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tachycardia-induced cardiomyopathy

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https://www.readbyqxmd.com/read/27900527/should-all-patients-with-arrhythmogenic-right-ventricular-dysplasia-cardiomyopathy-undergo-epicardial-catheter-ablation
#1
Andreas Müssigbrodt, Elena Efimova, Helge Knopp, Livio Bertagnolli, Nikolaos Dagres, Sergio Richter, Daniela Husser, Andreas Bollmann, Gerhard Hindricks, Arash Arya
BACKGROUND: Epicardial radiofrequency catheter ablation is currently considered as the therapeutic option of choice in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and recurrent ventricular tachycardia (VT). We hypothesised that inducibility of VT may guide the ablation strategy and thereby affect long-term results. Additional epicardial ablation was only performed if VT were still inducible after thorough endocardial ablation. METHODS: The objective was to examine an inducibility-guided ablation approach by comparing the long-term results between endocardial and epi-endocardial radiofrequency catheter ablation of VT in a large cohort of patients with ARVD/C...
November 30, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27882422/predictors-of-pharmacological-therapy-of-ectopic-atrial-tachycardia-in-children
#2
Haiyan Ge, Xiaomei Li, Haiju Liu, He Jiang
Ectopic atrial tachycardia (EAT) is a relatively common type of supraventricular tachycardia in the pediatric population, and it can be resistant to antiarrhythmic drugs and lead to tachycardia-induced cardiomyopathy (TIC) if not properly managed. The purpose of this study was to determine the predictors of the response to pharmacological therapy in children with EAT. From January 2009 to April 2014, 115 children were admitted to our hospital with a diagnosis of EAT and placed on antiarrhythmic drugs. We examined the clinical history, response to therapy, and follow-up of the children...
November 24, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27837305/rate-control-by-transoesophageal-atrial-overdrive-pacing-for-refractory-supraventricular-tachycardia-with-severe-ventricular-dysfunction-a-bridge-to-recovery
#3
C Paech, J Janousek, F Wagner, R A Gebauer
Tachyarrhythmia-induced cardiomyopathy (TIC) is a rare, yet life-threatening phenomenon in children. TIC has been defined as myocardial dysfunction that is entirely or partially reversible after control of the responsible tachyarrhythmia and is typically caused by an incessant supraventricular tachycardia. In cases of unsuccessful termination of the tachycardia, cardiogenic shock may occur. Several authors favour the use of mechanical circulatory support in such cases. Particularly with regard to these partly severe cases, the authors would like to present the option of transoesophageal overdrive pacing (TOP) as a tool for initial heart rate control and hemodynamic stabilization of patients with TIC refractory to conventional strategies of tachycardia termination...
November 11, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27814325/fatal-cardiac-arrest-in-2-children-possible-role-of-ondansetron
#4
Scott M Brenner, Jenny Boucher
INTRODUCTION: Ondansetron is commonly used to treat vomiting in gastroenteritis, but has a United States Food and Drug Administration black box warning for risk of Q wave to T wave time interval (QT) prolongation. We report 2 pediatric cases of fatal refractory cardiac arrest after administration of ondansetron. CASES: A 10-year-old previously healthy boy presented to the emergency room with gastroenteritis symptoms. After intravenous fluids, morphine, antibiotics, and 2 doses of ondansetron, the patient became unresponsive with agonal respirations and a wide complex tachycardia consistent with ventricular tachycardia...
November 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27810292/special-electrophysiological-characteristics-of-pediatric-idiopathic-ventricular-tachycardia
#5
Shuenn-Nan Chiu, Wei-Lun Wu, Chun-Wei Lu, Kun-Lang Wu, Wei-Chieh Tseng, Ming-Tai Lin, Chien-Chih Chang, Jou-Kou Wang, Mei-Hwan Wu
BACKGROUND: Idiopathic ventricular tachycardia (VT) is an important pediatric arrhythmia but relevant studies in Asian cohort are rare. We determined the electrophysiological characteristics and outcomes of this rhythm disturbance. METHODS: From an institutional database, patients aged <18years without structural heart disease who have sustained monomorphic VT (longer than 30s) during 1995-2016 were enrolled. RESULTS: We enrolled 57 idiopathic VT patients (male:female=31:26)...
