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JOURNAL ARTICLE
Xynthia Kavelaars, Joris Mulder, Maurits Kaptein
The effects of treatments may differ between persons with different characteristics. Addressing such treatment heterogeneity is crucial to investigate whether patients with specific characteristics are likely to benefit from a new treatment. The current paper presents a novel Bayesian method for superiority decision-making in the context of randomized controlled trials with multivariate binary responses and heterogeneous treatment effects. The framework is based on three elements: a) Bayesian multivariate logistic regression analysis with a Pólya-Gamma expansion; b) a transformation procedure to transfer obtained regression coefficients to a more intuitive multivariate probability scale (i...
May 11, 2024: Multivariate Behavioral Research
#22
JOURNAL ARTICLE
Carlos Abril-Pérez, Miguel Mansilla-Polo, Begoña Escutia-Muñoz, Onofre Sanmartín, Joan R Garcés, Manuel A Rodríguez-Prieto, Verónica Ruiz-Salas, Esther de Eusebio-Murillo, Román Miñano-Medrano, Beatriz González-Sixto, Juan L Artola-Igarza, Alberto Alfaro-Rubio, Pedro Redondo, Yolanda Delgado-Jiménez, Julia M Sánchez-Schmidt, Irati Allende-Markixana, María L Alonso-Pacheco, Beatriz García-Bracamonte, Pablo de la Cueva-Dobao, Raquel Navarro-Tejedor, Cristina Ciudad-Blanco, Lucía Carnero-González, Hugo Vázquez-Veiga, Natividad Cano-Martínez, Carlos Serra-Guillén, Eva Vilarrasa, Pedro Sánchez-Sambucety, José L López-Estebaranz, Ángeles Flórez-Menéndez, Antonio Martorell-Calatayud, Pilar Gil, Victoriano Morales-Gordillo, Agustí Toll, Izascun Ocerin-Guerra, Matías Mayor-Arenal, Ricardo Suárez-Fernández, Laura Sainz-Gaspar, Miguel A Descalzo, Ignacio Garcia-Doval, Rafael Botella-Estrada
BACKGROUND: Immunosuppressed (IS) patients, particularly solid organ transplant recipients and those on immunosuppressive therapy, face a higher incidence and recurrence of nonmelanoma skin cancers (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Mohs micrographic surgery (MMS) is the preferred treatment for high-risk NMSC due to its high cure rate and margin examination capabilities. However, IS patients may experience more complications, such as surgical site infections, and a greater risk of recurrence, making their outcomes a subject of interest...
May 11, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#23
JOURNAL ARTICLE
Lucinda Ballantyne
Patients enter states that in their spontaneity and deep interiority have qualities of the revelatory. I propose we recognize such a state as a clinical event: The person is in a state of intense internal receiving of self. We might think of it as a state of internal communication happening as the person speaks. The person feels real to herself. Her relation to her mind in this revelatory moment is easily intruded on-even by ventures of play. When the state is gone, it is gone. I single out this clinical moment from moments that are cocreated and happening within an analytic third...
May 11, 2024: Journal of the American Psychoanalytic Association
#24
JOURNAL ARTICLE
Chi-Chun Tseng, Kuang-Chieh Wang, Po-Shen Lin, Chi Chang, Li-Lun Yeh, Shih-Huang Tung, Cheng-Liang Liu, Yen-Ju Cheng
While research on organic thermoelectric polymers is making significant progress in recent years, realization of a single polymer material possessing both thermoelectric properties and stretchability for the next generation of self-powered wearable electronics is a challenging task and remains an area yet to be explored. A new molecular engineering concept of "conjugated breaker" is employed to impart stretchability to a highly crystalline diketopyrrolepyrrole (DPP)-based polymer. A hexacyclic diindenothieno[2,3-b]thiophene (DITT) unit, with two 4-octyloxyphenyl groups substituted at the tetrahedral sp3-carbon bridges, is selected to function as the conjugated breaker that can sterically hinder intermolecular packing to reduce polymers' crystallinity...
May 11, 2024: Small
#25
JOURNAL ARTICLE
Claudia A Martin, Eleanor C Sheppard, Hisham A A Ali, Juan Carlos Illera, Alexander Suh, Lewis G Spurgin, David S Richardson
When populations colonise new environments, they may be exposed to novel selection pressures but also suffer from extensive genetic drift due to founder effects, small population sizes and limited interpopulation gene flow. Genomic approaches enable us to study how these factors drive divergence, and disentangle neutral effects from differentiation at specific loci due to selection. Here, we investigate patterns of genetic diversity and divergence using whole-genome resequencing (>22× coverage) in Berthelot's pipit (Anthus berthelotii), a passerine endemic to the islands of three north Atlantic archipelagos...
May 11, 2024: Molecular Ecology
#26
JOURNAL ARTICLE
Jonas Wilkman, Jan Antfolk, Julia Korkman
The increase in remote hearings after the COVID-19 pandemic presents an urgent need to examine how judges assess video-mediated witness and party statements compared with live statements. There is currently a limited body of research on this subject. As for the assessment itself, professionals within the judicial system sometimes believe they can detect deception based on visible cues such as body language and emotional expression. Research has, however, shown that lies cannot be detected based on such cues...
