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https://www.readbyqxmd.com/read/29792554/effect-of-acetazolamide-and-methazolamide-on-diaphragm-and-dorsiflexor-fatigue-a-randomized-controlled-trial
#1
Paolo B Dominelli, Chris J McNeil, Tyler Dennis Vermeulen, Troy J R Stuckless, Courtney V Brown, Giulio S Dominelli, Erik Richard Swenson, Lucas J Teppema, Glen Edward Foster
Acetazolamide, a carbonic anhydrase (CA) inhibitor used clinically and to prevent acute mountain sickness, worsens skeletal muscle fatigue in animals and humans. In animals, methazolamide, a methylated analogue of acetazolamide and an equally potent CA inhibitor, reportedly exacerbates fatigue less than acetazolamide. Accordingly, we sought to determine, in humans, if methazolamide would attenuate diaphragm and dorsiflexor fatigue compared to acetazolamide. Healthy men (dorsiflexor: n=12; diaphragm: n=7) performed fatiguing exercise on three occasions, after ingesting acetazolamide (250 mg three times a day) and then in random order, methazolamide (100 mg twice a day) or placebo for 48 h...
May 24, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29791703/biological-intercalary-reconstruction-with-bone-grafts-after-joint-sparing-resection-of-the-lower-limb-is-this-an-effective-and-durable-solution-for-joint-preservation
#2
Francesco Muratori, Francesca Totti, Antonio D'Arienzo, Maurizio Scorianz, Guido Scoccianti, Giovanni Beltrami, Francesco Rosario Campo, Carmine Citarelli, Rodolfo Capanna, Domenico Andrea Campanacci
Due to advances in neoadjuvant therapies and preoperative imaging modalities, joint-sparing resections have become appealing in bone tumor surgery. However, the intercalary reconstruction of metadiaphyseal bone defects of the femur and the tibia after juxta-articular tumor resection remains challenging. Both biological and prosthetic reconstructions have been used for joint-sparing resections, but little is known about the long-term outcome of these procedures. The authors reviewed a consecutive series of 64 patients treated with joint-sparing intercalary resection and reconstruction with bone grafts...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29781914/corr-insights%C3%A2-closed-reduction-osteotomy-and-fibular-graft-are-effective-in-treating-pediatric-femoral-neck-pseudarthrosis-after-infection
#3
Lewis E Zionts
No abstract text is available yet for this article.
May 17, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29773868/coexistence-of-nerve-enlargement-and-neuratrophy-detected-by-ultrasonography-in-leprosy-patients
#4
Xiaohua Chen, Liangfu Zhang, Meiying Huang, Xiuli Zhai, Yan Wen, Chunzhi Pan
The purpose of this study was to evaluate peripheral neural impairment in leprosy patients by ultrasonography (US). The cross-sectional areas (CSAs) of the median (M), ulnar (U) and common fibular (CF) nerves were compared in 71 leprosy patients and 29 healthy controls, and the data were analyzed between the leprosy, multibacillary (MB)/paucibacillary (PB), reaction (R)/no reaction (NR), disability (D)/no disability (ND), and longer/shorter duration groups after treatment. We found that for the nerves located in upper limbs, the CSAs were significantly increased in the leprosy patients vs the controls; the PB group vs the MB group; the R group vs the NR group; the ND group vs the D group; and the longer duration group vs the shorter duration group at some positions of the M nerve and U nerve...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29770342/fibular-collateral-ligament-varus-stress-radiographic-analysis-using-3-different-clinical-techniques
#5
Patrick W Kane, Mark E Cinque, Gilbert Moatshe, Jorge Chahla, Nicholas N DePhillipo, Matthew T Provencher, Robert F LaPrade
Background: Fibular collateral ligament (FCL) tears are challenging to diagnose. Left untreated, FCL tears lead to residual ligament instability and increased joint loading on the medial compartment of the knee. Additionally, when a concomitant anterior cruciate ligament (ACL) reconstruction is performed, increased forces on reconstruction grafts occur, which may lead to premature graft failure. Stress radiographs constitute a reliable and validated technique for the objective assessment of a complete grade III FCL tear...
May 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29756392/successful-treatment-of-severe-facial-lymphedema-by-lymphovenous-anastomosis
#6
Yusuke Inatomi, Sei Yoshida, Kenichi Kamizono, Masuo Hanada, Ryuji Yasumatsu, Hideki Kadota
BACKGROUND: Facial edema is a common complication after neck dissection and/or chemoradiotherapy for head and neck cancer. Edema subsides spontaneously in most cases but sometimes persists, in which case surgical intervention is required. We report a case of severe facial edema that showed significant improvement upon lymphovenous anastomosis (LVA). METHODS: A 66-year-old man with oral floor cancer developed progressive facial lymphedema after tumor resection, bilateral neck dissections, chemoradiotherapy, and fibular and rectus abdominis musculocutaneous flap transfer...
