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less invasive stabilization system

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https://www.readbyqxmd.com/read/29748964/is-augmented-liss-plating-biomechanically-advantageous-over-conventional-liss-plating-in-unstable-osteoporotic-distal-femoral-fractures
#1
Dimitar Todorov, Ivan Zderic, R Geoff Richards, Mark Lenz, Matthias Knobe, Dian Enchev, Asen Baltov, Boyko Gueorguiev, Karl Stoffel
Treatment of complex osteoporotic distal femur fractures with the Less Invasive Stabilization System (LISS) has been associated with high complication rates. The aim of this study was to investigate the biomechanical competence of two different techniques of augmented versus conventional LISS plating. Unstable distal femoral fracture AO/OTA 33-A3 was created via osteotomies in artificial femora simulating osteoporotic bone. Three study groups, consisting of 10 specimens each, were created for instrumentation with either LISS plate, LISS plate with additional polylactide intramedullary graft, or LISS plate plus medial locking plate (double plating)...
May 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29728393/maximizing-growth-yield-and-dispersal-via-quorum-sensing-promotes-cooperation-in-vibrio-bacteria
#2
Eric L Bruger, Christopher M Waters
Quorum sensing (QS) is a form of bacterial chemical communication that regulates cellular phenotypes, including certain cooperative behaviors, in response to environmental and demographic changes. Despite the existence of proposed mechanisms that stabilize QS against defector exploitation, it is unclear if or how QS-cooperators can proliferate in populations of mostly defectors in some model systems. We predicted that growth in fragmented subpopulations could allow QS-cooperators to invade a QS-defector population...
May 4, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29549401/lateral-locked-plating-for-distal-femur-fractures-by-low-energy-trauma-what-makes-a-difference-in-healing
#3
Sang-Min Kim, Jae-Woo Yeom, Hyung Keun Song, Kyu-Tae Hwang, Ji-Hyo Hwang, Je-Hyun Yoo
PURPOSE: The objective of this study is to investigate healing outcome of lateral locked plating for distal femoral fractures caused by low-energy trauma. In addition, we sought to determine predictable factors associated with fracture healing time. METHODS: Seventy-three patients (73 fractures) with distal femur fractures (AO/OTA type 33) caused by low-energy trauma were recruited. The mean age of patients was 69.8 years (range, 43-87 years). All fractures were stabilized by less invasive osteosynthesis with anatomical periarticular locking system...
March 16, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29532586/resonance-frequency-analysis-comparing-two-clinical-instruments
#4
William Becker, Philippe Hujoel, Burton E Becker
BACKGROUND: Numerous studies indicate implants placed immediately after extraction or with minimally invasive procedures have excellent long-term success and survival rates. There is general agreement that implants must be stable after implant placement. This study evaluated implant stability changes from the time of implant placement to second stage (prior to restoration). Resonance frequency analysis (RFA) was determined for two commercially available units (Osstell, Osstell USA, Columbia, MD and Penguin, Penguin Integration Diagnostics, Sweden)...
March 13, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29511971/impact-of-continuous-non-invasive-blood-pressure-monitoring-on-hemodynamic-fluctuation-during-general-anesthesia-a-randomized-controlled-study
#5
Takashi Juri, Koichi Suehiro, Aya Kimura, Akira Mukai, Katsuaki Tanaka, Tokuhiro Yamada, Takashi Mori, Kiyonobu Nishikawa
This study assessed the ability of a continuous non-invasive blood pressure (BP) monitoring system to reduce intra-anesthetic hemodynamic fluctuation compared with intermittent BP cuff measurement. Forty patients undergoing total knee arthroplasty under general anesthesia were enrolled and randomly divided into two groups (Control and CS group). BP management was performed using the same protocol with BP measured by intermittent BP cuff in the Control and that by continuous non-invasive BP monitoring in the CS group...
March 6, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29481645/state-of-the-art-treatment-of-spinal-metastatic-disease
#6
Ori Barzilai, Charles G Fisher, Mark H Bilsky
Treatment paradigms for patients with spine metastases have evolved significantly over the past decade. Incorporating stereotactic radiosurgery into these paradigms has been particularly transformative, offering precise delivery of tumoricidal radiation doses with sparing of adjacent tissues. Evidence supports the safety and efficacy of radiosurgery as it currently offers durable local tumor control with low complication rates even for tumors previously considered radioresistant to conventional radiation. The role for surgical intervention remains consistent, but a trend has been observed toward less aggressive, often minimally invasive, techniques...
February 22, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29424149/-inversive-liss-plate-in-treating-intertrochanteric-and-subtrochanteric-fractures-combined-with-femoral-shaft-fractures
#7
Lei Han, Yun-Gen Hu, Wei-Li Fang, Bo Jin, Shi-Chao Xu
OBJECTIVE: To study clinical effects of inversive LISS(less invasive stabilization system, LISS) plate for the treatment of intertrochanteric and subtrochanteric fractures combined with femoral shaft fractures. METHODS: From January 2012 to January 2015, 24 patients with intertrochanteric and subtrochanteric fractures combined with femoral shaft fractures were treated with inversive LISS plate, included 16 males and 8 females with an average age of 62.5 years old ranged from 35 to 81 years old...