May 11, 2024: Scandinavian Journal of Psychology
#27
JOURNAL ARTICLE
Kiran R, Princy A, Masilla S Moses Kennedy, Mohammad I Sayyed, Vikash Mishra, Sudha D Kamath
Ultra-high thermally stable Ca2 MgWO6 :xSm3+ (x = 0.5, 0.75, 1, 1.25, and 1.5 mol%) double perovskite phosphors were synthesized through solid-state reaction method. Product formation was confirmed by comparing the X-ray diffraction (XRD) patterns of the phosphors with the standard reference file. The structural, morphological, thermal, and optical properties of the prepared phosphor were examined in detail using XRD, Fourier transform infrared spectra, scanning electron microscopy, diffused reflectance spectra, thermogravimetric analysis (TGA), photoluminescence emission, and temperature-dependent PLE (TDPL)...
May 2024: Luminescence: the Journal of Biological and Chemical Luminescence
#28
JOURNAL ARTICLE
F Bafageeh, T Loux
BACKGROUND: Individuals with mental illness have poor oral health compared to those without mental health conditions. However, the literature is still lacking regarding the specifics of this relationship. OBJECTIVE: This study aims at examining the relationship between depression and oral health problems such as oral conditions, access to dental care, and oral hygiene measures. METHODS: A cross-sectional study using a secondary data analysis of 9,693 participants from the 2017 to March 2020 prepandemic National Health and Nutrition Examination Survey (NHANES)...
May 10, 2024: JDR Clinical and Translational Research
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JOURNAL ARTICLE
Brian Southwell, Sula Hood, Javan Carter, Courtney Richardson, Sheri Cates, Hadyatoullaye Sow, MaryBeth Branigan, Trey-Rashad Hawkins, Katie Atkinson, Jennifer Uhrig, Megan Lewis
PURPOSE: The aim of this study was to describe opportunities and challenges associated with the development and implementation of a program for supporting researchers underrepresented in biomedical research. APPROACH: We describe a case study of the All of Us Researcher Academy supported by the National Institutes of Health (NIH), including feedback from participants, instructors, and coaches. FINDINGS: Lessons include the importance of inviting role models into learning networks, establishing and maintaining trusted relationships, and making coaches available for technical questions from researcher participants...
May 10, 2024: Journal of the American Medical Informatics Association: JAMIA
#30
JOURNAL ARTICLE
Daniel Freinhofer, Philipp Schwartenbeck, Natasha Thon, Wolfgang Aichhorn, Melanie Lenger, Friedrich M Wurst, Martin Kronbichler
Impaired decision-making is often displayed by individuals suffering from gambling disorder (GD). Since there are a variety of different phenomena influencing decision-making, we focused in this study on the effects of GD on neural and behavioural processes related to loss aversion and choice difficulty. Behavioural responses as well as brain images of 23 patients with GD and 20 controls were recorded while they completed a mixed gambles task, where they had to decide to either accept or reject gambles with different amounts of potential gain and loss...
May 2024: Addiction Biology
#31
JOURNAL ARTICLE
Karin Kee, Marieke van Wieringen, Henk Nies, Bianca Beersma
AIM: Whereas voice behaviour has been identified as a key precursor to safe and high-quality patient care, little is known about how voice relates to key workforce outcomes. This study aimed to investigate the relationships between certified nursing assistants' perceived promotive voice behaviour (speaking up with suggestions for future improvement) and prohibitive voice behaviour (speaking up about problems or potentially harmful situations) and their self-reported levels of job satisfaction, work engagement and turnover intentions...
May 10, 2024: Journal of Advanced Nursing
#32
JOURNAL ARTICLE
Marie Danielle Le Lagadec, Deb Massey, Amy-Louise Byrne, Justine Connor, Tracy Flenady
AIM: To evaluate registered nurses' perceptions of whether the mandated use of the early warning system vital signs tool impacts the development of nurses' higher-order thinking skills. DESIGN: A concurrent mixed methods study design. METHOD: Using an online survey, registered nurses' perceptions were elucidated on whether early warning system algorithmic tools affected the development of their higher-order thinking. Likert-type matrix questions with additional qualitative fields were used to obtain information on nurse's perceptions of the tool's usefulness, clinical confidence in using the tool, compliance with escalation protocols, work environment and perceived compliance barriers...
May 10, 2024: Journal of Advanced Nursing
#33
JOURNAL ARTICLE
Christoph S Aigner, Manuel F Sánchez Alarcon, Alexandre D'Astous, Eva Alonso-Ortiz, Julien Cohen-Adad, Sebastian Schmitter
PURPOSE: To address the limitations of spinal cord imaging at ultra-high field (UHF) due to time-consuming parallel transmit (pTx) adjustments. This study introduces calibration-free offline computed universal shim modes that can be applied seamlessly for different pTx RF coils and spinal cord target regions, substantially enhancing spinal cord imaging efficiency at UHF. METHODS: A library of channel-wise relative <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow><mml:msubsup><mml:mi>B</mml:mi> <mml:mn>1</mml:mn> <mml:mo>+</mml:mo></mml:msubsup> </mml:mrow> <mml:annotation>$$ {B}_1^{+} $$</mml:annotation></mml:semantics> </mml:math> maps for the cervical spinal cord (six datasets) and thoracic and lumbar spinal cord (nine datasets) was constructed to optimize transmit homogeneity and efficiency for these regions...
