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https://www.readbyqxmd.com/read/28445478/delayed-histochemical-alterations-within-the-neurovascular-unit-due-to-transient-focal-cerebral-ischemia-and-experimental-treatment-with-neurotrophic-factors
#1
Dominik Michalski, Roman Pitsch, Deepu R Pillai, Bianca Mages, Susanne Aleithe, Jens Grosche, Henrik Martens, Felix Schlachetzki, Wolfgang Härtig
Current stroke therapy is focused on recanalizing strategies, but neuroprotective co-treatments are still lacking. Modern concepts of the ischemia-affected neurovascular unit (NVU) and surrounding penumbra emphasize the complexity during the transition from initial damaging to regenerative processes. While early treatment with neurotrophic factors was shown to result in lesion size reduction and blood-brain barrier (BBB) stabilization, cellular consequences from these treatments are poorly understood. This study explored delayed cellular responses not only to ischemic stroke, but also to an early treatment with neurotrophic factors...
2017: PloS One
https://www.readbyqxmd.com/read/28445219/canadian-national-guidelines-and-recommendations-for-integrating-career-advising-into-medical-school-curricula
#2
Kelly Howse, June Harris, Nancy Dalgarno
Career planning, decision making about specialty choice, and preparation for residency matching are significant sources of stress for medical students. Attempts have been made to structure and formalize career advising by including it in accreditation standards. There is an expressed need for national guidelines on career advising for medical students. The Future of Medical Education in Canada Postgraduate (FMEC PG) Implementation Project was created to ensure Canadian medical trainees receive the best education possible...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28444754/retrospective-study-on-the-occurrence-of-canine-lymphoma-and-associated-breed-risks-in-a-population-of-dogs-in-nsw-2001-2009
#3
Ppy Yau, N K Dhand, P C Thomson, R M Taylor
OBJECTIVE: To identify risk factors for canine lymphoma in dogs from New South Wales, Australia, and to compare factors affecting remission duration. METHODS: Client-owned dogs diagnosed with lymphoma presented to the University Veterinary Teaching Hospital (UVTH), University of Sydney, between 2001 and 2009 (n = 134) were compared with a control population of dogs seen in that period of time with a diagnosis other than lymphoma to evaluate association of explanatory variables (breed, age and sex) with the outcome (case or control status)...
May 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28444083/interictal-abnormal-fmri-activation-of-visual-areas-during-a-motor-task-cued-by-visual-stimuli-in-migraine
#4
Adriana Bastos Conforto, Khallil Taverna Chaim, Mario Fernando Prieto Peres, André Leite Gonçalves, Inara Laurindo Siqueira, Maria Angela Maramaldo Barreiros, Edson Amaro
Objective: To assess changes in blood-oxygen-level-dependent activity after light deprivation compared to regular light exposure in subjects with migraine in the interictal state and in controls. Methods: Ten subjects with migraine and ten controls participated in two sessions of functional magnetic resonance imaging. In each session, they performed a finger-tapping task with the right hand, cued by visual stimuli. They were scanned before and after 30 minutes of light deprivation or light exposure...
January 2017: Einstein
https://www.readbyqxmd.com/read/28444009/-antituberculosis-drug-resistance-in-the-border-of-brazil-with-paraguay-and-bolivia
#5
Marli Marques, Eunice Atsuko Totumi Cunha, Maria do Socorro Nantua Evangelista, Paulo Cesar Basta, Ana Maria Campos Marques, Julio Croda, Sonia Maria Oliveira de Andrade
Objective: To estimate the rate of drug resistance among pulmonary tuberculosis (PTB) cases in the state of Mato Grosso do Sul, Brazil, and specifically in the border areas with Paraguay and Bolivia, as well as to identify associated risk factors. Method: The present cross-sectional, epidemiological study focused on PTB cases recorded between January 2007 and December 2010 in the State Reportable Disease Information System with results of susceptibility tests to rifampicin, isoniazid, ethambutol, and streptomycin...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28444003/species-abundance-and-temporal-variation-of-arbovirus-vectors-in-brownsville-texas
#6
Krithika Srinivasan, Beatriz Tapia, Arturo Rodriguez, Robert Wood, Jennifer J Salinas
The recent outbreaks of the dengue fever and West Nile viruses and the looming threats of the Zika and chikungunya viruses highlight the importance of establishing effective, proactive arboviral surveillance in communities at high risk of transmission, such as those on the Texas-Mexico border. Currently, there are no approved human vaccines available for these mosquito-borne diseases, so entomological control and case management are the only known methods for decreasing disease incidence. The principal vectors, which include Culex quinquefasciatus, Aedes aegypti, and Ae...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28443647/identifying-and-modeling-the-structural-discontinuities-of-human-interactions
#7
Sebastian Grauwin, Michael Szell, Stanislav Sobolevsky, Philipp Hövel, Filippo Simini, Maarten Vanhoof, Zbigniew Smoreda, Albert-László Barabási, Carlo Ratti
The idea of a hierarchical spatial organization of society lies at the core of seminal theories in human geography that have strongly influenced our understanding of social organization. Along the same line, the recent availability of large-scale human mobility and communication data has offered novel quantitative insights hinting at a strong geographical confinement of human interactions within neighboring regions, extending to local levels within countries. However, models of human interaction largely ignore this effect...
