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t1-mapping

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https://www.readbyqxmd.com/read/29159946/extracellular-volume-with-bolus-only-technique-in-amyloidosis-patients-diagnostic-accuracy-correlation-with-other-clinical-cardiac-measures-and-ability-to-track-changes-in-amyloid-load-over-time
#1
Giulia Zumbo, Sharon V Barton, Douglas Thompson, Min Sun, Amna Abdel-Gadir, Thomas A Treibel, Daniel Knight, Ana Martinez-Naharro, Lane Thirusha, Julian D Gillmore, James C Moon, Philip N Hawkins, Marianna Fontana
BACKGROUND: Extracellular volume (ECV) by T1 mapping requires the contrast agent distribution to be at equilibrium. This can be achieved either definitively with a primed contrast infusion (infusion ECV), or sufficiently with a delay postbolus (bolus-only ECV). For large ECV, the bolus-only approach measures higher than the infusion ECV, causing some uncertainty in diseases such as amyloidosis. PURPOSE: To characterize the relationship between the bolus-only and current gold-standard infusion ECV in patients with amyloidosis...
November 21, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29153562/noncontrast-myocardial-t1-mapping-by-cardiac-magnetic-resonance-predicts-outcome-in-patients-with-aortic-stenosis
#2
Heesun Lee, Jun-Bean Park, Yeonyee E Yoon, Eun-Ah Park, Hyung-Kwan Kim, Whal Lee, Yong-Jin Kim, Goo-Yeong Cho, Dae-Won Sohn, Andreas Greiser, Seung-Pyo Lee
OBJECTIVES: The aim of this study was to evaluate whether native T1 value of the myocardium on cardiac magnetic resonance (CMR) could predict clinical events in patients with significant aortic stenosis (AS). BACKGROUND: Although previous studies have demonstrated the prognostic value of focal fibrosis using late gadolinium enhancement (LGE) by CMR in AS patients, the prognostic implication of diffuse myocardial fibrosis by noninvasive imaging remains unknown. METHODS: A prospective observational longitudinal study was performed in 127 consecutive patients with moderate or severe AS (68...
November 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29131444/native-t1-reference-values-for-nonischemic-cardiomyopathies-and-populations-with-increased-cardiovascular-risk-a-systematic-review-and-meta-analysis
#3
REVIEW
Maaike van den Boomen, Riemer H J A Slart, Enzo V Hulleman, Rudi A J O Dierckx, Birgitta K Velthuis, Pim van der Harst, David E Sosnovik, Ronald J H Borra, Niek H J Prakken
BACKGROUND: Although cardiac MR and T1 mapping are increasingly used to diagnose diffuse fibrosis based cardiac diseases, studies reporting T1 values in healthy and diseased myocardium, particular in nonischemic cardiomyopathies (NICM) and populations with increased cardiovascular risk, seem contradictory. PURPOSE: To determine the range of native myocardial T1 value ranges in patients with NICM and populations with increased cardiovascular risk. STUDY TYPE: Systemic review and meta-analysis...
November 13, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29128863/persistent-long-term-structural-functional-and-metabolic-changes-after-stress-induced-takotsubo-cardiomyopathy
#4
Caroline Scally, Amelia Rudd, Alice Mezincescu, Heather Wilson, Janaki Srinivasan, Graham Horgan, Paul Broadhurst, David E Newby, Anke Henning, Dana K Dawson
BACKGROUND : Takotsubo cardiomyopathy is an increasingly recognized acute heart failure syndrome precipitated by intense emotional stress. Although there is an apparent rapid and spontaneous recovery of left ventricular ejection fraction, the long-term clinical and functional consequences of takotsubo cardiomyopathy are ill-defined. METHODS : In an observational case-control study, we recruited 37 patients with prior (>12-month) takotsubo cardiomyopathy, and 37 age-, sex-, and comorbidity-matched control subjects...
