keyword
MENU ▼
Read by QxMD icon Read
search

Adults

keyword
https://www.readbyqxmd.com/read/29166740/-factors-associated-with-early-treatment-response-in-adults-with-acute-myeloid-leukemia
#1
X Ren, T Zhao, J Wang, H H Zhu, H Jiang, J S Jia, S M Yang, B Jiang, D B Wang, X J Huang, Q Jiang
Objective: To explore the factors influencing early treatment responses in adult with de novo acute myeloid leukemia (AML) . Methods: Data of consecutive newly-diagnosed AML (non-acute promyelocytic leukemia) adults were analyzed retrospectively. To assess the impact of clinical characteristics at diagnosis and induction regimen on achieving morphologic leukemia-free state (MLFS) , blood counts and minimal residual leukemia (MRD, positive MRD defined as RQ-PCR WT1 mRNA ≥0.6% and/or any level of abnormal blast population detected by flow cytometry) at the time of achieving MLFS...
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166695/-without-net-and-double-floor-comparison-of-umbilical-hernia-repair-by-spitzy-in-children-and-adults
#2
Laura Kuck, Florian Seitz, Armin Wiegering, Ulrich Dietz, Thomas Meyer
Summary Umbilical hernia occur in both adults and children. For over 100 years, umbilical hernia in children has been treated surgically by the Spitzy method. With adult patients, meshes are being increasingly used. The purpose of our study was to analyse Spitzy herniotomy with respect to the recurrence rate in children and adults. Material and Methods Over a period of 7 years, 383 children (age < 16 years) with umbilical hernia were treated surgically; after applying the exclusion criteria, 370 patients were evaluated...
November 22, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29166658/episodic-future-thinking-reduces-temporal-discounting-in-healthy-adolescents
#3
Uli Bromberg, Maria Lobatcheva, Jan Peters
Episodic Future Thinking has proven efficient in reducing impulsive behavior in several adult populations. Whether it also has a beneficial impact on decision making in adolescents is not known. Here the impact of episodic future thinking on discounting behavior was investigated in a sample of healthy adolescents (n = 44, age range 13-16 years). Discounting behavior in trials including episodic future thinking was significantly less impulsive than in control trials (t = 2.74, p = .009, dz = .44). In a subsample we controlled for executive function, alcohol use and developmental measures...
2017: PloS One
https://www.readbyqxmd.com/read/29166615/olfactory-experience-and-developmental-stage-dependent-control-of-cpeb4-regulates-c-fos-mrna-translation-for-granule-cell-survival
#4
Ching-San Tseng, Hsu-Wen Chao, Hsien-Sung Huang, Yi-Shuian Huang
Mammalian olfactory bulbs (OBs) require continuous replenishment of interneurons (mainly granule cells [GCs]) to support local circuits throughout life. Two spatiotemporally distinct waves of postnatal neurogenesis contribute to expanding and maintaining the GC pool. Although neonate-born GCs have a higher survival rate than adult-born GCs, the molecular mechanism underlying this survival remains unclear. Here, we find that cytoplasmic polyadenylation element-binding protein 4 (CPEB4) acts as a survival factor exclusively for early postnatal GCs...
November 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/29166614/critical-modulation-of-hematopoietic-lineage-fate-by-hepatic-leukemia-factor
#5
Martin Wahlestedt, Vasileios Ladopoulos, Isabel Hidalgo, Manuel Sanchez Castillo, Rebecca Hannah, Petter Säwén, Haixia Wan, Monika Dudenhöffer-Pfeifer, Mattias Magnusson, Gudmundur L Norddahl, Berthold Göttgens, David Bryder
A gradual restriction in lineage potential of multipotent stem/progenitor cells is a hallmark of adult hematopoiesis, but the underlying molecular events governing these processes remain incompletely understood. Here, we identified robust expression of the leukemia-associated transcription factor hepatic leukemia factor (Hlf) in normal multipotent hematopoietic progenitors, which was rapidly downregulated upon differentiation. Interference with its normal downregulation revealed Hlf as a strong negative regulator of lymphoid development, while remaining compatible with myeloid fates...
