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https://www.readbyqxmd.com/read/28331490/ranking-of-sites-for-installation-of-hydropower-plant-using-mlp-neural-network-trained-with-ga-a-madm-approach
#1
Benjamin A Shimray, Kh Manglem Singh, Thongam Khelchandra, R K Mehta
Every energy system which we consider is an entity by itself, defined by parameters which are interrelated according to some physical laws. In recent year tremendous importance is given in research on site selection in an imprecise environment. In this context, decision making for the suitable location of power plant installation site is an issue of relevance. Environmental impact assessment is often used as a legislative requirement in site selection for decades. The purpose of this current work is to develop a model for decision makers to rank or classify various power plant projects according to multiple criteria attributes such as air quality, water quality, cost of energy delivery, ecological impact, natural hazard, and project duration...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28330176/molecular-dissection-of-pathway-components-unravel-atisine-biosynthesis-in-a-non-toxic-aconitum-species-a-heterophyllum-wall
#2
Varun Kumar, Nikhil Malhotra, Tarun Pal, Rajinder Singh Chauhan
Aconitum heterophyllum is an important component for various herbal drug formulations due to the occurrence of non-toxic aconites including marker compound, atisine. Despite huge pharmacological potential, the reprogramming of aconites production is limited due to lack of understanding on their biosynthesis. To address this problem, we have proposed here the complete atisine biosynthetic pathway for the first time connecting glycolysis, MVA/MEP, serine biosynthesis and diterpene biosynthetic pathways. The transcript profiling revealed phosphorylated pathway as a major contributor towards serine production in addition to repertoire of genes in glycolysis (G6PI, PFK, ALD and ENO), serine biosynthesis (PGDH and PSAT) and diterpene biosynthesis (KO and KH) sharing a similar pattern of expression (2-4-folds) in roots compared to shoots vis-à-vis atisine content (0-0...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28327302/effect-of-monomer-blend-and-chlorhexidine-adding-on-physical-mechanical-and-biological-properties-of-experimental-infiltrants
#3
Luciana Tiemi Inagaki, Roberta Caroline Bruschi Alonso, Giovana Albamonte Spagnolo Araújo, Eduardo José Carvalho de Souza-Junior, Paula Cristina Anibal, José Francisco Höfling, Fernanda Miori Pascon, Regina Maria Puppin-Rontani
OBJECTIVES: The aim of the study was to evaluate antimicrobial inhibition zone, degree of conversion (DC) and Knoop hardness (KH) of experimental infiltrants. Experimental low viscosity monomer blends were prepared and chlorhexidine diacetate salt (CHX) (0.1% or 0.2%) was added comprising the groups: G1) TEGDMA; G2) TEGDMA/0.1CHX; G3) TEGDMA/0.2CHX; G4) TEGDMA/UDMA; G5) TEGDMA/UDMA/0.1CHX; G6) TEGDMA/UDMA/0.2CHX; G7) TEGDMA/BISEMA; G8) TEGDMA/BISEMA/0.1CHX; G9) TEGDMA/BISEMA/0.2CHX. Icon(®) was used as control group...
December 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28323480/creatine-supplementation-and-doxorubicin-induced-skeletal-muscle-dysfunction-an-ex-vivo-investigation
#4
Eric C Bredahl, David S Hydock
Supplementing the diet with creatine (Cr) to manage chemotherapy-induced skeletal muscle weakness and fatigue has potential, but little has been done exploring it as an intervention. This study examined the effects of Cr on skeletal muscle dysfunction induced by the chemotherapy drug doxorubicin (Dox). Soleus and extensor digitorum longus (EDL) from male Sprague-Dawley rats maintained in an organ bath were incubated in Krebs-Henseleit (KH) buffer with or without creatine monohydrate (25 mM) for 30 min. Skeletal muscle was then incubated in KH buffer with or without Dox (24 μM) for an additional 30 min...