November 11, 2017: Circulation
https://www.readbyqxmd.com/read/29122631/mitral-valve-prolapse-multimodality-imaging-and-genetic-insights
#5
REVIEW
Purvi Parwani, Jean-Francois Avierinos, Robert A Levine, Francesca Nesta Delling
Mitral valve prolapse (MVP) is a common heritable valvulopathy affecting approximately 2.4% of the population. It is the most important cause of primary mitral regurgitation (MR) requiring surgery. MVP is characterized by fibromyxomatous changes and displacement of one or both mitral leaflets into the left atrium. Echocardiography represents the primary diagnostic modality for assessment of MVP. Accurate quantitation of ventricular volumes and function for surgical planning in asymptomatic severe MR can be provided with both echocardiography and cardiac magnetic resonance ...
November 6, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29121086/improved-segmented-modified-look-locker-inversion-recovery-t1-mapping-sequence-in-mice
#6
Maryam Nezafat, Isabel T Ramos, Markus Henningsson, Andrea Protti, Tamer Basha, René M Botnar
OBJECT: To develop and evaluate a 2D modified Look-Locker (MOLLI) for high-resolution T1 mapping in mice using a 3T MRI scanner. MATERIALS AND METHODS: To allow high-resolution T1 mapping in mice at high heart rates a multi-shot ECG-triggered 2D MOLLI sequence was developed. In the proposed T1 mapping sequence the optimal number of sampling points and pause cardiac cycles following an initial adiabatic inversion pulse was investigated in a phantom. Seven native control and eight mice, 3 days post myocardial infarction (MI) after administration of gadolinium were scanned...
2017: PloS One
https://www.readbyqxmd.com/read/29117484/carotid-intraplaque-hemorrhage-imaging-with-quantitative-vessel-wall-t1-mapping-technical-development-and-initial-experience
#7
Haikun Qi, Jie Sun, Huiyu Qiao, Shuo Chen, Zechen Zhou, Xinlei Pan, Yishi Wang, Xihai Zhao, Rui Li, Chun Yuan, Huijun Chen
Purpose To develop a three-dimensional (3D) high-spatial-resolution time-efficient sequence for use in quantitative vessel wall T1 mapping. Materials and Methods A previously described sequence, simultaneous noncontrast angiography and intraplaque hemorrhage (SNAP) imaging, was extended by introducing 3D golden angle radial k-space sampling (GOAL-SNAP). Sliding window reconstruction was adopted to reconstruct images at different inversion delay times (different T1 contrasts) for voxelwise T1 fitting. Phantom studies were performed to test the accuracy of T1 mapping with GOAL-SNAP against a two-dimensional inversion recovery (IR) spin-echo (SE) sequence...
November 8, 2017: Radiology
https://www.readbyqxmd.com/read/29107626/mri-measurements-of-blood-brain-barrier-function-in-dementia-a-review-of-recent-studies
#8
REVIEW
Rajikha Raja, Gary A Rosenberg, Arvind Caprihan
Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating transport of most molecules to protect the brain microenvironment. Multiple structural and functional components preserve the integrity of the BBB. Several imaging modalities are available to study disruption of the BBB. However, the subtle changes in BBB leakage that occurs in vascular cognitive impairment and Alzheimer's disease have been less well studied. Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is the most widely adopted non-invasive imaging technique for evaluating BBB breakdown...
October 28, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29097350/t1-mapping-and-magnetic-resonance-elastography-potential-new-techniques-for-quantification-of-parenchymal-changes-in-hepatic-amyloidosis
#9
Elif Peker, Ayşe Erden
No abstract text is available yet for this article.
November 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29091750/t1-shortening-in-the-globus-pallidus-after-multiple-administrations-of-gadobutrol-assessment-with-a-multidynamic-multiecho-sequence
#10
Koung Mi Kang, Seung Hong Choi, Moonjung Hwang, Tae Jin Yun, Ji-Hoon Kim, Chul-Ho Sohn
Purpose To determine the association between the administration of the macrocyclic contrast medium gadobutrol and T1 relaxation time in the brains of patients with normal renal function by using multidynamic multiecho (MDME) magnetic resonance (MR) imaging sequences. Materials and Methods The institutional review board approved this retrospective study, and the need to obtain written informed consent was waived. This study included 46 patients (revealed by an electronic medical record search) who had received one or more gadobutrol injections and a maximum of one MR imaging contrast medium injection other than gadobutrol before MDME sequence acquisition...
