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https://www.readbyqxmd.com/read/28637032/investigation-of-an-immediate-effect-of-bright-light-on-oxygen-consumption-heart-rate-cortisol-and-%C3%AE-amylase-in-seasonal-affective-disorder-subjects-and-healthy-controls
#1
Iana A Ivanova, Konstantin V Danilenko, Lyubomir I Aftanas
BACKGROUND: Body (fat) mass has been shown to decrease following bright light treatment for overweight women, irrespective of their seasonal (light) dependence. It is not known if this is due to an (immediate) increase of metabolism. METHODS: Ten women with seasonal affective disorder (SAD) and 10 non-SAD women matched by age, body mass index, and menopausal status participated in a laboratory study in the morning, twice within 1-5 days. During one session, bright light (4,300 lx) was presented for 30 min, and during the other session, red light (250 lx "placebo") was used...
June 22, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28636647/hemodynamic-and-metabolic-characteristics-associated-with-development-of-a-right-ventricular-outflow-tract-pressure-gradient-during-upright-exercise
#2
Annelieke C M J van Riel, David M Systrom, Rudolf K F Oliveira, Michael J Landzberg, Barbara J M Mulder, Berto J Bouma, Bradley A Maron, Amil M Shah, Aaron B Waxman, Alexander R Opotowsky
BACKGROUND: We recently reported a novel observation that many patients with equal resting supine right ventricular(RV) and pulmonary artery(PA) systolic pressures develop an RV outflow tract(RVOT) pressure gradient during upright exercise. The current work details the characteristics of patients who develop such an RVOT gradient. METHODS: We studied 294 patients (59.7±15.5 years-old, 49% male) referred for clinical invasive cardiopulmonary exercise testing, who did not have a resting RVOT pressure gradient defined by the simultaneously measured peak-to-peak difference between RV and PA systolic pressures...
2017: PloS One
https://www.readbyqxmd.com/read/28634587/exercise-metabolism-in-nonobese-patients-with-type-2-diabetes-following-the-acute-restoration-of-normoglycaemia
#3
Christopher J Gaffney, Peter Mansell, Francis B Stephens, Ian A Macdonald, Kostas Tsintzas
This study investigated how acute restoration of normoglycaemia affected energy metabolism during exercise in nonobese patients with type 2 diabetes. Six subjects (mean ± SEM) aged 56.2 ± 2.7 years, with a BMI of 24.5 ± 1.5 kg/m(2) and a VO2 peak of 28.7 ml/kg/min, attended the lab on two randomised occasions for a four-hour resting infusion of insulin or saline, followed by 30 minutes cycling at 50% VO2 peak. During the 4 h resting infusion, there was a greater (P < 0.0001) reduction in blood glucose in insulin treatment (INS) (from 11...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28633495/estradiol-protects-against-cardio-respiratory-dysfunctions-and-oxidative-stress-in-intermittent-hypoxia
#4
Sofien Laouafa, Alexandra Ribon-Demars, François Marcouiller, Damien Roussel, Aida Bairam, Vincent Pialoux, Vincent Joseph
Study Objectives: We tested the hypothesis that estradiol (E2) protects against cardio-respiratory disorders and oxidative stress induced by chronic intermittent hypoxia (CIH) in adult female rats. Methods: Sprague-Dawley female rats (230-250g) were ovariectomized (OVX) and implanted with osmotic pumps delivering vehicle (Veh) or E2 (0.5 mg/kg/day). After 14 days of recovery, the rats were exposed to chronic CIH (21%-10% O2 - 8 hours/day - 10 cycles/hour) or room air (RA)...
June 19, 2017: Sleep
https://www.readbyqxmd.com/read/28633001/impact-of-4-weeks-of-interval-training-on-resting-metabolic-rate-fitness-and-health-related-outcomes
#5
Matthew M Schubert, Holly E Clarke, Rebekah F Seay, Katie K Spain
PURPOSE: Resting metabolic rate (RMR) and substrate oxidation (RER) are important indicators of health. The effects of interval training on RMR have not been thoroughly investigated, which was the purpose of the present study. METHODS: Thirty men and women (mean ± SD age and VO2max: 28.8 ± 7.6 yrs and 33.0 ± 8.3 mL∙kg-1∙min-1) completed 4 weeks of Wingate-based sprint interval training (SIT), repeated 1-minute high-intensity intervals (HIIT), or served as controls (CON)...