March 21, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28302924/clinical-use-of-venovenous-extracorporeal-membrane-oxygenation
#5
REVIEW
G Wy Ng, H J Yuen, K C Sin, A Kh Leung, K W Au Yeung, K Y Lai
Extracorporeal membrane oxygenation has been used clinically for more than 40 years. The technique provides respiratory and/or circulatory support via venovenous and veno-arterial configurations, respectively. We review the basic physiological principles of extracorporeal membrane oxygenation systems in venovenous extracorporeal membrane oxygenation. Clinical aspects including patient selection, equipment, setup, and specific patient management are outlined. Pros and cons of the use of extracorporeal membrane oxygenation in respiratory failure are discussed...
March 17, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28301294/fubp-kh-domain-proteins-in-transcription-back-to-the-future
#6
Leonie M Quinn
Drosophila genetic studies demonstrate that cell and tissue growth regulation is a primary developmental function of P-element somatic inhibitor (Psi), the sole ortholog of FUBP family RNA/DNA-binding proteins. Psi achieves growth control through interaction with Mediator, observations that should put to rest controversy surrounding Pol II transcriptional functions for these KH domain proteins.
February 16, 2017: Transcription
https://www.readbyqxmd.com/read/28297292/a-comprehensive-evaluation-of-adaptive-daily-planning-for-cervical-cancer-hdr-brachytherapy
#7
Rebecca Meerschaert, Adrian Nalichowski, Jay Burmeister, Arun Paul, Steven Miller, Zhenghui Hu, Ling Zhuang
The purpose of this study was to evaluate adaptive daily planning for cervical cancer patients who underwent high-dose-rate intracavitary brachytherapy (HDR-BT) using comprehensive interfractional organ motion measurements. This study included 22 cervical cancer patients who underwent 5 fractions of HDR-BT. Regions of interest (ROIs) including high-risk clinical tumor volume (HR-CTV) and organs at risk (OARs) were manually contoured on daily CT images. All patients were clinically treated with adaptive daily plans (ADP), which involved ROI delineation and dose optimization at each treatment fraction...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297276/rounded-leaf-end-modeling-in-pinnacle-vmat-treatment-planning-for-fixed-jaw-linacs
#8
Lori A Young, Fei Yang, Ning Cao, Juergen Meyer
During volume-modulated arc therapies (VMAT), dosimetric errors are introduced by multiple open dynamic leaf gaps that are present in fixed diaphragm linear accelerators. The purpose of this work was to develop a methodology for adjusting the rounded leaf end modeling parameters to improve out-of-field dose agreement in SmartArc VMAT treatment plans delivered by fixed jaw linacs where leaf gap dose is not negligible. Leaf gap doses were measured for an Elekta beam modulator linac with 0.4 cm micro-multileaf collimators (MLC) using an A16 micro-ionization chamber, a MatriXX ion chamber detector array, and Kodak EDR2 film dosimetry in a solid water phantom...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296393/mechanism-of-reduction-of-ferric-porphyrins-by-sulfide-identification-of-a-low-spin-fe-iii-sh-intermediate
#9
Kaustuv Mittra, Asmita Singha, Abhishek Dey
The reaction of Fe(III) porphyrin complexes bearing distal hydrogen bonding residues with sulfide/hydrosulfide is kinetically monitored to reveal the presence of an intermediate and a kH/kD of 3.0. This intermediate is trapped at low temperatures and investigated with resonance Raman and electron paramagnetic resonance spectroscopy. The results, corroborated by density functional theory calculations, indicate that this species is a six-coordinate low spin hydrosulfide bound ferric porphyrin. The homolytic cleavage of the Fe(III)-SH bond resulting in the formation of a ferrous porphyrin and hydrosulfide radical (trapped with 5,5-dimethyl-1-pyrrilone-N-oxide) is found to be the overall rate-determining step of the reaction...
