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https://www.readbyqxmd.com/read/29933484/-modern-management-of-pancoast-tumour
#1
Alessandro Marra
Pancoast or superior pulmonary sulcus tumour is a subset of lung carcinoma that invades the structures of the thoracic inlet - first ribs, distal roots of the brachial plexus, stellate ganglion, vertebrae, and subclavian vessels. The first symptom is usually shoulder pain; consequently, most patients are initially treated for osteoarthritis. Late diagnosis is common. Success of therapy depends on an accurate staging: standard imaging with CT scan of the chest, PET-CT scan, brain MRI are needed to rule out distant metastases, endobronchial ultrasound-guided needle biopsy (EBUS-TBNA) or mediastinoscopy are mandatory for reliable nodal staging...
June 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29933307/impact-of-comorbidity-on-symptoms-and-quality-of-life-among-patients-being-treated-for-breast-cancer
#2
Horng-Shiuann Wu, Jean E Davis, Ling Chen
BACKGROUND: Cancer patients often have other noncancer medical conditions. Presence of comorbidities negatively affects cancer survival. OBJECTIVE: The aim of this study was to investigate comorbidity, risk factors for comorbidity, and how comorbidity was associated with symptoms and quality of life in patients being treated for breast cancer. METHODS: One hundred and one breast cancer chemotherapy outpatients completed this study. Comorbid conditions, weight, height, and smoking status were identified by chart review...
June 22, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29933305/presurgery-and-postsurgery-quality-of-life-and-associated-factors-in-patients-with-malignant-neoplasms-of-the-head-and-neck-a-6-month-follow-up-study
#3
Zhiping Hu, Xiaoling Zhou, Weiwei Duan, Wenge Lei, Min Zhang, Lingxia Zeng
BACKGROUND: Maintenance of good functional status and improvement of quality of life (QOL) in patients with head and neck cancer help to determine the efficacy of anticancer therapies. OBJECTIVE: The aims of this study were to describe the profile of QOL changing over time and evaluate the correlation between anxiety, pain severity, and shoulder and neck function with QOL in patients. METHODS: A prospective cohort study was conducted. Quality of life, neck and shoulder function, anxiety, and pain were assessed at the time of presurgery, 1 week, and 3 and 6 months postsurgery...
June 22, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29933284/reasons-for-prescription-opioid-use-while-playing-in-the-national-football-league-as-risk-factors-for-current-use-and-misuse-among-former-players
#4
Eugene M Dunne, Catherine W Striley, Zachary L Mannes, Breton M Asken, Nicole E Whitehead, Linda B Cottler
OBJECTIVE: Prescription opioid misuse has become a significant public health issue. Previous research has examined predictors of prescription opioid use and misuse among former National Football League (NFL) players. The present study aimed to describe how reasons for prescription opioid use while in the NFL corresponds to use and misuse in retirement. DESIGN: Former NFL players reporting prescription opioid use during their playing careers (N = 336) were included in this secondary data analysis...
June 21, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29933094/phenol-neurolysis-for-management-of-shoulder-spasticity-in-early-recovery-from-traumatic-brain-injury-a-case-report
#5
Manuel F Mas, Craig DiTommaso, Sheng Li
This case describes a 16-year-old boy who suffered a severe traumatic brain injury. The patient gradually recovered but developed debilitating spasticity mainly in left triceps muscle, abnormal positioning of shoulder girdle complex, and shoulder pain. Phenol (6%) was injected to axillary and radial nerves under guidance of electrical stimulation and ultrasound imaging at 10 weeks after initial injury. After injection, triceps spasticity and shoulder pain was immediately reduced and abnormal positions of shoulder girdle complex and elbow joint gradually returned to functional limits over 2 weeks...
June 19, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29932927/administration-of-a-co-crystal-of-tramadol-and-celecoxib-in-a-1-1-molecular-ratio-produces-synergistic-antinociceptive-effects-in-a-postoperative-pain-model-in-rats
#6
Manuel Merlos, Enrique Portillo-Salido, Alex Brenchat, Bertrand Aubel, Jordi Buxens, Angels Fisas, Xavier Codony, Luz Romero, Daniel Zamanillo, José Miguel Vela
Drug combination for the treatment of pain is common clinical practice. Co-crystal of Tramadol-Celecoxib (CTC) consists of two active pharmaceutical ingredients (APIs), namely the atypical opioid tramadol and the preferential cyclooxygenase-2 inhibitor celecoxib, at a 1:1 molecular ratio. In this study, a non-formulated 'raw' form of CTC administered in suspension (referred to as ctcsusp ) was compared with both tramadol and celecoxib alone in a rat plantar incision postoperative pain model. For comparison, the strong opioids morphine and oxycodone, and a tramadol plus acetaminophen combination at a molecular ratio of 1:17 were also tested...