May 13, 2018: Head & Neck
https://www.readbyqxmd.com/read/29755607/risk-factors-for-the-development-of-nerve-palsy-following-primary-total-hip-arthroplasty
#7
Shunsuke Kawano, Motoki Sonohata, Masaru Kitajima, Masaaki Mawatari
Background: Nerve palsy following total hip arthroplasty (THA) is a complication that worsens the functional prognosis. The present study analyzed the risk factors of nerve palsy following THA. Methods: The subjects of this study included 6,123 cases in which primary THA was performed under spinal anesthesia with cementless implants used in the posterolateral approach. Results: Fourteen cases (0.22%) developed nerve palsy following THA, all of which involved palsy of the entire peroneal nerve region...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29744100/bilateral-fibular-hemimelia-associated-with-hip-dislocation-and-femoral-head-necrosis
#8
Salahiddine Saghir, Hicham Bousbaa, Aomar Agadr
We describe a case of association of congenital bone abnormalities. It will allow clinicians to look systematically for other skeletal malformations and teach them how to evaluate these cases for the first time. This early screening will enable appropriate treatment to avoid complications and to preserve functional prognosis.
May 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29738854/age-related-changes-in-female-mouse-cortical-bone-microporosity
#9
Haniyeh Hemmatian, Michaël R Laurent, Astrid D Bakker, Dirk Vanderschueren, Jenneke Klein-Nulend, G Harry van Lenthe
Osteocyte lacunae are small cavities within the bone matrix. Their dimensions and spatial arrangement affect bone mechanical properties. Furthermore, their size and shape affect the strain in bone tissue close to the lacunae; hence, they are supposed to affect the mechanosensory function of the osteocytes residing in the lacunae. It was the purpose of this study to quantify the morphological features of osteocyte lacunae, whether these are affected by aging and whether these vary among different anatomical location...
May 5, 2018: Bone
https://www.readbyqxmd.com/read/29736923/reconstruction-of-complex-tissue-defect-of-forearm-with-a-chimeric-flap-composed-of-a-sural-neurocutaneous-flap-and-a-vascularized-fibular-graft-a-case-report
#10
Chunyang Wang, Jia Xu, Gen Wen, Yimin Chai
One-stage reconstruction of composite bone and soft-tissue defects in the forearm remains a tough challenge. Here, we present a case of reconstruction of complex tissue defect at forearm with a chimeric flap consisting of a sural neurocutaneous flap and a fibular graft. A 61-year-old man suffered from a machine crush injury in his left forearm, resulting in a complex tissue defect including extensive dorsomedial soft-tissue, digit extensor muscles of 2-4 fingers, the muscle flexor carpi ulnaris, the ulna bone with 5...
May 7, 2018: Microsurgery
https://www.readbyqxmd.com/read/29735375/which-additional-augmented-fixation-procedure-decreases-surgical-failure-after-proximal-humeral-fracture-with-medial-comminution-fibular-allograft-or-inferomedial-screws
#11
Doo-Sup Kim, Doo-Hyung Lee, Yong-Min Chun, Sang-Jin Shin
BACKGROUND: The purpose of this study was to compare clinical and radiologic results between treatment with locking plate fixation and fibular allograft augmentation (FA) and treatment with locking plate fixation and additional inferomedial screws (IMSs) in 3- or 4-part proximal humeral fractures with medial comminution in geriatric patients. METHODS: We enrolled 164 patients with 3- or 4-part proximal humeral fractures with medial comminution who were treated with locking plates...
May 4, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29735332/-the-fascio-cutaneous-fibular-island-flap
#12
A-C Masquelet, J Gaillard, A Cambon-Binder, R Mauprivez
The perforators of the fibular artery provide a well vascularised supra fascial network which allows to raise a proximally or a distally based island fascio cutaneous flap with an adipo-fascial pedicle. We present a short series of five cases of this flap for coverage of soft tissue defects involving the region of the knee, the distal third of the leg and the lateral aspect of the heel. All flaps healed entirely without venous congestion. The advantages of the fascio cutaneous fibular island flap are the supine operative position, the preservation of the sural nerve and the lesser saphenous vein and a pivot point which can be located at the middle third of the leg...
May 4, 2018: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29734909/the-observation-of-the-vein-distribution-of-a-partial-toe-transfer-flaps-with-a-short-vascular-pedicle
#13
Koichi Kobayashi, Katsuyasu Fukasawa, Naoko Masuyama
BACKGROUND: When performing partial toe-transfer flaps with a short vascular pedicle, as the flap becomes smaller, the likelihood of securing veins in the flap decreases. The purpose of this study was to clarify how frequently the partial toe-transfer flap with a short pedicle (free vascularized half-big toenail flap) contains veins and elucidate how frequently we can secure the veins with an artery via the first web space approach alone, using the Genial Viewer (a near-infrared light transmission imaging device)...