March 15, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28296314/effect-of-the-normalized-prescription-isodose-line-on-the-magnitude-of-monte-carlo-vs-pencil-beam-target-dose-differences-for-lung-stereotactic-body-radiotherapy
#10
Dandan Zheng, Qinghui Zhang, Xiaoying Liang, Xiaofeng Zhu, Vivek Verma, Shuo Wang, Sumin Zhou
In lung stereotactic body radiotherapy (SBRT) cases, the pencil beam (PB) dose calculation algorithm is known to overestimate target dose as compared to the more accurate Monte Carlo (MC) algorithm. We investigated whether changing the normalized prescription isodose line affected the magnitude of MC vs. PB target dose differences. Forty-eight patient plans and twenty virtual-tumor phantom plans were studied. For patient plans, four alternative plans prescribed to 60%, 70%, 80%, and 90% isodose lines were each created for 12 patients who previously received lung SBRT treatments...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28293923/infant-formulas-containing-hydrolysed-protein-for-prevention-of-allergic-disease-and-food-allergy
#11
REVIEW
David A Osborn, John Kh Sinn, Lisa J Jones
BACKGROUND: Allergy is common and may be associated with foods, including cow's milk formula (CMF). Formulas containing hydrolysed proteins have been used to treat infants with allergy. However, it is unclear whether hydrolysed formulas can be advocated for prevention of allergy in infants. OBJECTIVES: To compare effects on allergy and food allergy when infants are fed a hydrolysed formula versus CMF or human breast milk. If hydrolysed formulas are effective, to determine what type of hydrolysed formula is most effective, including extensively or partially hydrolysed formula (EHF/PHF)...
March 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28291201/-results-of-residual-ametropia-correction-using-circle-technology-after-femtosecond-laser-smile-surgery
#12
O A Kostin, S V Rebrikov, A I Ovchinnikov, A A Stepanov, Kh P Takhchidi
AIM: to evaluate functional results of reoperation performed according to the CIRCLE technology and using the VisuMax femtosecond laser and MEL-80 excimer laser in cases of regression of the refractive effect after SMILE surgery. MATERIAL AND METHODS: We studied a group of post-SMILE patients. In those, who showed regression of the refractive effect at 1 year, reoperation was performed according to the CIRCLE technology and using the VisuMax femtosecond laser. The corneal flap was separated from the stromal bed and turned aside...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28288955/resting-and-postexercise-heart-rate-detection-from-fingertip-and-facial-photoplethysmography-using-a-smartphone-camera-a-validation-study
#13
Bryan P Yan, Christy Ky Chan, Christien Kh Li, Olivia Tl To, William Hs Lai, Gary Tse, Yukkee C Poh, Ming-Zher Poh
BACKGROUND: Modern smartphones allow measurement of heart rate (HR) by detecting pulsatile photoplethysmographic (PPG) signals with built-in cameras from the fingertips or the face, without physical contact, by extracting subtle beat-to-beat variations of skin color. OBJECTIVE: The objective of our study was to evaluate the accuracy of HR measurements at rest and after exercise using a smartphone-based PPG detection app. METHODS: A total of 40 healthy participants (20 men; mean age 24...
March 13, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28281087/genetic-differentiation-between-upland-and-lowland-populations-shapes-the-y-chromosomal-landscape-of-west-asia
#14
O Balanovsky, M Chukhryaeva, V Zaporozhchenko, V Urasin, M Zhabagin, A Hovhannisyan, A Agdzhoyan, K Dibirova, M Kuznetsova, S Koshel, E Pocheshkhova, I Alborova, R Skhalyakho, O Utevska, Kh Mustafin, L Yepiskoposyan, C Tyler-Smith, E Balanovska
Y-chromosomal variation in West Asian populations has so far been studied in less detail than in the neighboring Europe. Here, we analyzed 598 Y-chromosomes from two West Asian subregions-Transcaucasia and the Armenian plateau-using 40 Y-SNPs and 17 Y-STRs and combined them with previously published data from the region. The West Asian populations fell into two clusters: upland populations from the Anatolian, Armenian and Iranian plateaus, and lowland populations from the Levant, Mesopotamia and the Arabian Peninsula...
