy C M Grinwis
Equine intervertebral disc degeneration is thought to be rare and of limited clinical relevance, although research is lacking. To objectively assess pathological changes of the equine intervertebral disc and their clinical relevance, description of the normal morphology and a practical, biologically credible grading scheme are needed. The objectives of this study are to describe the gross and histological appearance of the equine intervertebral discs and to propose a grading scheme for macroscopic degeneration...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29300158/vaccination-of-sows-with-a-dendritic-cell-targeted-porcine-epidemic-diarrhea-virus-s1-protein-based-candidate-vaccine-reduced-viral-shedding-but-exacerbated-gross-pathological-lesions-in-suckling-neonatal-piglets
#12
Sakthivel Subramaniam, Danielle M Yugo, C Lynn Heffron, Adam J Rogers, Harini Sooryanarain, Tanya LeRoith, Christopher Overend, Dianjun Cao, Xiang-Jin Meng
Porcine epidemic diarrhea virus (PEDV) poses a serious threat to swine worldwide as evidenced by its recent introduction into the USA and the devastating economic impact it caused to the USA swine industry. Commercial vaccines against PEDV are available but their efficacies are inadequate. Therefore, vaccines with improved efficacy are needed to effectively control PEDV infections. We previously determined the immunogenicity of a novel dendritic cell (DC)-targeted PEDV S1 protein-based subunit vaccine in weaned piglets in which the PEDV antigen was targeted to DCs through a porcine Langerin-specific antibody...
January 4, 2018: Journal of General Virology
https://www.readbyqxmd.com/read/29297824/detection-of-mycobacterium-avium-subspecies-paratuberculosis-in-rock-hyraxes-procavia-capensis-imported-from-south-africa
#13
Kim Fechner, Jenny Schäfer, Pia Münster, Kerstin Ternes, Susanne Döring, Inger Völkel, Franz-Josef Kaup, Claus-Peter Czerny
Mycobacterium avium subspecies paratuberculosis (MAP) causes chronic, progressive, and consecutively fatal enteritis, especially in ruminants. MAP distribution among wildlife is not yet clear. In this study, three wild-born rock hyraxes ( Procavia capensis) had been imported from South Africa to a German zoological garden. During the quarantine period, four young animals were born. The wild-born animals showed symptoms of mild diarrhea shortly after their arrival in the zoological garden, but all routine parasitological and bacteriologic tests performed were negative...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29297809/congenital-nutritional-myodegeneration-white-muscle-disease-in-a-giraffe-giraffa-camelopardalis-calf
#14
Jan H Bos, Fokko C Klip, Marja J L Kik
It is well known that vitamin E and selenium deficiencies in domestic ruminants can lead to white muscle disease. After a clinically normal gestation period at Ouwehand Zoo in the Netherlands, a newborn giraffe ( Giraffa camelopardalis) calf showed clinical signs of white muscle disease almost immediately after birth. The calf was rejected by the mother and was euthanized 3 days later because of deterioration of clinical signs. At necropsy, pulmonary edema and pallor of skeletal and heart muscles was noted...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29291011/transferrin-receptor-1-upregulation-in-primary-tumor-and-downregulation-in-benign-kidney-is-associated-with-progression-and-mortality-in-renal-cell-carcinoma-patients
#15
Christopher J Greene, Kristopher Attwood, Nitika J Sharma, Kenneth W Gross, Gary J Smith, Bo Xu, Eric C Kauffman
The central dysregulated pathway of clear cell (cc) renal cell carcinoma (RCC), the von Hippel Lindau/hypoxia inducible factor-α axis, is a key regulator of intracellular iron levels, however the role of iron uptake in human RCC tumorigenesis and progression remains unknown. We conducted a thorough, large-scale investigation of the expression and prognostic significance of the primary iron uptake protein, transferrin receptor 1 (TfR1/CD71/TFRC), in RCC patients. TfR1 immunohistochemistry was performed in over 1500 cores from 574 renal cell tumor patient tissues (primary tumors, matched benign kidneys, metastases) and non-neoplastic tissues from 36 different body sites...
