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https://www.readbyqxmd.com/read/29687078/firing-of-putative-dopamine-neurons-in-ventral-tegmental-area-is-modulated-by-probability-of-success-during-performance-of-a-stop-change-task
#1
Stephen S Tennyson, Adam T Brockett, Nicholas W Hricz, Daniel W Bryden, Matthew R Roesch
Response inhibition, the ability to refrain from unwanted actions, is an essential component of complex behavior and is often impaired across numerous neuropsychiatric disorders such as addiction, attention-deficit hyperactivity disorder (ADHD), schizophrenia, and obsessive-compulsive disorder. Accordingly, much research has been devoted to characterizing brain regions responsible for the regulation of response inhibition. The stop-signal task, a task in which animals are required to inhibit a prepotent response in the presence of a STOP cue, is one of the most well-studied tasks of response inhibition...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29652524/smoking-adhd-and-problematic-video-game-use-a-structural-modeling-approach
#2
Hyo Jin Lee, Denise D Tran, Holly E R Morrell
Problematic video game use (PVGU), or addiction-like use of video games, is associated with physical and mental health problems and problems in social and occupational functioning. Possible correlates of PVGU include frequency of play, cigarette smoking, and attention deficit hyperactivity disorder (ADHD). The aim of the current study was to explore simultaneously the relationships among these variables as well as test whether two separate measures of PVGU measure the same construct, using a structural modeling approach...
April 13, 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29652105/associations-between-problematic-internet-use-and-psychiatric-symptoms-among-university-students-in-japan
#3
Momoko Kitazawa, Michitaka Yoshimura, Mayu Murata, Yuka Sato-Fujimoto, Hidefumi Hitokoto, Masaru Mimura, Kazuo Tsubota, Taishiro Kishimoto
AIM: Research on the adverse effects of internet use has gained importance recently. However, there is currently insufficient data on Japanese young adults' internet use, so we conducted a survey targeting Japanese university students to research Problematic Internet Use (PIU). We also investigated the relationship between PIU and multiple psychiatric symptoms. METHODS: A paper-based survey was conducted at five universities in Japan. Respondents were asked to fill out self-report scales regarding their internet dependency using the Internet Addiction Test (IAT)...
April 13, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29617061/the-relationship-of-internet-addiction-with-attention-deficit-hyperactivity-disorder-effects-of-anxiety-depression-and-self-esteem
#4
Özlem Kahraman, Esra Özdemir Demirci
AIM: Attention Deficit and Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood. Behavioral disinhibition, poor neurocognitive skills and immediate reward preference in childrenwith ADHD have been suggested as risk factors for internet addiction. In our study, we aimed to determine relationship between internet addiction with depression, anxiety, self-esteem in adolescents with ADHD and the features of internet use that predicts internet addiction...
April 4, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29614059/association-between-internet-gaming-disorder-or-pathological-video-game-use-and-comorbid-psychopathology-a-comprehensive-review
#5
REVIEW
Vega González-Bueso, Juan José Santamaría, Daniel Fernández, Laura Merino, Elena Montero, Joan Ribas
The addictive use of video games is recognized as a problem with clinical relevance and is included in international diagnostic manuals and classifications of diseases. The association between "Internet addiction" and mental health has been well documented across a range of investigations. However, a major drawback of these studies is that no controls have been placed on the type of Internet use investigated. The aim of this study is to review systematically the current literature in order to explore the association between Internet Gaming Disorder (IGD) and psychopathology...
April 3, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29593204/modafinil-dependence-a-case-with-attention-deficit-hyperactivity-disorder
#6
Huseyin Alacam, Omer Basay, Selim Tumkaya, Mehmet Mart, Gokce Kar
Modafinil is generally known as a drug with low addiction potential. There are few case reports in the literature demonstrating that Modafinil, stated being capable of diminishing symptoms of attention deficit/hyperactivity disorder (ADHD), causes addiction. In the present article a Modafinil addicted ADHD case, consuming usurious doses (5,000 mg/per day) of Modafinil is presented. The case presented to our psychiatry outpatient clinic due to: requirement of in taking high dose Modafinil in order to achieve the initial effects, difficulty in obtaining the drug, irritability, anxiousness, sleep irregularities, fatigue and unpleasant vivid dreams when he did not use the drug...
March 30, 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/29580130/repeated-intermittent-oral-amphetamine-administration-results-in-locomotor-tolerance-not-sensitization
#7
Amy C Turner, Agata Stramek, Igor Kraev, Michael G Stewart, Paul G Overton, Eleanor J Dommett
BACKGROUND: The phenomenon of locomotor sensitization to injected amphetamine is well-characterised. The increased locomotor activity found acutely is enhanced with repeated intermittent treatment. This effect arises due to hypersensitization of the dopaminergic system and is linked to drug addiction. A clinical population exposed to chronic repeated intermittent amphetamine treatment, such as is found for attention deficit hyperactivity disorder (ADHD), may be expected to be more at risk of addiction following this treatment...