June 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28631701/-clinical-features-of-osteoarthritis-in-patients-with-metabolic-syndrome
#6
L V Vasilyeva, D I Lakhin
AIM: To estimate clinical and laboratory parameters in patients with osteoarthritis (OA) and in those with OA and metabolic syndrome (MS). SUBJECTS AND METHODS: 164 patients with OA were examined and divided into 2 groups of 82 people: a study group (patients with MS) and a control one (those without MS). OA was defined according to the diagnostic criteria described by R.D. Althmann (1995). MS was identified based on the criteria developed by the International Diabetes Federation (2005)...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28630580/the-effect-of-upper-body-anaerobic-pre-loading-on-2000-m-ergometer-rowing-performance-in-college-level-male-rowers
#7
Priit Purge, Peter Hofmann, Rait Merisaar, Alexander Mueller, Gerhard Tschakert, Jarek Mäestu, Jaak Jürimäe
Elevated blood lactate has been shown to influence subsequent anaerobic exercise due to an inhibition of glycolysis. The aim of the present study was therefore to investigate the influence of a short and high-intensity anaerobic arm crank pre-load exercise (HIE) added to a low-intensity warm-up on cardio-respiratory and metabolic responses on a subsequent all out rowing exercise. Nine well-trained college level male rowers (24.6 ± 7.1 yrs; 1.87 ± 0.07 m; 88.9 ± 9.8 kg; 18.5 ± 3.7% body fat) volunteered to participate in the study...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28628125/enhanced-insulin-sensitivity-in-successful-long-term-weight-loss-maintainers-compared-with-matched-controls-with-no-weight-loss-history
#8
L D Clamp, D J Hume, E V Lambert, J Kroff
BACKGROUND: Weight gain is associated with deterioration in metabolic health, whereas weight loss improves insulin sensitivity. This study assesses the impact of long-term, successfully maintained weight loss and weight-loss relapse on measures of insulin sensitivity and identifies factors that explain variability in insulin sensitivity. METHODS: Women (20-45 years) were recruited into four groups: reduced-overweight/obese (RED, n=15); body mass index (BMI)-matched controls (stable low-weight, n=19), BMI⩽27 kg m(-2); relapsed-overweight/obese subjects (REL, n=11); and BMI-matched controls (obese stable weight, n=11), BMI⩾27 kg m(-2)...
June 19, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28627208/irisin-is-weakly-associated-with-usual-physical-activity-in-young-overweight-women
#9
Beatriz Tenorio, Teresa Jiménez, Gladys Barrera, Sandra Hirsch, Maria Pia De la Maza, Rodrigo Troncoso, María Belén Farias, Juan Manuel Rodríguez, Daniel Bunout
PURPOSE: To determine if irisin plasma levels are associated with regular physical activity, body composition and metabolic parameters in women subjected to calorie restriction. SUBJECTS AND METHODS: We studied 42 women aged 34 ± 13 years with a body mass index of 27.7 ± 1.8 kg/m2, who were subjected to a calorie restriction for three months. At baseline and at the end of the study, weight, waist and hip circumference, laboratory parameters, body composition by DEXA, resting and activity energy expenditure by indirect calorimetry and 72 hours actigraphy were measured...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626157/protein-restriction-does-not-affect-body-temperature-pattern-in-female-mice
#10
Goro A Kato, Hiroki Shichijo, Toshihiro Takahashi, Akio Shinohara, Tetsuo Morita, Chihiro Koshimoto
Daily torpor is a physiological adaptation in mammals and birds characterized by a controlled reduction of metabolic rate and body temperature during the resting phase of circadian rhythms. In laboratory mice, daily torpor is induced by dietary caloric restriction. However, it is not known which nutrients are related to daily torpor expression. To determine whether dietary protein is a key factor in inducing daily torpor in mice, we fed mice a protein-restricted (PR) diet that included only one-quarter of the amount of protein but the same caloric level as a control (C) diet...
