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https://www.readbyqxmd.com/read/28687481/prevalence-and-risk-factors-for-hiv-hepatitis-b-and-hepatitis-c-in-people-with-severe-mental-illness-a-total-population-study-of-sweden
#1
Clarissa Bauer-Staeb, Lena Jörgensen, Glyn Lewis, Christina Dalman, David P J Osborn, Joseph F Hayes
BACKGROUND: Severe mental illness is associated with increased morbidity and mortality. The elevated risk of blood-borne viruses (BBVs) in people with severe mental illness is of concern, but the full extent of this problem is unclear. We aimed to determine the prevalence of and risk factors for BBVs in people with severe mental illness. METHODS: In this nationwide, population-based, cross-sectional study, we estimated the point prevalence of HIV, hepatitis B (HBV), and hepatitis C (HCV) in people with severe mental illness, including the total adult (≥18 years) Swedish population...
July 4, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28682528/s-adenosylmethionine-same-for-neuropsychiatric-disorders-a-clinician-oriented-review-of-research
#2
REVIEW
Anup Sharma, Patricia Gerbarg, Teodoro Bottiglieri, Lila Massoumi, Linda L Carpenter, Helen Lavretsky, Philip R Muskin, Richard P Brown, David Mischoulon
OBJECTIVE: A systematic review on S-adenosylmethionine (SAMe) for treatment of neuropsychiatric conditions and comorbid medical conditions. DATA SOURCES: Searches were conducted in PubMed, EMBASE, PsycINFO, Cochrane Library, CINAHL, and Google Scholar databases between July 15, 2015, and September 28, 2016, by combining search terms for SAMe (s-adenosyl methionine or s-adenosyl-l-methionine) with terms for relevant disease states (major depressive disorder, MDD, depression, perinatal depression, human immunodeficiency virus, HIV, Parkinson's, Alzheimer's, dementia, anxiety, schizophrenia, psychotic, 22q11...
June 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28617372/-characteristics-of-psychopathological-symptomatology-in-hiv-infection-schizophrenic-patients
#3
D A Polyanskiy, V V Kalinin
AIM: To study the psychopathological structure of psychotic syndromes in HIV-infected schizophrenic patients and in patients without HIV infection. MATERIAL AND METHODS: Forty HIV-infected patients, 23 women and 17 men, with confirmed diagnosis of schizophrenia were included in the study. The control group consisted of 40 patients without HIV infection, 23 women (48%) and 17 men (52%). The psychopathological state in all patients was assessed with the PANSS. Flow cytometry was used to measure immunological parameters in HIV-infected patients...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28449629/the-changing-epidemiology-of-hiv-in-the-criminal-justice-system
#4
Jacques Baillargeon, John S Pulvino, Jane E Leonardson, Lannette C Linthicum, Brie Williams, Joseph Penn, Robert S Williams, Gwen Baillargeon, Owen J Murray
Although the rate of HIV infection among US prison inmates is considerably higher than that of the general population, little is known about age-related changes in HIV-infected inmates over the last decade. This study of the nation's largest state prison system examined (1) whether the mean age of the HIV-infected inmate increased over the last decade, and (2) whether the prevalence of HIV and associated comorbidities varied according to age. The study population included all 230,103 inmates incarcerated in the Texas prison system for any duration during 2014...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28326328/cooccurrences-of-putative-endogenous-retrovirus-associated-diseases
#5
REVIEW
Christine Brütting, Alexander Emmer, Malte E Kornhuber, Martin S Staege
At least 8% of the human genome is composed of endogenous retrovirus (ERV) sequences. ERVs play a role in placental morphogenesis and can sometimes protect the host against exogenous viruses. On the other hand, ERV reactivation has been found to be associated with different diseases, for example, multiple sclerosis (MS), schizophrenia, type 1 diabetes mellitus (T1D), or amyotrophic lateral sclerosis (ALS). Little is known about the cooccurrence of these diseases. If all these diseases are caused by ERV, antiretroviral therapy should perhaps also show some effects in the other diseases...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28246140/evaluating-process-and-clinical-outcomes-of-a-primary-care-mental-health-integration-project-in-rural-rwanda-a-prospective-mixed-methods-protocol
#6
Stephanie L Smith, Claire Nancy Misago, Robyn A Osrow, Molly F Franke, Jean Damascene Iyamuremye, Jeanne D'Arc Dusabeyezu, Achour A Mohand, Manzi Anatole, Yvonne Kayiteshonga, Giuseppe J Raviola
INTRODUCTION: Integrating mental healthcare into primary care can reduce the global burden of mental disorders. Yet data on the effective implementation of real-world task-shared mental health programmes are limited. In 2012, the Rwandan Ministry of Health and the international healthcare organisation Partners in Health collaboratively adapted the Mentoring and Enhanced Supervision at Health Centers (MESH) programme, a successful programme of supported supervision based on task-sharing for HIV/AIDS care, to include care of neuropsychiatric disorders within primary care settings (MESH Mental Health)...