November 1, 2017: Radiology
https://www.readbyqxmd.com/read/29084397/cardiac-remodelling-in-patients-undergoing-in-centre-nocturnal-haemodialysis-results-from-the-midnight-study-a-non-randomized-controlled-trial
#11
Matthew P M Graham-Brown, Darren R Churchward, Katherine L Hull, Rob Preston, Warren P Pickering, Helen C Eborall, Gerry P McCann, James O Burton
Evidence suggests extended-hours haemodialysis (HD) may improve cardiovascular, medical and quality-of-life outcomes. In-centre nocturnal haemodialysis (INHD) is an established but underutilized method of providing extended-hours treatment. This 6-month, non-randomized controlled trial (ISRCTN16672784) recruited 13 INHD patients and 12 control patients on conventional HD. The effects of treatment on left ventricular (LV) structure, function and myocardial fibrosis were assessed using cardiac magnetic resonance imaging and native T1 mapping...
October 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/29083096/compressed-sensing-in-quantitative-determination-of-gag-concentration-in-cartilage-by-microscopic-mri
#12
Nian Wang, Farid Badar, Yang Xia
PURPOSE: To evaluate the potentials of compressed sensing (CS) in MRI quantification of glycosaminoglycan (GAG) concentration in articular cartilage at microscopic resolution. METHODS: T1 -weighted 2D experiments of cartilage were fully sampled in k-space with five inversion times at 17.6 μm resolution. These fully sampled k-space data were re-processed, by undersampling at various 1D and 2D CS undersampling factors (UFs). The undersampled data were reconstructed individually into 2D images using nonlinear reconstruction, which were used to calculate 2D maps of T1 and GAG concentration...
October 30, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29070834/myocardial-changes-in-incident-haemodialysis-patients-over-6-months-an-observational-cardiac-magnetic-resonance-imaging-study
#13
Elaine Rutherford, Kenneth Mangion, Christie McComb, Elizabeth Bell, Samantha Cockburn, Mohammed Talle, Giles Roditi, Paul Welsh, Rosemary Woodward, Aleksandra Radjenovic, Allan D Struthers, Alan G Jardine, Colin Berry, Rajan K Patel, Patrick B Mark
Patients commencing on haemodialysis (HD) have an increased risk of cardiovascular events in the first year after starting HD compared to those patients established on HD longer. Left ventricular (LV) hypertrophy and abnormal myocardial strain predict mortality. There may be changes in the myocardium of incident HD patients over a 6-month period of HD which may explain changes in cardiovascular risk. We used CMR to consider changes in LV mass, myocardial strain and T1 mapping. We examined changes in pre-dialysis highly sensitive troponin T...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29070069/adenosine-stress-cmr-t1-mapping-detects-early-microvascular-dysfunction-in-patients-with-type-2-diabetes-mellitus-without-obstructive-coronary-artery-disease
#14
Eylem Levelt, Stefan K Piechnik, Alexander Liu, Rohan S Wijesurendra, Masliza Mahmod, Rina Ariga, Jane M Francis, Andreas Greiser, Kieran Clarke, Stefan Neubauer, Vanessa M Ferreira, Theodoros D Karamitsos
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with coronary microvascular dysfunction in the absence of obstructive coronary artery disease (CAD). Cardiovascular magnetic resonance (CMR) T1-mapping at rest and during adenosine stress can assess coronary vascular reactivity. We hypothesised that the non-contrast T1 response to vasodilator stress will be altered in patients with T2DM without CAD compared to controls due to coronary microvascular dysfunction. METHODS: Thirty-one patients with T2DM and sixteen matched healthy controls underwent CMR (3 T) for cine, rest and adenosine stress non-contrast T1-mapping (ShMOLLI), first-pass perfusion and late gadolinium enhancement (LGE) imaging...