March 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29573063/pattern-of-video-game-use-in-children-with-adhd-and-typical-development
#8
Tanyawan Kietglaiwansiri, Weerasak Chonchaiya
BACKGROUND: Video game playing is a favorite leisure activity amongst children worldwide. Individuals with attention-deficit/hyperactivity disorder (ADHD) often lack of self-control which make them at risk for substance abuse and game addiction. However, there have been conflicting results between studies on the pattern of video gaming and game addiction between those with ADHD and healthy controls. We therefore compared the pattern of video game use and game addiction in Thai children with ADHD with healthy controls...
March 23, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29569336/nonmedical-prescription-stimulant-users-experience-subjective-but-not-objective-impairments-in-attention-and-impulsivity
#9
Alison Looby, Sarah Sant'Ana
BACKGROUND AND OBJECTIVES: Nonmedical prescription stimulant use is frequently reported by college students to improve academic performance, yet it is unknown whether users truly experience cognitive impairments that may drive use. This research compared students with at least one report of nonmedical prescription stimulant use and nonusers on both self-report and objective measures of inattention and impulsivity. METHODS: Two studies examined inattention (N = 155) and impulsivity (N = 115) among college students...
March 23, 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29499467/adverse-physiological-and-psychological-effects-of-screen-time-on-children-and-adolescents-literature-review-and-case-study
#10
Gadi Lissak
A growing body of literature is associating excessive and addictive use of digital media with physical, psychological, social and neurological adverse consequences. Research is focusing more on mobile devices use, and studies suggest that duration, content, after-dark-use, media type and the number of devices are key components determining screen time effects. Physical health effects: excessive screen time is associated with poor sleep and risk factors for cardiovascular diseases such as high blood pressure, obesity, low HDL cholesterol, poor stress regulation (high sympathetic arousal and cortisol dysregulation), and Insulin Resistance...
February 27, 2018: Environmental Research
https://www.readbyqxmd.com/read/29459201/problematic-internet-use-as-an-age-related-multifaceted-problem-evidence-from-a-two-site-survey
#11
Konstantinos Ioannidis, Matthias S Treder, Samuel R Chamberlain, Franz Kiraly, Sarah A Redden, Dan J Stein, Christine Lochner, Jon E Grant
BACKGROUND AND AIMS: Problematic internet use (PIU; otherwise known as Internet Addiction) is a growing problem in modern societies. There is scarce knowledge of the demographic variables and specific internet activities associated with PIU and a limited understanding of how PIU should be conceptualized. Our aim was to identify specific internet activities associated with PIU and explore the moderating role of age and gender in those associations. METHODS: We recruited 1749 participants aged 18 and above via media advertisements in an Internet-based survey at two sites, one in the US, and one in South Africa; we utilized Lasso regression for the analysis...
February 12, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29444606/the-links-between-healthy-problematic-and-addicted-internet-use-regarding-comorbidities-and-self-concept-related-characteristics
#12
Tagrid Leménager, Sabine Hoffmann, Julia Dieter, Iris Reinhard, Karl Mann, Falk Kiefer
Background Addicted Internet users present with higher rates of comorbidities, e.g., attention-deficit hyperactivity disorder (ADHD), depressive, and anxiety disorders. In addition, deficits in self-concept-related characteristics were found in addicted Internet gamers and social network users. The aim of this study was to examine the links between healthy, problematic, and addicted Internet use regarding comorbidities and self-concept-related characteristics. The association between recently developed ADHD-like symptoms without an underlying diagnosis and addictive Internet use was also examined...
February 15, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29397534/chronic-methylphenidate-alters-tonic-and-phasic-glutamate-signaling-in-the-frontal-cortex-of-a-freely-moving-rat-model-of-adhd
#13
Erin M Miller, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, Paul E A Glaser
Glutamate dysfunction has been implicated in a number of substance of abuse studies, including cocaine and methamphetamine. Moreover, in attention-deficit/hyperactivity disorder (ADHD), it has been discovered that when the initiation of stimulant treatment occurs during adolescence, there is an increased risk of developing a substance use disorder later in life. The spontaneously hypertensive rat (SHR) serves as a phenotype for ADHD and studies have found increased cocaine self-administration in adult SHRs when treated with the stimulant methylphenidate (MPH) during adolescence...