February 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28215710/altered-mental-status-in-the-emergency-department-can-an-electrocardiogram-show-the-right-way-to-go
#7
Andre Dias, Emiliana Franco, Jasmine Martinez, Vincent M Figueredo
A 38-year-old African American male patient with a past medical history of human immunodeficiency virus and schizophrenia who was noncompliant with medications presented to the emergency department (ED) after activation of the local crisis response center for altered mental status. Upon arrival he was lethargic and uncooperative, unable to provide any significant details apart from pleuritic chest pain. His blood pressure was 133/88 mmHg, heart rate 43 beats per minute and initial body temperature 36.1 °C which prompted an electrocardiogram (EKG)...
May 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28195778/transitioning-from-medicaid-disability-coverage-to-long-term-medicare-coverage-the-case-of-people-living-with-hiv-aids-in-california
#8
Warren S Comulada, Katherine A Desmond, Jennifer L Gildner, Arleen A Leibowitz
Medicaid can serve as a bridge to Medicare coverage for the long-term disabled with sufficient covered work experience. We perform multinomial logistic regression on 2007-2010 Medicare and Medicaid claims data to examine transitions to Medicare for people living with HIV/AIDS (PLWHA) in California who had Medicaid coverage in 2007. We find only 16% had obtained Medicare coverage by 2010. African-Americans, women, individuals with schizophrenia diagnoses, alcohol or substance abuse disorders, and any physical comorbidity were significantly less likely than others to obtain Medicare (p < 0...
February 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/27872683/safe-and-effective-sofosbuvir-based-therapy-in-patients-with-mental-health-disease-on-hepatitis-c-virus-treatment
#9
Lydia Shuk Yee Tang, Jack Masur, Zayani Sims, Amy Nelson, Anu Osinusi, Anita Kohli, Sarah Kattakuzhy, Michael Polis, Shyam Kottilil
AIM: To study impact of baseline mental health disease on hepatitis C virus (HCV) treatment; and Beck's Depression Inventory (BDI) changes with sofosbuvir- and interferon-based therapy. METHODS: This is a retrospective cohort study of participants from 5 studies enrolled from single center trials conducted at the Clinical Research Center of the National Institutes of Health, Bethesda, MD, United States. All participants were adults with chronic HCV genotype 1 infection and naïve to HCV therapy...
November 8, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27833555/ginkgolic-acid-protects-against-a%C3%AE-induced-synaptic-dysfunction-in-the-hippocampus
#10
Dalila Mango, Filippo Weisz, Robert Nisticò
Ginkgo leaf is the most used form of supplement for cognitive ailments. The standardized extract formulation EGb 761 is a dietary supplement with proven benefit in several neurological and psychiatric conditions including memory decline in Alzheimer's disease, schizophrenia and dementia. Ginkgolic acid (GA) is a component of this extract which shows pleiotropic effects including antitumoral and anti-HIV action; however, its effect on memory is still unknown. Here, we carried out an electrophysiological analysis to investigate the effects of GA on long term potentiation and synaptic transmission at CA1 hippocampal synapses...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27824636/consideration-of-clozapine-and-gender-affirming-medical-care-for-an-hiv-positive-person-with-schizophrenia-and-fluctuating-gender-identity
#11
Adrienne T Gerken, Shunda McGahee, Alex S Keuroghlian, Oliver Freudenreich
No abstract text is available yet for this article.
November 2016: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/27752767/genetic-factor-common-to-schizophrenia-and-hiv-infection-is-associated-with-risky-sexual-behavior-antagonistic-vs-synergistic-pleiotropic-snps-enriched-for-distinctly-different-biological-functions
#12
Qian Wang, Renato Polimanti, Henry R Kranzler, Lindsay A Farrer, Hongyu Zhao, Joel Gelernter
Schizophrenia (SZ) and HIV infection are serious disorders with a complex phenotypic relationship. Observational studies have described their comorbidity; their genetic correlation is not well studied. We performed extensive analysis in search of common genetic factors for SZ and HIV, and their relationship with risky sexual behavior (RSB). Summary statistics from genome-wide association studies of HIV infection and schizophrenia were obtained and 2379 European Americans were genotyped and assessed for RSB score...
January 2017: Human Genetics
https://www.readbyqxmd.com/read/27609030/hiv-prevention-advice-for-people-with-serious-mental-illness
#13
REVIEW
Nicola Wright, Athfah Akhtar, Graeme E Tosh, Andrew V Clifton
BACKGROUND: People with serious mental illness have rates of Human Immuno-deficiency Virus (HIV) infection higher than expected in the general population for the same demographic area. Despite this elevated prevalence, UK national strategies around sexual health and HIV prevention do not state that people with serious mental illness are a high risk group. However, a significant proportion in this group are sexually active and engage in HIV-risk behaviours including having multiple sexual partners, infrequent use of condoms and trading sex for money or drugs...