July 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29222631/an-advanced-simulator-for-orthopedic-surgical-training
#8
J Cecil, Avinash Gupta, Miguel Pirela-Cruz
PURPOSE: The purpose of creating the virtual reality (VR) simulator is to facilitate and supplement the training opportunities provided to orthopedic residents. The use of VR simulators has increased rapidly in the field of medical surgery for training purposes. This paper discusses the creation of the virtual surgical environment (VSE) for training residents in an orthopedic surgical process called less invasive stabilization system (LISS) surgery which is used to address fractures of the femur...
February 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29138386/reverse-less-invasive-stabilization-system-liss-plating-for-proximal-femur-fractures-in-poliomyelitis-survivors-a-report-of-two-cases
#9
Chen Yao, Dongxu Jin, Changqing Zhang
BACKGROUND Poliomyelitis is a neuromuscular disease which causes muscle atrophy, skeletal deformities, and disabilities. Treatment of hip fractures on polio-affect limbs is unique and difficult, since routine fixation methods like nailing may not be suitable due to abnormal skeletal structures. CASE REPORT We report one femoral neck fracture and one subtrochanteric fracture in polio survivors successfully treated with reverse less invasive stabilization system (LISS) plating technique. Both fractures were on polio-affected limbs with significant skeletal deformities and low bone density...
November 15, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29137676/a-medium-invasiveness-multi-level-patient-s-specific-template-for-pedicle-screw-placement-in-the-scoliosis-surgery
#10
Farhad Azimifar, Kamran Hassani, Amir Hossein Saveh, Farhad Tabatabai Ghomsheh
BACKGROUND: Several methods including free-hand technique, fluoroscopic guidance, image-guided navigation, computer-assisted surgery system, robotic platform and patient's specific templates are being used for pedicle screw placement. These methods have screw misplacements and are not always easy to be applied. Furthermore, it is necessary to expose completely a large portions of the spine in order to access fit entirely around the vertebrae. METHODS: In this study, a multi-level patient's specific template with medium invasiveness was proposed for pedicle screw placement in the scoliosis surgery...
November 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29134236/-arthroscopic-soft-tissue-stabilization-of-posttraumatic-anterior-shoulder-instability-techniques-limitations-and-long-term-results
#11
REVIEW
B Ockert, N Biermann, W Nebelung, E Wiedemann
Arthroscopic soft tissue stabilization is a well-established and broadly accepted procedure to treat posttraumatic shoulder instability. Advantages in comparison to open stabilization procedures include improved visualization of the structural damage and a less invasive approach. Technical developments in recent years have led to further improvement of the arthroscopic technique for shoulder instability. This article presents a description of principles and new developments as it contains basic techniques including patient positioning, access portals, preparation of the glenoid bone, soft tissue handling and shuttle techniques...
February 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29093793/review-of-cortical-bone-trajectory-evidence-of-a-new-technique
#12
REVIEW
Juan Delgado-Fernandez, Maria Ángeles García-Pallero, Guillermo Blasco, Paloma Pulido-Rivas, Rafael G Sola
This article summarizes recent evidence on the cortical bone trajectory (CBT) obtained from published anatomical, biomechanical, and clinical studies. CBT was proposed by Santoni in 2009 as a new trajectory that can improve the fixation of pedicle screws in response to screw loosening in osteoporotic patients. Recently, research interest has been growing with increasing numbers of published series and frequent reports of new applications. We performed an online database search using the terms "cortical bone trajectory," "pedicle screw," "CBT spine," "CBT fixation," "MISS CBT," and "traditional trajectory...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29073792/alendronate-loaded-biodegradable-smart-hydrogel-a-promising-injectable-depot-formulation-for-osteoporosis
#13
Noha Nafee, Mariam Zewail, Nabila Boraie
Alendronate (ALN) is a BCS III bone resorption inhibitor, with very poor oral bioavailability. Our approach is to develop a minimally invasive thermogelling system for prolonged local delivery of ALN. For this, different chitosan-based thermogels were developed and characterised in terms of gelation time, injectability, pH, viscosity and thermoreversibility. Chitosan/β-glycerophosphate (CS/βGP) hydrogel pursued temperature-dependent, thermoreversible gelation behaviour and was thus selected for drug loading...