June 19, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29932797/treatment-of-individuals-with-chronic-bicipital-tendinopathy-using-dry-needling-eccentric-concentric-exercise-and-stretching-a-case-series
#7
Amy W McDevitt, Suzanne J Snodgrass, Joshua A Cleland, Mary Becky R Leibold, Lindsay A Krause, Paul E Mintken
OBJECTIVES: To describe the outcomes of 10 patients with chronic biceps tendinopathy treated by physical therapy with the novel approach of dry needling (DN), eccentric-concentric exercise (ECE), and stretching of the long head of the biceps tendon (LHBT). METHODS: Ten individuals reporting chronic anterior shoulder symptoms (> 3 months), pain with palpation of the LHBT, and positive results on a combination of tests including active shoulder flexion, Speed's, Hawkins Kennedy, Neer, and Yergason's tests participated in this case series...
June 22, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29932790/concerns-related-to-the-accurate-identification-of-anterior-derangement-syndrome-in-mechanical-diagnosis-and-therapy-for-low-back-pain-a-case-report
#8
Hiroshi Takasaki, Stephen May
BACKGROUND: In Mechanical Diagnosis and Therapy (MDT), patients with low back pain (LBP) are classified into subgroups to guide a management strategy. A common subgroup where symptoms improve with lumbar extension is labeled posterior derangement syndrome. A less common subgroup where symptoms improve with lumbar flexion is labeled anterior derangement syndrome. CASE PRESENTATION: The patient was a 23-year-old woman with intermittent LBP and discomfort over the left lower extremity was initially diagnosis with posterior derangement syndrome...
June 22, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29932379/safety-and-efficacy-of-a-novel-neurosurgical-enhanced-recovery-after-surgery-protocol-for-elective-craniotomy-a-prospective-randomized-controlled-trial
#9
Yuan Wang, Bolin Liu, Tianzhi Zhao, Binfang Zhao, Daihua Yu, Xue Jiang, Lin Ye, Lanfu Zhao, Wenhai Lv, Yufu Zhang, Tao Zheng, Yafei Xue, Lei Chen, Eric Sankey, Long Chen, Yingxi Wu, Mingjuan Li, Lin Ma, Zhengmin Li, Ruigang Li, Juan Li, Jing Yan, Shasha Wang, Hui Zhao, Xude Sun, Guodong Gao, Yan Qu, Shiming He
OBJECTIVE Although enhanced recovery after surgery (ERAS) programs have gained acceptance in various surgical specialties, no established neurosurgical ERAS protocol for patients undergoing elective craniotomy has been reported in the literature. Here, the authors describe the design, implementation, safety, and efficacy of a novel neurosurgical ERAS protocol for elective craniotomy in a tertiary care medical center located in China. METHODS A multidisciplinary neurosurgical ERAS protocol for elective craniotomy was developed based on the best available evidence...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29931391/pain-in-older-adults-with-dementia-a-survey-across-europe-on-current-practices-use-of-assessment-tools-guidelines-and-policies
#10
REVIEW
S Zwakhalen, R E Docking, I Gnass, E Sirsch, C Stewart, N Allcock, P Schofield
BACKGROUND: We aimed to explore the existing use of pain assessment tools and guidelines, and develop understanding of the practical considerations required to facilitate their use within the nursing home, hospital and community settings. METHODS: A self-administered web-based survey was conducted with nurses, health and social care workers with an interest in the assessment of pain in older adults with cognitive impairment. The survey was distributed to participants in Austria, Belgium, Denmark, Germany, The Netherlands, Switzerland and United Kingdom...
June 21, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29931331/on-a-mechanism-based-approach-to-physical-therapist-management-of-pain-chimenti-rl-frey-law-la-sluka-ka-phys-ther-2018-98-302-314
#11
Asaf Weisman, John Quintner
No abstract text is available yet for this article.
June 19, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29930733/precision-guided-long-acting-analgesia-by-gel-immobilized-bupivacaine-loaded-microsphere
#12
Wenjing Zhang, Cong Ning, Weiguo Xu, Hanze Hu, Mingqiang Li, Guoqing Zhao, Jianxun Ding, Xuesi Chen
Peripheral nerve blockade (PNB) is a conventional strategy for the management of acute postoperative pain. However, the short duration of the associated analgesia and the potential systemic toxicity due to the low molecular weights of local anesthetics limit their application. Methods: An in situ forming injectable Gel-microsphere (Gel-MS) system consisting of PLGA-PEG-PLGA Gel (Gel) and Gel-immobilized bupivacaine-loaded microsphere (MS/BUP) was prepared for precision-guided long-acting analgesia. A series of in vitro characterizations, such as scanning electron microscopy, rheology analysis, confocal laser scanning microscopy, drug release, and erosion and degradation, were carried out...
2018: Theranostics
https://www.readbyqxmd.com/read/29930463/retrobulbar-alcohol-injection-a-forgotten-therapy-for-management-of-painful-blind-eye
#13
Jagdish Bhatia, Bindu Narayanadas, Mathew Varghese, Mohamed Faruk, Albert Alfy Hafez, Neha Bhatia, Arti Bhatia
No abstract text is available yet for this article.