April 2017: Human Genetics
https://www.readbyqxmd.com/read/28278587/functionality-of-albumin-derived-perfluorocarbon-based-artificial-oxygen-carriers-in-the-langendorff-heart-%C3%A2
#15
Anna Wrobeln, Klaus D Schlüter, Jürgen Linders, Manfred Zähres, Christian Mayer, Michael Kirsch, Katja B Ferenz
The aim of this study was to prove whether albumin-derived perfluorocarbon-based nanoparticles (capsules) can operate as a novel artificial oxygen carrier in a rat Langendorff-heart perfusion model. Hearts perfused with capsules showed increased left ventricular pressure and rate pressure product compared to hearts perfused with pure Krebs-Henseleit (KH)-buffer. The capsules prevented the myocardium from functional fail when in their absence a noxious ischemia was observed. Capsules did not change rheological properties of KH-buffer and could repeatedly reload with oxygen...
February 8, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28265104/mir-285-yki-mask-double-negative-feedback-loop-mediates-blood-brain-barrier-integrity-in-drosophila
#16
Dong Li, Yanling Liu, Chunli Pei, Peng Zhang, Linqing Pan, Jing Xiao, Songshu Meng, Zengqiang Yuan, Xiaolin Bi
The Hippo signaling pathway is highly conserved from Drosophila to mammals and plays a central role in maintaining organ size and tissue homeostasis. The blood-brain barrier (BBB) physiologically isolates the brain from circulating blood or the hemolymph system, and its integrity is strictly maintained to perform sophisticated neuronal functions. Until now, the underlying mechanisms of subperineurial glia (SPG) growth and BBB maintenance during development are not clear. Here, we report an miR-285-Yorkie (Yki)/Multiple Ankyrin repeats Single KH domain (Mask) double-negative feedback loop that regulates SPG growth and BBB integrity...
March 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28260271/the-short-synacthen-test-and-laboratory-assay-inter-ference
#17
Choy Kw, Choy Kh
No abstract text is available yet for this article.
March 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28251699/the-response-of-growing-native-turkeys-to-different-feed-colours-and-forms
#18
M F Farghly, Kh M Mahrose
A total number of 180 1-day old native turkey chicks were chosen in this study, for evaluating the impacts of using different attracting colours and forms of the offered feed on growth performance, carcass traits and some of health aspects, in a 3 × 2 factorial experimental design. The birds were allocated into three main groups according to feed colour (non-coloured, orange and green feeds), then each main group was divided to three subgroups corresponded to feed form (mash and crumbles feed) respectively...
March 2, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28248040/-technical-features-of-intestinal-ureteroplasty-part-5-bilateral-ureteroplasty
#19
B K Komyakov, V A Ochelenko, T Kh Al-Attar, A Kh Gaziev
AIM: To present the results and the technical features of the various methods of bilateral ileal ureteroplasty. MATERIALS AND METHODS: From 2001 to 2016, 154 patients (mean age 52+/-9.2 years) underwent ileal and appendicular substitution of the ureter and urinary bladder. Study participants comprised 70 (45.4%) men and 84 (54.6%) women. All patients underwent comprehensive examination, including ultrasound, X-ray, radioisotope and endoscopic tests. Bilateral isolated ileal ureteroplasty was performed in 20 patients (40 substituted ureters) whereof in 14, 5 and 1 cases U-shaped, 7-shaped and two separate grafts were used, respectively...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28248015/-technical-features-of-intestinal-ureteroplasty-part-4-yang-monti-ureteric-reconstruction-with-reconfigured-ileal-segment
#20
B K Komyakov, B G Guliev, V A Ochelenko, T Kh Al-Attar, Kh M Mkhanna
AIM: To present the results of ureteroplasty and technical features of ureteric replacement using the Yang-Monti procedure. MATERIAL AND METHODS: From 2001 to 2016, 105 patients underwent intestinal appendiceal ureteroplasty. In 5 (4.8%) cases, ureteric replacement using the Yang-Monti procedure was performed. Among them, 2 and 3 patients had left and right ureter replacement, respectively. RESULTS: Postoperative complications occurred in 2 of the 5 operated patients, and one of them required re-surgery...
November 2016: Urologii︠a︡
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