November 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/29166613/niche-cadherins-control-the-quiescence-to-activation-transition-in-muscle-stem-cells
#6
Aviva J Goel, Marysia-Kolbe Rieder, Hans-Henning Arnold, Glenn L Radice, Robert S Krauss
Many adult stem cells display prolonged quiescence, promoted by cues from their niche. Upon tissue damage, a coordinated transition to the activated state is required because non-physiological breaks in quiescence often lead to stem cell depletion and impaired regeneration. Here, we identify cadherin-mediated adhesion and signaling between muscle stem cells (satellite cells [SCs]) and their myofiber niche as a mechanism that orchestrates the quiescence-to-activation transition. Conditional removal of N-cadherin and M-cadherin in mice leads to a break in SC quiescence, with long-term expansion of a regeneration-proficient SC pool...
November 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/29166532/description-of-fourth-instar-larva-and-pupa-of-atrichopogon-delpontei-cavalieri-and-chiossone-diptera-ceratopogonidae-from-brazilian-amazonia
#7
Pablo I Marino, Gustavo R Spinelli, Ruth Ferreira-Keppler, María M Ronderos
The fourth instar larva and pupa of Atrichopogon delpontei Cavalieri and Chiossone are described for the first time. The immatures were collected from stream margins in the northern Brazilian states Rondônia and Piauí, and subsequently reared to adults. Larvae and pupae are illustrated and photomicrographed. Details on the rearing process and feeding behavior in laboratory, bionomics and notes on habitats are also provided.
2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29166507/pigmented-bowen-s-disease-associated-with-high-risk-hpv-simulating-melanoma-of-the-hand
#8
Rute Facchini Lellis, John Verrinder Veasey, Renata Diniz Jacques Gonçalves
Bowen's disease is an in situ squamous cell carcinoma of the skin with only 2% of pigmented cases reported. It is clinically characterized by papules and plaques of blackened surface that may be caused either by sun damage - usually in photoexposed areas in elderly individuals - or by human papillomavirus infection - usually in the anogenital region of young adults. Dermoscopic aspects of Bowen's disease are discussed for over a decade, but with no definitive criteria that would lead to a definitive diagnosis...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166501/primary-cutaneous-t-cell-lymphoma-experience-from-the-peruvian-national-cancer-institute
#9
Rosana Ruiz, Zaida Morante, Raul Mantilla, Luis Mas, Luis Casanova, Henry L Gomez
BACKGROUND: Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America. OBJECTIVE: To determine the clinicopathological features, relative frequency and survival among patients from a Peruvian institution. METHODS: Primary cutaneous T-cell lymphomas were defined based on the absence of extracutaneous disease at diagnosis. Classification was performed following the 2008 World Health Organization Classification of Neoplasms of the Hematopoietic and Lymphoid tissues...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166496/recurrent-aphthous-stomatitis-in-18-year-old-adolescents-prevalence-and-associated-factors-a-population-based-study
#10
Paulo Ricardo Martins de Souza, Rodrigo Pereira Duquia, Juliano de Avelar Breunig, Hiram Larangeira de Almeida
BACKGROUND: Recurrent aphthous stomatitis is a painful disorder of unknown etiology. It is among the most common oral mucosal lesions with high prevalence among young adults. OBJECTIVES: To conduct a population-based study with 18-year-old army recruiters to assess its prevalence and associated factors in male adolescents. METHODS: Interview during clinical examination in the army. RESULTS: In this group (2,427 interviewed adolescents) there was a RAS prevalence of 24...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166488/income-inequality-and-high-blood-pressure-in-colombia-a-multilevel-analysis
#11
Diego I Lucumi, Amy J Schulz, Ana V Diez Roux, Andrew Grogan-Kaylor