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27798173/permanent-junctional-reciprocating-tachycardia-a-rare-but-not-to-be-missed-cause-of-cardiogenic-shock-in-adults
#6
Stéphane Boulé, Nicolas Détis, Nicolas Lamblin
We report the case of a 64-year-old woman who was admitted for cardiogenic shock caused by a permanent junctional reciprocating tachycardia. If this incessant and drug-refractory form of tachycardia is a well-known cause of tachycardia-induced cardiomyopathies in infants, its occurrence during adulthood is extremely rare. Catheter ablation is the recommended treatment of this condition.
October 24, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27754950/tachycardia-induced-cardiomyopathy-in-a-43-year-old-man
#7
Yun-Tao Zhao, Lei Wang, Zhong Yi
No abstract text is available yet for this article.
October 18, 2016: Circulation
https://www.readbyqxmd.com/read/27738073/safety-long-term-outcomes-and-predictors-of-recurrence-after-first-line-combined-endoepicardial-ventricular-tachycardia-substrate-ablation-in-arrhythmogenic-cardiomyopathy-impact-of-arrhythmic-substrate-distribution-pattern-a-prospective-multicentre-study
#8
Antonio Berruezo, Juan Acosta, Juan Fernández-Armenta, Alonso Pedrote, Alberto Barrera, Eduardo Arana-Rueda, Andrés Ignacio Bodegas, Ignasi Anguera, Luis Tercedor, Diego Penela, David Andreu, Rosario Jesus Perea, Susana Prat-González, Lluis Mont
BACKGROUND: First-line endoepicardial ventricular tachycardia (VT) ablation has been proposed for patients with arrhythmogenic cardiomyopathy (AC). This study reports procedural safety, outcomes, and predictors of recurrence. METHODS AND RESULTS: Forty-one consecutive patients [12 with left ventricle (LV) involvement, 7 left-dominant] underwent first-line endoepicardial VT substrate ablation. Standard bipolar and unipolar thresholds were used to define low-voltage areas (LVA)...
October 12, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27733494/long-term-outcome-after-catheter-ablation-of-ventricular-tachycardia-in-patients-with-nonischemic-dilated-cardiomyopathy
#9
Daniele Muser, Pasquale Santangeli, Simon A Castro, Rajeev K Pathak, Jackson J Liang, Tatsuya Hayashi, Silvia Magnani, Fermin C Garcia, Mathew D Hutchinson, Gregory G Supple, David S Frankel, Michael P Riley, David Lin, Robert D Schaller, Sanjay Dixit, Erica S Zado, David J Callans, Francis E Marchlinski
BACKGROUND: Catheter ablation (CA) of ventricular tachycardia (VT) in patients with nonischemic dilated cardiomyopathy can be challenging because of the complexity of underlying substrates. We sought to determine the long-term outcomes of endocardial and adjuvant epicardial CA in nonischemic dilated cardiomyopathy. METHODS AND RESULTS: We examined 282 consecutive patients (aged 59±15 years, 80% males) with nonischemic dilated cardiomyopathy who underwent CA. Ablation was guided by activation/entrainment mapping for tolerated VT and pacemapping/targeting of abnormal electrograms for unmappable VT...
October 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27665166/myocardial-strain-in-the-identification-of-tachycardia-induced-cardiomyopathy-unscrambling-the-egg
#10
Peter M Kistler, Andrew J Taylor
No abstract text is available yet for this article.
September 16, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27665160/clinical-utility-of-longitudinal-strain-to-predict-functional-recovery-in-patients-with%C3%A2-tachyarrhythmia-and-reduced-lvef
#11
Kenya Kusunose, Yuta Torii, Hirotsugu Yamada, Susumu Nishio, Yukina Hirata, Hiromitsu Seno, Yoshihito Saijo, Takayuki Ise, Koji Yamaguchi, Takeshi Tobiume, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata
OBJECTIVES: This study sought to assess the time course of presumptive tachycardia-induced cardiomyopathy and the predictors of left ventricular (LV) functional recovery in such patients. BACKGROUND: Tachycardia-induced cardiomyopathy is a potentially reversible cardiomyopathy with effective treatment of the tachyarrhythmia. However, cases without improvement of LV systolic function were found occasionally. The diagnosis of tachycardia-induced cardiomyopathy can be challenging, and the role of echocardiographic imaging in the prediction of LV functional recovery is limited...
