Jose A Joglar, Elaine Y Wan, Mina K Chung, Alejandra Gutierrez, Mark S Slaughter, Brian P Bateson, Michael Loguidice, Mark Drazner, Peter M Kistler, Basil Saour, Jeanne E Poole, Ghulam Murtaza, Mohit K Turagam, Justin Vader, Dhanunjaya Lakkireddy, Edo Y Birati, Ravi Dhingra, Rakesh Gopinathannair
Orthotropic heart transplantation remains the most effective therapy for patients with end-stage heart failure, with a median survival of ≈13 years. Yet, a number of complications are observed after orthotropic heart transplantation, including atrial and ventricular arrhythmias. Several factors contribute to arrhythmias, such as autonomic denervation, effect of the surgical technique, acute and chronic rejection, and transplant vasculopathy among others. To minimize risk of future arrhythmias, the bicaval technique and minimizing ischemic time are current surgical standards...
March 2021: Circulation. Arrhythmia and Electrophysiology