May 10, 2024: Magnetic Resonance in Medicine
#34
JOURNAL ARTICLE
Syed M Arshad, Lee C Potter, Chong Chen, Yingmin Liu, Preethi Chandrasekaran, Christopher Crabtree, Matthew S Tong, Orlando P Simonetti, Yuchi Han, Rizwan Ahmad
PURPOSE: To present and assess an outlier mitigation method that makes free-running volumetric cardiovascular MRI (CMR) more robust to motion. METHODS: The proposed method, called compressive recovery with outlier rejection (CORe), models outliers in the measured data as an additive auxiliary variable. We enforce MR physics-guided group sparsity on the auxiliary variable, and jointly estimate it along with the image using an iterative algorithm. For evaluation, CORe is first compared to traditional compressed sensing (CS), robust regression (RR), and an existing outlier rejection method using two simulation studies...
May 10, 2024: Magnetic Resonance in Medicine
#35
JOURNAL ARTICLE
Partha Sarati Das, Daniella Skaf, Lina Rose, Fatemeh Motaghedi, Tricia Breen Carmichael, Simon Rondeau-Gagné, Mohammed Jalal Ahamed
Gait phase monitoring wearable sensors play a crucial role in assessing both health and athletic performance, offering valuable insights into an individual's gait pattern. In this study, we introduced a simple and cost-effective capacitive gait sensor manufacturing approach, utilizing a micropatterned polydimethylsiloxane dielectric layer placed between screen-printed silver electrodes. The sensor demonstrated inherent stretchability and durability, even when the electrode was bent at a 45-degree angle, it maintained an electrode resistance of approximately 3 Ω...
May 6, 2024: Sensors
#36
JOURNAL ARTICLE
Sharafat Ali, Fakhrul Alam, Johan Potgieter, Khalid Mahmood Arif
Low-cost ambient sensors have been identified as a promising technology for monitoring air pollution at a high spatio-temporal resolution. However, the pollutant data captured by these cost-effective sensors are less accurate than their conventional counterparts and require careful calibration to improve their accuracy and reliability. In this paper, we propose to leverage temporal information, such as the duration of time a sensor has been deployed and the time of day the reading was taken, in order to improve the calibration of low-cost sensors...
May 4, 2024: Sensors
#37
JOURNAL ARTICLE
Norbert Serban, David Kupas, Andras Hajdu, Peter Török, Balazs Harangi
Performing a minimally invasive surgery comes with a significant advantage regarding rehabilitating the patient after the operation. But it also causes difficulties, mainly for the surgeon or expert who performs the surgical intervention, since only visual information is available and they cannot use their tactile senses during keyhole surgeries. This is the case with laparoscopic hysterectomy since some organs are also difficult to distinguish based on visual information, making laparoscope-based hysterectomy challenging...
May 4, 2024: Sensors
#38
JOURNAL ARTICLE
Justin Ivancic, Fabio Alves
This paper reports on the design, modeling, and characterization of a multi-resonant, directional, MEMS acoustic sensor. The design builds on previous resonant MEMS sensor designs to broaden the sensor's usable bandwidth while maintaining a high signal-to-noise ratio (SNR). These improvements make the sensor more attractive for detecting and tracking sound sources with acoustic signatures that are broader than discrete tones. In-air sensor characterization was conducted in an anechoic chamber. The sensor was characterized underwater in a semi-anechoic pool and in a standing wave tube...
May 2, 2024: Sensors
#39
REVIEW
Meiqing Jin, Peizheng Shi, Zhuang Sun, Ningbin Zhao, Mingjiao Shi, Mengfan Wu, Chen Ye, Cheng-Te Lin, Li Fu
Recent advancements in polymer-assisted layer-by-layer (LbL) fabrication have revolutionized the development of wearable sensors for health monitoring. LbL self-assembly has emerged as a powerful and versatile technique for creating conformal, flexible, and multi-functional films on various substrates, making it particularly suitable for fabricating wearable sensors. The incorporation of polymers, both natural and synthetic, has played a crucial role in enhancing the performance, stability, and biocompatibility of these sensors...
May 1, 2024: Sensors
#40
REVIEW
Minjae Kang, Sungbin Park, Yeonjoon Lee
In recent years, satellite communication systems (SCSs) have rapidly developed in terms of their role and capabilities, promoted by advancements in space launch technologies. However, this rapid development has also led to the emergence of significant security vulnerabilities, demonstrated through real-world targeted attacks such as AcidRain and AcidPour that demand immediate attention from the security community. In response, various countermeasures, encompassing both technological and policy-based approaches, have been proposed to mitigate these threats...
May 1, 2024: Sensors
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