September 16, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27646203/a-novel-ryr2-loss-of-function-mutation-i4855m-is-associated-with-left-ventricular-non-compaction-and-atypical-catecholaminergic-polymorphic-ventricular-tachycardia
#12
Thomas M Roston, Wenting Guo, Andrew D Krahn, Ruiwu Wang, Filip Van Petegem, Shubhayan Sanatani, S R Wayne Chen, Anna Lehman
BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an ion channelopathy usually caused by gain-of-function mutations ryanodine receptor type-2 (RyR2). Left ventricular non-compaction (LVNC) is an often genetic cardiomyopathy. A rare LVNC-CPVT overlap syndrome may be caused by exon 3 deletion in RyR2. We sought to characterize the phenotypic spectrum and molecular basis of a novel RyR2 mutation identified in a family with both conditions. METHODS: Several members of an affected family underwent clinical and genetic assessments...
September 8, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27639515/hypovolemia-induced-systolic-anterior-motion-of-the-mitral-valve-in-two-dogs
#13
K Hammes, J Novo Matos, M Baron Toaldo, T Glaus
Systolic anterior (septal) motion of the mitral valve (SAM) is a common secondary phenomenon in hypertrophic cardiomyopathy (HCM) in people and cats. In humans, it is increasingly recognized that SAM may be found in other cardiac and non-cardiac disease states. In small animal cardiology, SAM unassociated with HCM has been described in dogs with mitral valve dysplasia and right ventricular pressure overload. In this report, we describe two cases of dogs where transient SAM was caused by hypovolemia. When SAM was present both dogs showed pseudohypertrophy and tachycardia...
September 14, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/27612549/anti-arrhythmic-strategies-for-atrial-fibrillation-the-role-of-computational-modeling-in-discovery-development-and-optimization
#14
Eleonora Grandi, Mary M Maleckar
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with increased risk of cerebrovascular stroke, and with several other pathologies, including heart failure. Current therapies for AF are targeted at reducing risk of stroke (anticoagulation) and tachycardia-induced cardiomyopathy (rate or rhythm control). Rate control, typically achieved by atrioventricular nodal blocking drugs, is often insufficient to alleviate symptoms. Rhythm control approaches include antiarrhythmic drugs, electrical cardioversion, and ablation strategies...
September 6, 2016: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27557713/diagnostic-value-of-right-ventricular-dysfunction-in-tachycardia-induced-cardiomyopathy-using-cardiac-magnetic-resonance-imaging
#15
Atsushi Okada, Ikutaro Nakajima, Yoshiaki Morita, Yuko Y Inoue, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Koji Miyamoto, Hideo Okamura, Satoshi Nagase, Takashi Noda, Takeshi Aiba, Shiro Kamakura, Toshihisa Anzai, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano
BACKGROUND: Predicting tachycardia-induced cardiomyopathy (TIC) in patients presenting with left ventricular (LV) dysfunction and tachyarrhythmias remains challenging. We assessed the diagnostic value of early right ventricular (RV) dysfunction to predict TIC using cardiac magnetic resonance (CMR) imaging. METHODS AND RESULTS: A total of 102 consecutive patients with newly diagnosed LV dysfunction and atrial tachyarrhythmias were examined. Patients whose LV ejection fraction (EF) improved to ≥50% during a 1-year follow-up were diagnosed with TIC, and with dilated cardiomyopathy (DCM) in those whose did not improve...
September 23, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27521538/can-ventricular-tachycardia-non-inducibility-after-ablation-predict-reduced-ventricular-tachycardia-recurrence-and-mortality-in-patients-with-non-ischemic-cardiomyopathy-a-meta-analysis-of-twenty-four-observational-studies
#16
Jinzhu Hu, Shan Zeng, Qiongqiong Zhou, Wengen Zhu, Zhenyan Xu, Jianhua Yu, Kui Hong
BACKGROUND: At present, the role of ventricular tachycardia (VT) non-inducibility after ablation in patients with non-ischemic cardiomyopathy (NICM) remains controversial. We conducted a meta-analysis of the published literature to assess whether VT non-inducibility after ablation could predict reduced VT recurrence and mortality in patients with NICM. METHODS: PubMed, ScienceDirect, and the Cochrane library were searched for studies evaluating the effects of VT non-inducibility after catheter ablation on the long-term outcome in NICM patients with sustained VT...