June 2018: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29732952/clinical-comparison-of-scapular-fibular-and-iliac-crest-osseal-free-flaps-in-maxillofacial-reconstructions
#14
T Wilkman, A Husso, P Lassus
BACKGROUND AND AIMS: This study compared the three most used composite flaps in maxillofacial reconstructions in our institute. PATIENTS AND METHODS: Between 2000 and 2012, a total of 163 patients with mandibular, maxillary, and orbital defects received either scapular, fibular, or iliac crest osseal reconstructions in Helsinki University Hospital, Departments of Plastic Surgery and Maxillofacial Surgery. Data regarding the patient demographics, complications, and outcomes were analyzed...
May 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29730061/computed-tomographic-angiographic-perforator-localization-for-virtual-surgical-planning-of-osteocutaneous-fibular-free-flaps-in-head-and-neck-reconstruction
#15
Kyle S Ettinger, Amy E Alexander, Kevin Arce
Virtual surgical planning (VSP), computer-aided design and computer-aided modeling, and 3-dimensional printing are 3 distinct technologies that have become increasingly used in head and neck oncology and microvascular reconstruction. Although each of these technologies has long been used for treatment planning in other surgical disciplines, such as craniofacial surgery, trauma surgery, temporomandibular joint surgery, and orthognathic surgery, its widespread use in head and neck reconstructive surgery remains a much more recent event...
April 10, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29708573/medial-compartment-decompression-by-proximal-fibular-osteotomy-a-biomechanical-cadaver-study
#16
Todd Baldini, Jesse Roberts, Jiandong Hao, Kenneth Hunt, Michael Dayton, Craig Hogan
Medial compartment knee osteoarthritis is a painful and debilitating disease. A proximal fibular osteotomy is a novel, simple surgical technique that may reduce pain and improve function for patients with osteoarthritis. The purpose of this biomechanical cadaver study was to determine what effect proximal fibular osteotomy had on knee joint and ankle pressures and tibia strain. Ten matched pairs of cadaver legs were tested in compression to 1.1 times body weight comparing intact and with proximal fibular osteotomy at 0°, 15°, and 30° of flexion...
April 27, 2018: Orthopedics
https://www.readbyqxmd.com/read/29705234/syndesmosis-fixation-in-unstable-ankle-fractures-using-a-partially-threaded-5-0-mm-cannulated-screw
#17
Seung Yeol Lee, Sang Young Moon, Moon Seok Park, Byung Chae Jo, Hyunseok Jeong, Kyoung Min Lee
The present study evaluated the radiographic outcomes of syndesmosis injuries treated with a partially threaded 5.0-mm cannulated screw. The present study included 58 consecutive patients with syndesmosis injuries concurrent with ankle fractures who had undergone operative fixation with a partially threaded 5.0-mm cannulated screw to repair the syndesmosis injury. Radiographic indexes, including the medial clear space, tibiofibular overlap, tibiofibular clear space, and fibular position on the lateral radiograph, were measured on the preoperative, immediate postoperative, and final follow-up radiographs...
April 25, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29703261/biomechanical-analysis-of-plate-systems-for-proximal-humerus-fractures-a-systematic-literature-review
#18
REVIEW
Ali Jabran, Chris Peach, Lei Ren
BACKGROUND: Proximal humerus fractures are the third most common in the human body but their management remains controversial. Open reduction and internal fixation with plates is one of the leading modes of operative treatment for these fractures. The development of technologies and techniques for these plates, during the recent decades, promise a bright future for their clinical use. A comprehensive review of in vitro biomechanical studies is needed for the comparison of plates' mechanical performance and the testing methodologies...
April 27, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29702024/video-preoperative-ct-angiography-for-fibular-free-flap-reconstructions
#19
Bilal Mujtaba, Gaurav K Synghal, Patrick B Garvey, Behrang Amini, Tamara Miner Haygood, John E Madewell, Colleen M Costelloe
OBJECTIVE: The objective of this video article is to provide an introduction to the use of fibular free flaps. Normal and variant vascular anatomy of the fibular free flap is discussed, as are imaging acquisition and CT angiography interpretation, computer-assisted design and manufacturing, and the limitations of the fibular free flap. CONCLUSION: The fibular free flap is commonly used for head and neck reconstructive surgery. Variation exists between individuals regarding the origin of the peroneal artery and the perforating arteries...
April 27, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29700593/neurovascular-and-tendon-injuries-due-to-ankle-arthroscopy-portals-a-meta-analysis-of-interventional-cadaveric-studies
#20
Kaissar Yammine, Chahine Assi
Neurovascular and tendon structures are considered at risk when performing ankle arthroscopy. Injury rate and distance from portals to such structures varied in the literature. The aim of this meta-analysis is to evaluate the injury risk of these structures in terms of proximity and injury prevalence. Thirteen studies including 184 cadaveric ankle arthroscopy procedures met the inclusion criteria. The antero-central portal exhibited the highest frequencies of nerve/vessel proximity and nerve/vessel missed injuries...
April 26, 2018: Surgical and Radiologic Anatomy: SRA
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