The objective of this research was to examine the association between income inequality and high blood pressure in Colombia. Using a nationally representative Colombian sample of adults, and data from departments and municipalities, we fit sex-stratified linear and logistic multilevel models with blood pressure as a continuous and binary variable, respectively. In adjusted models, women living in departments with the highest quintile of income inequality in 1997 had higher systolic blood pressure than their counterparts living in the lowest quintile of income inequality (mean difference 4...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29166473/-frequency-and-variables-associated-with-perceived-devaluation-discrimination-in-victims-of-the-armed-conflict-in-colombia
#12
Adalberto Campo-Arias, Anyelly C Ospino, Adriana R Sanabria, Valeria M Guerra, Beatriz H Caamaño, Edwin Herazo
There is no information on frequency of perceived devaluation-discrimination in victims of the armed conflict in Colombia. The aim of this study was thus to determine the frequency of perceived devaluation-discrimination and associated variables among victims of the armed conflict in municipalities in the Department of Magdalena, Colombia. A cross-sectional study was conducted among victims enrolled in the Program for Psychosocial Care and Comprehensive Healthcare for Victims. Depressive symptoms were quantified with four dichotomous items (three or more were classified as high level of depressive symptoms), and perceived devaluation-discrimination was quantified with six dichotomous items (two or more were classified as high perceived devaluation-discrimination)...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29166462/effects-of-an-alternating-work-shift-on-air-traffic-controllers-and-the-relationship-with-excessive-daytime-sleepiness-and-stress
#13
Ângela M Freitas, Mirna Wetters Portuguez, Thaís Russomano, Marcos de Freitas, Silvio Luis da Silva Silvello, Jaderson Costa da Costa
OBJECTIVE: To evaluate symptoms of stress and excessive daytime sleepiness (EDS) in air traffic control (ATC) officers in Brazil. METHODS: Fifty-two ATC officers participated, based at three air traffic control units, identified as A, B and C. Stress symptoms were assessed using the Lipp Inventory of Stress Symptoms for Adults, and EDS by the Epworth Sleepiness Scale. RESULTS: The sample mean age was 37 years, 76.9% of whom were male. Excessive daytime sleepiness was identified in 25% of the ATC officers, with 84...
October 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29166451/factors-associated-with-frailty-in-a-community-dwelling-population-of-older-adults
#14
Danielle Teles da Cruz, Marcel de Toledo Vieira, Ronaldo Rocha Bastos, Isabel Cristina Gonçalves Leite
OBJECTIVE: To analyze if demographic and socioeconomic factors and factors related to health and health services are associated with frailty in community-dwelling older adults. METHODS: This is a cross-sectional study with 339 older adults (60 years old or more) living in Juiz de Fora, State of Minas Gerais, Brazil, in 2015. A household survey was carried out and frailty was evaluated using the Edmonton Frail Scale. For the analysis of the factors associated with outcome, a theoretical model of determination was constructed with three hierarchical blocks: block 1 with demographic and socioeconomic characteristics, block 2 with the health of the older adult (divided into three sub-levels: 2...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166447/prevalence-and-clinical-profile-of-chronic-pain-and-its-association-with-mental-disorders
#15
Flávia Garcia Pereira, Mariane Henriques França, Maria Cristina Alochio de Paiva, Laura Helena Andrade, Maria Carmen Viana
OBJECTIVE: To identify the prevalence of 12-month self-reported pain and chronic pain in a general population and to describe their clinical profile to assess if chronic pain is associated with 12-month mental disorders. METHODS: The data used comes from the São Paulo Megacity Mental Health Survey, a population-based study assessing adult (≥ 18 years) residents of the São Paulo metropolitan area, Brazil. We have assessed the respondents (n = 5,037) using the Composite International Diagnostic Interview (CIDI 3...