June 13, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28625348/metabolic-regulation-of-the-pmca-role-in-cell-death-and-survival
#11
REVIEW
Jason I E Bruce
The plasma membrane Ca(2+)-ATPase (PMCA) is a ubiquitously expressed, ATP-driven Ca(2+) pump that is critical for maintaining low resting cytosolic Ca(2+) ([Ca(2+)]i) in all eukaryotic cells. Since cytotoxic Ca(2+) overload has such a central role in cell death, the PMCA represents an essential "linchpin" for the delicate balance between cell survival and cell death. In general, impaired PMCA activity and reduced PMCA expression leads to cytotoxic Ca(2+) overload and Ca(2+) dependent cell death, both apoptosis and necrosis, whereas maintenance of PMCA activity or PMCA overexpression is generally accepted as being cytoprotective...
June 8, 2017: Cell Calcium
https://www.readbyqxmd.com/read/28623525/comparison-of-czt-spect-and-conventional-spect-for-assessment-of-contractile-function-mechanical-synchrony-and-myocardial-scar-in-patients-with-heart-failure
#12
Dayong Wu, Zongyao Zhang, Rongzheng Ma, Feng Guo, Lei Wang, Wei Fang
AIM: The aim of this study was to compare CZT-SPECT (CZT SPECT) to conventional SPECT (C-SPECT) in the assessment of left ventricular myocardial scar, contractile function, and mechanical synchrony in patients with heart failure (HF). METHODS: Fifty-nine patients with HF who were referred for myocardial perfusion/metabolism imaging were enrolled. All patients underwent resting (99m)Tc-MIBI gated myocardial perfusion imaging using a CZT SPECT camera and a C-SPECT camera, respectively, and (18)F-FDG PET myocardial metabolism imaging within three days...
June 16, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28623225/high-peripheral-temperatures-in-king-penguins-while-resting-at-sea-thermoregulation-versus-fat-deposition
#13
Agnes Lewden, Manfred R Enstipp, Baptiste Picard, Tessa van Walsum, Yves Handrich
Marine endotherms living in cold water face an energetically challenging situation. Unless properly insulated these animals will lose heat rapidly. The field metabolic rate of king penguins at sea is about twice that on land. However, when at sea, their metabolic rate is higher during extended resting periods at the surface than during foraging, when birds descend to great depth in pursuit of their prey. This is most likely explained by differences in thermal status. During foraging peripheral vasoconstriction leads to a hypothermic shell, which is rewarmed during extended resting bouts at the surface...
June 16, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28623186/assessment-of-active-video-gaming-using-adapted-controllers-by-individuals-with-physical-disabilities-a-protocol
#14
Laurie A Malone, Sangeetha Padalabalanarayanan, Justin McCroskey, Mohanraj Thirumalai
BACKGROUND: Individuals with disabilities are typically more sedentary and less fit compared to their peers without disabilities. Furthermore, engaging in physical activity can be extremely challenging due to physical impairments associated with disability and fewer opportunities to participate. One option for increasing physical activity is playing active video games (AVG), a category of video games that requires much more body movement for successful play than conventional push-button or joystick actions...
June 16, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28622349/a-randomized-cross-over-study-of-the-acute-effects-of-running-5-km-on-glucose-insulin-metabolic-rate-cortisol-and-troponin-t
#15
Boris Keselman, Marta Vergara, Sofia Nyberg, Fredrik H Nystrom
BACKGROUND: We aimed to study the impact by running 5 km, at maximal speed, on the normal variations of metabolic variables related to glucose, insulin, insulin sensitivity, cortisol, glucagon, Troponin T and metabolic rate. MATERIAL AND METHODS: Five women and 12 men 25.7±5.2 years of age with a body-mass-index of 22.5±2.3 kg/m2 where recruited to run 5 km at individual maximal speed in the morning, and to a corresponding day of rest, followed by standardized breakfast and lunch meals...