April 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28443137/pediatric-urology-experience-in-canada-perspectives-from-south-of-the-border
#8
Jessica Ming, Jessica Hannick
No abstract text is available yet for this article.
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28443051/social-behavior-of-pet-dogs-is-associated-with-peripheral-oxtr-methylation
#9
Giulia Cimarelli, Zsófia Virányi, Borbála Turcsán, Zsolt Rónai, Mária Sasvári-Székely, Zsófia Bánlaki
Oxytocin is a key modulator of emotional processing and social cognitive function. In line with this, polymorphisms of genes involved in oxytocin signaling, like the oxytocin receptor (OXTR) gene, are known to influence social behavior in various species. However, to date, no study has investigated environmental factors possibly influencing the epigenetic variation of the OXTR gene and its behavioral effects in dogs. Pet dogs form individualized and strong relationships with their owners who are central figures in the social environment of their dogs and therefore might influence the methylation levels of their OXTR gene...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28443003/complementary-modular-microcircuits-of-the-rat-medial-entorhinal-cortex
#10
Saikat Ray, Andrea Burgalossi, Michael Brecht, Robert K Naumann
The parahippocampal region is organized into different areas, with the medial entorhinal cortex (MEC), presubiculum and parasubiculum prominent in spatial memory. Here, we also describe a region at the extremity of the MEC and bordering the subicular complex, the medial-most part of the entorhinal cortex. While the subdivisions of hippocampus proper form more or less continuous cell sheets, the superficial layers of the parahippocampal region have a distinct modular architecture. We investigate the spatial distribution, laminar position, and putative connectivity of zinc-positive modules in layer 2 of the MEC of rats and relate them to the calbindin-positive patches previously described in the entorhinal cortex...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28442849/operative-management-of-enteroatmospheric-fistula-in-bj%C3%A3-rck-4-open-abdomen-patients-by-the-help-of-laparoscopic-lateral-approach
#11
Fahri Yetişir, A Ebru Sarer
As the open abdomen (OA) management increases, the number of fistula formation has also been increasing during the last two decades. These fistulas in OA have been defined as enteroatmospheric fistula (EAF). EAF occurring in a frozen OA is classified as Björck 4 OA. Management of Björck 4 OA patient is not easy and mortality of these patients is very high in spite of the presence of modern treatment modalities. There are a few surgical approaches for treatment of Björck 4 OA patients. One of them is excising the hostile segment by lateral abdominal approach from the healthy side or entering from lateral border of OA wound after enough time intervals for subsiding of the edematous intestine in acute inflammatory reaction in the hostile environment...
April 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28442663/histochemical-assessment-for-osteoblastic-activity-coupled-with-dysfunctional-osteoclasts-in-c-src-deficient-mice
#12
Hisashi Toray, Tomoka Hasegawa, Naoko Sakagami, Erika Tsuchiya, Ai Kudo, Shen Zhao, Yasuhito Moritani, Miki Abe, Taiji Yoshida, Tomomaya Yamamoto, Tsuneyuki Yamamoto, Kimimitsu Oda, Nobuyuki Udagawa, Paulo Henrique Luiz de Freitas, Minqi Li
Since osteoblastic activities are believed to be coupled with osteoclasts, we have attempted to histologically verify which of the distinct cellular circumstances, the presence of osteoclasts themselves or bone resorption by osteoclasts, is essential for coupled osteoblastic activity, by examining c-fos(-/-) or c-src(-/-) mice. Osteopetrotic c-fos deficient (c-fos(-/-)) mice have no osteoclasts, while c-src deficient (c-src(-/-)) mice, another osteopetrotic model, develop dysfunctional osteoclasts due to a lack of ruffled borders...
2017: Biomedical Research
https://www.readbyqxmd.com/read/28441801/-prediction-of-occult-carcinoma-in-contralateral-nodules-based-on-the-ultrasonic-features-of-unilateral-papillary-thyroid-carcinoma
#13
L M Yang, Q Li, B W Zhao, J G Lyu, H S Xu, L L Xu, S Y Li, L Gao, J Zhu
Objective: To investigate the occurrence of occult carcinoma in contralateral lobes based on the ultrasonic features of unilateral papillary thyroid carcinoma. Methods: The study included 202 consecutives cases of unilateral papillary thyroid carcinoma with benign nodules in the contralateral lobe identified by preoperative ultrasound or fine-needle aspiration from June 2014 to December 2015. All patients received total thyroidectomies, and with postoperative pathological examination they were divided into two groups, one including 60 cases with positive occult cancer and another one consisting of 142 cases with negative occult cancer...