May 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29930433/-cornual-pregnancy-in-2-cases
#14
S Wang, Y Zhang, Y Y Zhao, S Lu
Cornual pregnancy is one of the diseases caused by embryo embedment at abnormal site. Since few women with cornual pregnancy continue to a middle or late gestation are at a relatively increased risk of uterus rupture,placenta accrete,postpartum hemorrhage and some other severe obstetric complications. We reported two cases of cornual pregnancy at the third trimester, including their clinical symptoms, diagnoses, treatments and obstetric outcomes. Patient 1 had regular prenatal examination. The ultrasound scan at the second trimester showed that the placenta was located at the right fundus of uterus and the myometrium was thin...
June 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29930165/posterior-root-medial-meniscus-reconstruction-an-option-in-chronic-posterior-root-meniscal-injury-management
#15
Renaldi Prasetia, Bancha Chernchujit
Posterior root medial meniscus (PRMM) tears have shown to be biomechanically equivalent to complete meniscectomy. Drawbacks from PRMM tears repair are unsatisfactory healing rates. In this case report, we outlined a PRMM reconstruction with gracilis graft healing outcome in chronic PRMM tear case, based on clinical and MRI evaluation. A 60-year-old man reported a chief complaint of increasing pain on the right knee joint in the last 1 year after a deep-flexion injury. On MRI investigation, we confirmed the chronic PRMM tear as Osteoarthritis Kellgren-Lawrence grade II...
June 20, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29929886/the-experiences-of-pre-and-in-hospital-care-in-patients-with-hip-fractures-a-study-based-on-critical-incidents
#16
Bodil Ivarsson, Ami Hommel, Magnus Sandberg, Desirée Sjöstrand, Anders Johansson
BACKGROUND: Hip fractures are described to have a significant impact on patients' well-being and different fast-track concepts could result in a reduction of the patient's psychological and emotional reactions before pre- and intrahospital care. AIMS AND OBJECTIVES: This study aimed to elucidate perceived situations of significance experienced by patients with hip fracture during the prehospital- and in-hospital care. DESIGN: The study used a qualitative approach using a critical incident technique (CIT), 14 patients with hip fractures were included...
May 15, 2018: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/29929839/management-of-headache-and-chronic-pain-in-pots
#17
REVIEW
Glen A Cook, Paola Sandroni
Primary headache syndromes and chronic pain syndromes are common in patients with postural tachycardia syndrome (POTS). There is overlap in potential mechanisms for migraine, chronic pain, and POTS symptomatology. Management of chronic pain and headaches in POTS requires a judicious use of pharmacotherapies that takes into account patient comorbidities and co-existing symptoms. Patient-centric, non-pharmacologic modalities include physical exercise, cognitive behavioral therapies, and treatment of sleep disorders...
June 12, 2018: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/29929691/challenges-in-plate-fixation-of-chest-wall-injuries
#18
Niloofar Dehghan
Unstable chest wall injuries can result from multiple rib fractures or a flail chest, and are associated with high rates of morbidity and mortality. Traditionally such injuries have been treated non-operatively, with mechanical ventilation when required, and pain management. Surgical treatment of these fractures is technically possible, and studies suggest improved outcomes, such as lower time on mechanical ventilation and length of time in the intensive care unit, compared to non-operative treatment. However, there are many challenges and controversies regarding indications for surgical fixation, patient selection, outcomes, and fixation strategy...
June 2018: Injury
https://www.readbyqxmd.com/read/29929563/procyanidins-attenuate-neuropathic-pain-by-suppressing-matrix-metalloproteinase-9-2
#19
Cailong Pan, Chaoyu Wang, Li Zhang, Ling Song, Yuan Chen, Bingqian Liu, Wen-Tao Liu, Liang Hu, Yinbing Pan
BACKGROUND: Management of neuropathic pain is a real clinical challenge. Despite intense investigation, the mechanisms of neuropathic pain remain substantially unidentified. Matrix metalloproteinase (MMP)-9 and MMP-2 have been reported to contribute to the development and maintenance of neuropathic pain. Therefore, inhibition of MMP-9/2 may provide a novel therapeutic approach for the treatment of neuropathic pain. In this study, we aim to investigate the effect of procyanidins (PC), clinically used health product, on MMP-9/2 in neuropathic pain...
June 21, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29929349/neuropathic-cancer-pain-prevalence-pathophysiology-and-management
#20
So Young Yoon, Jeeyoung Oh
Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, radiotherapy, and surgery; the prevalence is reported to be as high as 40%. The etiologies of NCP include direct nerve invasion or nerve compression by the cancer, neural toxicity, chemotherapy, and radiotherapy. NCP is subdivided into plexopathy, radiculopathy, and peripheral neuropathies, among several other categories. The clinical characteristics of NCP differ from those of nociceptive pain in terms of both the hypersensitivity symptoms (burning, tingling, and an electrical sensation) and the hyposensitivity symptoms (numbness and muscle weakness)...
June 25, 2018: Korean Journal of Internal Medicine
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