October 26, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/29060665/robust-motion-artefact-resistant-circuit-for-calculation-of-mean-arterial-pressure-from-pulse-transit-time
#14
Tinish Bhattacharya, Ankesh Gupta, Salam ThoiThoi Singh, Sitikantha Roy, Anamika Prasad
Cuff-less and non-invasive methods of Blood Pressure (BP) monitoring have faced a lot of challenges like stability, noise, motion artefact and requirement for calibration. These factors are the major reasons why such devices do not get approval from the medical community easily. One such method is calculating Blood Pressure indirectly from pulse transit time (PTT) obtained from electrocardiogram (ECG) and Photoplethysmogram (PPG). In this paper we have proposed two novel analog signal conditioning circuits for ECG and PPG that increase stability, remove motion artefacts, remove the sinusoidal wavering of the ECG baseline due to respiration and provide consistent digital pulses corresponding to blood pulses/heart-beat...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29052539/engineering-diagnostic-and-therapeutic-gut-bacteria
#15
Brian P Landry, Jeffrey J Tabor
Genetically engineered bacteria have the potential to diagnose and treat a wide range of diseases linked to the gastrointestinal tract, or gut. Such engineered microbes will be less expensive and invasive than current diagnostics and more effective and safe than current therapeutics. Recent advances in synthetic biology have dramatically improved the reliability with which bacteria can be engineered with the sensors, genetic circuits, and output (actuator) genes necessary for diagnostic and therapeutic functions...
October 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/29030303/electrospun-formulations-of-bevacizumab-for-sustained-release-in-the-eye
#16
Ukrit Angkawinitwong, Sahar Awwad, Peng T Khaw, Steve Brocchini, Gareth R Williams
Medicines based on vascular endothelial growth factor (VEGF) neutralising antibodies such as bevacizumab have revolutionized the treatment of age related macular degeneration (AMD), a common blinding disease, and have great potential in preventing scarring after surgery or accelerating the healing of corneal injuries. However, at present frequent invasive injections are required to deliver these antibodies. Such administration is uncomfortable for patients and expensive for health service providers. Much effort is thus focused on developing dosage forms that can be administered less frequently...
December 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28887570/the-salivary-microbiome-is-consistent-between-subjects-and-resistant-to-impacts-of-short-term-hospitalization
#17
Damien J Cabral, Jenna I Wurster, Myrto E Flokas, Michail Alevizakos, Michelle Zabat, Benjamin J Korry, Aislinn D Rowan, William H Sano, Nikolaos Andreatos, R Bobby Ducharme, Philip A Chan, Eleftherios Mylonakis, Beth Burgwyn Fuchs, Peter Belenky
In recent years, a growing amount of research has begun to focus on the oral microbiome due to its links with health and systemic disease. The oral microbiome has numerous advantages that make it particularly useful for clinical studies, including non-invasive collection, temporal stability, and lower complexity relative to other niches, such as the gut. Despite recent discoveries made in this area, it is unknown how the oral microbiome responds to short-term hospitalization. Previous studies have demonstrated that the gut microbiome is extremely sensitive to short-term hospitalization and that these changes are associated with significant morbidity and mortality...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28858719/liposome-supported-enzymatic-peritoneal-dialysis
#18
Anna Pratsinis, Stefanie Zuercher, Vincent Forster, Eric J Fischer, Paola Luciani, Jean-Christophe Leroux
Compared to hemodialysis, peritoneal dialysis represents a more straightforward and less invasive alternative, though current solutions are not as effective. Herein, the feasibility of liposome-supported enzymatic peritoneal dialysis (LSEPD) is explored to increase the functionality of peritoneal dialysis for the model indication acute alcohol poisoning. Enzyme-loaded liposomes (E-Liposomes) containing alcohol metabolizing enzymes, alcohol oxidase and catalase, are developed and their in vitro and in vivo performances investigated...
August 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28796072/one-visualization-simulation-operation-system-for-distal-femoral-fracture
#19
Dan Wang, Ning Li, Ming Luo, Yao-Kun Chen
A computer-aided 3-dimensional (3D) visualization operation simulation system based on computer-aided design (CAD) Unigraphics NX and Mimics software was established to provide orthopedic surgeons with an actual and reliable system in treating of distal femoral fracture.According to the preoperative CT data, 3D reconstruction of the distal femoral fracture could be achieved by the Mimics software. Then, the CAD Unigraphics NX software was used to measure the model function of all the related surgical instruments, including less invasive stabilization system (LISS) and retrograde intramedullary nail fixation...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28676464/endonasal-endoscopic-odontoidectomy-in-ventral-diseases-of-the-craniocervical-junction-results-of-a-multicenter-experience
#20
MULTICENTER STUDY
Salvatore Chibbaro, Helene Cebula, Sorin Aldea, Bertrand Baussart, Leonardo Tigan, Julien Todeschi, Antonio Romano, Mario Ganau, Christian Debry, Franco Servadei, Francois Proust, Stephane Gaillard
BACKGROUND: Over the past decades, supported by preliminary anatomic and clinical studies exploring its feasibility and safety, experience has increased of the use of the endoscopic endonasal approach (EEA) to ventral diseases at the craniocervical junction (CCJ). METHODS: A multicenter study was carried out over a 4-year period of 14 patients managed by EEA odontoidectomy for CCJ diseases causing irreducible atlantoaxial dislocation. The surgical setup included an IGS system based on computed tomography and magnetic resonance images fusion, and 0° and 30° angled endoscopes with dedicated endoscopic tools...
October 2017: World Neurosurgery
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