April 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28441749/using-wavelet-packet-transform-for-surface-roughness-evaluation-and-texture-extraction
#14
Xiao Wang, Tielin Shi, Guanglan Liao, Yichun Zhang, Yuan Hong, Kepeng Chen
Surface characterization plays a significant role in evaluating surface functional performance. In this paper, we introduce wavelet packet transform for surface roughness characterization and surface texture extraction. Surface topography is acquired by a confocal laser scanning microscope. Smooth border padding and de-noise process are implemented to generate a roughness surface precisely. By analyzing the high frequency components of a simulated profile, surface textures are separated by using wavelet packet transform, and the reconstructed roughness and waviness coincide well with the original ones...
April 23, 2017: Sensors
https://www.readbyqxmd.com/read/28441361/immunization-strategies-targeting-newly-arrived-migrants-in-non-eu-countries-of-the-mediterranean-basin-and-black-sea
#15
Cristina Giambi, Martina Del Manso, Maria Grazia Dente, Christian Napoli, Carmen Montaño-Remacha, Flavia Riccardo, Silvia Declich, Network For The Control Of Cross-Border Health Threats In The Mediterranean Basin And Black Sea For The ProVacMed Project
Background: The World Health Organization recommends that host countries ensure appropriate vaccinations to refugees, asylum seekers and migrants. However, information on vaccination strategies targeting migrants in host countries is limited. Methods: In 2015-2016 we carried out a survey among national experts from governmental bodies of 15 non-EU countries of the Mediterranean and Black Sea in order to document and share national vaccination strategies targeting newly arrived migrants. Results: Four countries reported having regulations/procedures supporting the immunization of migrants at national level, one at sub-national level and three only targeting specific population groups...
April 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28440952/thyroid-cancer-incidence-among-asian-immigrants-to-ontario-canada-a-population-based-cohort-study
#16
Baiju R Shah, Rebecca Griffiths, Stephen F Hall
BACKGROUND: The highest rates of thyroid cancer are observed in Pacific Island nations as well as Australia and Asian countries bordering the Pacific. The objective of this study was to determine the risk for thyroid cancer among immigrants to Canada from Southeast and East Asia compared with immigrants from other regions and nonimmigrants. METHODS: This was a population-based, longitudinal cohort study using health care administrative data to examine all residents of Ontario without pre-existing thyroid cancer...
April 25, 2017: Cancer
https://www.readbyqxmd.com/read/28440352/intrathyroidal-ectopic-thymus-in-children-a-sonographic-survey
#17
Adnan Kabaalioğlu, Murat Alp Öztek, Uğur Kesimal, Kağan Çeken, Emel Durmaz, Ali Apaydın
AIMS: Intrathyroidal ectopic thymus (IET) is being increasingly reported in the radiology literature. Most of the reports are of individual cases or small series and prevalence and natural course of the pathology is not well known. The purpose of this study is to establish the prevalence of IET in children and report long term follow-up results. MATERIAL AND METHODS: In 180 children who were examined by ultrasound (US) for other reasons, 7 patients were indentified with IET...
April 22, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28439966/automated-fractional-limb-volume-measurements-improve-the-precision-of-birth-weight-predictions-in-late-third-trimester-fetuses
#18
Lauren M Mack, Sung Yoon Kim, Sungmin Lee, Haleh Sangi-Haghpeykar, Wesley Lee
OBJECTIVES: Fetal soft tissue can be assessed by using fractional limb volume as a proxy for in utero nutritional status. We investigated automated fractional limb volume for rapid estimate fetal weight assessment. METHODS: Pregnant women were prospectively scanned for 2- and 3-dimensional fetal biometric measurements within 4 days of delivery. Performance of birth weight prediction models was compared: (1) Hadlock (Am J Obstet Gynecol 1985; 151:333-337; biparietal diameter, abdominal circumference, and femur diaphysis length); and (2) Lee (Ultrasound Obstet Gynecol 2009; 34:556-565; biparietal diameter, abdominal circumference, and automated fractional limb volume)...
April 25, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28439544/quantifying-the-negative-impact-of-brain-drain-on-the-integration-of-european-science
#19
Omar A Doria Arrieta, Fabio Pammolli, Alexander M Petersen
The 2004/2007 European Union (EU) enlargement by 12 member states offers a unique opportunity to quantify the impact of EU efforts to expand and integrate the scientific competitiveness of the European Research Area (ERA). We apply two causal estimation schemes to cross-border collaboration data extracted from millions of academic publications from 1996 to 2012, which are disaggregated across 14 subject areas and 32 European countries. Our results illustrate the unintended consequences following the 2004/2007 enlargement, namely, its negative impact on cross-border collaboration in science...
April 2017: Science Advances
https://www.readbyqxmd.com/read/28439236/auditory-visual-and-audiovisual-speech-processing-streams-in-superior-temporal-sulcus
#20
Jonathan H Venezia, Kenneth I Vaden, Feng Rong, Dale Maddox, Kourosh Saberi, Gregory Hickok
The human superior temporal sulcus (STS) is responsive to visual and auditory information, including sounds and facial cues during speech recognition. We investigated the functional organization of STS with respect to modality-specific and multimodal speech representations. Twenty younger adult participants were instructed to perform an oddball detection task and were presented with auditory, visual, and audiovisual speech stimuli, as well as auditory and visual nonspeech control stimuli in a block fMRI design...
2017: Frontiers in Human Neuroscience
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