December 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/29290152/professor-samuel-david-gross-1805-1884-and-his-innovations-in-surgery-and-medicine
#16
Konstantinos Laios
Professor Samuel David Gross (1805-1884) is considered as one of the founders of American surgery. He was a skillful surgeon who could excellently perform a lithotomy, an amputation, and a cataract surgery. He introduced many new surgical techniques and designed new surgical and medical instruments. He expertise was not limited to surgery alone; he also published studies concerning internal medicine, pathology, experimental physiology, and pharmacology. His most important treatise was his 2-volume work, A System of Surgery, Pathological, Diagnostic, Therapeutic and Operative (1861), which was a standard reference book in surgery in the United States during the second half of 19th century...
December 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/29288693/mixed-adenoneuroendocrine-carcinoma-a-review-of-pathologic-characteristics
#17
Shayna A Brathwaite, Stephen M Smith, Lai Wai, Wendy Frankel, John Hays, Martha M Yearsley, Sherif Abdel-Misih
Mixed adenoneuroendocrine carcinoma (MANEC) is a rare pathologic entity defined as a tumor exhibiting both adenocarcinoma and neuroendocrine carcinoma components. Though uncommon, these tumors show aggressive behavior and generally portend a poor prognosis. This study seeks to further define clinicopathological characteristics of MANEC to aid in accurate diagnosis and properly direct clinical management. Thirty-four confirmed MANECs were identified in our twenty-five year retrospective review of cases arising in the gastrointestinal tract...
December 27, 2017: Human Pathology
https://www.readbyqxmd.com/read/29287801/subchronic-toxicity-and-genotoxicity-studies-of-antrodia-mushroom-%C3%AE-glucan-preparation
#18
S N Chen, C S Chang, S Chen, Madhu Soni
Antrodia cinnamomea is one of the most highly valued mushrooms utilized in traditional Taiwanese therapeutic practices. Its neutral monosaccharides (mannose, glucose and xylose) linked by a β-D-glucan chain have been claimed to be responsible for its health benefits. The objective of the present study was to investigate adverse effects, if any, of β-glucan (∼65% pure) from A. cinnamomea in subchronic toxicity and mutagenicity studies. In the subchronic toxicity study, Sprague Dawley rats (12/sex/group) were followed Organization for Economic Cooperation and Development (OECD) test guideline with Good Laboratory Practice (GLP) application, and were administered (gavage) Antrodia mushroom β-glucan preparation at dose levels of 0, 500, 1000 and 2000 mg/kg body weight (bw)/day for 90 days...
December 26, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29285586/intracranial-ewing-sarcoma-four-pediatric-examples
#19
Michael J Yang, Ros Whelan, Jennifer Madden, Jean M Mulcahy Levy, B K Kleinschmidt-DeMasters, Todd C Hankinson, Nicholas K Foreman, Michael H Handler
BACKGROUND: Ewing sarcoma typically arises in bone and is unrelated to intraparenchymal small blue cell embryonal central nervous system (CNS) tumors previously designated primitive neuroectodermal tumors (PNETs). When the CNS is impacted, it is usually secondary to local extension from either the epidural space, skull, or intracranial or spinal metastases. Primary examples within the cranial vault are rare, usually dural-based, and are largely case reports in the literature. We detail four pediatric patients with solitary, primary intracranial Ewing sarcoma, all manifesting the archetypal EWRS1 gene rearrangement that confirms diagnosis...
December 28, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29283337/oncocytic-adreno-cortical-tumors-pathological-features-of-16-cases-and-review-of-the-literature
#20
Yesim Ertan, Asuman Argon, Murat Özdemir, Banu Pınar Sarer Yürekli, Zafer Dökümcü, Özer Makay
Oncocytic neoplasms of the adrenal gland are extremely rare tumors. These tumors differ from their nononcocytic counterparts in some respects. The aim of this study was to review and discuss the clinical, histological, and immunohistochemical features of as well as the prognosis for these rare tumors. In total, 16 cases diagnosed as adrenocortical oncocytic neoplasms between January 2011 and December 2016 were included in the study. The demographic data, gross characteristics, histological data, and immunohistochemical data (Chromogranin-A, Synaptophysin, α-Inhibin, Melan-A, Ki67, PHH3) were reevaluated...
2017: Journal of Environmental Pathology, Toxicology and Oncology
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