November 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166445/regular-access-and-adherence-to-medications-of-the-specialized-component-of-pharmaceutical-services
#16
Janaína Soder Fritzen, Fabiane Raquel Motter, Vera Maria Vieira Paniz
OBJECTIVE: To investigate the prevalence of the adherence to the medications of the Specialized Component of Pharmaceutical Services and its association with regular access in users of these medications in the municipality of São Leopoldo, State of Rio Grande do Sul, Brazil. METHODS: This is a cross-sectional study with adults aged 20 years and over, who are users of medications of the Specialized Component of Pharmaceutical Services. Sampling was carried out consecutively for users who accessed the service of the Specialized Component of Pharmaceutical Services during the period from December 2014 to March 2015...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166443/epifloripa-aging-cohort-study-methods-operational-aspects-and-follow-up-strategies
#17
Ione Jayce Ceola Schneider, Susana Cararo Confortin, Carla de Oliveira Bernardo, Carolina Carvalho Bolsoni, Danielle Ledur Antes, Karine Gonçalves Pereira, Lariane Mortean Ono, Larissa Pruner Marques, Lucélia Justino Borges, Maruí Weber Corseuil Giehl, Rodrigo de Rosso Krug, Vanessa Fernanda Goes, Alexandra Crispim Boing, Antônio Fernando Boing, Eleonora d'Orsi
OBJECTIVE: To describe the sample plan, operational aspects, and strategies used in the 2009/2010 and 2013/2014 EpiFloripa Aging Study. METHODS: The EpiFloripa Aging is a population-based longitudinal study with 1,705 older adults (60 years or more) living in the municipality of Florianópolis, State of Santa Catarina, Brazil, in 2009/2010 (baseline). The research was conducted with a face-to-face interviews, organized into blocks of identification, socioeconomic, mental health, health and life habits, global functionality, falls, physical activity, morbidities, use of health services, use of medications, food, oral health, and violence, evaluated in the first (2009/2010) and in the second wave (2013/2014)...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166438/prevalence-and-risk-factors-of-inadequate-medicine-home-storage-a-community-based-study
#18
Rand Randall Martins, Andreza Duarte Farias, Yonara Monique da Costa Oliveira, Rodrigo Dos Santos Diniz, Antonio Gouveia Oliveira
OBJECTIVE: Assess the extent of inadequate home storage of medicines andidentify important risk factors. METHODS: A cross-sectional survey based on a probability sample in the community, conducted in 267 households in Cuité, State of Paraíba, Northeast Brazil, in 2014. Logistic regression was used to study the risk factors. RESULTS: The prevalence of households with inadequate storage was 76.0%. Problems with storage include direct exposure to sunlight in 10...
November 17, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29166408/estimating-the-impact-of-tuberculosis-anatomical-classification-on-treatment-outcomes-a-patient-and-surveillance-perspective-analysis
#19
Otavio T Ranzani, Laura C Rodrigues, Eliseu A Waldman, Carlos R R Carvalho
INTRODUCTION: Tuberculosis anatomical classification is inconsistent in the literature, which limits current tuberculosis knowledge and control. We aimed to evaluate whether tuberculosis classification impacts on treatment outcomes at patient and aggregate level. METHODS: We analyzed adults from São Paulo State, Brazil with newly diagnosed tuberculosis from 2010-2013. We used an extended clinical classification of tuberculosis, categorizing cases as pulmonary, pulmonary and extrapulmonary, extrapulmonary and miliary/disseminated...
2017: PloS One
https://www.readbyqxmd.com/read/29166393/implicit-theories-concerning-the-intelligence-of-individuals-with-down-syndrome
#20
Claire Enea-Drapeau, Michèle Carlier, Pascal Huguet
Studies over the past three decades have shown that learning difficulties are not only determined by neurological disorders, but also by motivational and/or socio-cognitive factors Among these factors, implicit theories of intelligence (also referred to as conceptions, mindsets or beliefs about intelligence) are key elements. The belief that intelligence is fixed (entity theory), as opposed to malleable (incremental theory), is generally associated with negative teaching practices and poorer student outcomes, yet beliefs about the intelligence of individuals with intellectual disabilities have not received much attention...
2017: PloS One
keyword
keyword
39825
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"