February 3, 2018: Neurochemical Research
https://www.readbyqxmd.com/read/29391802/adhd-and-lifestyle-habits-in-czech-adults-a-national-sample
#14
Simon Weissenberger, Radek Ptacek, Martina Vnukova, Jiri Raboch, Martina Klicperova-Baker, Lucie Domkarova, Michal Goetz
Background: Adult attention-deficit/hyperactivity disorder (ADHD) has been added as a diagnosis to the Diagnostic and Statistical Manual of Mental Disorders version 5 (DSM5) in 2013, thus making ADHD, which has been classically known as a childhood disorder, a life-long disorder. Those suffering from the condition show very specific behavioral traits, which manifest as lifestyle habits; they also show comorbidities that can be the symptoms and/or consequences of certain lifestyles. Materials and methods: The targeted population was adults aged 18-65 years...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29343228/problematic-internet-use-and-psychiatric-co-morbidity-in-a-population-of-japanese-adult-psychiatric-patients
#15
Hille T de Vries, Takashi Nakamae, Kenji Fukui, Damiaan Denys, Jin Narumoto
BACKGROUND: Many studies reported the high prevalence of problematic internet use (PIU) among adolescents (13-50%), and PIU was associated with various psychiatric symptoms. In contrast, only a few studies investigated the prevalence among the adult population (6%). This study aimed to investigate the prevalence of PIU and psychiatric co-morbidity among adult psychiatric patients. METHODS: Three hundred thirty-three adult psychiatric patients were recruited over a 3-month period...
January 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29321705/attention-deficit-hyperactivity-disorder-and-nicotine-dependence-in-adults
#16
Bülent Bilgi, Umut Mert Aksoy, Özge Şahmelikoğlu Onur, Ayşe Fulya Maner
Introduction: The aim of this study is to assess clinical characteristics and smoking profiles of individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) and compare their nicotine dependence status with healthy controls for better understanding the mutual and complex relationship between ADHD and smoking. Methods: We included the following participants in the study: 40 adults with the diagnosis of ADHD, 40 participants who visited the smoking cessation polyclinic without any psychiatric disorders, and 40 healthy controls...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29316800/pro-dopamine-regulator-kb220z-attenuates-hoarding-and-shopping-behavior-in-a-female-diagnosed-with-sud-and-adhd
#17
Thomas McLaughlin, Kenneth Blum, Bruce Steinberg, Edward J Modestino, Lyle Fried, David Baron, David Siwicki, Eric R Braverman, Rajendra D Badgaiyan
Background Addictive-like behaviors (e.g., hoarding and shopping) may be the result of the cumulative effects of dopaminergic and other neurotransmitter genetic variants as well as elevated stress levels. We, therefore, propose that dopamine homeostasis may be the preferred goal in combating such challenging and unwanted behaviors, when simple dopaminergic activation through potent agonists may not provide any resolution. Case presentation C.J. is a 38-year-old, single, female, living with her mother. She has a history of substance use disorder as well as attention deficit hyperactivity disorder, inattentive type...
March 1, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29305714/diagnoses-of-cardiovascular-disease-or-substance-addiction-abuse-in-us-adults-treated-for-adhd-with-stimulants-or-atomoxetine-is-use-consistent-with-product-labeling
#18
Kathleen A Fairman, Lindsay E Davis, Alyssa M Peckham, David A Sclar
BACKGROUND: Among US adults, utilization of pharmacotherapy for attention-deficit hyperactivity disorder (ADHD) has increased more than ninefold since 1995-1996. Potential contraindications to ADHD pharmacotherapy include serious cardiovascular disease (CVD) and, for stimulants, addictions and bipolar disorder (BPD). OBJECTIVE: To assess the prevalence of potential contraindications among adults treated with ADHD pharmacotherapy. METHODS: A retrospective cohort analysis was performed using the Truven Health MarketScan® database...
March 2018: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29280392/comorbidity-of-internet-use-disorder-and-attention-deficit-hyperactivity-disorder-two-adult-case-control-studies
#19
Martin Bielefeld, Marion Drews, Inken Putzig, Laura Bottel, Toni Steinbüchel, Jan Dieris-Hirche, Gregor R Szycik, Astrid Müller, Mandy Roy, Martin Ohlmeier, Bert Theodor Te Wildt
Objectives There is good scientific evidence that attention deficit hyperactivity disorder (ADHD) is both a predictor and a comorbidity of addictive disorders in adulthood. These associations not only focus on substance-related addictions but also on behavioral addictions like gambling disorder and Internet use disorder (IUD). For IUD, systematic reviews have identified ADHD as one of the most prevalent comorbidities besides depressive and anxiety disorders. Yet, there is a need to further understand the connections between both disorders to derive implications for specific treatment and prevention...
December 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29169199/-internet-addiction-suicidality-and-non-suicidal-self-harming-behavior-a-systematic-review
#20
Toni Andreas Steinbüchel, Stephan Herpertz, Ina Külpmann, Aram Kehyayan, Jan Dieris-Hirche, Bert Theodor Te Wildt
Background Internet addiction (IA) is associated with a high rate of co-morbid mental disorders, especially depression, anxiety disorders, ADHD and personality disorders and a considerable level of psychological strain. In terms of risk assessment, the present work investigates the current research literature on suicidal behavior and non-suicidal self-injurious behavior (NSSI). Methods We performed a systematic literature search in 14 databases on title and abstract level for the most common keywords for IA, NSSI and suicidality...
November 23, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
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