October 25, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29061184/assessment-of-reverse-remodeling-predicted-by-myocardial-deformation-on-tissue-tracking-in-patients-with-severe-aortic-stenosis-a-cardiovascular-magnetic-resonance-imaging-study
#15
Ji-Won Hwang, Sung Mok Kim, Sung-Ji Park, Eun Jeong Cho, Eun Kyoung Kim, Sung-A Chang, Sang-Chol Lee, Yeon Hyeon Choe, Seung Woo Park
BACKGROUND: The technique of tissue tracking with balanced steady-state free precession cine sequences was introduced, and allowed myocardial strain to be derived directly, offering advantages over traditional myocardial tagging. The aim of this study was to evaluate the correlation between reverse remodeling as an outcome and left ventricular strain using cardiovascular magnetic resonance imaging (CMR) tissue tracking, and to evaluate prediction of reverse remodeling by myocardial deformation in patients with severe aortic stenosis (AS)...
October 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29060157/multi-scale-locally-low-rank-noise-reduction-for-high-resolution-dynamic-quantitative-cardiac-mri
#16
Steen Moeller, Sebastian Weingartner, Mehmet Akcakaya
Evaluation of myocardial T1 times is conventionally limited to a single temporal snapshot of the cardiac cycle, leaving the dependence between functional and tissue characterization unexplored. We recently proposed a technique that alleviates this limitation by acquiring dynamic quantitative myocardial T1 maps. However, tradeoffs between temporal resolution, scan duration and SNR limit the spatial resolution. In this work, we propose a multi-scale locally low rank noise reduction approach without parameter-tuning to enable high acceleration rates in the acquisition, facilitating superior spatial and temporal resolutions in dynamic myocardial T1 mapping...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059292/additional-value-of-native-t1-mapping-in-tissue-characterization-of-cardiac-aspergillosis
#17
Davide Curione, Paolo Ciliberti, Teresa Santangelo, Aurelio Secinaro
No abstract text is available yet for this article.
October 20, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29056394/strategically-acquired-gradient-echo-stage-imaging-part-i-creating-enhanced-t1-contrast-and-standardized-susceptibility-weighted-imaging-and-quantitative-susceptibility-mapping
#18
Yongsheng Chen, Saifeng Liu, Yu Wang, Yan Kang, E Mark Haacke
PURPOSE: To provide whole brain grey matter (GM) to white matter (WM) contrast enhanced T1W (T1WE) images, multi-echo quantitative susceptibility mapping (QSM), proton density (PD) weighted images, T1 maps, PD maps, susceptibility weighted imaging (SWI), and R2* maps with minimal misregistration in scanning times <5min. METHODS: Strategically acquired gradient echo (STAGE) imaging includes two fully flow compensated double echo gradient echo acquisitions with a resolution of 0...
October 19, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29052267/t1-mapping-with-the-variable-flip-angle-technique-a-simple-correction-for-insufficient-spoiling-of-transverse-magnetization
#19
Simon Baudrexel, Ulrike Nöth, Jan-Rüdiger Schüre, Ralf Deichmann
PURPOSE: The variable flip angle method derives T1 maps from radiofrequency-spoiled gradient-echo data sets, acquired with different flip angles α. Because the method assumes validity of the Ernst equation, insufficient spoiling of transverse magnetization yields errors in T1 estimation, depending on the chosen radiofrequency-spoiling phase increment (Δϕ). This paper presents a versatile correction method that uses modified flip angles α' to restore the validity of the Ernst equation...
October 20, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29044903/native-t1-mapping-for-characterization-of-acute-and-chronic-myocardial-infarction-in-swine-comparison-with-contrast-enhanced-mri
#20
Xi Liu, Jiang-Long Hou, Zhi-Gang Yang, Chun-Chao Xia, Lin-Jun Xie, Peng-Fei Ye, Wan-Lin Peng, Lei Li, Meng-Xi Yang, Ying-Kun Guo
BACKGROUND: Both acute and chronic myocardial infarction (AMI and CMI, respectively) exhibit delayed enhancement; however, clinical decision-making processes frequently require the differentiation of these two types of myocardial injury. PURPOSE: To investigate the reliability of AMI and CMI characterization using native T1 mapping and its feasibility for discriminating AMI from CMI. STUDY TYPE: Case-control. ANIMAL MODEL: The study cohort comprised 12 AMI (mean post-MI, 3...
October 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
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