2017: PloS One
https://www.readbyqxmd.com/read/28621462/evidence-for-convergent-evolution-of-a-neocortex-like-structure-in-a-late-permian-therapsid
#16
Michael Laaß, Anders Kaestner
The special sensory, motor, and cognitive capabilities of mammals mainly depend upon the neocortex, which is the six-layered cover of the mammalian forebrain. The origin of the neocortex is still controversial and the current view is that larger brains with neocortex first evolved in late Triassic Mammaliaformes. Here, we report the earliest evidence of a structure analogous to the mammalian neocortex in a forerunner of mammals, the fossorial anomodont Kawingasaurus fossilis from the late Permian of Tanzania...
June 16, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28620310/abdominal-binding-improves-neuromuscular-efficiency-of-the-human-diaphragm-during-exercise
#17
Sara J Abdallah, David S Chan, Robin Glicksman, Cassandra T Mendonca, Yuanming Luo, Jean Bourbeau, Benjamin M Smith, Dennis Jensen
We tested the hypothesis that elastic binding of the abdomen (AB) would enhance neuromuscular efficiency of the human diaphragm during exercise. Twelve healthy non-obese men aged 24.8 ± 1.7 years (mean ± SE) completed a symptom-limited constant-load cycle endurance exercise test at 85% of their peak incremental power output with diaphragmatic electromyography (EMGdi) and respiratory pressure measurements under two randomly assigned conditions: unbound control (CTRL) and AB sufficient to increase end-expiratory gastric pressure (Pga,ee) by 5-8 cmH2O at rest...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28616381/anosognosia-for-memory-deficits-in-mild-cognitive-impairment-insight-into-the-neural-mechanism-using-functional-and-molecular-imaging
#18
Patrizia Vannini, Bernard Hanseeuw, Catherine E Munro, Rebecca E Amariglio, Gad A Marshall, Dorene M Rentz, Alvaro Pascual-Leone, Keith A Johnson, Reisa A Sperling
Anosognosia, or loss of insight of memory deficits, is a common and striking symptom in Alzheimer's disease (AD). Previous findings in AD dementia patients suggest that anosognosia is due to both functional metabolic changes within cortical midline structures involved in self-referential processes, as well as functional disconnection between these regions. The present study aims to extend these findings by investigating the neural correlates of anosognosia in the prodromal stage of AD. Here, we used regional brain metabolism (resting state 18-F fluorodeoxyglucose positron emission tomography (FDG-PET)) to unravel the metabolic correlates of anosognosia in subjects with amnestic mild cognitive impairment (aMCI) and subsequently resting state functional magnetic resonance imaging (rs-fMRI) to investigate the intrinsic connectivity disruption between brain regions...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28616366/increased-energy-cost-of-mobility-in-chronic-stroke
#19
Monica C Serra, Margarita S Treuth, Charlene E Hafer-Macko, Alice S Ryan
The purpose of this study was to compare the energy cost of completing mobility-related activities in chronic stroke to the estimated energy cost found in the compendium of physical activities, a resource that estimates and classifies energy cost of various human physical activities. Men (n=18) and women (n=10) with chronic hemiparetic gait (stroke latency: 4 ± 2 years, age: 60.4 ± 1.6 years, BMI: 31.5 ± 1.1 kg/m(2)) participated in the study. Portable energy cost monitoring (COSMED K4b2) was performed during five mobility activities of varying intensity to determine metabolic equivalents (METs, or oxygen consumption in multiples of resting level) for each activity...
December 2016: Journal of Gerontology & Geriatric Research
https://www.readbyqxmd.com/read/28615090/prior-exercise-alters-the-difference-between-arterialised-and-venous-glycaemia-implications-for-blood-sampling-procedures
#20
Robert M Edinburgh, Aaron Hengist, Harry A Smith, James A Betts, Dylan Thompson, Jean-Philippe Walhin, Javier T Gonzalez
Oral glucose tolerance and insulin sensitivity are common measures, but are determined using various blood sampling methods, employed under many different experimental conditions. This study established whether measures of oral glucose tolerance and oral glucose-derived insulin sensitivity (insulin sensitivity indices; ISI) differ when calculated from venous v. arterialised blood. Critically, we also established whether any differences between sampling methods are consistent across distinct metabolic conditions (after rest v...
June 15, 2017: British Journal of Nutrition
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