September 9, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27512062/nf-%C3%AE%C2%BAb-and-irf1-induce-endogenous-retrovirus-k-expression-via-interferon-stimulated-response-elements-in-its-5-long-terminal-repeat
#14
Mamneet Manghera, Jennifer Ferguson-Parry, Rongtuan Lin, Renée N Douville
UNLABELLED: Thousands of endogenous retroviruses (ERV), viral fossils of ancient germ line infections, reside within the human genome. Evidence of ERV activity has been observed widely in both health and disease. While this is most often cited as a bystander effect of cell culture or disease states, it is unclear which signals control ERV transcription. Bioinformatic analysis suggests that the viral promoter of endogenous retrovirus K (ERVK) is responsive to inflammatory transcription factors...
October 15, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27437126/the-effectiveness-of-mobile-phone-text-messaging-in-improving-medication-adherence-for-patients-with-chronic-diseases-a-systematic-review
#15
REVIEW
Roghayeh Ershad Sarabi, Farahnaz Sadoughi, Roohangiz Jamshidi Orak, Kambiz Bahaadinbeigy
CONTEXT: Medication non-adherence is a commonly observed problem in the self-administration of treatment, regardless of the disease type. Text messaging reminders, as electronic reminders, provide an opportunity to improve medication adherence. In this study, we aimed to provide evidence addressing the question of whether text message reminders were effective in improving patients' adherence to medication. EVIDENCE ACQUISITION: We carried out a systematic literature search, using the five electronic bibliographic databases: PubMed, Embase, PsycINFO, CINAHL, and the Cochrane central register of controlled trials...
May 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27306965/do-they-see-dead-people-cultural-factors-and-sensitivity-in-screening-for-schizophrenia-spectrum-disorders
#16
MacKenzie R Peltier, Seandra J Cosgrove, Kelechi Ohayagha, Kathleen A Crapanzano, Glenn N Jones
OBJECTIVE: Schizophrenia spectrum disorders (SSDs), are diagnosed more frequently among African-Americans (AAs) than Caucasians. It has been suggested that cultural differences in symptom presentation and endorsement (including reporting spiritual/religious experiences) may influence this disparity. The current study investigated the relationship between endorsement of spiritual auditory and visual hallucinations and subsequent diagnosis of SSD among AA patients. DESIGN: Participants (N = 471 AAs) completed the Mini International Neuropsychiatric Interview-Plus (MINI-Plus) Screening Interview as part of their intake to a HIV outpatient clinic...
June 16, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27114969/burden-among-caregivers-of-children-living-with-human-immunodeficiency-virus-in-north-india
#17
Ramesh Chand Chauhan, Sanjay Kumar Rai, Shashi Kant, Rakesh Lodha, Nand Kumar, Neelima Singh
BACKGROUND: Due to wider access to and free antiretroviral therapy (ART) program, the number of children dying due to acquired immune deficiency syndrome (AIDS)-related causes has declined and the nature and duration of human immunodeficiency virus (HIV)/AIDS caregiving has also dramatically altered. The care of children living with HIV/AIDS (CLHA) places a significant additional burden on the caregivers. AIMS: This study was conducted to assess the perceived burden among caregivers of children living with HIV in North India...
March 2016: North American Journal of Medical Sciences
https://www.readbyqxmd.com/read/27075223/-treatment-resistant-psychosis-due-to-interaction-between-ritonavir-and-olanzapine-case-report-and-literature-review
#18
REVIEW
Th van Oeffelt, E J D Prinsen
Patients with schizophrenia are eight times more likely than healthy individuals to become infected with the human immunodeficiency virus (hiv). Although in vitro studies provide some data on the interaction between antipsychotics and retroviral agents, there is a lack of in vitro data on this subject. We describe the case of a 35-year-old patient who suffered from schizophrenia, polydrug abuse and an hiv infection and who also had treatment-resistant psychosis. An interaction between the antiretroviral drug ritonavir and the antipsychotic olanzapine turned out to be the cause of the treatment resistance...
2016: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/26916628/strengths-weaknesses-opportunities-and-challenges-for-long-acting-injectable-therapies-insights-for-applications-in-hiv-therapy
#19
REVIEW
Andrew Owen, Steve Rannard
Advances in solid drug nanoparticle technologies have resulted in a number of long-acting (LA) formulations with the potential for once monthly or longer administration. Such formulations offer great utility for chronic diseases, particularly when a lack of medication compliance may be detrimental to treatment response. Two such formulations are in clinical development for HIV but the concept of LA delivery has its origins in indications such as schizophrenia and contraception. Many terms have been utilised to describe the LA approach and standardisation would be beneficial...
August 1, 2016: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/26863335/racial-differences-in-chronic-conditions-and-sociodemographic-characteristics-among-high-utilizing-veterans
#20
Jessica Y Breland, Christine Pal Chee, Donna M Zulman
PURPOSE: African-Americans are disproportionally represented among high-risk, high-utilizing patients. To inform program development for this vulnerable population, the current study describes racial variation in chronic conditions and sociodemographic characteristics among high-utilizing patients in the Veterans Affairs Healthcare System (VA). METHODS: We identified the 5 % most costly Veterans who used inpatient or outpatient care at the VA during fiscal year 2010 (N = 237,691) based on costs of inpatient and outpatient care, pharmacy services, and VA-sponsored contract care...
June 2015: Journal of Racial and Ethnic Health Disparities
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