November 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27521092/exercise-induced-ventricular-tachycardia-ventricular-fibrillation-in-the-normal-heart-risk-stratification-and-management
#17
REVIEW
Yoav Michowitz, Sami Viskin, Raphael Rosso
Exercise-induced ventricular tachycardia (VT) rarely occurs in the absence of organic heart disease. Idiopathic monomorphic VT has an excellent prognosis. The main aspect of the risk stratification process is recognizing subtle forms of organic heart disease, particularly arrhythmogenic right ventricular cardiomyopathy. Exercise-induced polymorphic VT is potentially malignant. Exercise-induced polymorphic VT has also been seen in mitral valve prolapse. Some patients with stable coronary disease, and even healthy athletes, sometimes have short bursts of polymorphic VT during exercise tests but these arrhythmias are usually not reproducible during repeated testing and have unknown long-term clinical significance...
September 2016: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/27515893/a-clinical-risk-score-to-improve-the-diagnosis-of-tachycardia-induced-cardiomyopathy-in-childhood
#18
Jeremy P Moore, Shuo Wang, Erin L Albers, Jack C Salerno, Elizabeth A Stephenson, Maully J Shah, Andreas Pflaumer, Richard J Czosek, Jason M Garnreiter, Kathryn Collins, Andrew L Papez, Shubhayan Sanatani, Nicole B Cain, Prince J Kannankeril, James C Perry, Ravi Mandapati, Jennifer N A Silva, Seshadri Balaji, Kevin M Shannon
Tachycardia-induced cardiomyopathy (TIC) is a treatable cause of heart failure in children, but there is little information as to which clinical variables best discriminate TIC from other forms of cardiomyopathy. TIC cases with dilated cardiomyopathy (DC) from 16 participating centers were identified and compared with controls with other forms of DC. Presenting clinical, echocardiographic, and electrocardiographic characteristics were collected. Heart rate (HR) percentile was defined as HR/median HR for age, and PR index as the PR/RR interval...
October 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27506821/multicenter-experience-with-catheter-ablation-for-ventricular-tachycardia-in-lamin-a-c-cardiomyopathy
#19
Saurabh Kumar, Alexander F A Androulakis, Jean-Marc Sellal, Philippe Maury, Estelle Gandjbakhch, Xavier Waintraub, Anne Rollin, Pascale Richard, Philippe Charron, Samuel H Baldinger, Ciorsti J Macintyre, Bruce A Koplan, Roy M John, Gregory F Michaud, Katja Zeppenfeld, Frederic Sacher, Neal K Lakdawala, William G Stevenson, Usha B Tedrow
BACKGROUND: Lamin A/C (LMNA) cardiomyopathy is a genetic disease with a proclivity for ventricular arrhythmias. We describe the multicenter experience with percutaneous catheter ablation of sustained monomorphic ventricular tachycardia (VT) in LMNA cardiomyopathy. METHODS AND RESULTS: Twenty-five consecutive LMNA mutation patients from 4 centers were included (mean age, 55±9 years; ejection fraction, 34±12%; VT storm in 36%). Complete atrioventricular block was present in 11 patients; 3 patients were on mechanical circulatory support for severe heart failure...
August 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27462586/dilated-cardiomyopathy-with-graves-disease-in-a-young-child
#20
Yu Jung Choi, Jun Ho Jang, So Hyun Park, Jin-Hee Oh, Dae Kyun Koh
Graves disease (GD) can lead to complications such as cardiac arrhythmia and heart failure. Although dilated cardiomyopathy (DCMP) has been occasionally reported in adults with GD, it is rare in children. We present the case of a 32-month-old boy with DCMP due to GD. He presented with irritability, vomiting, and diarrhea. He also had a history of weight loss over the past few months. On physical examination, he had tachycardia without fever, a mild diffuse goiter, and hepatomegaly. The chest radiograph showed cardiomegaly with pulmonary edema, while the echocardiography revealed a dilated left ventricle with an ejection fraction (EF) of 28%...
June 2016: Annals of Pediatric Endocrinology & Metabolism
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